Student name:__________ 1) _________blank are glycoprotein spikes that protrude from the outer surface of the viral envelope. Question Details Bloom's : 1. Remember Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 2) Icosahedral viruses are constructed from ring- or knob-shaped units called_________blank. Question Details Bloom's : 1. Remember Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 3) Viruses that are polyhedrons with 20 sides are said to have_________blank symmetry. Question Details Bloom's : 1. Remember Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02d Describe the types of capsid symmetry Accessibility : Keyboard Navigation Gradable : automatic Version 1 1 4) Some viruses cause abnormal growth of cells rather than destruction. This is called_________blank. Question Details Bloom's : 2. Understand Section : 06.04 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.04c Differentiate among the types of viral infections of eukaryotic cells Accessibility : Keyboard Navigation Gradable : automatic 5) Microscopic or macroscopic degenerative changes or abnormalities in infected host cells and tissues are called_________blank_________blank. Question Details Bloom's : 2. Understand Section : 06.04 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.04c Differentiate among the types of viral infections of eukaryotic cells Accessibility : Keyboard Navigation Gradable : automatic 6) Localized areas of destruction occurring on plants that have been infected by a virus are referred to as_________blank lesions. Version 1 2 Question Details Bloom's : 1. Remember Section : 06.04 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.04c Differentiate among the types of viral infections of eukaryotic cells Accessibility : Keyboard Navigation Gradable : automatic 7) Viruses can infect all known cell types. Specifically, the viruses that infect bacterial cells are called_________blank. Question Details Bloom's : 1. Remember Section : 06.01 Topic : Bacteriophage Cycles ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.01a Define the terms virology, bacteriophage, and phage Accessibility : Keyboard Navigation Gradable : automatic 8) Which isnot true of viruses? A) They can exist in an intracellular or extracellular phase. B) They infect animal and plant cells only. C) They can be observed with an electron microscope. D) They are acellular. E) They replicate only inside host cells. Version 1 3 Question Details Bloom's : 2. Understand Section : 06.01 Topic : General Viral Properties ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.01a Define the terms virology, bacteriophage, and phage Accessibility : Keyboard Navigation Gradable : automatic 9) Which of the following is true of viruses in the extracellular phase? A) They possess many different enzymes. B) They can reproduce independently of living cells but only at a slow rate. C) They behave as a macromolecular complex and are no more alive than are ribosomes. D) They possess many different enzymes and they can reproduce independently of living cells but only at a slow rate. Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viruses ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 10) A complete virus particle is called a_________blank. A) capsid B) nucleocapsid C) virion D) cell Version 1 4 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 11) The nucleic acids carried by viruses usually consist of_________blank. A) DNA B) RNA C) either DNA or RNA D) both DNA and RNA simultaneously Question Details Bloom's : 1. Remember Section : 06.02 Topic : Viral Structure ASM Topic : Module 04 Information Flow and Genetics ASM Objective : 04.04 The synthesis of viral genetic material and proteins is dependent on host cells Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 12) Which of the following isnot true of viruses? A) Viruses are acellular. B) Viruses consist of one or more molecules of DNA or RNA enclosed in a coat of protein and sometimes in other more complex layers. C) Viruses can existin two phases: intracellular and extracellular. D) Viruses replicate by binary fission. Version 1 5 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Replication ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.03a Describe the five steps common to the life cycles of viruses Accessibility : Keyboard Navigation Gradable : automatic 13) Virus morphology does not include which of the following characteristics? A) Size B) Shape C) Presence or absence of an envelope D) Host range Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 14) The simplest viruses consist of_________blank. A) RNA