. Hanoi University of Science and Technology School of Foreign Languages MARKING SHEET FOR LONGER ESSAYS Student’s name: Class: Essay’s title: Max. Score (/100) 10 40 5 5 30 10 MARKING CRITERIA Grade Poor (0-39); Adaquate (40-54); Satisfactory (55-69); Very Good (7084); Excellent (85-100) Introduction: • Well-developed introduction engages the reader and creates interest; • Introduction clearly states the objectives of the paper. Body: • relevant and appropriate content; • Fluent and logical progression of ideas with a clear and well-organized structure; • use of existing literatures to support the objectives of the paper; presenting information collected from a variety of quality electronic and print sources, including appropriate licensed databases; • showing the author’s critical perspective in reading and reporting the works of others, rather than simply a compilation of facts and summaries of previous studies. Conclusion: • Effectively wraps up and goes beyond summarizing main ideas; • Conclusion is logical, discusses the implications of the paper, and demonstrates independent thought. Format: • Inclusion of all necessary sections of a longer essay: Cover page, content page (if there are headings and numbers in the paper), title, introduction, body, conclusion, and references • Presentation of essay sections. • Use of font, size, line spacing, etc. as required (Times New Roman, font size 12/Arial size 10; double spacing) • Length of the paper (1,200-1,500 words) Use of English language: • Paragraphing • Coherence and cohesion • Grammatical range and accuracy • Lexical variety • Range of sentence structures (simple, compound, complex) • Spelling and punctuation Citation and referencing (using APA referencing system): • Observation of citation rules: correctness and consistency (80%) • Producing a correct reference list (20%) 100 Assessor: (Signature and Full name) Date: 1 TABLES OF CONTENTS Introduction ........................................................................................................... 3 1. The impacts of funding medical research into disease .................................. 3 1.1 Medical advancement .................................................................................. 3 1.2 Economic growth.......................................................................................... 4 1.3 Socio-political development......................................................................... 5 2. Concerns over medical research fund into disease ........................................ 6 Conclusion .............................................................................................................. 6 REFERENCES ...................................................................................................... 6 2 FUNDING MEDICAL RESEARCH INTO DISEASE: LOW-RISK INVESTMENT FOR LONG-TERM PROFIT Introduction Over the past few decades, various deadly infectious diseases caused by new strains or evolved viruses have attacked human life continually with the succession of SARS, MERS, ZIKA, EBOLA, and other perilous influenza illness. Thus, the priority concern for centuries is still “How the era of epidemics comes to an end?”. The bacteria that will trigger the world's next plague are already among us, and the illness breakout is unpredictable. Conversely, these lurking pathogens will likely follow the path that previous contagions blazed. The critical lesson learned form past experiences is that we cannot continue to do the same as we have done before; moreover, the preparation for continuous funding support and other intervention measures are imperative for the next pandemics. This essay is dedicated to emphasizing the great importance of government’s funding medical research into disease. To achieve that end, the essay first discusses the impacts of funding research into disease on three different aspects: medical advancement, economic growth, socio-political development and then some concerns over issue. 1. The impacts of funding medical research into disease 1.1 Medical advancement First of all, funding research into disease has led to substantial discoveries, the new therapies’ development, and a remarkable improvement in medicine. Based on the goal of finding thorough disease prevention and highly effective treatment, a series of clinical research have been conducted annually. For example, during the period 1974 – 1922, more than 9,000 beast cancer patients from across The United States participated in clinical research in the University of San Antonio. Researchers had analysed these databases meticulously and finally, they identified the HER-2 oncogene as “a significant predictor of both overall survival and 3 time to relapse in patients with breast cancer” (Slamon et al., 1987). Many other results from medical research can provide important information about disease trends, risks factors, outcomes of treatment or public health interventions. This information has indicated not only the efficacy but also the adverse effects of medical interventions such as new drugs or vaccines. Funding medical research on new diseases have also paved the way for a more radical and thorough preparation for the next pandemic. In-depth medical study conducted in 2020 demonstrated that the SARS-CoV in 2003 and the SAR-CoV-2 in 2019 had structural and replication similarities, as well as host cell infection receptor recognition and proteolytic activation (Rossi et al., 2020). According to Jia and Wu (2020), between 2007 and 2009, a series of clinical studies of SARS vaccinations shown some effectiveness, but the experiments were halted due to a lack of ongoing financing. Consequently, investing significantly and constantly in the development of countermeasures to control emerging viruses will keep us from "dropping the ball" in related research after pandemics. Furthermore, the studies on disease trends and possibilities of infection at the national levels will provide enough diagnostics, vaccines, and drugs, as well as infrastructure for any potential emerging epidemic or pandemic. 