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Heart Anatomy & Cardiovascular Diseases Overview

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Heart Anatomy
Layers of the Heart
●​ Endocardium: Innermost layer; lines inner chambers and valves.
●​ Myocardium: Actual contractile layer of the heart.
●​ Pericardium: Covers the outer surface of the heart, composed of two layers:
○​ Visceral: Overlies the organ, closely adheres to the heart.
○​ Parietal: Outermost tough fibrous layer.
Heart Valves
●​ Tricuspid Valve: Three-pointed valve located between the right atrium (RA) and right
ventricle (RV).
●​ Mitral/Bicuspid Valve: Two-pointed valve resembling a bishop's miter, located on the
left side of the heart.
●​ Anchoring: Heart valves are anchored in the innermost layer (endocardium).
Chambers of the Heart
●​ Atria: Receiving chambers that receive blood from the vena cava.
○​ Right Atrium: Receives poorly oxygenated blood.
○​ Left Atrium: Receives oxygen-rich blood from the lungs via pulmonary veins.
●​ Ventricles: Pumping chambers that receive blood from the atria.
○​ Left Ventricle: Largest and most muscular; pumps oxygen-rich blood to the
body.
○​ Right Ventricle: Pumps blood to the pulmonary tree for oxygenation.
Coronary Arteries and Cardiac Conduction
Coronary Arteries
●​ Function: Responsible for delivering blood to the heart.
●​ Right Coronary Artery: Supplies blood to the right atrium, right ventricle, and other
structures.
●​ Left Anterior Descending Artery: Supplies the anterior wall of the left ventricle and
other areas.
●​ Left Circumflex Artery: Supplies the left atrium, lateral and posterior surfaces of the left
ventricle.
Cardiac Conduction System
●​ SA Node: Natural pacemaker of the heart with a firing rate of 60-100 bpm.
●​ AV Node: Delays the electrical signal to allow ventricles to fill with blood.
●​ Bundle of His and Purkinje Fibers: Transmit electrical signals to cause ventricular
contraction.
Cardiac Electrophysiology and Pathway
Cardiac Electrophysiology
●​ Properties: Excitability, automaticity, conductivity, contractility, refractoriness.
●​ Depolarization: Stimulation followed by systole; Repolarization: Electrical relaxation.
●​ Systole and Diastole: Represent mechanical contraction and relaxation of the heart.
Cardiac Electrical Stimulation Pathway
●​ SA Node: Initiates electrical signal; AV Node pauses signal for ventricular filling.
●​ Bundle of His and Purkinje Fibers: Transmit signals for ventricular contraction.
●​ Step-by-Step Process: SA node → Atria contraction → AV node delay → Ventricular
contraction.
Cardiac Output and Regulation
Determinants of Cardiac Output
●​ Preload: Volume of blood entering the heart affecting contraction strength.
●​ Contractility: Ability of heart muscles to eject blood effectively.
●​ Afterload: Resistance the left ventricle must overcome to pump blood out.
Regulation of Cardiac Function
●​ Intrinsic Factors: Venous return and preload within the heart.
●​ Extrinsic Factors: Hormonal (thyroid hormones, catecholamines) and nervous (SNS,
PNS) regulation.
Baroreceptors and Chemoreceptors
Baroreceptors
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Location: Found in the aorta (aortic arch) and carotid arteries
Function: Monitor the pressure of ejected blood
High Pressure Response: Activates the Parasympathetic Nervous System (PNS)
Low Pressure Response: Activates the Sympathetic Nervous System (SNS)
Chemoreceptors
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Location: Coordinated in the Cardioregulatory Center in the medulla oblongata
Monitor: Blood pH levels
Acidosis Response: Activates the SNS
Alkalosis Response: Activates the PNS
Risk Factors for Cardiovascular Diseases
Race
●​ Description: Black Americans have a higher incidence of hypertension
●​ Impact: Increased blood pressure leading to vessel wall thickening and potential
complications like aneurysm
Sex and Estrogen Effects
●​ Men vs. Women: Men have higher risk due to lifestyle factors; women's risk increases
post-menopause
●​ Estrogen Effects: Cardioprotective effects include increasing HDL and decreasing LDL
Lifestyle Factors
●​ Sedentary Lifestyle: Increases risk factors for cardiovascular diseases
●​ Faulty Diet: High intake of cholesterol and saturated fats contributes to the risk
Other Risk Factors
●​ Age: Increased risk with aging and family history of coronary atherosclerosis
●​ Cigarette Smoking: Nicotine impacts blood pressure, heart rate, and platelet activation
