INFECTION Presented by : Nitiakaliyani a/p Balasubramaniam LEARNING OUTCOMES: By end of the session, the student will be able to: 1. Define infection. 2. State the classification of infection. 3. Explain pathogenicity, virulence, invasiveness and colonization. 4. Discuss the stages of infectious process. 5. Identify the main sources of infection. INFECTION Definition: Invasion and multiplication of microorganism into the body, causing damage to tissues and diseases to host. INFECTION Disease producing microorganisms are called pathogens The ability of a microorganism to produce disease is called pathogenicity. The frequency with which a pathogens causes disease is called virulence INFECTION The ability of a pathogen to invade tissues are called invasiveness. The presence of microorganisms on the body surface (eg. skin, mouth, intestine) without causing disease in the person is called colonization. RECAP CLASSIFICATION OF INFECTIONS 1. 2. 3. 4. 5. 6. 7. 8. 9. Local Infection Systemic Infection Bacteremia Septicemia Acute Infections Chronic infections Nosocomial infections Cross- infections Iatrogenic infections CLASSIFICATION OF INFECTIONS 1. Local Infection A local infection is limited to the specific part of the body where the microorganisms remains. Exhibits redness, swelling and pain. Eg. pimples. CLASSIFICATION OF INFECTIONS 2. Systemic Infection Systemic infection is when the microorganisms spread and damage different parts of the body. Symptoms include fever, fatigue and headache CLASSIFICATION OF INFECTIONS 3. Bacteremia Bacteri means “bacteria” + Haima means “blood”. The presence of bacteria in the blood. CLASSIFICATION OF INFECTIONS 4. Septicemia Septi means “sepsis”. Widespread destruction of tissues due to absorption of disease causing bacteria or their toxins from the bloodstream. 5. Acute Infections Acute infections generally appear suddenly or last a short time. Eg. Chicken pox, cough and cold CLASSIFICATION OF INFECTIONS 6. Chronic infections It may occur slowly over a very long period and last months, years or lifetime. e.g. Cancer 7. Nosocomial (hospital-acquired) infections Noso means “disease”. Komeion means “take care of”. Define as any infection acquired during hospitalization. Common infections sites are urinary tract, respiratory tract, bloodstream and wounds 8. Cross- infections The transfer of infection from one patient to another in hospital. Example: MRSA (Methicillin-resistant Staphylococcus aurens) infections. CLASSIFICATION OF INFECTIONS 9. Iatrogenic infections Iatro means “the healer or doctor”. gennan means “produced by”. The direct result of diagnostic or therapeutic procedures. RECAP 1. What are the classification of infections ? • Local Infection • Systemic Infection • Bacteremia • Septicemia • Acute Infections • Chronic infections • Nosocomial infections • Cross- infections • Iatrogenic infections STAGES OF THE INFECTIOUS PROCESS Once a pathogen has gained entrance into the body, the course of infection progress through 4 stages: 1. Incubation period 2. Prodromal period 3. Period of illness 4. Convalescent period STAGES OF THE INFECTIOUS PROCESS STAGES OF THE INFECTIOUS PROCESS 1. Incubation period Is the time interval between entry of an infectious agent into the host and the onset of symptom. The infectious agent invades the tissues and begins to multiply to produce an infection. STAGES OF THE INFECTIOUS PROCESS 2. Prodromal period An early stage of a developing disease. During this period, the infectious agent continues to invade and multiply in the host. STAGES OF THE INFECTIOUS PROCESS 3. Period of illness The time during which the person experience symptoms of the particular disease eg. Headache, sore throat. RECAP What are the 4 stages of infectious process? 1. Incubation period 2. Prodromal period 3. Period of illness 4. Convalescent period MAIN SOURCES OF INFECTION Humans Environment Other animals and birds SUMMARY Infection is defined as the invasion of pathogenic microorganisms and their multiplication causing damage to tissues and diseases to the host. There are nine classification of infection. Infection process are consists of 4 stages. THANK YOU