Skin Integrity and Wounds Sandra S. Jones, MSN, RN, CNE 1 Types of Wound Healing Primary Secondary Tertiary 2 Primary Intention: The wounds’ dermal edges are re-approximated and held together e.g., with sutures, staples, steri-strips or surgical glue. This reduces tissue loss. Wound edges are well approximated. Wound Healing by Primary Intention 3 Secondary Intention: A wound that involves area of tissue loss; it is left open until it becomes filled by scar tissue. Doctors will leave the wound to heal naturally in these cases; but takes longer to heal and greater chance of infection Healing by Secondary Intention More common for wounds that have a rounder edge, cover uneven surfaces, or are on surfaces of the body where movement makes stitches or other closure methods impossible. Secondary wound healing relies on the body’s own healing mechanisms. 4 Tertiary wound healing, or healing by delayed primary closure, occurs when there is a need to delay the wound-closing process. Wound Healing by Tertiary Intention This could be necessary if a doctor fears that an infectious agent may be trapped in a wound by closing it. In these cases, the wound may be allowed to drain or wait for the effects of other therapies to take place before closing the wound. 5 Phases of Wound Healing 6 STOP THE BLEEDING! Reduced blood flow PHASES: Hemostasis (Day 1) Initial vasoconstriction (5-10 minutes); then vasodilation (persistent) ADP (Adenosine Diphosphate) leaks from damaged tissue, attracting platelets. Platelet aggregation initiates the clotting cascade- platelet plug is formed; bleeding is stopped Inflammation initiation 7 PREVENTS INFECTION, BEGINNING OF FRAMEWORK FOR NEW BLOOD VESSEL GROWTH PHASES: Inflammatory (Days 1-4) Increased vascular permeability Inflammatory cells enter wound– (Inflammatory cells = lymphocytes, neutrophils, monocytes) Secretion of cytokines and growth factors into the wound Activation of the migrating cells 8 Inflammatory Phase 9 PULLS THE WOUND CLOSED PHASES: Proliferative (Day 4-21) ) Fibroblasts lay a collagen scaffold Keratinocytes migrate over the scaffold M1 > M2 macrophage polarization Angiogenesis occurs 10 Proliferative Phase Re-epithelialization 11 Proliferative Phase 12 Proliferative Phase 13 FINAL PROPER TISSUE, SCAR IS ESTABLISHED PHASES: Remodeling/ Maturation (Day 21– 2 years) Macrophages recede Fibroblasts continue to remodel collagen in the scar, improving pliability and appearance Smaller vascular tissue aggregates into larger vessels There is a reduction of the scar 14 PHASES: Remodeling/ Maturation 15 During wound healing the body needs: Factors that Affect Wound Healing: Nutrition More calories Protein Fluid Vitamin A Vitamin C Zinc Copper Inadequate nutrition impede the normal processes that allow progression through stages of wound healing Malnutrition is related to decreased wound tensile strength and increased infection rates Serum Albumin proteins are biochemical indicators of malnutrition– most frequently measured. Prealbumin is the most accurate – gives more current nutritional status 16 Nutritional Support for Wound Healing 17 Factors that Affect Wound Healing: Tissue Perfusion Tissue Perfusion: Availability of oxygen to cells in the wound area is an important factor to the healing process. Oxygen plays a critical role in the formation of collagen, growth of new capillaries and the control of infection. Clinical interventions to maintain perfusion and oxygen supply include: Fluid volume assessments Pulmonary hygiene regimens Postoperative position changes Ambulation 18 Studies have shown that infection triggers the body’s immune response, causing inflammation and tissue damage, as well as slowing the healing process. Factors that Affect Wound Healing: Infection Bacteria can enter wounds and form biofilms. They release chemicals that prevent immune cells from killing these bacteria and delay wound healing. Fibroblast proliferation was depressed at the wound edges Small vessel angiogenesis was increased in areas of abscess formation, but larger vessels were commonly blocked by thrombus or distorted by inflamed tissue. Indicators of Wound Infection: Redness Swelling Purulent exudate Smell Pain Systemic illness 19 Factors that Affect Wound Healing: Aging Age-related differences in wound healing have been clearly documented. They have a slower healing process All phases of wound healing are affected Inflammatory response and proliferative stage are delayed or decreased Remodeling occurs, but to a lesser degree The collagen formed is qualitatively different Diseases that affect wound healing are more prevalent in the elderly and have a greater adverse effect than in the young 20 Factors that Affect Wound Healing: Psychosocial Impact of Wounds Psychological impact for patients with wounds can be significant Adverse psychological effects frequently occur when there are permanent changes in the body’s structure or function Anxiety, depression, and stress can adversely affect the wound healing process 21 Complications of Wound Healing: HEMORRHAGE Internal bleeding is considered a leading cause of trauma-associated mortality globally. If untreated, severe or chronic hemorrhaging might lead to organ failure, seizures, coma, external bleeding and eventually death. Wound hematoma, a collection of blood and clot in the wound, is a common wound complication and is usually caused by inadequate hemostasis. 