only B) protein only C) RNA or DNA in a protein coat D) RNA or DNA in a protein coat covered with a lipid envelope E) RNA, DNA, and enzymes in a protein coat with a lipid envelope Version 1 6 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 15) Viral capsid protein subunits are called_________blank. A) auxomers B) elastomers C) protomers D) viromers Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 16) In an enveloped virus, the part of the virus including the nucleic acid genome and the surrounding protein coat but not the envelope is called the_________blank. A) capsid B) nucleocapsid C) matrix D) virion Version 1 7 Question Details Bloom's : 1. Remember Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02c Distinguish enveloped viruses from nonenveloped viruses Accessibility : Keyboard Navigation Gradable : automatic 17) Some complex viruses have icosahedral symmetry in the head region and helical symmetry in the tail. Overall, these viruses are said to have_________blank symmetry. A) bilateral B) binal C) complex D) radial Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02d Describe the types of capsid symmetry Accessibility : Keyboard Navigation Gradable : automatic 18) Glycoprotein spikes protruding from the outer surface of viral envelopes function as_________blank. A) toxins B) factors that bind to host cells C) cell lysis factors D) factors needed for site-specific recombination Version 1 8 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 19) A_________blank genome exists as several separate, nonidentical molecules that may be packaged together or separately. A) diploid B) segmented C) polyploid D) fractionated Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 20) Many of the enzymes found in virus particles are_________blank. A) required for viral attachment to host cells B) involved in viral entry into host cells C) involved in the replication of viral nucleic acid D) All of the choices are correct. Version 1 9 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Replication ASM Topic : Module 03 Metabolic Pathways ASM Objective : 03.03 The survival and growth of any microorganism in a given environment depends on Learning Outcome : 06.03a Describe the five steps common to the life cycles of viruses Accessibility : Keyboard Navigation Gradable : automatic 21) Which of the following is/arenot true about viral envelopes? A) The envelope proteins are virus-specific. B) The envelope lipids and carbohydrates are derived from the host. C) They are typicallipid monolayers with embedded viral proteins. D) The envelope proteins are virus-specific and the envelope lipids and carbohydrates are derived from the host. Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02c Distinguish enveloped viruses from nonenveloped viruses Accessibility : Keyboard Navigation Gradable : automatic 22) Viral envelopes are composed of_________blank. A) proteins B) lipids C) carbohydrates D) All of the choices are correct. Version 1 10 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02c Distinguish enveloped viruses from nonenveloped viruses Accessibility : Keyboard Navigation Gradable : automatic 23) Two major types of symmetry found in viruses include_________blank. A) icosahedral and radial B) icosahedral and helical C) helical and radial D) radial and bilateral Question Details Bloom's : 1. Remember Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02d Describe the types of capsid symmetry Accessibility : Keyboard Navigation Gradable : automatic 24) The function of the viral protein coat is to_________blank. A) protect the viral genetic material B) aid in the transfer of the viral genetic material between host cells C) elicit the production of protective antibodies D) protect the viral genetic material and aid in the transfer of the viral genetic material between host cells Version 1 11 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 25) The protein coat surrounding the viral genome is called the_________blank. A) capsule B) capsid C) matrix D) envelope Question Details Bloom's : 1. Remember Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 26) Which of the following is true of a viral DNA genome? A) It uses the samefour nitrogenous bases found in prokaryotic and eukaryotic DNA. B) It may have thenormal bases found in prokaryotic and eukaryotic DNA, or it may have one ormore unusual bases. C) It is usually composed of unusual bases unique to viruses. D) Viruses use only RNA for their genome. Version 1 12 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 27) Virion size ranges from_________blank. A) 1–40 nm B) 