Sex Linked Traits • • • • Traits controlled by genes located on sex chromosomes Genes on the X-chromosome are called _________________ Since males only have one X-chromosome, they are often affected by recessive X-linked traits more than females Females have a second X-chromosome that may “________” the recessive trait Ex. Red-Green Colour Deficiency • Recessive X-linked trait • 8-10% of males have this deficiency • Ex. Mother is a carrier for the colour deficiency • Dad does not have the gene for colour deficiency • Only possibility is for a male (XY) child to have this deficiency! • As a result, very rare in females Multiple Alleles • The traits we have studied so far have all been controlled by one gene with two alleles • Many traits are the result of the interaction between _________________________ for one gene – multiple alleles • This is why for some traits, there are more than just two options Ex. Blood Types • In humans, a single gene determines a person's ABO blood type • This gene determines which type of ___________ protein, if any, is attached to the cell membrane of red blood cells • An antigen is a molecule that stimulates the body's immune system • There are three common alleles: ______, ______ and ______ • The combinations of these three alleles produce _____ different phenotypes, commonly called blood types • Blood Types: • A – IAIA or IAi - dominant • B – IBIB or IBi - dominant • AB – IAIB • O – ii – recessive • The IA allele has an A antigen, IB a B antigen, and i has __________________ • No antigen = blood can be donated to any other blood type ______________ donor if type O Ex. Rabbit Coat Colour • Four alleles: Agouti ______, Chinchilla _____, Himalayan _______ and Albino _________ • Order of dominance: > > > Problem: • A man has type O blood and a woman has type B blood – what possible blood types could their children have? If the couple has six children, all with type B blood, what could you infer about the woman's genotype? • Parent genotypes: Dad must be _______, mom could be ______ or ______ • Perform two crosses to determine possibilities Results: Polygenic Inheritance • There are traits that exhibit what is called _____________ __________________ – a range of variations within one trait • For example, skin colour or height in humans • Continuous traits occur over a ______________ - people cannot be categorized as one thing or another • Traits that exhibit this variation are controlled by more than one gene, and are called _____________ ____________ • A group of genes that all contribute to the same trait is called a ______________ • Each dominant allele contributes to the trait, while recessive alleles do not contribute to the trait • Ex. The more dominant alleles one has for skin colour, the darker the skin will be