22 Wound infection is the 2nd most common health-care associated infection Risk Factors: Complications of Wound Healing: INFECTION Hyperglycemia Smoking Untreated peripheral vascular disease Obesity Age Emergency surgery Signs and Symptoms of Wound Infection Erythema Increased amount of wound drainage Change in appearance of wound drainage (thick, color change, presence of odor) Periwound warmth, pain, or edema Increased temp and WBC count 23 Dehiscence: Unintentional reopening of a surgical wound, either internally or externally. Usually happens within 2 weeks of surgery and following abdominal or cardiothoracic procedures. Prevention of Dehiscence (Teaching to patient): Complications of Wound Healing: DEHISCENCE Don’t lift anything >10 pounds Be extremely cautious in the first 2 weeks of recovery – walk around to avoid blood clots or pneumonia (but don’t push for much more than this) Start slightly with rigorous physical activity at your own pace after 24 weeks After about 2 months, start pushing a little more, but listen to your body Treatment of Dehiscence: • Always report dehiscence to your surgeon • Cover the incision with sterile/clean dressing until you receive further instructions from surgeon. 24 Complications of Wound Healing: EVISCERATION Evisceration: A rare, but severe surgical complication where the surgical incision opens (dehiscence) and abdominal organs then protrude or come out of the incision (evisceration) Treatment of Evisceration: Cover the wound with sterile dressing moistened with warm sterile saline Doctor will probably order antibiotics and pain medication Surgery will be necessary to remove any dead tissue and repair the wound 25 Old terminology = ‘Pressure ulcer’, ‘bed sore’, or ‘decubitus ulcer’ Pressure Injury Pressure Injury: Localized damage to the skin and/or underlying soft tissue usually over a bony prominence or related to a medical or other device. The injury may present as intact or an open ulcer and may be painful The injury occurs as a result of intense and/or prolonged pressure or pressure in combination with shear. (Edsburg et al., 2016) 95% of all pressure ulcers are preventable! 26 Impaired Sensory Perception – Unable to feel when a part of body undergoes increased, prolonged pressure or pain Risk Factors for Pressure Injury Formation Decreased Mobility – Unable to turn themselves independently (Spinal cord injury) Alteration in Level of Consciousness – Those who are comatose, confused, or disoriented, inability to verbalize Shear/Friction – when HOB is elevated Moisture – Presence and duration of moisture on the skin increases the risk of pressure injury. Moisture reduces the resistance of the skin to other physical factors such as pressure, friction or shear 27 SHEAR AND FRICTION Risk Factors for Pressure Injury Formation Shear Friction 28 (coccyx) Areas High Risk for Pressure Injury Formation (trochanter) Bony Prominences (areas where bones are close to the skin surface) In bed, bony prominences can be padded with foam or pillows to help keep them free of pressure and skin-to-skin contact 29 Pressure injury prevention and treatment products are readily available. At a minimum, this includes: - Pressure Injury Prevention Skin moisture barrier products Appropriate incontinence containment products/bedding Pressure redistribution mattresses Heel offloading devices Pillows or wedges for repositioning Repositioning slings/sheets to use with ceiling lifts 30 Staging of Pressure Injury STAGE I: Nonblanchable erythema of intact skin 31 Staging of Pressure Injury STAGE 2: Partial-thickness with exposed dermis Skin loss involving the epidermis and/or dermis. The ulcer is superficial and presents clinically as an abrasion, blister or shallow crater. 32 Staging of Pressure Injury STAGE 3: Full-thickness skin loss Skin loss involving damage or necrosis of subcutaneous tissue that may extend down to, but not through, the underlying fascia. 33 Staging of Pressure Injury STAGE 4: Full-thickness skin and tissue loss skin loss with extensive destruction, tissue necrosis or damage to muscle, bone, or supporting structures (for example tendon or joint capsule). 