10–400 nm C) 600–1,000 nm D) 1,000–10,000 nm Question Details Bloom's : 1. Remember Section : 06.02 Topic : General Viral Properties ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02a State the size range of virions Accessibility : Keyboard Navigation Gradable : automatic 28) Viral capsids are generally constructed without any outside aid once the subunits have been synthesized. This process is called_________blank. A) facilitated assembly B) self-assembly C) spontaneous maturation D) self-maturation Version 1 13 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Replication ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.03a Describe the five steps common to the life cycles of viruses Accessibility : Keyboard Navigation Gradable : automatic 29) In which of the following stages of the viral infectious cycle do enveloped viruses usually acquire their envelopes? A) Penetration B) Component biosynthesis C) Assembly D) Release Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Replication ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03c Describe the two most common methods for virion release from a host cell Accessibility : Keyboard Navigation Gradable : automatic 30) Most enveloped viruses use the host_________blank membrane as their envelope source. A) plasma B) nuclear C) mitochondrial D) None of these choices are correct. Version 1 14 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02c Distinguish enveloped viruses from nonenveloped viruses Accessibility : Keyboard Navigation Gradable : automatic 31) Poliovirus receptors are found_________blank. A) in cells of all tissues B) in the spinal cord anterior horn cells only C) in the nasopharynx, gut, and spinal cord anterior horn cells D) in gut cells only Question Details Bloom's : 3. Apply Section : 06.03 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 32) Nonenveloped viruses most often gain access to eukaryotic host cells by_________blank. A) fusion with the host cell plasma membrane followed by entrance of the nucleocapsid into the cytoplasm B) endocytosis C) pinocytosis D) nucleic acid injection through the plasma membrane Version 1 15 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.02c Distinguish enveloped viruses from nonenveloped viruses Accessibility : Keyboard Navigation Gradable : automatic 33) Which of the following represent(s) the way(s) in which enveloped viruses acquire their envelopes? A) Budding through the plasma membrane. B) Budding through internal cellular membranes. C) Viral enzymes are responsible for production of the envelope. D) Some viruses bud through the plasma membrane while others bud through internal cellular membranes. Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Infections ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.03c Describe the two most common methods for virion release from a host cell Accessibility : Keyboard Navigation Gradable : automatic 34) Animal viruses have been cultivated in_________blank. A) suitable host animals B) embryonated eggs C) tissue cultures (monolayers of animal cells) D) All of the choices are correct. Version 1 16 Question Details Bloom's : 2. Understand Section : 06.05 Topic : Viruses ASM Topic : Module 08 Microbiology Laboratory Skills ASM Objective : 08.02 Use pure culture and selective techniques to enrich for and isolate microorgani Learning Outcome : 06.05a List the approaches used to cultivate viruses, noting which types of viruse Accessibility : Keyboard Navigation Gradable : automatic 35) Which of the following can be used to cultivate plant viruses? A) Cultures of separated plant cells B) Whole plants C) Plant protoplast cultures D) All of the choices are correct. Question Details Bloom's : 2. Understand Section : 06.05 Topic : Viruses ASM Topic : Module 08 Microbiology Laboratory Skills ASM Objective : 08.02 Use pure culture and selective techniques to enrich for and isolate microorgani Learning Outcome : 06.05a List the approaches used to cultivate viruses, noting which types of viruse Accessibility : Keyboard Navigation Gradable : automatic 36) 0.2 mls of a 10-4 dilution of a virus preparation yields 90 plaques. What is the number of plaque-forming units (PFUs) per ml in the undiluted virus preparation? A) 9.0 × 105 B) 4.5 × 106 C) 4.5 × 107 D) 9.0 × 108 Version 1 17 Question Details Bloom's : 4. Analyze Section : 06.05 Topic : Viruses ASM Topic : Module 08 Microbiology Laboratory Skills ASM Objective : 08.04 Estimate the number of microorganisms in a sample (using, for example, direct c Accessibility : Keyboard Navigation Learning Outcome : 06.05b Define plaque-forming