Name: Class: Date: Protein Folding and Protein Structure Examine the diagrams and fill in the letter in each blank below. Some blanks have more than one letter answer. Then answer the two questions below. A B M E P K L I T F T S F S Q D C E ______ 1. primary structure ______ 2. secondary structure ______ 3. tertiary structure ______ 4. quaternary structure ______ 5. held together primarily with hydrogen bonds ______ 6. held together primarily through R group interactions ______ 7. consists only of the sequence of amino acids ______ 8. contains more than one polypeptide subunit ______ 9. contains more than one helix, sheet, or other simple structure ______ 10. beta strand (sheet) ______ 11. alpha helix ______ 12. globular shape Folded Normal Temperature Range Unfolded Folded 13. In the picture above, one color is used for the amino acids with hydrophilic R groups and one color is used to show amino acids with hydrophobic R groups. Which color is which? How do you know? 14. When a protein is exposed to temperatures outside its normal range, it “denatures”. What does “denature” mean? Explain your answer below. _________________________________________________________ _________________________________________________________ _________________________________________________________ _________________________________________________________ _________________________________________________________ _________________________________________________________ (C) Bethany Lau 2016 Name: Answer Key Class: Date: Protein Folding and Protein Structure Examine the diagrams and fill in the letter in each blank below. Some blanks have more than one letter answer. Then answer the two questions below. A B M E P K L I T F T S F S Q D C E A ______ 1. primary structure B,C 2. secondary structure ______ D ______ 3. tertiary structure E ______ 4. quaternary structure B,C 5. held together primarily with ______ hydrogen bonds D 6. held together primarily through ______ R group interactions A ______ 7. consists only of the sequence of amino acids E ______ 8. contains more than one polypeptide subunit D,E 9. contains more than one helix, ______ sheet, or other simple structure B ______ 10. beta strand (sheet) C ______ 11. alpha helix D ______ 12. globular shape Folded Normal Temperature Range Unfolded Folded 13. In the picture above, one color is used for the amino acids with hydrophilic R groups and one color is used to show amino acids with hydrophobic R groups. Which color is which? How do you know? 14. When a protein is exposed to temperatures outside its normal range, it “denatures”. What does “denature” mean? Explain your answer below. In the diagram, the black colored amino acids are the _________________________________________________________ Denaturation means the polypeptide unfolds or changes _________________________________________________________ from its normal shape. In the picture, the normally polypeptide, away from the water molecules surrounding _________________________________________________________ the polypeptide. folded protein is shown at the top. But when the _________________________________________________________ temperature drops too low or the temperature goes too hydrophobic ones. They fold into the inside of the folded _________________________________________________________ (C) Bethany Lau 2016 high, the protein unfolds or folds in a different way from _________________________________________________________ its normal shape needed for function. TErms of Use Thank you so much for purchasing one of my teaching resources! 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Other graphics in my resources are licensed and used with permission from the following artists/sources: This Page is part of my Biology Homework for the Whole Year Bundle Units (Red Completed, Others show upload dates) 1. Introduction to Life and Scientific Method 2. Biochemistry 3. Cells and Organelles This bundle is growing!!! 4. Cell Transport Purchase now to get 5. Enzymes and Cell Energetics all future units free! 6. Cell Division (by Sep 30) 7. DNA, RNA, and Protein synthesis (by Oct 30) 8. Genetics (by Nov 30) 9. Evolution (by Dec 30) 10. Ecology (by Jan 30) Why did I create this bundle: I struggled as a teacher to find time to make meaningful homework pages with: * diagrams and pictures, where students draw, circle, color, and truly interact with the material in a visual way * great reading passages that connected directly with a unit’s material * questions that go DEEPER! To prepare for when I go back to teaching (I’m at home with my kids for a few years), I created this bundle. This bundle is a labor of love, creativity, and a lot of hours in Adobe Illustrator. These pages are not a combination of my previously published activities. These pages are all truly unique. For every major concept I teach in First Year Biology, there will be a one-sided homework page!
