NRSG 3302 – Women’s and Family Hormones of Pregnancy Hormone *estrogen Where Secreted Major Actions ovaries-early placenta-over ½ by 7wks *progesterone corpus luteum placenta *hCG (human chorionic gonadotropin) Trophoblast (placenta) relaxin corpus luteum placenta uterine size breast development blood flow Prevents further follicular development during pregnancy relaxes smooth muscle maintains uterine lining for implantation thermogenic during ovulation Prevents involution of corpus luteum, which maintains production of progesterone until the placenta is formed Used to detect early pregnancy initially high in early pregnancy then diminishes uterine contractility relaxes connective tissue both growth promoting and lactogenic (milk producing) acts as antagonist to insulin *hPL (human placental lactogen) placenta *prolactin placenta anterior pituitary affects breast growth and milk production Hormone Where Secreted Major Actions anterior pituitary during pregnancy Produces hyperpigmentation posterior pituitary Stimulates uterine contractions Stimulates the milk ejection reflex Adrenals during pregnancy to conserve sodium and maintain fluid balance cortisol Adrenals during pregnancy, is active in metabolism of glucose and fats May be helpful in preventing rejection of pregnancy because of its antiinflammatory effect thyroxine Thyroid during pregnancy to stimulate basal metabolic rate melanocyte stimulating hormone *oxytocin aldosterone *FSH (follicle stimulating hormone) *LH (luteinizing hormone) Anterior pituitary Anterior pituitary Initiates maturation of ovum, necessary for conception, is suppressed during pregnancy Stimulates ovulation of the mature ovum in the nonpregnant state *= hormones you are responsible for