REGULATIONS 0F
GASTRIC SECRETIONS
Gastric acid secretion is regulated by three
local hormones: acetylcholine, gastrin, and
histamine. Of these three, acetylcholine
has the largest effect. Parietal cells, G
cells, and enterochromaffin-like cells are
stimulated by acetylcholine released in
response to vagus nerve simulation.
The process of gastric secretion can be
divided into three phases (cephalic, gastric,
and intestinal) that depend upon the primary
mechanisms that cause the gastric mucosa to
secrete gastric juice.