AP Biology 038 – Signal Transduction Pathways Video Review Sheet www.bozemanscience.com/038-signal-transduction-pathways 1. Signal Transduction Pathways start with a message in the form of a chemical message that is tranduced into actions within the cell. 2. Two types: 1. Protein modification 2. Phosphorylation cascade: a phosphate that has energy is passed from one chemical to another until it eventually has an action. 3. Example with G-Protein in the Liver: 1. Messenger: Epinephrine 2. The messenger docks with the receptor – specifically the G-Protein Receptor 3. Ligand: a chemical that can’t make its way across a cell membrane 4. When epinephrine binds it changes the shape of the G-Protein. What is released? Alpha Subunits 5. Adenylyl cyclase is initially an inactivated enzyme 6. When the alpha subunit is bound to adenylyl cyclase it converts ATP to cAMP 7. cAMP is a secondary messenger 8. Protein kinase is inactivated when the regulatory portions are bound. 9. cAMP binds to the regulatory portions and releases the catalytic portions. 10. The catalytic portions of protein kinase become phosphorylated and are activated they then can act on enzymes throughout the cell. 4. How did you do when you played Dora the Explorer? Great!! 5. How can this whole process be “amplified”? Phosphorylation Review Sheet for AP Biology 038 – Signal Transduction Pathways Contributed by Winnie Litten — YouTube - /mslittenbiology Twitter-@mslittenbiology This study source was downloaded by 100000843794725 from CourseHero.com on 12-09-2022 11:26:00 GMT -06:00 https://www.coursehero.com/file/63290600/Bozeman-No-038docx/ This study source was downloaded by 100000843794725 from CourseHero.com on 12-09-2022 11:26:00 GMT -06:00 https://www.coursehero.com/file/63290600/Bozeman-No-038docx/ Powered by TCPDF (www.tcpdf.org)