unit and explain its role in the quantification of vi Gradable : automatic 37) A _________blank assay is most useful for determining the viability of a viral preparation. A) direct (electron microscopic) count B) hemagglutination C) plaque D) PCR Question Details Bloom's : 4. Analyze Section : 06.05 Topic : Viral Replication ASM Topic : Module 08 Microbiology Laboratory Skills ASM Objective : 08.04 Estimate the number of microorganisms in a sample (using, for example, direct c Accessibility : Keyboard Navigation Learning Outcome : 06.05b Define plaque-forming unit and explain its role in the quantification of vi Gradable : automatic 38) Which of the following isnot a mechanism by which viruses cause cancer in eukaryotic animal cells? Version 1 18 A) They carry a cancer-causing gene into the cell. B) They encodeproteins that bind to and inactivate host cell proteins known as tumorsuppressor proteins. C) They produce defective interfering particles. D) An expression of viral proteins results in abnormal expression of genes that regulate cell growth and reproduction. Question Details Bloom's : 3. Apply Section : 06.04 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.04c Differentiate among the types of viral infections of eukaryotic cells Accessibility : Keyboard Navigation Gradable : automatic 39) Which of the following isnot true of viroids? A) Viroids are small circular ssRNA molecules. B) Viroids have no protein capsids. C) Viroid RNA does not serve as mRNA nor does it direct the synthesis of mRNA. D) Extracellular viroids have a lipid bilayer envelope. Question Details Bloom's : 2. Understand Section : 06.06 Topic : Viral Classification ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.06a Describe the structure of a viroid and discuss the practical importance of Accessibility : Keyboard Navigation Gradable : automatic 40) Viroids are of economic significance because they cause disease in_________blank. Version 1 19 A) plants B) animals C) humans D) All of the choices are correct. Question Details Bloom's : 3. Apply Section : 06.06 Topic : Viruses ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.06a Describe the structure of a viroid and discuss the practical importance of Accessibility : Keyboard Navigation Gradable : automatic 41) Viroids are_________blank. A) proteins that may infect man and other animals causing spongiform encephalopathy B) a class of so-called slow viruses C) a new class of small single-stranded DNA viruses that infect some animals D) short infectious single-stranded RNAs that can infect some plants Question Details Bloom's : 1. Remember Section : 06.06 Topic : Viral Classification ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.06a Describe the structure of a viroid and discuss the practical importance of Accessibility : Keyboard Navigation Gradable : automatic 42) Prions are of significance because they cause infections of_________blank. Version 1 20 A) domestic animals and humans B) plants C) fungi D) prokaryotes Question Details Bloom's : 1. Remember Topic : Microbial World ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07b List characteristics common to all animal diseases caused by prions Accessibility : Keyboard Navigation Gradable : automatic 43) Which of the following diseases is (are) caused by prions? A) Scrapie B) Mad cow disease C) Kuru and Creutzfeldt-Jakob Disease D) All of the choices are correct. Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07c Name at least two human diseases caused by prions Accessibility : Keyboard Navigation Gradable : automatic 44) Which virion release process is most often used by enveloped viruses? Version 1 21 A) Lysis B) Facilitated diffusion C) Budding D) Diffusion through a channel protein Question Details Bloom's : 4. Analyze Section : 06.03 Topic : Viral Replication ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.03c Describe the two most common methods for virion release from a host cell Accessibility : Keyboard Navigation Gradable : automatic 45) Which type of virus is most likely to be released by lysis of the host cell? A) Enveloped virus B) Nonenveloped virus Question Details Bloom's : 4. Analyze Section : 06.03 Topic : Viral Replication ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.03c Describe the two most common methods for virion release from a host cell Accessibility : Keyboard Navigation Gradable : automatic 46) For a temperate phage to produce more phage, which of the following must happen? Version 1 22 A) Lysogeny B) Induction C) Lysogenic conversion D) Prophage formation Question Details Bloom's : 4. Analyze