Name: Date: Period: Introduction to Genetics and Inheritance I. Homologous Chromosomes A. What do they have in common? 1. B. What makes them different? 1. II. Loci vs. Alleles A. A ________ is the position of a gene on a chromosome. B. An allele is a _________________________________. 1. “Two versions of the same gene.” III. Genotype vs. Phenotype A. A phenotype is the observable trait of an organism based on the _______________________________________________. B. A ______________ is a set of alleles that determines the expression of a particular trait. IV. Dominant vs. Recessive Alleles A. Alleles usually come in two variations: Name: Date: Period: 1. A _______________ allele expresses its phenotype regardless if its paired allele is identical or different. 2. A _______________ allele expresses its phenotype only when its paired allele is identical to it. V. Homozygous vs. Heterozygous A. Homozygous refers to _____________________________________. B. Heterozygous refers to _____________________________________. C. AA = ____________________ D. Aa = _____________________ E. aa = _____________________ For each of the genotypes below, determine the phenotype: Brown eyes (B) are dominant to blue eyes (b) 1. BB ____________________ 2. Bb ____________________ 3. bb ____________________ For each genotype, indicate whether it is heterozygous or homozygous: Name: Date: Period: 1. AA ___________________ 2. Bb ____________________ 3. QQ ___________________ 4. dd ____________________ How are genes passed down through gametes? I. Making Connections A. Looking at the genotypes, what are the possible gametes in references to the allele that can form? 1. 2. 3. B. In humans, sickle cell anemia is a disease caused by a mutation of a single locus gene which codes for an important blood protein. The allele for the normal protein (S) is dominant to that for the one causing sickle cell anemia. What gametes would be produced by an individual who suffers from sickle cell anemia? 1. Name: Date: Period: C. In areas of the very deep and damp southeastern United States, lives what is, for all intents and purposes, a giant flying cockroach known as a Palmetto bug. Assume that long antennae (L) are dominant to short antennae and that normal wings (N) are dominant to bent ones. What gametes will be produced by an individual that is homozygous dominant for antennae and heterozygous for wings? 1. D. In horses, the color black is due to a dominant allele (B) and brown color is due to the recessive allele (b). 1. What gametes would a homozygous dominant female produce? a) 2. What gametes would a heterozygous male produce? a) 3. What possible zygotes would they produce if mated? a) Name: Date: Period: I. Monohybrid Cross - using Punnett Squares A. Monohybrid Cross __________________________________________. B. The Father of Genetics: ___________________ C. Father of the Punnett Square: __________________ II. Solving Genetic Problems with Punnett Squares 1. Determine Allele Letters 2. Determine the Genotype 3. Draw Punnett Square Grid 4. Fill in possible gametes on each side 5. Run Cross (Fill in Grid) 6. ANSWER THE QUESTION! A. In dogs, wire hair (E) is dominant to smooth (e). In a cross of a homozygous wire-haired dog with a smooth haired dog. a. What will be the phenotype of the F1 generation? i. b. What would be the genotype of the F1 generation? i. c. What would be the ratio of wire-haired to smooth-haired dogs in the F2 generation? Name: Date: Period: i. B. The ability to curl your tongue up on the sides (T, tongue rolling) is dominant to not being able to roll your tongue. A woman, who can roll her tongue marries a man who cannot. Their first child has his father’s phenotype. a. What are the genotypes of the mother, father, and child? i. Name: Date: Period: I. Dihybrid Crosses A. Working with two genes B. For a giant cockroach, assume that long antennae (A) are dominant to short antennae and that normal wings (N) are dominant to bent ones. What gametes will be produced by an individual that is homozygous dominant for antenna and heterozygous for wings? You are not doing a punnett square just finding possible gametes. 1. C. Review Mendel’s experiment on pea plants! D. At the end of the experiment, what was the phenotypic ratio? 1. Name: Date: Period: I. Incomplete & Codominance A. Incomplete dominance is ______________________________________. B. Codominance is _____________________________________________. II. An example of incomplete dominance is _______________________________. III. An example of codominance is _______________________________________. A. A woman with blood type A is trying to figure which of three men she slept with is the father of her child with a blood type O. Which of the following is not the father? 1. JimBob (AO) 2. Paquito (OO) 3. J’waun (AA)