Official reprint from UpToDate® www.uptodate.com © 2023 UpToDate, Inc. and/or its affiliates. All Rights Reserved. © 2023 UpToDate, Inc. and/or its affiliates. All Rights Reserved. Spinal cord syndromes Syndrome Segmental (transection) syndrome Clinical manifestations Loss of all sensory modalities, weakness below affected level; Causes Trauma, hemorrhage, epidural abscess, transverse myelitis, epidural metastasis : bladder dysfunction Dorsal cord Loss of proprioception, Tabes dorsalis, Friedreich ataxia, subacute syndrome vibratory sensation; variable weakness and bladder dysfunction combined degeneration, AIDS myelopathy, epidural metastases, cervical spondylotic myelopathy, multiple sclerosis Ventral cord syndrome Loss of pain and temperature sensation, Spinal cord infarction, disc herniation, radiation myelopathy, HTLV-1 (anterior spinal artery syndrome) weakness, bladder dysfunction Brown Sequard syndrome Ipsilateral weakness and loss of proprioception; contralateral loss of pain and temperature sensation Knife or bullet injury, multiple sclerosis Central cord Segmental loss of pain Syringomyelia, intramedullary tumor, syndrome and temperature, weakness often greater in the arms than legs acute injury in cervical spondylotic myelopathy Pure motor syndrome Weakness without sensory disturbance Poliomyelitis, amyotrophic lateral sclerosis, HTLV-1, hereditary spastic paraplegia, lathyrism Conus Bladder and rectal medullaris syndrome dysfunction, saddle anesthesia Cauda equina syndrome Asymmetric multiradicular pain, leg weakness, and sensory loss; bladder dysfunction : Graphic 62066 Version 1.0 Disc herniation, trauma, tumors Disc herniation, arachnoiditis, tumor, lumbar spine stenosis