Dialysis Prep Assignment Student Name Kelsey Gassett Date 10/24/23 Grade /50 points I. Dialysis /1 A 1. 2. List 3 purposes of dialysis Removes waste and extra fluids in your body to prevent them from building up in the body Keeping safe levels of minerals in your blood, such as potassium, sodium, calcium, and bicarbonate 3. B Helps regulate blood pressure Explain the difference between ultrafiltration and osmosis. Ultrafiltration: water removal occurs through this process by (1) generating a transmembrane pressure, which is greater than the plasma oncotic pressure. (2) by increasing the osmolarity of the dialysate [as in peritoneal dialysis] Osmosis: fluid moves from areas of high concentration to lower water concentration across a semipermeable membrane until equilibrium. (In dialysis excess fluid moves from blood to the dialysate through a membrane until the fluid level is the same between blood and dialysate) II. Physiologic Principles Hemodialysis “Most common” Advantages • More effective clearance of waste • Short time needed for treatment Peritoneal dialysis • Flexible schedule for exchanges • Few hemodynamic changes during and following exchanges • Fewer dietary and fluid restrictions Continuous Renal Replacement Therapy (CRRT) • Applicability in hemodynamically unstable patients, even in the presence of shock • Can be easily set up and ran by regular ISU Staff (avoids the need for specially trained dialysis nurses and technicians • Membranes in CRRT are typically more permeable (allows for the clearance of membranes as large as 20,000-40,000 /3 Disadvantages • Disequilibrium syndrome • Muscle cramps and back pain • Headache • Itching • Hemodynamic and cardiac adverse events (hypotension, cell lysis contributing to anemia, cardiac dysrhythmias) • Infection • Increased risk for subdural and intracranial hemorrhage from anticoagulation and changes in blood pressure during dialysis • Anemia • Access site complications • Protein loss • Peritonitis • Respiratory distress • Inflammatory bowel disease • Bowel perforation • Infection • Weight gain; Discomfort from “carrying_ 12 L in abdomen during dwell time; potential for back pain or development of hernia • requires more intensive anticoagulation which can place pt. at risk for bleeding and electrolyte disturbances •must remain immobile for long periods of time to ensure proper machine function •not available at smaller hospitals, possibly due to high equipment, training, staffing cost, and relatively infrequent utilization. • Has the ability to avoid rebound of compounds removed from the blood compartment which then re-equilibrate from intracellular space to plasma III. Hemodialysis Access A. AV Fistula /1 /1 Complete this table Permanent or Procedure to create temporary? Permanent Surgeon creates an AV fistula by connecting an artery and a vein in the patient’s arm during a minor surgical procedure. Permanent A surgeon places a graft under the skin and connects an artery and a vein by creating a stable access point for dialysis Temporary Inserted into large veins How soon available for dialysis? Requires some time to mature before they can be used for dialysis. Should be available a few weeks-months post-op AV Graft Shorter time needed than fistula, should be ready within a couple weeks. Subclavian or Can be used immediately for femoral catheter dialysis. B. List four causes of decreased blood flow to a fistula or graft which can result in clotting and loss of patency 1. Stenosis is the narrowing of the blood vessel at the site of the fistula or graft. It often occurs due to the formation of scar tissue inside the blood vessel, which leads to reduced blood flow. Common cause of clotting in hemodialysis access. 2. Thrombosis refers to the formation of blood clots within the blood vessel of the fistula or graft. Clots can obstruct blood clots within the blood vessel of a fistula or graft. The clots can obstruct blood flow and lead to loss of patency. Can occur due to various factors, turbulent blood flow, injury to access site, problem with the dialysis procedure. 