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Metabolism worksheet-1-1
Nutrition (Bellevue College)
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Metabolism Worksheet
Please fill in the following table with detail. Include the metabolic substrate that goes in to as
well as the metabolic substrate the leaves each of the processes below. Identify where each of
these processes take place as well as if there are any items produced (ie: co-enzymes, hydrogen
ions, water, co2, etc). Substate in vs out speaks to what product goes in to this reaction and
what product (s) are produced. Some of these columns may have overlapping material.
Definition
Glycolysis
TCA cycle
Cori Cycle
Breakdown of glucose into
pyruvate.
Catabolic (glucose to
pyruvate) and Anabolic
(pyruvate to glucose)
Cycle of aerobic chemical
reactions. Oxidizes acetyl
CoA.
Is used when ATP is limited
Catabolic and anabolic.
Metabolic pathway in the
liver that regenerates glucose
from lactate released from
the muscle.
Substrate
in/out
In:
Glucose
Out: 2
Pyruvate
Location
Cytoplasm
2 ATP
2 H+
2 NADH
2 H2O
In: Acetyl
CoA
Out:
_______
Mitochondria
matrix
2 CO2
3 NADH + H+
1 FADH2
In: 2
Lactate
Out:
Glucose
Liver
NAD+
NADH
In: Acetyl
CoA
Out:
ketone
bodies
In:
 H
+
 O
2
 N
A
D
H
Liver
Cori Cycle (With Diagram) |
Biochemistry. (2016, October 20).
Retrieved from
http://www.notesonzoology.com/m
etabolism/cori-cycle-with-diagrambiochemistry/4994
Glucose reenters the blood
to the muscles.
Ketosis
(Ketogenesis)
Electron
Transport
Chain
Condition of increased
ketone bodies in the blood.
Formation of ketone bodies.
Catabolic
Series of protein complexes
that produces the majority of
ATP.
Aerobic
Items produced
Inner
mitochondria
membrane
Beta-hydroxybutyrate
NADH
H+
Acetone
CO2
H2O
ATP
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
Beta
Oxidation
Fatty acids are disassembled.
Fatty acid oxidation to acetyl
CoA.
Catabolic
Out: 34
ATP
In: Fatty
Acid
Out:
Acetyl
CoA
FA
D
H
2
Mitochondria
Liver
Muscle
1 FADH2
1 NADH + H+
Blake, J. S., Munoz, K. D., & Volpe, S. (2018). Nutrition: From science to you(4th ed.). Retrieved
from https://bookshelf.vitalsource.com/books/9780134796376
Cori Cycle (With Diagram) | Biochemistry. (2016, October 20). Retrieved from
http://www.notesonzoology.com/metabolism/cori-cycle-with-diagram-biochemistry/4994
1. What is the most metabolically active organ in the human body?
Liver
2. Refer to page 290 of your text, Pyruvate to Lactate. Do 30-40 squats consecutively. What
sensation in your quads are you experiencing? What is causing this sensation to happen and
what metabolic process did you just experience? What is actually causing your uncomfortable
burn?
3. Identify the following as a hormone or enzyme and describe its role in metabolism
a. Insulin
b. Glucagon
c. Cortisol
d. Lipoprotein lipase
e. Hormone sensitive lipase
f. Alcohol dehydrogenase
4. How many acetyl CoA molecules will be created by a fatty acid containing 18 carbons?
9 Acetyl CoA molecules
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5. Which of the metabolic processes in the table above is responsible for the majority of ATP
production
Electron transport chain. Produces about 36 to 38 molecules of ATP.
6. What ergogenic aid (performance enhancing supplement) can help increase the ADP within our
cells to be ‘reenergized’ back in to ATP within our cells? (hint: this is helpful for quick and
explosive movements/exercises)
7. Compare and contrast between anabolic and catabolic reactions. Provide an example of each.
8. Compare and contrast between the absorptive state and post absorptive state
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