1. Development of the toxic blood levels of a drug? - Prolonged half-life 2. Completely metabolized drug by the first pass effect, the drug must be administered: - Higher doses?? Frequent usage 3. Stressed induced catecholamines released from the adrenal medulla may result in: - peripheral vasoconstriction 4. Improved function of the heart and brain during a stress response results from: - Peripheral vasodilation 5. Adverse effect of the glucocorticoids? - Osteoporosis 6. Localize and contain foregin material during inflammatory response? - Fibrinogen 7. Expected finding in a patient with chronic inflammation? - Fibroblasts 8. The nurse is caring for a client who has a surgical wound on the abdomen that has dehisced and contains a creamy exudate and small area of deep pink granulation tissue. As a nurse caring for this client, you would expect the wound to help by: - Delayed primary intention healing 9. A patient with massive trauma to the leg has extensive muscle damage and wide, irregular wound edges, which is true about the healing of this wound? - Most of the skin and skeletal muscle will be replaced by connective tissue 10. Most effective mechanism to help bring a patient’s body temperature up to a new set point of 39C? - Generalized shivering 11. When do clinical signs of infection occur? - When the microbial colony is large enough to damage the host 12. The mechanism of action of aspirin as an analgesic us to: - Inhibit the production of prostaglandins 13. An accurate definition of transduction - The detection of painful stimuli by sensory receptors 14. Antidote for warfarin overdose? - Vitamin K 15. Hydrostatic pneumonia is more likely to develop in the immobilized person? explain 3 possible causes of pulmonary edema - 1. may be caused by left side CHF, - 2. increased hydrostatic pressure in the pulmonary capillaries, - 3. kidney disease, - 4.inhlalation of irritant gases of pathogen causing inflammation and - 5. increased capillary permeability 16. Asthma - Reversible airway obstruction 17. Side effects of the anticholinergic medication? - Urinary retention and constipation 18.