3. Intimal hyperplasia is the thickening of the inner lining of a blood vessel. It’s a response to the placement of the fistula or the graft leading to narrowing of the vessel and decreased blood flow. 4. Infection and inflammation: infections near the fistula or graft sites can cause inflammation and damage to the vessel walls. Inflammatory response can lead to the information of clots and decreased blood flow. Inadequate hygiene or improper care of the access site can increase the risk of infection and inflammation as well. Regular monitoring, proper care, and timely intervention are essential to prevent and address these issues, ensuring the longevity and effectiveness of fistula and grafts used for hemodialysis. /1 /1 /2 What is a thrill and what is its purpose? Refers to a pulsatile or vibrating sensation that can be felt or sometimes heard over the vascular access site such as an AV fistula or AV Graft. The purpose of checking for a thrill is to ensure the patency and functionality of the vascular access. Which access is most preferred for End Stage Renal Disease and why? AV fistula • long-term patency • lower infection risk • reduced thrombosis risk • lower healthcare cost • preservation of veins • better blood flow Describe client teaching points for care of a permanent access in the following areas: 1. Daily Cleaning: • hand hygiene 2. 3. IV. • access site cleaning: clean daily with mild soap and water. Gently pat dry with a clean, soft cloth. Do not use alcohol-based products as they can dry out and irritate the skin. • Avoid trauma: be careful to avoid trauma or injury to access site, no tight jewelry, or clothing that could put pressure on the site. When to call the Dr: • when there is s/s of infection. Call the doctor if you notice any redness, swelling, warmth, or pus at the access site. • changes in blood flow: if you feel a sudden decrease of blood flow during dialysis or if you do not feel the usual thrill or hear the bruit over access site. (possible clot or stenosis) • bleeding or bruising: if you experience bleeding after needle removal or develop a large bruise call HCP could indicate a bleeding issue or damage to the access. IV stick in the access arm: • avoidance of access arm: make sure to tell all HCP if you have a vascular access site in your arm and request blood draws, injections and iv’s in your other arm. Protect access arm from any trauma or invasive procedures. • educate HCP: advocate for yourself, express the importance of preserving your access site and state the risks associated with accessing the arm with vascular access. • emergency situations: make sure experienced personnel handle the procedure. After any IV sticks, monitor for s/s of infection or bleeding report anything ASAP Generic care for Clients on Dialysis /1 /1 /1 /1 What medications are usually held during dialysis? • potassium sparing diuretics • NSAIDs • potassium supplements • insulin and oral hypoglycemic agents What meds may be given before dialysis? • anticoagulants • anti-hypertensives • erythropoiesis-stimulating agents • calcium supplements • Phosphate binders Why is the client on hemodialysis at risk for bleeding? • anticoagulation during hemodialysis • platelet dysfunction • uremic platelet dysfunction • vascular access • GI bleeding • medications • inadequate dialysis Hypovolemic Shock 1. What is the cause of hypovolemic shock that occurs during dialysis? • Ultrafiltration • hypotension • bleeding • GI bleed • cardiac issues • dehydration • medications 2. What should the nurse assess to detect hypovolemia during dialysis? Include vital signs and clinical signs? .Vital Signs: b/p, hr, rr, temperature • clinical signs Skin condition: cool and pale skin can indicate poor perfusion Diaphoresis (excessive sweating) • LOC Confusion, restlessness, or altered mental status can occur due to decreased cerebral perfusion • urine output Decreased urine output (oliguria) or absence of urine output (anuria) could indicate hypovolemia • capillary refill More than 2 seconds could suggest poor circulation • peripheral edema Sudden reduction in edema can indicate fluid loss but must be distinguished from dehydration • mucous membranes Dry or sticky can be a sign of dehydration • jugular vein distention Increased central venous pressure • weight change Significant decrease in weight during or after dialysis might indicate a rapid fluid removal • assessment of access site Assess for signs of bleeding, hematoma, signs of clotting LABS • Hgb + Hct • electrolyte levels • Patient hx and symptoms: dizziness, weakness, nausea, thirst • Dietary and fluid intake: ask about diet habits and fluid intake to make sure they are consuming adequate fluids between dialysis sessions. 