1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Title: Defence Mechanisms Starter (from the end of last lesson) • 1.What are the similarities between a virus and bacteria? • 2. What are the main differences between a virus and bacteria? • 3. Draw a flow diagram to explain how viruses replicate. • 4. Name three viral diseases. • 5. Why are viral diseases much harder to treat than bacterial diseases? 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Ways of Spreading Diseases There are four main ways that pathogens are spread from one person to another. •Droplet Infection •Direct Contact •Contaminated Food and Drink •Through a break in the skin 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Droplet Infection • When you cough, sneeze or talk, tiny droplets full of pathogens are expelled into the air. Other people breathe these in. • E.g. Tuberculosis, Influenze, Common Cold 1. How are diseases spread? 2.How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Direct Contact • Some diseases spread by direct contact of the skin. • e.g. Impetigo, Genital Herpes 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Contaminated Food and Drink • Eating raw or undercooked food, or drinking water containing sewage can spread disease. • E.g. Salmonella, Cholera 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Through a Break in the Skin Pathogens can enter the body through cuts, scratches and needle punctures E.g. HIV, Hepatitis 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Task 1 • Describe the four main ways in which infectious diseases are spread. 1. How are diseases spread? 2.How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Preventing Microbes Getting In • There are three main barriers to infection. •The Skin •Scabbing •Mucus and Stomach Acid 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Preventing Microbes Getting In • The skin prevents bacteria and viruses from getting to your tissues underneath. 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Preventing Microbes Getting In • If you cut your skin, you bleed. Your blood quickly clots and forms a scab. This prevents any pathogens from entering. 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Preventing Microbes Getting In • When you breathe, you draw in air full of pathogens. Your breathing system produces mucus which traps them. 1. How are diseases spread? 2.How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Preventing Microbes Getting In • The mucus can then be removed from the body (blowing your nose) or swallowed into the gut, where stomach acid destroys the pathogens. 1. How are diseases spread? 2.How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Task 2 • Copy and complete the following table Barrier Skin Scabbing Mucus and Stomach Acid How it protects against infection 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms How White Blood Cells Protect Against Disease • Some pathogens still get through the barriers to infection. The body however has a second line of defence - the white blood cells of the immune system. 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms How White Blood Cells Protect Against Disease • White blood cells protect fight pathogens in three main ways. •Ingesting Microorganisms •Producing Antibodies •Producing Antitoxins 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Ingesting Microorganisms • Some white blood cells ingest (take in) pathogens, destroying them so they can’t make you ill. 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Producing Antibodies • Some white blood cells produce antibodies that bind to antigens on bacteria and viruses and destroy them. 1. How are diseases spread? 2. How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Producing Antibodies • Once your white blood cells have made an antibody for a specific pathogen, if you get reinfected, these antibodies can be made very quickly. This is immunity. 1. How are diseases spread? 2.How does your body stop pathogens getting in? 3. How do white blood cells protect us from disease? Defence Mechanisms Task 3 • Explain how white blood cells work using combination of sentences and labelled diagrams. – Key words: Antibodies, antigens, antitoxins,