ACUTE APPENDICITIS By - Muskan Bhardwaj Group 01 INTRODUCTION •Appendicitis is an inflammation of the appendix. ANATOMY ANATOMICAL VARIANTS • Pre-ileal – anterior to the terminal ileum – 1 or 2 o’clock. • Post-ileal – posterior to the terminal ileum – 1 or 2 o’clock. • Sub-ileal – parallel with the terminal ileum – 3 o’clock. • Pelvic – descending over the pelvic brim – 5 o’clock. • Subcecal – below the cecum – 6 o’clock. • Retrocecal – behind the cecum – 11 o’clo ck. • The most common position is retrocecal. • 2nd MC - pelvic • Least common -post ileal. ARTERIAL SUPPLY • The appendix is derived from the embryologic midgut. • The vascular supply is via branches of the superior mesenteric vessels. • Arterial supply is from the appendicular artery (derived from the ileocolic artery, a branch of the superior mesenteric artery) • Accessory - Artery of seshachalam • ( branch of Post. Caecal Artery) VENOUS DRAINAGE • v. appendicularis -----> v. ileocolica----> v. mesenterica superior----> v. portae • Clinical relevance • Portal way of the infection spread – • pilephlebitis (fatal comlication of • appendicitis) LYMPHATIC DRAINAGE • Lymphatic fluid from the appendix drains into lymph nodes within the mesoappendix and into the ileocolic lymph nodes (which surround the ileocolic artery) . NERVOUS SYSTEM • the appendix is innervated by the superior mesenteric plexus, whereas the parasympathetic fibers come from the vagus nerve (cranial nerve X). CLASSIFICATION • I. Acute appendicitis • 1.1. Acute simple (catharral ) appendicitis. • 1.2. Acute destructive appendicitis: • - Flegmonous ; • - Gangrenous ; • - Gangreno -per forative. • 1.3. Complications of the acute appendicitis: • - Peritonitis - localized, generalized; • - Appendicular infiltrat; • - Appendicular abscess; • - Pilephlebitis; • II. Chronic appendicitis – result of the not operated resolved • acute appendicitis. CAUSES • 1- OBSTRUCTIVE CAUSES • FECALITH- a fecal calculus or stone that occlude lumen of the appendix • Twisting or curling or the appendix • Swelling of the bowel wall • Lymphoid hyperplasia • 2- NON-OBSTRUCTIVE CAUSES • Haematogenous spread of infection • Vascular occlusion • Trauma • Diet lacking fibres. PATHOPHYSIOLOGY SYMPTOMS • Abdominal pain (100%) constant, moderately intensive. ( Right lower quadrant) • Epigastric phase(40-50%): first pain in epigastric or umbilical region or all over the abdomen (in children) ---------->after a couple of hours the pain migrates to the right iliac region – symptom of pain • Migration Kocher’s-Wolkowitch’s (only almost pathognomonic symptom of appendicitis). • Pain right away in the right iliac region (50-60%) . • ANOREXIA • Nausea, vomitting (40-50%) 1- 2 times, comes after pain, reflectory. can be absent; • NOTE! if nausea or vomitting before pain - not a appendicitis characteristic; • Tongue firstly wet, then dry. • TACHYCARDIA • NOTE! if dry tongue - sign of dehydration. SIGNS • 1- Tenderness at MCBURNEY'S POINT • 2- POINTING SIGN - patient point towards the site of maximum Tenderness (RT. Iliac fossa) • 3- ROVSING SIGN- pain in RIF when LIF is pressed • 4- PSOAS SIGN/COPE PSOAS/ OBRAZTSOV SIGN - hyperextension of right leg( c/h of retrocaecal appendix) • 5- OBTURATOR SIGN- flexion and internal rotation of right hip. NON-SPECIFIC SIGN • DUNPHRY SIGN - pain on coughing • TEN HORN SIGN - pain in RIF when right testes is pulled • ARON SIGN -pain in RIF when epigastrium is pressed • BLUMBERG SIGN (rebound tenderness ) • Frequent urination ( tip irritates bladder) interpreted as UTI • Diarrhoea and tenesmus • Pain on DRE. DIAGNOSTIC CRITERIA • Alvarado score (a.k.a MANTRELS score) • Score total • 5-6 compatible with acute appendicitis • 7-8 probable acute appendicitis • 9-10 very probable acute appendicitis • ruling out appendicitis with a score <5 than "ruling in" appendicitis with a >7 . • APPEND score -male gender • anorexia • . migratory pain • localised peritonism • . elevated CRP >15 mg/L • . neutrophilia >7.5x109/L • in children, clinicians sometimes use other scores for the same purpose: • paediatric appendicitis score (PAS) • paediatric appendicitis risk calculator (pARC) scor e LABORATORY FINDINGS • 1- Increased TLC( total leucocytes count) 4000 -11000 • 2- Increased neutrophils (2000-7000 / ml) • 3- Increased CRP(0.3-1.0 mg/dl) • IMAGING TEST • IOC- 1-Adults- CECT • 2- Children - USG CECT USG DIFFERENTIAL DIAGNOSIS • inflammatory bowel disease, especially Crohn disease, which may affect the appendix • other causes of terminal ileitis • appendiceal mucocele • lymphoid hyperplasia • pelvic inflammatory disease (PID) • right-sided diverticulitis • appendiceal diverticulitis • Meckel diverticulitis • acute epiploic appendagitis • omental infarction • appendiceal endometriosis • appendiceal malignancy • colorectal cancer • peritoneal metastases • carcinoid • isolated appendiceal submucosal lipomatosis 26 • Valentino syndrome (from perforated peptic ulcer) MANAGEMENT OPEN APPENDICECTOMY LAPAROSCOPIC APPENDICECTOMY MC Burney's incision 1- grid iron incision( int. Oblique and transverse muscle splitting incision) 2- Rutherford Morrison incision Lan'z incision ( in gap of 4-6 weeks appendectomy) Lower middle line abdominal incision ( for perforated appendix) 3 ports 1- infraumblical 2- left iliac fossa 3supra pubic region STEPS • 1- locate appendix after peritoneum is open - base is at junction of three taenia coli • 2- ligate the appendicular Artery and remove mesoappendix • 3- clamp the base • 4- remove the appendix • NOTE! stump of appendix should be left not more than 4 -5 mm. COMPLICATION AFTER SURGERY • 1- haemorrhage • 2-wound/ surgical site infection (MC) • 3- ilio-hypogastric nerve injury • 4- portal pyemia • 5- pelvic abscess • 6- stump appendcitis Source • https://en.medicina.ru/clinical -c as e/differential -di agnosis -of-acute -appendicitis / • https://emedicine.medsc ape.com/ar ticle/773895 -differentia • https://radiopaedia.org/ • https://www.sciencedi rec t.c om/ • https://medlineplus .gov /lab -tes ts /appendici tis -tes ts / • Pre-pg.c om THANKYOU