●​ Type A Personality, Obesity, Diabetes Mellitus, and Stress: Each factor contributes to
cardiovascular risk through various mechanisms
Assessment Findings and Detailed
Assessment
Symptoms and Associated Conditions
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Chest Pain: Indicates myocardial ischemia
Cyanosis: Linked to decreased cardiac output or congenital conditions
Fatigue: Result of poor circulation affecting energy levels
Syncope: Fainting due to low perfusion
Dyspnea: Difficulty in breathing, a common symptom in cardiac issues
Palpitations: Awareness of irregular heartbeats
Detailed Assessment Techniques
●​ Observation: Includes assessing appearance, pillow use, facial expressions, skin color,
and cognitive status
●​ Weight Management: Sudden weight gain may indicate fluid retention
●​ Eye and Skin Assessments: Arcus Senilis and Xanthelasma are indicative of high
cholesterol levels
●​ Tests: Include the Blanch Test, Schamroth Test, and assessment of skin turgor for
elasticity
Cardiac Assessment Techniques
●​ Carotid Arteries: Caution against assessing both simultaneously to avoid vagal
stimulation
●​ Jugular Vein Distention (JVD) Assessment: Use of rulers to measure venous
pressure
●​ Precordium Landmarks & Heart Sounds: Description of normal and abnormal heart
sounds and their locations
Lungs and Abdomen Assessment
●​ Lungs Assessment: Includes findings like tachypnea, crackles, and Cheyne-Stokes
Respirations
●​ Abdomen Assessment: Observations related to obesity, ascites, hepatomegaly, and
auscultation
Diseases Affecting Cardiac Function
Mechanisms of Compensation
●​ SNS Activation, Cardiac Dilation, and RAAS Activation: Responses to decreased
cardiac output
●​ Aldosterone Role: Promotes sodium retention to improve blood volume and perfusion
adequacy
Symptom Analysis for Chest Pain
●​ Causes: Lactic acid buildup during myocardial ischemia, Angina Pectoris, and other
potential origins of chest pain
Esophageal Disorders and
Musculoskeletal Issues
Esophageal Disorders
●​ Hiatal Hernia or Reflux Esophagitis: Characterized by epigastric burning sensation.
●​ Anxiety and Panic Disorders: Often manifest as burning sensations, triggered by
emotions like anger, depression, and anxiety.
Musculoskeletal Problems
●​ Costochondritis: Inflammation of rib connective tissues causing tenderness upon
movement.
Respiratory Manifestations and
Cardiovascular Conditions
Respiratory Manifestations
●​ Dyspnea: Difficulty breathing.
●​ Exertional Dyspnea: Breathing difficulty during exertion, assessed by the ability to
complete sentences.
●​ Orthopnea: Severe dyspnea requiring a 3-point position due to increased blood return to
the heart and lungs when supine.
●​ Paroxysmal Nocturnal Dyspnea (PND): Sudden nighttime breathing difficulty linked to
left-sided heart failure.
Cardiovascular Conditions
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Irregular Heart Rhythm (Dysrhythmias)
Syncope: Fainting due to poor cerebral perfusion.
Nape Pain: Associated with hypertension.
Weight Gain: Linked to conditions like edema and dependent edema.
Valvular Defects and Congenital Heart
Conditions
Mitral Valve and Valvular Assessment
●​ Mitral Valve: An atrioventricular valve prone to regurgitation, causing backflow.
●​ Murmur: Audible in affected valves like aortic, pulmonic, tricuspid, and mitral valves.
●​ Valvular Defect Assessment: Specific landmarks for auscultation of aortic, pulmonic,
tricuspid, and mitral valves.
Congenital Heart Defects
●​ Atrial Septal Defect: Abnormal opening between atria, leading to increased pulmonary
blood flow.
●​ Ventricular Septal Defect: Increased pulmonary blood flow with backflow into the right
ventricle.
●​ Patent Ductus Arteriosus: Failure of fetal artery closure, causing abnormal blood flow.
●​ Coarctation of the Aorta: Narrowing leading to blood flow obstruction.
●​ Tetralogy of Fallot: Combination of four defects causing cyanosis.
●​ Transposition of Great Arteries (TOGA): Abnormal positioning of pulmonary artery and
aorta causing cyanosis.
Laboratory Examinations and Diagnostic
Tests
Cardiac Enzymes & Markers
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CK-MB: Early marker for myocardial infarction.
Troponin I and T: Indicators of cardiac damage.
Lactate Dehydrogenase: Enzyme showing cardiac injury over time.
Myoglobin: Early diagnostic marker for cardiac issues.
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