Neuromuscular blocking Drug Non-depolarizing action Rapid onset (within one circulation time) Short duration, suitable for infusion Rapid metabolism to inactive products Antagonized by cholinesterase inhibitors Actions confined to the NMJ Not transferred across the placenta or blood-brain barrier No local or systemic side-effects Compatibility with other drugs and solutions Long shelf life without refrigeration Cheap Made by chemical synthesis Sterilizable Dose Onset of action Duration of action Method of elimination