SILLIMAN UNIVERSITY
PHARMACY DEPARTMENT
DRUG DELIVERY SYSTEMS
LABORATORY
Activity No. 3
Calculations and Techniques Involved in Compounding Paper Powders
Name: _____________________________________________________________
Section: ______________________
Date: ____________________
Objective: At the end of this activity, students should be able to:
1. Measure accurately the amount of powdered drug (furosemide) required.
2. Demonstrate the proper techniques of preparing a paper tab reconstitution of oral drug.
Materials:
Furosemide 40 mg tab
Medicine box
Analytical Balance
Waxed paper
Scissors
Spatula
Mortar and pestle
Calculator
Ruler
Procedures:
1. Evaluate the Prescription below:
2. Base on your interpretation of the prescription, calculate the following:
a. Single dose of the drug
b. Dose per day
c. Total amount of the drug for the entire regimen
d. Total number of doses for the entire regimen
e. Total number of tablets required to supply the needed amount of the drug of the entire duration of
therapy.
Block and Divide Method Procedure:
1.
2.
3.
4.
Triturate tablets into desired powder form using mortar and pestle.
In a clean concrete tile, pour over the triturated powders and start to make a cake.
Using a spatula, shape the powder into cake form and make sure to flatten surface until clean finish.
Divide the cake powder into the desired portion. Using a ruler, measure each portion equally by making a
line of thin markings.
5. Using a thin spatula or cutter blade, slowly the portions of the powder and wrap.
6. Refer on the video presentation 8:03 minutes for the procedure of Block and Divide Method.
Results and Observation:
Patient and Drug Details
Age of Patient:
Name of the drug:
Strength of the Drug:
Dosage form of the Drug:
Drug Dose and Regimen:
Calculations Involved
Calculations
Single Dose
Daily Dose
Total Number of
Doses
Total amount of
drug needed for
the entire
regimen
Total Number of
tablets needed
Answer
Post Lab Questions:
1. Give the Pharmacology of furosemide and its usual indication for pediatric patients.
2. Give the essential components in prescription labelling for compounded paper tablet products.
Insert Photo of Compounded Finish Product here: