Learning Objectives At the end of this lesson you should be able to: Identify the important organs in the digestive system and their functions; Trace the pathway of food in the digestive system Appreciate the importance of the digestive processes of the human body. What is the digestive system? Your digestive system is a network of organs that help you digest and absorb nutrients from your food. It includes your gastrointestinal (GI) tract and your biliary system. Your GI tract is a series of hollow organs that are all connected to each other, leading from your mouth to your anus. Your biliary system is a network of three organs that deliver bile and enzymes through to your GI tract your bile ducts. Digestion is the process of mechanically and enzymatically breaking down food into substances for absorption into the bloodstream. Mechanical digestion involves physically breaking down food substances into smaller particles to more efficiently undergo chemical digestion. The role of chemical digestion is to further degrade the molecular structure of the ingested compounds by digestive enzymes into a form that is absorbable into the bloodstream. Why is digestion important? Digestion is important because your body needs nutrients from food and drink to work properly and stay healthy. Your digestive system breaks nutrients into parts small enough for your body to absorb and use for energy, growth, and cell repair. Stages to food processing 1. Ingestion: taking in/eating of food 2. Digestion: breaking down food(mechanically/chemically) into nutrients 3. Absorption: taking in of nutrients by cells 4. Elimination: removal of undigested food and waste products of digestion Organs of the Digestive System Digestion begins immediately in the mouth with both mechanical and chemical digestion. Mechanical digestion in the oral cavity consists of grinding of food into smaller pieces by the teeth, a process called mastication. Chemical digestion in the mouth is minor but consists of salivary amylase (ptyalin, or alphaamylase) and lingual lipase, both contained in the saliva. After sufficient digestion in the oral cavity, the partially digested foodstuff, or bolus, is swallowed into the esophagus Organs of the Digestive System A tube (about 25 cm long) that connects the mouth to the stomach. Located in your throat near your trachea (windpipe), the esophagus receives food from your mouth when you swallow. A series of muscular contractions within the esophagus called peristalsis delivers food to your stomach. Organs of the Digestive System The stomach is the expanded organ located between the esophagus and the small intestine. It is a muscular organ, elastic, pear-shaped organ that is about 30.5 cm long and 15.2 cm wide. The stomach’s capacity is about 1 liter. The stomach performs three functions: stores swallowed food; mixes the food with the digestive juice it reduces; and conveys its contents slowly into the small intestine. Organs of the Digestive System Mechanical digestion in the stomach occurs via peristaltic contractions of the smooth muscle from the fundus towards the contracted pylorus, termed propulsion. There is significant chemical digestion in the stomach. Two types of glands exist in the gastric mucosa that aid in chemical digestion: oxyntic glands and pyloric glands. Organs of the Digestive System The majority of chemical digestion occurs in the small intestine. A muscular tube that is small in diameter (2.5 cm) but approximately 7 meters in length. The muscles of the small intestine mix food with digestive juices from the pancreas, liver, and intestine, and push the mixture forward for further digestion. Organs of the Digestive System The walls of the small intestine absorb water and the digested nutrients into your bloodstream. As peristalsis continues, the waste products of the digestive process move into the large intestine. It secretes enzymes such as maltase, sucrase, and lactase for the digestion into monosaccharides; Organs of the Digestive System Peptidase that digests peptide molecules into amino acids; and nuclease for the digestion of nucleic acids into sugar and nitrogenous bases. By the time food leaves the small intestine, around 90% of all nutrients have been extracted from the food that entered. Organs of the Digestive System The duodenum (25 cm) is the first segment of the small intestine. It’s largely responsible for the continuous breaking-down process. To help break food down, the duodenum receives digestive juices from other organs in your digestive system, including your liver, gallbladder and pancreas. Ducts from these organs feed into the duodenum. The absorption of vitamins, minerals, and other nutrients begins in the duodenum. Organs of the Digestive System The liver produces bile (green liquid) to emulsify fats in the chyme in the small intestine into globules. Bile is stored in the gallbladder. The pancreas secretes digestive enzymes to break down protein, fats, and carbohydrates. It also converts starch into maltose; fats into fatty acids and glycerol; proteins into amino acids; and nucleic acids into nucleotides. Organs of the Digestive System The main function of the jejunum ( 1.4 m) absorption of important nutrients such as sugars, fatty acids, and amino acids. Peristalsis, the involuntary contraction of smooth muscles that moves nutrients through the digestive system, is vigorous and quick in the jejunum. Nutrients absorbed by the jejunum enter the bloodstream, where they can then be distributed to the organs of the body. Organs of the Digestive System The last portion of the small intestine is the ileum , which has fewer villi and basically compacts the leftovers to pass through cecum through large intestine. It absorbs any final nutrients, with major absorptive products being vitamin B12 and bile acids. Organs of the Digestive System Waste products from the digestive process include undigested parts of food, fluid, and older cells from the lining of your GI tract. The large intestine or colon absorbs water and changes the waste from liquid into stool. Peristalsis helps move the stool into your rectum. Water is removed and bacteria break down some undigestible materials, producing important compounds (such as vitamin K and B with water). The concentrated waste material that remains is called feces. Organs of the Digestive System All leftover waste is compacted and stored at the end of the large intestine called the rectum. When full, the anal sphincter loosens and the waste, called feces, passes out of the body through the anus.