3c. List dietary considerations below /1 Amts allowed for average hemodialysis pt Protein: 0.6 to 0.8 grams per kg of body weight/ day Potassium: 2000-3000mg per day. /1 Reasons for restriction 4 Foods to Avoid for Each Reduced to lower the workload on the kidneys where high potassium levels cause dangerous heart rhythm disturbances. To prevent hyperkalemia, a condition where high potassium levels cause dangerous heart rhythm disturbances 1. Red meat 2. High protein dairy products 3. Organ meats 4. Processed meats 1. Bananas 2. Oranges 3. Potatoes/ Tomatoes 4. high-potassium salt substitutes 1. Dairy Products 2. nuts, seeds 3. colas 4. Processed foods with phosphorus additives 1. excessive consumption of soups 2. excessive consumption of sauces 3. high-water content fruits and veggies like watermelon and cucumbers 4. soda 1. Eggs 2. Fish 3. Poultry (chicken or turkey) Phosphorus: 800-1,000 mg per day To manage phosphorus levels in the blood, which can affect bone health and cardiovascular function. Fluids: 1500-2,000 mL per day. Limited to avoid fluid overload and maintain electrolyte balance. /1 /1 Identify 3 food sources for high biological value proteins /1 /1 What discharge teaching would you do for YOUR client regarding his/her diet? • Sodium Restriction—helps control b/p and fluid balance, reducing the risk of fluid overload and heart problems • Potassium Management—can cause dangerous heart rhythm disturbances. Managing k+ is VITAL FOR HEART HEALTH • phosphorus control—elevated phosphorus levels can lead to bone and heart problems. Phosphate binders help control absorption. • fluid restriction—prevents fluid overload. • protein intake—high quality proteins like eggs, fish, and poultry, but avoid excessive ` • medication management • monitoring and follow up • lifestyle modifications • Emergency Preparedness • emotional support • importance of compliance Complete Lab & Diagnostic Test Information including the rationales Client Common textbook Rationale for Abnormality Result manifestations for (Pathophysiology- be specific)* abnormalities* (must Even if labs normal must include possible complete. manifestations of high and low results even if lab below is normal WBC 4.8 – 6.4 • High: fever, chills, body • Elevated wbc indicates 10.8 MM3 aches, increased heart infection, inflammation or rate, rapid breathing stress, or leukemia. • Low: increased risk of infections, fatigue, • Low wbc can result from bone weakness, mouth sores marrow disorders, autoimmune diseases, or viral infections. Hgb HIGH: headaches, • high rbc, hemoglobin, and 12 –16 (g/L) 10.8 dizziness, itching, hematocrit can signify Hct redness in the face, high polycythemia vera, chronic lung 37 – 47 (%) 32.4 blood pressure disease, or dehydration, or bone LOW: Fatigue, weakness, marrow disorders. RBC pale skin, shortness of 4.2 – 5.4 4.1 breath, cold hands and • low values can indicate mil/mm3 feet anemia due to nutritional deficiencies, chronic diseases, or bone marrow disorders. Na HIGH: thirst, • high sodium results from 135 – 145 145 restlessness, dry mouth, dehydration, diabetes insipidus, mEq/L swollen tongue, or excessive salt intake. confusion • Low sodium can occur due to LOW: nausea, headache, heart failure, kidney disorders, confusion, seizures, or excessive fluid intake. muscle cramps K 3.5 – 5.3 HIGH: irregular • high potassium can be due to mEq/L 4.1 heartbeat, palpitations, kidney failure, medications, or muscle weakness, uncontrolled diabetes numbness, tingling • low potassium may result LOW: muscle weakness from vomiting diarrhea or fatigue, constipation, certain medications irregular heartbeat, numbness Ca (Serum) 8.5 8.2 HIGH: excessive thirst, • high calcium can be caused by – 10.5 mg/dL frequent urination, hyperparathyroidism, cancer, or Ionized 4.5 – abdominal pain, muscle excessive