FLG 211 Unit 2.1 Skeletal Muscle Lecture 3 Prof Peet du Toit Sources for ATP for Muscle Contraction Acid, Bases, and pH • Acid • • Molecule that can liberate H+ ions Base • Molecule that is capable of combining with H+ ions • pH • Measure of H+ ion concentration pH = -log10[H+] pH of Blood • Normal − • pH = 7.4 Acidosis − pH < 7.4 • Alkalosis − pH > 7.4 • Abnormal pH performance can disrupt normal body function and affect Sources of Hydrogen Ions Due to Metabolic Processes Importance of Acid-Base Regulation During Exercise • Failure to maintain acid-base balance performance − Inhibit ATP production − Interfere with muscle contraction • Acid-base balance maintained by buffers − Release H+ ions when pH is high − Accept H+ ions when pH is low may impair Lines of Defence Against pH Changes During Intense Exercise Thank You FLG 211 Unit 2.1 – Skeletal Muscle