34 Staging of Pressure Injury Unstageable Obscured fullthickness skin and tissue loss Necrotic tissue must be removed before a wound can be accurately staged If the initial assessment is of a granulating wound bed, it is not clinically accurate to stage the wound due to not seeing the depth of tissue injury ageable Do not reverse stage. This is clinically inaccurate b/c this implies deeper tissue layers heal by regeneration instead of granulation formation. 35 Staging of Pressure Injury Deep Tissue Pressure Injury: Persistent nonblanchable deep red, maroon or purple discoloration. Deep-Tissue Pressure Injury 36 ASSESSMENT: • Assess the patient’s perception of proposed wound treatment Assess at initiation of care and at least once/shift Use visual and tactile inspection NURSING PROCESS Look at any medical devices that may apply pressure to the skin Pay particular attention to bony prominences, next to or around medical devices, under casts, traction, braces, etc. Be alert for hyperemia (increased blood flow) Determine if wound is causing pain – pre-medicate before dressing change 37 ASSESSMENT: • Wound assessment: • Wound Location • Stage/Classification of Wound -- Assess the type of tissue in the wound base (viable vs. nonviable) NURSING PROCESS • Granulation tissue – red, moist tissue composed of new blood vessels, the presence of which indicates progression toward healing • Slough – Soft yellow or white tissue of a stringy consistency attached to the wound bed. • Eschar – black, brown, tan or necrotic tissue • Measure the wound (length, width, and depth) • Presence of undermining, sinus tracts, or tunneling • Exudate (Amount, color, consistency, odor of drainage – excessive exudate indicates infection • Wound pain • Examine the skin around the wound (Periwound) for redness, warmth, signs of maceration 38 Granulation Tissue 39 Slough 40 Eschar 41 Wound Measurement: First measure length: Widest point (head to toe) Then measure width: Widest point (laterally) Depth: Insert a sterile cotton-tip applicator in the deepest part of the wound, marking the skin level with your finger. 42 Undermining: Destruction of the underlying tissue surrounding some or all of the wound margins; may extend in one or many directions underneath the wound edges. Tunneling: A narrow opening or passageway that can extend in any direction through soft tissue and result in dead space with potential of abscess formation. Also known as sinus tract 43 ASSESSMENT: • Wound Cultures – Collection of specimen of purulent or suspicious-looking drainage is present. NURSING PROCESS •Never collect the specimen from old drainage •Clean the wound first with normal saline to remove skin flora •Gold standard of wound culture is wound biopsy – must be done by HCP or wound care specialist 44 ASSESSMENT: NURSING PROCESS • Maceration: softening and breaking down of skin resulting from prolonged exposure to moisture 45 PROBLEM STATEMENT: Impaired Skin Integrity Risk for Impaired Skin Integrity NURSING PROCESS Additional Nursing Diagnoses related to Impaired Skin Integrity Risk for Infection Acute or Chronic Pain Impaired Mobility Impaired Peripheral Tissue Perfusion 46 PLANNING (Goals and Outcomes): An appropriate GOAL for a patient with a wound: NURSING PROCESS Wound will progress toward healing within a twoweek period AEB: Increase in percentage of granulation tissue No further skin breakdown Increase in caloric intake by 10% 47 IMPLEMENTATION HEALTH PROMOTION: NURSING PROCESS Nutrition – Cleveland Clinic (2017) recommends: • Protein (5-8 servings daily • Whole grains (5 servings daily) • Vegetables (2 servings daily) • Fruit (3 servings daily) • Dairy (3 servings daily) 48 IMPLEMENTATION HEALTH PROMOTION: NURSING PROCESS Prevention of Pressure Injuries – Three major areas of nursing interventions for prevention of pressure injury: • Skin care and management of incontinence • Mechanical loading and support devices • Education 49 IMPLEMENTATION Topical Skin Care and Incontinence Maintenance: NURSING PROCESS • Use cleaners with nonionic surfactants that are gentle to the skin • Make sure skin is completely dry • Apply moisturizer, but don’t oversaturate 50 Moisture Balance Protective Ointment which is petroleum-based, provides excellent barrier that seals out excess moisture in the case of diarrhea. It contains emollients to moisturize and is non-sensitizing and fragrance free. 51 IMPLEMENTATION Topical Skin Care and Incontinence Maintenance: NURSING PROCESS • Control, contain or correct incontinence, perspiration or wound drainage • Diarrhea – gently clean the area, dry and apply thick layer of moisture barrier 52 IMPLEMENTATION Positioning • Repositioning (turning at least every 2 hours—some patients require more often) NURSING PROCESS • Reduces or relieves pressure at the interface between bony prominence and