NEUROPHYSIOLOGY CEREBELLUM Neurophysiology Ms. Chanda Chisunka • Located caudally to the cerebral cortex, the cerebellum contributes about 10% to the brain’s weight but contains more than half of all the neurons in the brain. • It plays a fundamental role in coordinating and finetuning movements initiated in other areas of the brain. • It adjusts the outputs of the pyramidal and extrapyramidal system. Any damage to the cerebellum translates in rougher movements as if these were improperly calculated • To achieve the desired coordination, the cerebellum uses the input information coming from the pyramidal and extrapyramidal system indicating the intended movement. • It also integrates the information gathered from muscle spindles throughout the body, from the visual system, from the vestibular system and many other receptors which indicate what movement is actually taking place. Functional divisions of the cerebellum Information from • Pyramidal • Extrapyramidal Compared to • Information from • Spindles • Vision • Vestibule • Other receptors • Corrected output Functional divisions of the cerebellum Spinocerebellum • Coordinates muscle tone and movement Vestibulocerebellum • Coordination of balance and eye movements Cerebrocerebellum • Coordinates planning movement of extremities Spinocerebellum • The spinocerebellum is located in the medial portion of the cerebellum, it collects information from the muscle and skin carried by the spinal cord. It also receives inputs from auditory, visual and vestibular systems. Spinocerebellum • The spinocerebellum processes all this information and sends efferent output through the deep cerebellar nuclei to the pyramidal and extrapyramidal system. The outputs are corrections or adjustments between the intended and actual movements. Modifying the movement itself and the muscle tone achieve these adjustments Vestibulocerebellum • The vestibulocerebellum is located in the flocculonodular lobe (posterior ventral area), it collects inputs from the visual and vestibular system and sends efferent output to the vestibular nuclei to regulate balance as well as head and eye movement. Cerebrocerebellum • The cerebrocerebellum is located in the lateral hemispheres of the cerebellum. Input comes from the area of the cerebral cortex controlling sensory and motor functions. • The output is directed back to the premotor area of the cerebral cortex with the information to execute specific movements of the extremities. Spinocerebellum • The spinocerebellum is located in the medial portion of the cerebellum, it collects information from the muscle and skin carried by the spinal cord. It also receives inputs from auditory, visual and vestibular systems. Spinocerebellum • The spinocerebellum processes all this information and sends efferent output through the deep cerebellar nuclei to the pyramidal and extrapyramidal system. The outputs are corrections or adjustments between the intended and actual movements. Modifying the movement itself and the muscle tone achieve these adjustments Cerebellar deficiencies • Wide-base gait Compensates imbalance • Ataxia Uncoordinated • Dysmetria Overshooting • Intention tremor Oscillating approach Cerebellar deficiencies • Past pointing Exaggerated movement • Dysdiadochokinesia Sequencing problems • Dysarthria Vocal sequence problems • Cerebellar nystagmus Eyeball oscillation • Hypotonia Lower peripheral muscle tone • END