Section : 06.04 Topic : Bacteriophage Cycles ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.04a Compare and contrast the major steps of the life cycles of virulent phages Accessibility : Keyboard Navigation Gradable : automatic 47) The production of cholera toxin by virulent strains of Vibrio cholera is dependent upon genes in a bacteriophage. This is an example of _________blank. A) lysogenic conversion B) induction C) bacterial transformation D) transduction Question Details Bloom's : 3. Apply Section : 06.04 Topic : Bacteriophage Cycles ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.04b Define lysogenic conversion Accessibility : Keyboard Navigation Gradable : automatic 48) Diphtheria toxin is produced only by strains of Corynebacterium diphtheriae that are infected with a particular bacteriophage. This is an example of _________blank. Version 1 23 A) conjugation B) induction C) lysis D) lysogenic conversion Question Details Bloom's : 3. Apply Section : 06.04 Topic : Bacteriophage Cycles ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.04b Define lysogenic conversion Accessibility : Keyboard Navigation Gradable : automatic 49) Which type of phage always lyses its host cell? A) Temperate B) Virulent C) Lysogenic D) Prophage Question Details Bloom's : 2. Understand Section : 06.04 Topic : Bacteriophage Cycles ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.04a Compare and contrast the major steps of the life cycles of virulent phages Accessibility : Keyboard Navigation Gradable : automatic 50) Which of the following encodes its own capsid proteins? Version 1 24 A) Satellite virus B) Satellite DNA C) Satellite RNA D) Prion Question Details Bloom's : 2. Understand Section : 06.06 Topic : Microbial World ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.06b Distinguish satellite viruses from satellite nucleic acids Accessibility : Keyboard Navigation Gradable : automatic 51) Which of the following is/are necessary for the replication of a satellite virus? A) Host cell only B) Helper virus only C) Prion only D) Host cell and helper virus Question Details Bloom's : 3. Apply Section : 06.06 Topic : Microbial World ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.06b Distinguish satellite viruses from satellite nucleic acids Accessibility : Keyboard Navigation Gradable : automatic 52) The most notable difference between PrPC (normal protein) and PrPSc (prion protein) is _________blank. Version 1 25 A) PrPC is a much longer polypeptide chain, compared to PrPSc B) PrPC causes a cell to undergo rapid apoptosis C) PrPc folds appropriately whereas PrPSc does not fold correctly D) PrPc is a functional glycolytic enzyme whereas PrPSc is nonfunctional Question Details Bloom's : 3. Apply Topic : Prions ASM Topic : Module 04 Information Flow and Genetics ASM Objective : 04.03 The regulation of gene expression is influenced by external and internal molecu Section : 06.07 Learning Outcome : 06.07a Describe prion structure and how prions are thought to replicate Accessibility : Keyboard Navigation Gradable : automatic 53) All of the following are methods of prion disease transmission except _________blank. A) ingestion of infected tissue B) inheritance (genetic) C) organ or tissue transplantation D) contamination through use of inadequately processed surgical instruments E) inhalation (airborne) Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07b List characteristics common to all animal diseases caused by prions Accessibility : Keyboard Navigation Gradable : automatic 54) What is the minimum number of phage that can initiate the development of a plaque in a bacterial lawn? Version 1 26 A) 1 B) 5 C) 10 D) 25 Question Details Bloom's : 2. Understand Section : 06.05 Topic : Bacteriophage Cycles ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.05c Outline the events that lead to formation of a plaque in a lawn of bacteria Accessibility : Keyboard Navigation Gradable : automatic 55) Virulent and temperate phages differ in that_________blank. A) virulent phages always result in the lysis of the host cell, whereas temperate phages may lyse the host cell, or they can enter a lysogenic cycle whereby they integrate their genome into the genome of the host cell B) temperate phages always result in the lysis of the host cell, whereas virulent phages may lyse the host cell, or they can enter a lysogenic cycle whereby they integrate their genome into the genome of the host cell C) temperate phages integrate their genome into that of the host cell, causing uncontrolled growth and ultimately lysis of the cell, whereas virulent phages