ACTIVE LEARNING TEMPLATE:
Medication
SAMUEL ADEOYE
STUDENT NAME______________________________________
Ceftriaxone
MEDICATION___________________________________________________________________________
REVIEW MODULE CHAPTER__28
__________
ANTIBIOTIC
CATEGORY CLASS__ANTIINFECTIVE;
_____________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action
Antibiotic that is semi-synthetic and belongs to the third generation
of cephalosporins. Binds to one or more penicillin-binding proteins
(PBP) found on the cell walls of susceptible organisms. This delays
the third and final stage of bacterial cell wall synthesis, resulting in
the bacterium's death.
(Lewis et al., 2016); ("Prentice hall nurse's drug guide," n.d.)
Therapeutic Use
It is used to treat bone and joint infections, gonorrhea and
intra-abdominal infections, meningitis and lower respiratory tract
infections, otitis media, pelvic inflammatory disease, Proteus
infections, septicemia, skin and soft tissue infections, and urinary
tract infections, as well as surgical prophylaxis, reducing or
eliminating infection. ("Prentice hall nurse's drug guide," n.d.)
Complications
Pruritus, fever, chills, pain, induration at IM injection site,
Abdominal cramps, pseudomembranous colitis, Genital
pruritus. (Lewis et al., 2016); ("Prentice hall nurse's drug
guide," n.d.)
Contraindications/Precautions
Hypersensitivity to cephalosporins and related antibiotics;
pregnancy (category B). (Lewis et al., 2016); ("Prentice
hall nurse's drug guide," n.d.)
Interactions
-Probenecid decreases renal elimination of ceftriaxone;
-Alcohol produces disulfiram reaction.
-AMINOGLYCOSIDES
(Lewis et al., 2016); ("Prentice hall nurse's drug guide,"
n.d.)
Evaluation of Medication Effectiveness
-Improved appetite, energy levels, and overall well-being
-Reduced infection sign and symptoms
-Poor performance on culture and adaptation tests
-Return to normal vital signs, including temperature
("Prentice hall nurse's drug guide," n.d.)
ACTIVE LEARNING TEMPLATES
Medication Administration
*IV Intermittent: Give over 30 min.
*Give deep IM into a large muscle.
*Moderate to Severe Infections:
Adult: IV/IM 1–2 g q12–24h (max: 4 g/d)
*Surgical Prophylaxis:
Adult: IV/IM 1 g 30–120 min before
surgery
Nursing Interventions
-Before beginning therapy, obtain a history of
hypersensitivity reactions to cephalosporins and
penicillins, as well as a history of other allergies,
especially to drugs.
-Look for induration and inflammation at injection
sites. Sites can be rotated.
-Look for symptoms of phlebitis at IV injection
sites (redness, swelling, pain).
-If diarrhea happens, check for fever: Both
should be reported as soon as possible.
Client Education
-Report any signs of bleeding.
-Report loose stools or diarrhea
promptly.
-Do not breast feed while taking
this drug without consulting
physician. (Lewis et al., 2016); ("
Prentice hall nurse's drug
guide," n.d.)