vit D 5.1 mg/dL weakness /20 Test and norms 4. Treatment for the abnormality or to maintain normal value of the client Use Critical thinking with this explanation. Antibiotics, antiviral medications Proper hygiene and infection control Address underlying cause hydration, specific therapies for underlying conditions. Low values may need iron supplements and B12 injections Dehydration + diabetes insipidus: fluid replacement Hyponatremia: fluid restriction or treat underlying condition HF or KD Dietary modifications, medications to enhance potassium excretion, or dialysis in severe cases. Hypokalemia may require potassium supplements, diet changes, adjust medications causing excessive potassium loss Hydration for hyperparathyroidism (treat underlying cause) Hypocalcemia may require calcium supplements and Phos 2.5 – 4.5 mg/dL 6.7 Cholesterol Less than 200 mg 189 Total Protein 6.0 – 8.5 g/dL Albumin 3.4 – 5.0 g/dL 5.8 BUN 6 – 23 mg/dL Creatinine 0.5 – 1.2 mg/dL 3.1 45 4.4 LOW: numbness and tingling, muscle cramps, seizures, brittle nails HIGH: itching, joint pain, bone fractures, confusion • low calcium can result from hypothyroidism, kidney failure, or vitamin D deficiency • high phosphorus can occur in kidney disease, hypothyroidism, or excessive intake. LOW: weakness, fatigue, bone pain, loss of appetite, respiratory failure HIGH: no specific symptoms but a risk factor for heart disease and stroke • Low phosphorus may result from malnutrition, alcoholism, or hyperthyroidism HIGH: dehydration, low urine output, dark urine, dry mouth • High cholesterol levels can indicate a risk for a heart disease and are influenced by diet, genetics, and lifestyle factors. High protein levels can occur due to dehydration or certain diseases. LOW: swelling (edema), muscle wasting, fatigue, weakened immune system HIGH: fatigue, loss of appetite, nausea, confusion, shortness of breath Low protein levels may result from malnutrition, liver or kidney disease, or chronic inflammation Elevated BUN + creatinine suggest impaired kidney function, dehydration, or urinary tract obstruction. LOW: liver disease, malnutrition, overhydration Low values may occur due to liver disease or low protein intake HIGH: fatigue, sob, edema, n/v, muscle cramps, hypertension, pruritus, anemia, neuropathy, confusion + cognitive impairment Elevated BUN + creatinine suggest impaired kidney function, dehydration, or urinary tract obstruction. LOW: muscle weakness, fatigue, altered mental status, loss of appetite, muscle atrophy, hypotension, nausea and diarrhea, cramping, cardiac arrythmias, decreased GFR Glucose 80 – 110 mg/dL 86 HIGH: excessive thirst, frequent urination, fatigue, blurred vision, slow healing wounds LOW: dizziness, shakiness, confusion, sweating, irritability management of underlying disorders like hypothyroidism Dietary restrictions phosphate binders Oral supplements Iv fluids-severe cases Diet and exercise Medications (statins) Adequate hydration Nutritional support Medication adjustments Dietary changes Dialysis –Severe cases Medication adjustments Dietary changes Dialysis –Severe cases Low values may occur due to liver disease or low protein intake high glucose level are indicative of diabetes or stress. Low glucose levels can result from insulinoma, liver disease, or excessive alcohol consumption Insulin PO hypoglycemics Regular monitoring Dietary adjustments CO2 24 – 30.9 mEq/L Mag 1.5 – 2 mEq/L Parathyroid Hormone (PTH) 8 – 24 pg/ml N – Terminal 26 1.7 674 The clinics goal is between 100 and 300 mL HIGH: sob, confusion, drowsiness, increased heart rate High levels of CO2 indicate respiratory acidosis, kidney disease, or certain medications. LOW: dizziness, tingling in the extremities, muscle cramps, confusion HIGH: nausea, vomiting, weakness, hypotension, respiratory distress Low co2 levels suggest metabolic acidosis, dehydration or kidney disorders LOW: muscle cramps, tremors, seizures, abnormal heart rhythms, personality changes HIGH: bone pain, frequent urination, abdominal pain, fatigue, depression Low magnesium can result from malnutrition, alcoholism, or kidney disorders. LOW: numbness, tingling, muscle cramps, seizures, dry skin High magnesium can occur in kidney failure or excessive intake. High PTH levels indicate hyperparathyroidism, kidney disease, or vitamin d deficiency Low PTH suggest hypothyroidism or improper feedback regulation Oxygen therapy Ventilation Managing metabolic disorders Diet changes Supplements Address underlying causes such as kidney disorders Calcium Vitamin D supplements Address malnutrition Manage autoimmune disorders Resources: Med surg book, and diagnostic test book and websites * complete for all labs, regardless of if the client had one drawn or no 6. /1 List two complications that can occur during the client’s dialysis. 