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Lab values

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Lab Values
Basic Metabolic Panel
- Sodium: 135-145
- Potassium: 3.5-5.0
- Chloride: 98-106
- BUN: 6-20
- Glucose: 70-99
- Creatinine: Male (0.6-1.2), Female (0.5-1.1)
Complete Blood Count
- RBC’s: Male (4.7-6.1), Female (4.2-5.4)
- Hemoglobin: 10-18
- Hematocrit: 30-48
- WBC’s: 4,000-11,000
Lipid Studies
- Total Cholesterol: Less than 200
- HDL Cholesterol: Male (greater than 45), Female (greater than 55)
- LDL Cholesterol: Less than 130
- Triglycerides: Male (40-160), Female (35-135)
Liver Function Studies
- Albumin: 3.3-5
- Bilirubin: 0.3-1.0
- ALT: 4-36
- AST: 0-35
- Alkaline Phosphatase: 30-120
Cardiac Marker Studies
- Creatinine Kinase: Elevated indicates damage in skeletal, cardiac or
brain tissue: Male (55-170), Female (30-135)
- CK-MB: Greater than 3 is abnormal.
- Myoglobin (released with damage): Greater than 90 is abnormal
- Troponin I (found in cardiac muscle): Greater than 0.04 is abnormal
- Troponin T (cardiac muscle): Greater than 0.1 is abnormal
Urine Studies
- Specific Gravity: 1.005-1.030
- Glucose: Should be negative, positive indicates DM or infection.
- Ketones: Should be negative
- Protein: 0-8
- Bilirubin: Should be negative, positive with hepatic issues.
ABG’s
- pH: (acidotic) 7.35-7.45 (basic, alkalosis)
- PaCO2: (basic) 35-45 (acidotic) Respiratory Marker
- HCO3 (bicarbonate): (acidotic) 22-26 (basic) Metabolic Marker
- PaO2: 80-100: Lower marks hypoxemia
Electrolytes and Acid Base
Respiratory Acidosis
- Caused by: Hypoventilation (buildup of CO2)
- COPD, overdose, low ventilation
- Increased PaCO2, decreased pH
- Manifestations:
- Neuro: Lethargy, confusion, dizziness, headache.
- CV: hypotension, warm/flushed skin.
- Seizures and hypoventilation with hypoxia.
Respiratory Alkalosis
- Caused by: Hyperventilation (anxiety, fear, exercise) or mechanical
- Decreased PaCO2, Increased pH
- Manifestations:
- Neuro: Dizziness, confusion, headache
- CV: Tachycardia, arrhythmias
- GI: N/V/D, epigastric pain
- Neuromuscular: tetany, numbness, tingling, hyperreflexia
Metabolic Acidosis
- Caused by: DKA, diarrhea, starvation, renal failure, shock.
- Decreased pH, decreased HCO3.
- Manifestations:
- Neuro: lethargy, confusion, dizziness, headache, muscle
weakness.
- CV: hypotension, cold/clammy skin.
- GI: N/V/D, abdominal pain.
Metabolic Alkalosis
- Caused by: Prolonged gastric suctioning, vomiting, diuretics.
- Increased HCO3, Increased pH
- Manifestations:
- Neuro: Irritability, lethargy, confusion, headache.
- CV: Tachycardia, arrhythmias.
- GI: Nausea, vomiting, anorexia
- Neuromuscular: tetany, tremors, tingling, cramping, seizures.
Fluids
-
-
-
Isotonics
- 5% Dextrose in water
- 0.9 Saline
- 5% Dextrose in 0.25 Saline
- Ringer’s solution
- Lactated Ringer’s (not to use with renal or hepatic issues)
Hypertonics
- 10% Dextrose
- 3.0% Saline
- 5% Dextrose in 0.45 Saline
- 5% Dextrose in 0.9 Saline
Hypotonics:
- 0.45% Saline
- 5% Dextrose in water
Random
-
-
Intraocular Pressure (IOP): 10-21 mmHg
Intracranial Pressure (ICP): 5-15 mmHg
Urine Output: Greater than 30 ml/h
Cerebral Perfusion Pressure: 60-100 mmHg
- Less than 50 equals ischemia and neuronal death
- Less than 30 equals ischemia and is incompatible with life.
