PICO Worksheet Define your PICO Components (OUTCOME MUST MATCH THE PROBLEM) Your question should be used to help establish your search strategy 1. Problem: Patient has history of past decay and active incipient caries in the mouth. Would a Rx fluoridated toothpaste be more effective than over the counter fluoride toothpaste 2. Intervention: Prevident 5000 and Colgate Anticavity Fluoride Toothpaste 3. Comparison: Remineralization of tooth decalcification to decrease chance of tooth decay 4. Outcome: An Rx of Prevident 5000ppm has a higher dose of fluoride and compared to colgate OTC toothpaste that will work better for incipient lesions when used properly at home. 5. Write out your question using the formula. (USE PICO COMPONENTS). For a patient with generalized incipient lesions, will Rx Prevident 5000 as compared to Colgate Anticavity toothpaste be more successful at remineralizing those demineralized tooth surfaces? Identify the Type of question. Circle one: Therapy/Prevention Diagnosis Etiology/Causation/Harm Prognosis 6. Identify the type of study to include in your search. Meta-Analysis Clinical Trial Cohort Study Cohort Study Study Other: Randomized Controlled Trial Case series or Case Report Systematic Review Practice Guidelines Case Control Literature Review 7. List main topics and alternative terms from your PICO question that can be used for your search. • best whitening method • Hydrogen peroxide vs B 8. List inclusion criteria - e.g., gender, age, year of publication 61 year-old caucasian female, stopped fluoride and does not use anything to treat her cavities. List where you plan to search, e.g., MEDLINE, PubMed, Cochrane Database, Other: Pubmed, cochrane database, medline.