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mitosis

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Lebanese University –
Faculty of Pedagogy –
Deanery
Practicum 2-Microteaching
Presented to :
Dr.Nadeen Fayyad
Prepared by :
Nasima Miah (ID: 5922)
After several weeks
How the body is able to repair these wounds ?
MATERIALS
Try to construct a model of what is occurring in each phase of mitosis (using the card
descriptions) using the pipe cleaners, beads, ping pong ball with yarn attached, and
large ring.
Prophase:
-Nuclear membrane disappears
-Centrosome duplicates and becomes 2 asters
-Achromatic spindle fiber appears
-Chromosome consist of 2 chromatids joined by
a centromere.
Metaphase:
-Spindle fibers from opposite ends of the cell
pull on chromosomes
-Chromosomes are aligned along the middle of
the cell.
Anaphase:
-Spindle fibers shorten and pull sister
chromatids to opposite ends of the cell
Telophase:
-Nuclear membrane re appear
-Aster becomes centrosome
- Achromatic spindle fiber disappear
-Formation of 2 daughter cells having each
chromosome consist of 1 chromatid
MITOSIS
Mitosis is the process of cell
division which occurs on
somatic cells.
It produces identical copies of
cells, where the mother cell
divides to produce two new
cells the daughters that are
genetically identical to itself
Mitosis consists of four phases :
prophase , metaphase ,
anaphase, and telophase.
INTERPHASE
Interphase is important for cell division because
it allows the cell to grow, replicate its DNA, and
make final preparations for cell division
Chromosomes are not clearly discerned in the
nucleus.
PROPHASE
-Chromatin in the nucleus begins to condense and
becomes visible in the light microscope as
chromosomes.
-Nuclear membrane disappears
-Centrosome duplicates and becomes 2 asters
-Achromatic spindle fiber appears
-Chromosome consist of 2 chromatids joined by a
centromere
In a normal human 2n = 46
chromosomes
But for simplification we will
use 2n = 4 chromosomes
METAPHASE
Spindle fibers align the chromosomes
along the middle of the cell nucleus.
This line is referred to as the
metaphase plate ( equatorial plate)
ANAPHASE
Centromere divides and Sister
chromatids separate and move
to opposite sides of the cell
forming (Polar Ascension).
TELOPHASE
Nuclear membrane re appear
-Aster becomes centrosome
- Achromatic spindle fiber disappear
-Formation of 2 daughter cells with 2n
chromosomes ,each chromosome consist of 1
chromatid
-cytokinesis or the partitioning of the cell may
also begin during this stage.
CYTOKINESIS
Cytokinesis is the physical process of cell division, which
divides the cytoplasm of a parental cell into two daughter
cells.
In cells such as animal cells, this fissure, or “crack,” is called the
cleavage furrow.
In plant cells, this structure is called a cell plate.
IMPORTANCE OF MITOSIS:
It ensures:
• the build up and growth of the
organism
• its cellular renewal
• the maintenance of its biological
identity.
SLIDES UNDER THE MICROSCOPE
Slide 3 :
Slide 1 :
Slide 5 :
Slide 2 :
Slide 4 :
ANSWERS : SLIDES UNDER THE MICROSCOPE
Slide 3 : prophase
Slide 1 : metaphase
Slide 5 : Telophase
Slide 2 : anaphase
Slide 4 : cytokinesis
Name: ________________________________
Date: _________________________________
Duration: 10 minutes
Match column A with column B
Column A
Column B
1_Anaphase
a. The nuclear membrane begins to disassemble
2_Telophase
b. Chromosomes are aligned along the middle of the cell
3_Metaphase
c. Spindle fibers shorten and pull sister chromatids to opposite
ends of the cell
4_Prophase
d. Cell membrane pinches in to completely surround each new
daughter cell.
5_Cytokinesis e. Nuclear membrane forms around each set of chromosomes.
Good work!
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