DIFFUSE GOITRE WITH HYPOTHYROIDISM M. Vidhya Roll. No 92 S3 unit department of surgery 32 years female Mrs.Shanthi from Valavanur house wife by occupation came to OPD with c/o swelling in the front of neck for past 6 months History Of Presenting Illness Patient was apparently normal before 6 months then she noticed swallowing in the front of the neck which was noticed by herself. - Insidious in onset - Initially small in size gradually progresive to attained present size - Not associated with pain - No H/O Any other swelling in neck - No H/O Trauma - No H/O Fever - No H/O Difficulty in breathing - No H/O Difficulty in swallowing - No H/O Voice change - No H/O Syncope - No H/O Excess sweating - No H/O Loss of weight - No H/O Heat intolerance - No H/O Diarrhoea - No H/O Sleepless night - No H/O Muscle weakness - No H/O Tumors - No H/O Difficulty in closing eyes - No H/O Double vision - H/O fatigue - H/O weight gain (in spite of poor appetite) - H/O cold intolerance - H/O constipation - H/O loss of hair - No H/O Hoarseness of voice - H/O Oligomenorrhea (once in 45 days) - No H/O Palpitation - No H/O Dyspnea on exertion - No H/O Ankle edema - No H/O Chest pain - No H/O Loss of appetite - No H/O Chronic cough with hemoptysis - No H/O Headache - No H/O Vomiting - No H/O Bone pain - No H/O Any other swelling in neck - No H/O Jaundice Past History - No H/O Similar illness in the past - No H/O Diabetes Mellitus,Tuberculosis, Bronchial asthma, Epilepsy, Hypertension - No H/O Previous neck surgeries - No H/O Irradiation - No H/O Drug intake Personal History - Consumes mixed diet, not smoker, not alcoholic - Normal sleep pattern - No H/O Substance abuse, takes iodized salt - No H/O Excessive intake of goitrogens Family History -No Significant family history Menstrual History - Age at menarche - 14 years - Oligomenorrhea parent - Irregular cycle once in 45 days - Normal flow (for 5 days) - No clots not associated with pain - No H/O use of OCP pills Marrital History -Non-consanguineous marriage -Have 2 children Summary 32 years old female Mrs.Shanthi came to OPD with chief complaints of swelling in anterior aspect of neck for past 6 months insidious in onset, initially small in size gradually progresive to attained present size not associated with pain with history of hypothyroidism, no history suggestive of hyperthyroidism, no history suggestion of metastasis, with no other relevant Significant history, probably a case of benign thyroid swelling. With this given complaint I would like to examine this swelling. General Examination After getting consent from the patient was examined in a sitting position. Patient was comfortable, oriented, moderately built and nourished - Pallor present - No icterus - No Cyanosis - No Clubbing - No evidence of toxic eyesigns General Survey - Hair : Hair loss present - Skin : Dry - Face : Mask Like face - Limbs : No tumor - Eyes : No toxic eyesigns - Oral cavity : Mactoglossia present Vitals - Pulse Rate : 56/min [normal rhythm, volumes character] - No radio delay, - No radiofemoral delay - No vessel wall thickening - BP : 110/70 mmHG - Temperature : Afebrile - Respiratory rate : 18/min Local Examination Inspection A diffuse swelling of size 10*8 cm present on the anterior aspect of the neck which is in butterfly shape. - Extent : above : Thyroid cartilage below : Sternal notch Lateral : Sternocleidomastoid - Smooth surface - Well defined margin - Swelling moves with deglutition - Lower border of swelling seen - Skin one swelling normal - No sinus scar,dilated veins - No visible pulsation - No other swelling in neck - Trachea position not seen due to differs swelling Palpation - Not warmth, not tender - Inspectory findings about site size shape, size extent surface of swelling is confirmed - Firm is consistency - Mobility : Moves with deglutition - Trachea in midline - No other swelling present - Carotid pulsations felt on both sides - No palpable thrill - Kocher’s test : negative - Pemberton sign : not applicable Auscultation - No bruit heard over gitre Systemic Examination - RS : normal vesicular breath sounds - CNS : S1S2 heard No murmur - Abdomen : Soft, non-tender, no free fluid, no organomegaly - CNS : No focal neurological deficit Summary 32 years old female Mrs.Shanthi came to OPD with chief complaints of swelling in anterior aspect of neck for past 6 months, with history of hypothyroidism on examination, diffuse painless swelling of size 10*8 cm seen on the anterior aspect of neck butterfly shaped margins well defined, firm in consistency, with no palpable lymph nodes. Provisional diagnosis If is a case of diffuse goitre with hypothyroidism Investigations 1. Thyroid function test 2. USG neck 3. FNAC 4. CBC X-ray of neck, chest X-ray 5. ANH Thyroid peroxidase 6. Anti-TAG