remain in the lysogenic phase indefinitely D) virulent phages cause mutations in the host cell genome, whereas temperate phages have no genetic effect on the host cell Version 1 27 Question Details Bloom's : 5. Evaluate Section : 06.04 Topic : Bacteriophage Cycles ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.04a Compare and contrast the major steps of the life cycles of virulent phages Accessibility : Keyboard Navigation Gradable : automatic 56) Diseases caused by prions that are seen in domesticated animals and humans have which of the following manifestations in common? A) All diseases cause neurodegeneration B) All diseases cause gastrointestinal upset C) All diseases affect the cardiovascular system D) All diseases affect the musculoskeletal system E) All diseases cause skin lesions Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07b List characteristics common to all animal diseases caused by prions Accessibility : Keyboard Navigation Gradable : automatic 57) Viruses have a typical cellular structure like other living organisms. ⊚ ⊚ Version 1 true false 28 Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 58) Viruses in the extracellular state possess few, if any, active enzymes. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 59) Viruses infecting protists, including algae, have never been detected. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.01 Topic : Viruses ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.01b List organisms that are hosts to viruses Accessibility : Keyboard Navigation Gradable : automatic Version 1 29 60) One way in which small viruses package more information into a very small genome is to use overlapping genes so that the same base sequence is read in more than one reading frame. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 61) Almost all known plant viruses are RNA viruses. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.01 Topic : Viral Infections ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.01b List organisms that are hosts to viruses Accessibility : Keyboard Navigation Gradable : automatic 62) The most common capsid morphologies are icosahedral and helical. ⊚ ⊚ Version 1 true false 30 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.03b Discuss the role of receptors, capsid proteins, and envelope proteins in th Accessibility : Keyboard Navigation Gradable : automatic 63) The largest of the viruses are similar in size to some small bacteria and are large enough to be seen with a light microscope. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.02 Topic : Microbial World ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02a State the size range of virions Accessibility : Keyboard Navigation Gradable : automatic 64) The presence or absence of an envelope is not useful in classifying viruses because any given virus may at one time have an envelope and at another time not have an envelope. ⊚ ⊚ true false Question Details Bloom's : 3. Apply Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.01 The structure and function of microorganisms have been revealed by the use of m Learning Outcome : 06.02c Distinguish enveloped viruses from nonenveloped viruses Accessibility : Keyboard Navigation Gradable : automatic Version 1 31 65) Viruses such as MS2 and Qß pack additional information into their genomes through the use of overlapping genes. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.02 Topic : Viral Structure ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.02b Identify the parts of a virion and describe their function Accessibility : Keyboard Navigation Gradable : automatic 66) Enveloped viruses may enter their host cells by fusion of their envelope with the cytoplasmic membrane, thereby depositing their nucleocapsid within the cell. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Replication ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.03a Describe the five steps common to the life cycles of viruses Accessibility : Keyboard Navigation Gradable : automatic 67) Enveloped viruses may enter their host cells by engulfment within coated vesicles (endocytosis). ⊚ ⊚ Version 1 true false 32 Question Details Bloom's : 2. Understand Section : 06.03 Topic : Viral Replication ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.03a Describe the five steps common to the life cycles of viruses Accessibility : Keyboard Navigation Gradable : automatic 68) In a plaque assay, the number of infectious virions is usually identical to the number of virus particles present. ⊚ ⊚ true false Question Details Bloom's : 3. Apply Section : 06.05 Topic : Bacteriophage Cycles ASM Topic : Module 08 Microbiology Laboratory Skills ASM Objective : 08.04 Estimate the number of microorganisms in a sample (using, for example, direct c Accessibility : Keyboard Navigation Learning Outcome : 06.05b Define plaque-forming unit and explain its role in the quantification of vi Gradable : automatic 69) Like bacteria and eukaryotic microorganisms, most viruses can be cultured using artificial media. ⊚ ⊚ true false Question Details Bloom's : 3. Apply Section : 06.05 Topic : Viruses ASM Topic : Module 08 Microbiology Laboratory Skills ASM Objective : 08.02 Use pure culture and selective techniques to enrich for and isolate microorgani Learning Outcome : 06.05a List the approaches used to cultivate viruses, noting which types of viruse Accessibility : Keyboard Navigation Gradable : automatic Version 1 33 70) Bacterial viruses are so named because they have prokaryotic cell structures similar to their bacterial hosts. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Section : 06.01 Topic : Bacteriophage Cycles ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Learning Outcome : 06.01a Define the terms virology, bacteriophage, and phage Accessibility : Keyboard Navigation Gradable : automatic 71) Prions consist of proteins and have no apparent nucleic acid genome. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 06 Impact of Microorganisms ASM Objective : 06.02 Microorganisms provide essential models that give us fundamental knowledge abou Section : 06.07 Learning Outcome : 06.07a Describe prion structure and how prions are thought to replicate Accessibility : Keyboard Navigation Gradable : automatic 72) Available evidence is consistent with the proposal that prion diseases are caused by infectious proteins. ⊚ ⊚ Version 1 true false 34 Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07a Describe prion structure and how prions are thought to replicate Accessibility : Keyboard Navigation Gradable : automatic 73) The mechanism of pathogenesis by prions may involve a conformational change in the prion protein (PrP) to an abnormal form. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07a Describe prion structure and how prions are thought to replicate Accessibility : Keyboard Navigation Gradable : automatic 74) There are no known human diseases that have been linked to prions. ⊚ ⊚ true false Question Details Bloom's : 2. Understand Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07c Name at least two human diseases caused by prions Accessibility : Keyboard Navigation Gradable : automatic Version 1 35 75) A temperate phage always lyses its host cell. ⊚ true ⊚ false Question Details Bloom's : 1. Remember Section : 06.04 Topic : Bacteriophage Cycles ASM Topic : Module 02 Cell Structure and Function ASM Objective : 02.05 The replication cycles of viruses (lytic and lysogenic) differ among viruses an Learning Outcome : 06.04a Compare and contrast the major steps of the life cycles of virulent phages Accessibility : Keyboard Navigation Gradable : automatic 76) A PrPc protein can convert a PrPSc to a PrPc. ⊚ true ⊚ false Question Details Bloom's : 4. Analyze Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.03 Microorganisms and their environment interact with and modify each other. Section : 06.07 Learning Outcome : 06.07a Describe prion structure and how prions are thought to replicate Accessibility : Keyboard Navigation Gradable : automatic 77) Creutzfeldt-Jacob disease is known to have been transmitted by surgical instruments and transplanted nerve tissue. ⊚ true ⊚ false Version 1 36 Question Details Bloom's : 1. Remember Topic : Prions ASM Topic : Module 05 Microbial Systems ASM Objective : 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman h Section : 06.07 Learning Outcome : 06.07c Name at least two human diseases caused by prions Accessibility : Keyboard Navigation Gradable : automatic Version 1 37 Answer Key Test name: Prescotts Microbiology 12e Willey TB 06 1) Peplomers 2) capsomers 3) icosahedral 4) transformation 5) cytopathic effects 6) necrotic 7) bacteriophages 8) B 9) C 10) C 11) C 12) D 13) D 14) C 15) C 16) B 17) B 18) B 19) B 20) C 21) C 22) D 23) B 24) D 25) B 26) A Version 1 38 27) B 28) B 29) D 30) A 31) C 32) B 33) D 34) D 35) D 36) B 37) C 38) C 39) D 40) A 41) D 42) A 43) D 44) C 45) B 46) B 47) A 48) D 49) B 50) A 51) D 52) C 53) E 54) A 55) A 56) A Version 1 39 57) FALSE 58) TRUE 59) FALSE 60) TRUE 61) TRUE 62) TRUE 63) TRUE 64) FALSE 65) TRUE 66) TRUE 67) TRUE 68) FALSE 69) FALSE 70) FALSE 71) TRUE 72) TRUE 73) TRUE 74) FALSE 75) FALSE 76) FALSE 77) TRUE Version 1 40