ndBiol 2402 Exam 1 Review questions 1. What are 2 main characteristics of a hormone? a. long-distance chemical messengers b. travels in blood or lymph 2. From what material are steroid hormones derived? a. cholesterol 3. A hormone binds a ________ a. receptor 4. A protein or peptide hormone usually requires a ______ to send its signal inside a cell. a. cell membrane receptor 5. Another word for a first messenger is a(n) ________ a. hormone 6. What are 2 common second messengers? a. cAMP & PIP2 (calcium) 7. What would be the problem with excess PTH in the bloodstream? a. higher levels of blood calcium 8. The end result of most hormone action in the cell is what? a. increase growth or enzyme activity 9. Another name for the pituitary gland is the ________ a. hypophysis 10. What are the 2 classes of hypothalamic regulatory hormones? a. inhibitory and releasing 11. Most tropic hormones originate from what part of the pituitary? a. anterior pituitary adnohypothesis 12. Where are ADH and oxytocin found? a. posterior pituitary gland 13. Of the thyroid hormones regulating metabolism, which is the most active? a. T3 14. Thyroid hormones need what element in order to function? a. iodine 15. Parathyroid hormone helps increase blood levels of what? a. Ca2 (calcium) 16. In what region of the suprarenal gland are the catecholamines produced? a. adrenal medulla 17. What are 2 main effects of glucocorticoids? a. keeps blood glucose levels constant & maintains BP 18. Another name for cortisol is __ a. hydrocortisone 20. Melatonin is secreted from which gland? pineal gland 21. An example of an organ with both exocrine and endocrine functions would be _______ pancreas 22. Where is insulin produced? Beta cells in the pancreatic islets of the pancreas 23. If blood sugar drops too low, what hormone will be released to re-establish balance? Where is this produced? glucagon; Alpha cells in the pancreatic islets of the pancreas 24. What is the main difference between type 1 and type 2 diabetes? Type 1 - hyposecretion (not producing insulin, beta cells inadequate) autoimmune ; Type 2 hypoactivity (something wrong w/ cell membrane or hormone) insulin sensitivity 25. Situations requiring split second responses or crisis management, is the job of what system? SNS (sympathetic nervous system) 26. Plasma is mostly ______ a. water 27.What are 3 primary classes of plasma proteins? albumin, globulins, fibrinogens 28.What is the average blood pH? 7.4 29.Iron is a component of what major red blood cell protein? heme of hemoglobin 30.Red blood cells (RBCs)lack what major organelles? ALL - RBC's are anucleate (no organelles) 31.What is the average life of RBCs? 100-120 days 32.What are some advantages to the shape of RBCs? larger surface area contributing to gas transport pass through small capilaries 33.Where is the primary site of erythropoiesis in the adult? red bone marrow (axial skeleton, girdles & proximal epiphyses of humerus & femur) sternum 34.Which leukocyte is the most common granulocyte? neutrophils 35. EPO is produced by what organ and has what effect on the blood? a. kidneys; raises level of RBC production 36. A person with type O blood contains what antibodies? a. anti-A & anti-B 37. Platelets are derived from what cell? Are platelets actual cells? a. megakaryocytes; no, just fragments of cells 38. What blood protein is a major component of blood clots? a. fibrin 39. T and B cells are what major type of leukocyte? a. lymphocyte 40. Which leukocytes are producers of antibody? a. B cells of lymphocyte 41. What is the site of most gas and nutrient exchange in the tissues? a. capillaries 42. What is the condition in which a traveling clot blocks a blood vessel? a. embolism 43. Vitamin B12 deficiency is also known as what? a. pernicious anemia 44. Leukemia is characterized by what? a. over production of WBC's (white blood cells) 45. Thrombin converts what protein to fibrin? a. fibrinogen 46. In what direction do arteries carry blood? What is the direction in veins? a. arteries - from body to heart (or from body-heart-lungs) ; veins - gtom heart to body (or from lungs-heart-body) 47. Which are the most muscular chambers of the heart? Why? a. ventricles; actual pumps of the heart 48. Where does blood go after leaving the right ventricle? a. to the lungs pulmonary circulation 49. Where does blood go after leaving the left ventricle? a. to the body systemic circulatory 50. Name the three layers of the heart wall a. epicardium, myocardium, endocardium 51. What type of blood travels through the pulmonary artery? The aorta? a. deoxygned blood pulmonary 52. What is the function of valves? a. keeps blood moving in one direction 53. Where is blood pressure the highest? Where is it the lowest? a. highest left ventricle and aorta lowest right atrium 54. Through what vessels does the heart get supplied with blood? a. coronary artiers 55. In an EKG, the height of the waves represents what electrical property? a. voltage 56. What part of the EKG corresponds to ventricular depolarization? a. QRS Complex 57. Rh-positive blood indicates the presence of what antigen? a. D-antigen 58. What do the formed elements consist of? a. erythrocytes (RBC's), leukocytes (WBC's), and platelets 59. What is the difference between serum and plasma? a. serum is missing RBC's, WBC's, and fibrinogen (no clotting factors)