Antitubercular Drugs
•
Combination
or
prevent
provide
drug therapy
the
additive
Classification
Alternate
is
the
emergence of
rule
to
Resistance
delay
and
to
effects against Mycobacterium
tuberculosis
:
classification
:
.
The
•
Isoniazid
( is
iii ,
Rifampin
ciii ,
Ethambutol
in
Pyrazinamide
Aminoglycosides
Iii ,
Fluoroquinolones
Isoniazid
intolerant
In
•
used
in
and
the
is
also
important
Ir )
Cyclo serine
(
Rifampin if
but
,
in
the
combination
least
both
drugs may
.
drug
anti tubercular
toxic
drug
safest
.
in
pregnancy
.
:
Fthambutol
brain
iii.
used
Capreomycin
.
Rifampicin
ii.
is
ciii ,
suspected multidrug resistance
be
•
:
ii.
Usually
•
:
are
( IHH )
drugs include
Backup
•
drugs in combination regimen
primary
&
streptomycin do not
barrier
blood
.
streptomycin
the
first line drugs
among
Ethambutol
cross
&
are
not
hepato toxic
.
iiii
Rifampicin is
( in
streptomycin
(
the
is
safest drug in Renal failure
contra
-
indicated
in
pregnancy
.
.
Tetro
eatment
•
:
Regimen for treating
phase
of
2
of
either
4
*
(
6
to
9
months
or
,
followed by
7 months
months
disease
TB
of
have
a
an
continuation
.
total
intensive
treatment )
phase