PAGE 5-6 WHAT’S MORE 1. Aromatic Rings- 3 (F, W,Y)] Sulfur- 2 (C, M) Alcohol- 2 (S, T) Hydrocarbons- 6 (A, I, L, P,V,W) 2. Amino acid 3. Peptide bond 4. Fibrous 5. Fibrous 6. Globular 7. Fibrous 8. Fibrous 9. Fibrous 10. Both 11. Both 12. Both 13. Both 14. Globular 15. Central carbon (alpha carbon), carboxyl group, amino group, side chain (R) 16. Coordination of an organismʼs activities 17. Transport proteins 18. Defensive proteins 19. Structural proteins 20. Storage of amino acids 21. Contractile and motor proteins 22. Enzymatic proteins WHAT I HAVE LEARNED? Choose one protein classification according to function, then explain the importance of it. Elaborate what would happen if that certain protein doesn’t exist. You may give an example to help you explain it. Enzymatic proteins are biological catalyst that speeds up the reactions in biological systems. Enzymes are very important in all organisms as they catalyze different processes in the body like degradation of nutrient molecules, conservation and transformation of energy, and construction of biological macromolecules from simple precursors. Without enzyme, food cannot be digested as there are no proteins to enable digestion or degradation of nutrients into form that can be used by the body. Energy will not be used efficiently due to the lack of enzyme that will catalyze reactions. It will take huge amount of energy and longer time for any biological processes to take place without the enzymes. Furthermore, essential macromolecules such as lipids and nucleic acids cannot be formed. Page 1 of 11 One important role of enzyme is to convert chemicals we eat into something our body can take or also called toxin regulation. Example is the enzyme called alcohol dehydrogenase (ADH) which metabolizes the ethanol (found in alcoholic beverages) into toxic acetaldehyde. From there, the liver enzyme aldehyde dehydrogenase (ALDH) metabolizes acetaldehyde into acetate, a less toxic compound that breaks down into water and carbon dioxide. However, methanol toxicity is due to the absence of enzymes in our body that can process methanol the same way as ethanol. Enzyme that can regulate toxins are very important because of compounds like methanol that is exceptionally poisonous as it can cause blindness after consuming just less than 2 teaspoons, and a lethal dose is only about 2 tablespoons. Methanol is a byproduct of some alcoholic beverages processes. Page 2 of 11 PAGE 12-13 WHAT’S MORE A. Fill in the blanks a. 60% b. Sugar, starch and fiber (from fruits, grains and vegetables) c. Energy, digestive, metabolism/oxidation 4. Fat 5. Lactose 6. Simple 7. Glucose 8. Sucrose 9. Fructose 10. Glucose 11. Maltose 12. Lactose 13. Complex 14. Starch, starch B. 1. a, c, d, e 2. a. Fructose- monosaccharide b Ribose -monosaccharide c. Cellulose- polysaccharide d. Glucose- monosaccharide e. Sucrose- disaccharide f. Glycogen- polysaccharide g. Chitin- polysaccharide h. Starch- polysaccharide i. Maltose- disaccharide Page 3 of 11 WHAT I HAVE LEARNED? 1. Write the step-by-step drawing of Haworth projection for each of the following compounds: (a) α-d-Galactopyranose Step 1 Draw the skeleton of a Haworth projection Step 2 Draw the CH2OH group Step 3 Draw the OH group at the anomeric position Step 4 Draw the remaining groups Page 4 of 11 (b) α-d-Mannopyranose Step 1 Draw the skeleton of a Haworth projection d-Mannose Step 2 Draw the CH2OH group Step 3 Draw the OH group at the anomeric position Step 4 Draw the remaining groups Page 5 of 11 (c) α-d-Allopyranose Step 1 Draw the skeleton of a Haworth projection d-Allose Step 2 Draw the CH2OH group Step 3 Draw the OH group at the anomeric position Step 4 Draw the remaining groups Page 6 of 11 (d) β-d-Mannopyranose Step 1 Draw the skeleton of a Haworth projection d-Mannose Step 2 Draw the CH2OH group Step 3 Draw the OH group at the anomeric position Step 4 Draw the remaining groups Page 7 of 11 (e) β-d-Glucopyranose Step 1 Draw the skeleton of a Haworth projection d-glucose Step 2 Draw the CH2OH group Step 3 Draw the OH group at the anomeric position Step 4 Draw the remaining groups Page 8 of 11 (f) α-d-Glucopyranose Step 1 Draw the skeleton of a Haworth projection d-glucose Step 2 Draw the CH2OH group Step 3 Draw the OH group at the anomeric position Step 4 Draw the remaining groups Page 9 of 11 2. An example of carbohydrates is glucose which is the most abundant monossacharide. The primary role of glucose molecule is to act as source of energy or as a fuel. Plants and animals use glucose as a chemical energy that can be ‘burnt’ to release carbon dioxide, water and energy. Glucose is the most important substrate of cell metabolism and it is the carbohydrate fulfilling the task of being the energy transport system of the body. Page 10 of 11 PAGE 17 WHAT’S MORE 1. A hydrocarbon group 2. Unsaturated Saturated 3. unsaturated fatty acids 4. 1. Complex lipids 2. Simple lipids 5. Carbon, Hydrogen and Oxygen 6. Saturated fatty acids 1. All carbon–carbon bonds are single bonds 2. Straight chain hydrocarbon 3. Solid at room temperature Unsaturated fatty acids 1. With one or more double bonds in the hydrocarbon chain 2. Bent hydrocarbon chain 3. Liquid at room temperature 7. A 8. A WHAT I HAVE LEARNED? 1. Unlike other biomolecules such as amino acids, nucleic acids and proteins, the term “lipid” does not specify a particular chemical structure. There is general formula for most biomolecules but lipids are more chemically diverse. Compounds are categorized as lipids based on their greater solubility in organic solvents than in water. Page 11 of 11