- MAP-ICP=CPP
Mean Arterial Pressure: Greater than 65
- Systolic + Diastolic X2 / 3
Drainage Types
-
Serous drainage: clear to yellow, expected from wounds.
Serosanguineous drainage: pink
Sanguineous: red
Cranial Nerves
-
I Olfactory: Sensory from olfactory (smell)
II Optic: Sensory from retina (vision)
III Oculomotor: Motor for eye movement
IV Trochlear: Motor for eye movement
V Trigeminal:
VI Abducens: Motor for eye movement (3,4,6 tested together)
VII Facial: Motor for facial expression and cheek muscle.
VIII Vestibulocochlear: Sensory in the ears.
IX Glossopharyngeal: Sensory and motor for tongue.
X Vagus: Sensory from viscera and thorax, motor for larynx
XI Accessory: Motor for sternocleidomastoid and trapezius.
XII Hypoglossal: Motor to muscles of tongue.
Cardiovascular Values
-
-
-
Systole: Contraction of heart muscles (pumping)
Diastole: Relaxation of the heart muscles (filling)
Pulse Pressures: SBP-DBP
- Normal is around 30-40 (if your BP is good, you PP is good).
Systolic Blood Pressure: Peak pressure in arteries with contraction.
Diastolic Blood Pressure: Residual pressure in arteriole system with
Ventricular relaxation (filling)
Cardiac Output: Amount of blood pumped by the ventricles in 1 min.
- Stroke Volume X Heart rate = CO
- 4-8 for the average resting adult.
Cardiac Index: Cardiac output divided by body surface area.
- 2.8-4.2 considered normal.
Stroke Volume: Volume squeezed out with each contraction.
Preload: Volume of blood stretching the ventricles at the end of
diastole.
- May decrease with tachycardia or hypovolemia.
- May increase with hypertension, aortic valve disease,
hypervolemia.
Afterload: Peripheral resistance that the left ventricle must pump
against.
Electrolytes
-
Hypernatremia: Greater than 145
- Causes: Excessive intake, inadequate water intake, excessive
water loss, DI, cushings, uncontrolled diabetes.
- Manifestations
- Restlessness, lethargy, thirst, dry swollen tongue,
tachycardia, decreased CVP, muscle cramps
- Treatment: fluid replacement, diuretics
-
Hyponatremia: Less than 135
- Causes:
- Excessive sodium loss: diarrhea, vomiting, suctioning.
- Renal losses: diuretics, adrenal insufficiency.
- Skin: burns, wound damage.
- Inadequate intake, excessive water intake.
- Diseases: SIADH, HF, Cirrhosis.
- Manifestations:
- Irritability, confusion, muscle spasms, N/V/D, weight gain,
hypertension, increased CVP.
- Treatment: Replace sodium.
-
Hyperkalemia: Greater than 5.0
- Causes: excessive intake, renal disease, medications sparing
potassium.
- Manifestations: fatigue, irritability, muscle weakness, loss of
muscle tone, decreased reflexes, diarrhea, confusion, tetany.
- EKG changes: arrhythmias high risk (V Fib)
- Tall T waves, wide QRS, prolonged PR, ST
depression.
- Interventions:
- Stop oral intake,
- Increase excretion (polystyrene sulfonate)
- Force K+ to ICF: Insulin w/ Dextrose
-
Hypokalemia:
- Causes: Potassium loss (V/D, diuretics, diaphoresis), lack of
intake.
- Manifestations: fatigue, muscle weakness, decreased reflexes,
shallow respirations, irregular pulse, nausea.
- ECG changes: risk for ventricular arrhythmias, first and
second degree heart block.
- Flattened T wave, ST depression, prolonged QRS.
- Interventions: Supplements or increasing in diet.
-
Hypercalcemia:
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