Siva Arunasalam, M.D.
High Desert Heart Institute
ProArgi-9+ Active HDHI Study
• 9 Healthy Subjects + Dan Austin
• Ages: 22-54 + d60an
ProArgi-9+ Active HDHI Study
• Measure lactic acid levels during vigorous exercise
• Lactic acid accumulates when body goes into oxygen
debt
• More vigorous the exercise the longer the duration of
exercise, higher the lactic acid accumulation
• Lactic Acid causes muscle fatigue
• Lactic acid accumulation decreases muscle
performance
ProArgi-9+ Active HDHI Study
Hypothesis:
If L-Arginine increases muscle blood flow, then
there will be less lactic acid accumulation.
Thus increasing endurance & muscle recovery.
ProArgi-9+ Active Formulation
Quercetin: Broad Spectrum Protection
• Blocks oxidation of LDL cholesterol
• Multiple studies performed with 100-200mg. with benefits
including helping maintain BP already in normal range
• Ingredients of PA9Active have more than 200mg. per
serving of Quercetin
• Protection: Antioxidant against factors such as
oxidative stress, radiation, cell damage
Quercetin
Mechanism of Action
• Free Radical scavenger (Antioxidant)
• Promotes a healthy inflammation response,
especially in fat tissue
• Regulates gene expression
• Supports natural stress responses
• Boosts immunity
• Source of Quercetin: Grape skins, Red Onions,
Green Tea to Tomatoes --> Flavonoids
ProArgi-9+ Active HDHI Study
• Study Design
• Subjects exercised maximally with and
without ProArgi-9+ Active (Control)
• Lactic acid was measured pre,
immediately, 15 min, and 30 min post
exercise
• ProArgi-9+ Active was given 60 min
before exercise in study
ProArgi-9+ Active Results
120
100
control
80
Pro Active
60
40
20
0
Pre
0 mins
15 mins
30 mins
ProArgi-9+ Active Results
Endurance in min. 15% increase with ProArgi9+ Active
Subject
Control
ProArgi-9+ Active
1
18
23
2
29
36
3
40
46
4
20
25
5
9
11
6
9
11
7
28
32
8
14
17
9
56
64
10
39
43
ProArgi-9+ Active
Low level exercise vs. High Intensity Exercise
100
80
60
40
pre
20
0 mins
0
15min
control
pro active
control H
low
L
pro active
H
WE GET A
D
84% of patients Screened for Vitamin D3 were deficient:
• 18% < 10
• 32% 10-20
• 34% 21-29
• N=1038
WE GET A
D
• Average replacement instituted at HDHI
3500 units/day
• Once target is attained( > 50 ng/dl )
• Then maintenance dose:
2000-2500 units/day
WE GET A
•
•
•
•
•
•
D
BREAST HEALTH
COLON HEALTH
ANTIOXIDANT
BONE HEALTH
IMMUNE SYSTEM
CARDIOVASCULAR HEALTH