1. Hypotension Causes: Rapid removal of fluid during dialysis can lead to a sudden drop in blood pressure. Symptoms: dizziness, lightheadedness, nausea, blurred vision, or fainting Management: slow down fluid removal, adjusting the dialysis prescription, changing the patients position, administer iv fluids if necessary 2. Muscle Cramps Causes: electrolyte imbalance (low potassium, low calcium) and rapid fluid removal Symptoms: painful muscle contractions (legs) Management: adjusting dialysis. Proper hydration, supplement with medications, change diet to accommodate electrolyte imbalances /1 a. List assessments that should be performed immediately before dialysis Vital signs Blood pressure, heart rate, respiratory rate Weight Measure current weight compared to target weight Rational weight. Gain between dialysis sessions can indicate fluid retention, which needs to be removed during dialysis Fluid Status Edema (esp. legs and ankles) Lung sounds (crackles or wheezes might indicate fluid overload) Jugular venous distention Rationale—monitoring fluid status helps determine the appropriate amount of fluid to remove during dialysis. /1 /1 /1 /1 /2 Access site assessment Thrill (vibrations) and bruit (swishing) Site inspection Rationale Lab values Pre-dialysis blood test Rationale Medication review Current medications Rationale Patient assessment Symptoms Overall condition Rationale Dialysis machine and settings Machine checks Dialysis prescriptions Rationale b. Fluid imbalances 1. What is the protocol for treatment of hypovolemia during dialysis? • reducing ultrafiltration rate • iv fluids • monitoring: vs, bp, hr, oxygen saturation What is meant by dry weight? - refers to the ideal weight at which a hemodialysis patient’s fluid balance is optimized, and excess fluid (volume overload) is removed. - Achieving and maintaining dry weight is essential for managing fluid imbalances and preventing complications such as hypertension, edema, and heart failure. How would the nurse explain to the client the need for fluid restriction between dialysis? - Educate on kidney function - Emphasize importance - Individualized plan - Practical tips - Discuss consequences - Encourage communication - Involve family b. List 5 comfort measures the nurse should provide during dialysis 1) Positioning and Support: Proper seating, Cushions and blankets, Frequent position changes 2) Pain management: assessment, pain relief, heat therapy 3) Emotional Support and distraction: emotional support, distraction 4) Hygiene and personal care: oral care, skin care, bathroom assistance 5) Adequate monitoring and communication: regular monitoring, communication Disequilibrium Syndrome c. Discuss in depth the etiology of disequilibrium syndrome? • Osmotic Shift Theory • Urea Re-Entry Theory • Cerebral Blood Flow Theory • Vasogenic Edema Theory • Cytotoxic edema theory More common to patients new to dialysis or have not undergone dialysis for an extended period of time. d. List Signs and symptoms of disequilibrium syndrome: • headache, n/v, agitation + restlessness, altered consciousness, muscle twitching, increased intracranial pressure (ICP), hypertension Renal Transplant 1) /2 /50 Explain the protocol for renal transplant. • evaluation • matching • surgery • recovery • post-transplant care 2) List the pros and cons for choosing to have a renal transplant? • PROS: Improved quality of life: Long-term solution Dietary freedom Potential cost savings Better survival rates • CONS: Risk of rejection Surgery Risks Limited donor supply Side effects of medications Lifestyle adjustments Total: VI. Care during Dialysis