Smoke inhalation, thermal lung injuries and CO intoxication Thermal injuries: injuries caused by inhalation of hot gases usually affects the upper airways, and in some cases, it will affect the distal airways caused by (Ability of upper airways to cool hot gases, Reflex laryngospasm and Glottic closure) Smoke inhalation injuries: damage caused by inhaling harmful gases. Such as, Irritating and toxic gases > Suspended soot particles > Vapors associated with incomplete combustion and smoke. The stages of smoke inhalation: Early stage (0-24 hours): tracheobronchial tree becomes more inflamed, resulting bronchospasm. This causes an overabundance of bronchial secretions to move into the airways, resulting in further airway obstruction Intermediate stage (2-4 days): there will be upper airway thermal injuries usually begin to improve. the pathologic changes deep in the lungs continue to be a problem Late stage (5days and longer): Infections resulting from burn wounds on the body surface. These infections often lead to sepsis and multiorgan dysfunction syndrome (MODS), Pneumonia and pulmonary embolism. long term effects in restrictive and obstructive lung disorders Anatomic alterations of thermal injuries: •Blistering •Mucosal edema •Vascular congestion •Epithelial sloughing Thick secretions •Acute upper airway obstruction Anatomic alterations of smoke inhalation: • Inflammation of the tracheobronchial tree • Bronchospasm • Excessive bronchial secretions and mucous plugging Decreased mucosal ciliary transport • Atelectasis • Alveolar edema and frothy secretions (pulmonary edema) • ARDS (severe cases) • Cryptogenic organizing pneumonia (COP) • Alveolar fibrosis, bronchial stenosis, bronchial polyps, bronchiolitis, and bronchiectasis (severe cases) Body surface burns: First-degree burn (minimal depth in skin): Superficial burn, damage limited to the outer layer of epidermis Healing time is about 6 to 10 days Second- degree burn (superficial to deep thickness of skin): Burns in which damage extends through the epidermis and into the dermis. Healing time is about 7 to 21 days Third-degree burn Third-degree burn (full thickness of skin including tissue beneath skin): Burns in which both epidermis and dermis are destroyed, with damage extending into underlying healing after 21 days or never occur without skin grafting Diagnosis: physical examinations, ABG, PFT (DLco will decrease), CXR (Usually normal in early stage -Pulmonary edema/ARDS in intermediate stage- Patchy or segmental infiltrate in late stage) Managements: 1-start with initial care of (Airway, Respiratory status, Cardiovascular status, the percentage of body burned, Depth of burns)2- IV line for fluids and medications 3- removing the separated clothing 4-soaking the remaining clothing before remove 5-covering the burn wound 6- infection control) Airway management- Bronchoscopy- Hyperbaric oxygen therapy- Treatment for cyanide poisoning-Antibiotic agents -Expectorants - Analgesic agents- Prophylactic anticoagulants. Respiratory care treatment protocols 1- Oxygen Therapy Protocol 2- Bronchopulmonary Hygiene Therapy Protocol 3- Lung Expansion Therapy Protocol 4- Aerosolized Medication Protocol 5- Mechanical Ventilation Protocol