Mechanisms that Produced Change in Populations Most Essential Learning Competency (MELC) Explain the mechanisms that produce change in populations from generation to generation (e.g., artificial selection, natural selection, genetic drift, mutation, recombination) (STEM_BIO11/12/-IIIc-g-9) Key Concepts Evolution, the gradual process of change, is naturally occurring among populations at negligible rate. In nature, populations such as grasses, birds, dolphins and other organisms, and even the Covid-19 virus, are usually evolving. What are the mechanisms that produce change in populations from generation to generation? 1. Natural Selection. Charles Darwin introduced natural selection as evolution process which hypothesize that all forms of life came from a common ancestry which developed into various forms as they adapted to their environment. Based on the theory, the population is controlled by several factors in the environment. Organisms that possessed favorable traits and who can better adapt to their environment will survive, leaving behind many offspring; while those that failed to adapt, will leave fewer offspring and will die and may totally disappear. Natural selection results in the accumulation of new variations and the loss of unfavorable ones, giving rise to new species. This theory summarizes the famous evolutionary context “survival of the fittest” (see Figure 1). Source: pinterest.ph/pin/478929741621/ Figure 1 Natural Selection of Nature 2. Artificial selection. Farmers and genetic engineers intentionally prefer "selective breeding”, where they select desirable traits in agricultural products or animals, rather than leaving the species to evolve and change gradually without human interference. Over the course of decades, selection was used by farmers and breeders to cause major changes in the characteristics of their plants or animals. Selectively using only, the plants and animals with desirable characteristics to reproduce, causing the evolution of farm stock. As shown in Figure 2, farmers have cultivated numerous popular crops from the wild mustard, by artificially selecting their preferred attributes. Source: evolution.berkeley.edu/evolibrary/article/evo_30 Figure 2 These common vegetables were cultivated from forms of wild mustard. This is evolution through artificial selection. 3. Genetic Drift. It describes random fluctuations in allele frequencies in a population. Eventually, genetic drift can cause a subpopulation to become genetically distinct from its original population. Over a long period of time, genetic drift and the accumulation of other genetic changes can result in speciation, which is the evolution of a new species. The cheetah shown in Figure 3 is a species whose evolution has been seriously affected by genetic drift which caused their population to decline over the last 5,000 years. As a result, most of the cheetah’s descendants are almost genetically uniform with each other. One consequence of this genetic uniformity is reduced disease resistance- cheetah cubs are more likely to die from disease than the cubs of lions or leopards. The main reason of their hasten extinction than the other species. One example of genetic drift is Source: cheetahlearning.com/wp/further faster/ a Bottleneck effect which may Figure 3 Cheetahs are endangered. Cheetahs have gone happen when the size of a population through at least two drastic declines in population size. is severely reduced. Also, natural disasters like earthquakes, floods, fires can lessen a population, leaving behind a small, random assortment of survivors. 4. Mutation. It is a permanent change in the DNA sequence of a gene. It may sometimes useful but mostly mutation is harmful because it changes the way a cell behaves. That is, when the genes which contain instructions necessary for a cell to work is changed or mutated, then the cell may not know what it is supposed to do. Mutations are divided into two general types based on the ranges in size from a single DNA base to a large segment of a chromosome. These two general types are DNA mutations and chromosomal mutations. DNA mutations are mutations that happen when there are changes in the nucleotide sequence of the DNA while chromosomal mutations are mutations that occur when there are changes or abnormalities in the Source: shutterstock.com/search/translocation Figure 4: Types of Chromosomal Mutations structure and number of chromosomes. Chromosomal mutations are also called chromosomal abnormalities or chromosomal aberrations (See Figure 4). 5. Recombination. It is a process by which pieces of DNA are broken and recombined to produce new combinations of alleles. This recombination process creates genetic diversity at the level of genes that reflects differences in the DNA sequences of different organisms. Recombination typically occurs during meiosis in eukaryotic cells. It is during this type of cell division that gametes – sperm and egg cells Source: quora.com/Which-phase-of-the-prophase-of-Meiosis-1-doesare produced. During the first Figure 5 Recombination in Meiosis phase of meiosis, the homologous pairs of maternal and paternal chromosomes align. Then, the arms of the chromosomes temporarily fuse and overlap, causing a crossover. Crossovers result in recombination (see Fig.5) and the exchange of genetic material between the maternal and paternal chromosomes. This led the offspring to have different combinations of genes than their parents. Those genes that are located farther apart on the same chromosome have a greater likelihood of undergoing recombination, likely having a greater recombination frequency. By which means or conditions which evolution will not occur? The answer to this question is provided in the Hardy- Weinberg Principle which states that the allele frequencies in population will remain constant unless one or more factors caused these frequencies to change. When allele frequencies remain, constant there is genetic equilibrium, thus, the population will not evolve. Hardy-Weinberg Principle hold on to the following conditions: 1. No mutation. No new alleles are generated by mutation nor are genes duplicated or deleted. 2. Random mating. Organisms mate randomly with each other with no preference for particular genotypes. 3. No gene flow. Neither individuals nor their gametes will enter or exit the population. 4. Very large population size. The population should be effectively infinite in size. 5. No natural selection. All alleles that confer equal fitness tend to make organisms likely to survive and reproduce and those alleles with reduced fitness tend to have a dropping frequency from one generation to the next. When these conditions are met, the genetic equilibrium is maintained from generations to generations. The gene pool in a population remains pretty stable. All the five mechanisms of evolution mentioned above may act to some extent in any natural population. In fact, the evolutionary route of a given gene that is, how its alleles change in frequency in the population across generations may result from several evolutionary mechanisms acting at once. However, when the genetic equilibrium is not achieved or when at a stable state is disrupted, the population will continuously evolve.