Fibroadenoma Most common tumor of breast Age 15-25 yr Nature? Benign (Part of ANDI..hyperplasia of single lobule) Size Small….usually <2cm If >5cm…giant fibroadenoma Slow progression Less Smooth, firm, painless, nontender, well localized, Duration Recurrence Clinical features freely movable swelling in one of the quadrants (mouse of the breast) Axillary LAP Mammo US Cytology Treatment No Macroscopically (soft, hard type) Microscopically (intracanalicular..large soft, pericanalicular..small hard) Phylloid tumor (Cystosarcoma) Not simply giant fibroadenoma Phyllodes…leaf like (on microscopy) Older (40-50) pre-menopausal women (30-50) Wide spectrum of activity Almost benign (85%) Locally aggressive & sometimes metastatic (15%)…to lung/bond Large, bosselated Rapid growth Common Smooth, soft, fluctuant, nontender Skin changes skin necrosis, streching, and redness and dilated veins over it usually unilateral, Tumor is warmer, not fixed to skin or chest wall, nipple retraction is absent. usually no Grossly, it is large capsulated area with cystic spaces and cut surface shows soft , brownish cystic areas. Microscopically (cystic spaces with leaf like projections) Same findings Send for CXR, CT chest in phyllodes Excision Excision/ subcutaneous mastectomy If malignant (sarcoma)…total mastectomy Cyclical mastalgia (2 thirds) 30-50 yr It is linked to the menstrual cycle, increasing in severity in the days preceding menstruation and then decreasing after the onset of menses Bilateral Aching pain or heaviness affecting the upper outer quadrants of the breast. Non cyclical mastalgia (1 third) More common in older & pPost menopausal women Localized breast pathology large cysts in fibrocystic disease periductal mastitis engorgement during lactation breast abscess Unilateral Sharp burning or localized pain in one quadrant Extra-Mammary (non breast) pain arises from the chest wall or other sources and its interpreted as a cause within the breast like Mondors disease and Tietz syndrome (Costochondritis) Pain Vomiting Periodicity Complications Gastric ulcer After meal Aggravated by eating Relieved by fasting More (due to pyloric spasm) Green, sore No known/less periodicity Bleeding is less common but dangerous (from main arteries..left gastric/ splenic artery) Hematemesis is more (pyloric spasm) Duodenal ulcer Hunger pain Aggravated by fasting Relieved by eating Yellow, bitter More (Symptoms more prominent in certain time of year) Most commonly from posterior DU (gastroduodenal artery) Melena is more