1.2 Economic growth The impact of funding medical research into disease in the healthcare is widely understood, however an equally important but less well-acclaimed relationship exists between improvements in health and the growth of an economy. Thanks to advances in epidemiological research, both governments and firms that hold medical research may benefit handsomely from the sale of vaccinations and treatments. As Michael and Manas (2021) reported, “The sales of the COVID-19 vaccine are likely to reach $36 billion in 2021 and $29 billion in 2022, above analyst expectations in both years.” Moreover, “The American pharmaceutical company said it is looking to secure new vaccination agreements with governments, which may boost sales 4 even more next year.”. Consequently, not only does it increase economic potential in the fields of medicine and pharmaceuticals, but it may also help the government save money on vaccine purchases. Besides business benefits, investing more capital in disease research have a great ability in limiting the risk of economic crisis caused by the epidemic. In 2019, the new coronavirus (SARS-CoV-2) leads to severe lung infection and unique pneumonia disease, namely the COVID-19 that severely destroyed national economy. Its stringers a global crisis in health and slowing international trade and commerce due to strict measures for quarantine. However, these damages can be lessened if we go ahead and stay ahead. The goal of insight medical research into disease is the improvement in human health and longevity which will lead to augment of national economy. 1.3 Socio-political development Additionally, funding medical research into disease is expected to bring about longterm profit in socio-political development. Specifically, owning in-depth disease research enables one country to increase political advantages in the region. For instance, France has recognised as the second contributor in ensuring access to medicines globally through its contribution to the Global Fund to Fight HIV/AIDS, tuberculosis, and malaria (“Paris to serve as host city for World Malaria Day 2019,” 2019). Aside from the political benefits, vaccine funds from infectious illness research contribute to community immunity, which has a significant influence on social security. Covid vaccination is offered at no cost to recipients in the United States because of Pfizer's research (“Covid-19 vaccines are free to the public,” 2021). Finally, social distancing and self-quarantine will never be a serious issue. Medicine is critical in the fight against illness, and this is especially true when new illnesses emerge to endanger human health. Nonetheless, there are also some reservations about this matter. 5 2. Concerns over medical research fund into disease Is this too expensive for a preparation and are people worrying too much for an unpredictable future? In fact, what we have paid for directly facing with continued infectious disease including SARS, MERS, ZIKA, EBOLA is uncountable, and we should stay ahead of the game to minimum unnecessary damages from it. Moreover, some infectious pathogens often have the same genotype so that we can easily predict the disease trends and risk factors. Developments for medicine are never superfluous since the more the environment degrade, the stranger disease appear, and we must find the solution before doomsday disaster. Conclusion In a nutshell, it is obvious that medical research fund has contributions not only in Politics, Society, Economics but also Medicine and it gradually becomes an urgent preparation for the future prevention to control infectious and non-communicable diseases. Therefore, it is high time for government to make urgent, radical, and fundamental change for next pandemic by building medical research fund into disease. (Total: 1067 words) REFERENCES (1) Covid-19 vaccines are free to the public. (2021, November 3). CDC. Retrieved from: https://www.cdc.gov/coronavirus/2019-ncov/vaccines/no-cost.html (2) Hegde, D and D C Mowery (2008), "Politics and funding in the US public biomedical R&D system", Science 322(5909): 1797–1798. Retrieved from: https://voxeu.org/article/when-government-increases-funding-research-disease-others-spendless (3) Michael, E & Manas, M. (2021, November 3). Pfizer expects 2021, 2022 COVID-19 vaccine sales to total at least $65 bln. Reuters. Retrieved from: https://www.reuters.com/business/healthcare-pharmaceuticals/pfizer-raises-covid-19-vaccinesales-forecast-36-billion-2021-11-02/ (4) Paris to serve as host city for World Malaria Day 2019. (2019, March 18). Ministry of Health. 6 Retrieved from: http://www.impe-qn.org.vn/impe-qn/en/portal/InfoDetail.jsp?area=58&cat=1075&ID=1286 (5) Rossi, G.A., Sacco, O., Machino, E. et al. (2020). Differences and similarities between SARSCoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection, 48(665–669). Retrieved from: https://link.springer.com/article/10.1007/s15010-020-01486-5 (6) Slamon , J. K et al. (1987). Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neu Oncogene. Science, 237(4785). Retrieved from: https://www.science.org/doi/10.1126/science.3798106 7