support surface (bed or chair) • Limits the amount of time the tissue is exposed to pressure • “Rule of 30” • HOB elevated no more than 30° • 30° lateral incline 53 NURSING PROCESS • “Repositioning patients at risk for pressure ulcers every three hours at night using the 30° tilt reduces the incidence of pressure ulcers more than usual care.” • Citation: Moore, et al. (2012) 54 IMPLEMENTATION Positioning • “Floating Heels” – Patient’s heels should be positioned in such a way as to remove all contact between the heel and the bed NURSING PROCESS 55 IMPLEMENTATION Positioning Tips: • To prevent shear and friction injuries, use a transfer device to lift rather than drag the patient when changing positions. NURSING PROCESS • High-risk patients who can sit in chairs should be limited to 2 hours or less; in addition, teach the patient to shift their weight every 15 minutes; use air, foam, or gel cushion 56 IMPLEMENTATION Support Surfaces NURSING PROCESS • “Specialized devices for pressure redistribution designed for management of tissue loads, microclimate, and/or other therapeutic functions (i.e. any mattress, integrated bed system, mattress replacement, overly, seat cushion.” (EPUAP, NPLIAP 2019a) 57 IMPLEMENTATION Support Surfaces • Category One • Static overlays and mattresses • Foam, air, gel NURSING PROCESS • Category Two • Alternating pressure and air flotation • Category Three • Air fluidized • Low air loss bed/mattress 58 IMPLEMENTATION Acute Care • Acute wounds require close monitoring (every 4-8 hrs.) • Chronic wound assessment is less frequently • Wound Management: NURSING PROCESS • Goal is – maintenance of a physiological local wound environment. • • • • • • • • Prevent/Manage Infection Clean the wound Remove nonviable tissue Maintain wound in a moist environment Eliminate dead space Control odor Eliminate or minimize pain Protect the wound and periwound skin 59 IMPLEMENTATION Wound Management • To help prevent infection, clean wound with noncytotoxic wound cleanser NURSING PROCESS • Wound Irrigation – cleans and debrides necrotic tissue (use 19 gauge catheter with 35 mL syringe – delivers saline at 8 psi) 60 IMPLEMENTATION Wound Management - Debridement • Debridement is the removal of nonviable, necrotic tissue • Methods of Debridement: NURSING PROCESS • • • • Autolytic Mechanical Chemical Sharp/Surgical 61 Autolytic Debridement: Removal of dead tissue via lysis or necrotic tissue by WBCs and natural enzymes of the body • Accomplished with specialized dressing • If wound bed is dry, use a dressing that adds moisture • If there is excessive exudate, use a dressing that absorbs the excessive moisture Films for Autolytic Debridement Hydrogel Dressings for Autolytic Debridement 62 Chemical Debridement: Use of topical enzyme preparations that induce changes in the substrate, resulting in the breakdown of necrotic tissue (Dakin’s Solution, or sterile maggots) Dakin’s Solution for Chemical Debridement Collagenase – Enzymatic Debridement 63 Debridement with Sterile Maggots 64 Sharp/Surgical Debridement: Removal of devitalized tissue with a scalpel, scissors or other sharp instrument. Physicians, or specially trained Wound Care Nurse are allowed to perform this task. 65 Mechanical Debridement: Involves high-pressure wound irrigation, pulsatile high-pressure lavage, and whirlpools. 66 IMPLEMENTATION Wound Management: Dressings Purposes of Dressings • Protects a wound from microorganism contamination • Aids in hemostasis NURSING PROCESS • Promotes healing by absorbing drainage and debriding wound • Supports or splints a wound site • Promotes thermal insulation of a wound surface • Provides a moist environment 67 IMPLEMENTATION Wound Management: Dressings for Pressure Injuries NURSING PROCESS Type of Dressing is based on the stage of the pressure injury, types of tissue in the wound, and the function of the dressing Gauze sponges (oldest and most common) • Absorbent and wick away wound exudate • Gauze can be saturated with solutions to clean and pack a wound 68 IMPLEMENTATION Wound Management: Packing a Wound • Be aware of the reason for packing the wound (debridement or absorbing exudate) NURSING PROCESS • Check physician’s order (gauze, solution, frequency) • Measure wound • Technique is usually “clean” (not sterile) – but use sterile dressing supplies • Saturate gauze with solution, wring out, unfold and lightly pack into wound • Cover wound and packed gauze with a secondary dressing 69 EVALUATION: The outcomes selected for the patient in the plan of care are the milestones you hope to achieve to meet the goals of care. NURSING PROCESS GOAL Wound will progress toward healing within a two-week period AEB: OUTCOMES Increase in percentage of granulation tissue No further skin breakdown Increase in caloric intake by 10% 70 THE END 71