BIOL 2113 – Chapter 12: The Nervous System and Nervous Tissue Study Guide Topic Identify the basic functions of the Nervous System Explanation 1.Sensation- environment around us. 2.Integration-association area 3.Response-motor functions Describe the components of the central and peripheral nervous system. Central nervous system – consists of the brain and spinal cord Peripheral nervous system –all the nerves that branch out from the brain and the spinal cord and extend to other parts of the body including muscles and organs Describe the structure of a neuron. Extending from the cell body are short, branched dendrites which receive chemical signals from other neurons or stimuli that initiate an electrical signal. ... The neuron consists of a cell body, dendrites, and an axon. Information flows from the dendrites to the cell body, and then on down the axon to its terminal. Discuss the functional types of neurons (may not be in the text). 1. Sensory neurons- the nerve cells that are activated by sensory input from the environment - for example, when you touch a hot surface with your fingertips, the sensory neurons will be the ones firing and sending off signals to the rest of the nervous system about the information they have received. 2. Motor neurons- are neuronal cells located in the central nervous system (CNS) controlling a variety of downstream targets. 3. Interneurons- central nodes of neural circuits, enabling communication between sensory or motor neurons and the central nervous system (CNS). They play roles in reflexes, neuronal oscillations, and neurogenesis in the adult brain. Discuss the structural types of neurons. 1. Unipolar neurons- one process, called a neurite, extends from the cell body 2. Bipoloar neurons- has two extensions (one axon and one dendrite). 3. Multipolar neurons- possesses a single axon and many dendrites (and dendritic branches), allowing for the integration of a great deal of information from other neurons. Identify and discuss the glial cells of the CNS. 1.Atrocyte- star shaped connect neurons to blood vessels Topic Explanation 2.Microglial- phagocytic 3.Ependymal- Line cavities containing cerebro spinal fluid 4.Oligodendrocytes-myelinate axons (coats axon) Identify and discuss the glial cells of the PNS. 1.Sattelite Cells-support ganglia(cluster of cell bodies) 2.Schwann Cells- Myelinate axons in pns Define synapse and describe the events that occur at the synapse. A junction that mediates information transfer from one neuron to the next or from a neuron to an effector cell Describe an action potential, its generation, and An action potential is generated in the body of the neuron and propagated through its transmission. axon. ... Because of this, an action potential always propagates from the neuronal body, through the axon to the target tissue. The speed of propagation largely depends on the thickness of the axon and whether it's myelinated or not. Discuss the “all-or-none” principle of action potentials. The all-or-none law is the principle that the strength by which a nerve or muscle fibergggyu0-rev responds to a stimulus is independent of the strength of the stimulus. ... If that stimulus exceeds the threshold potential, the nerve or muscle fiber will give a complete response; otherwise, there is no response. Describe the following: Excitatory Postsynaptic Potential (EPSP) – postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential. ... When multiple EPSPs occur on a single patch of postsynaptic membrane, their combined effect is the sum of the individual EPSPs. Inhibitory Postsynaptic Potential (IPSP) – kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential Topic Explanation Spatial summation – the effect of triggering an action potential in a neuron from one or more presynaptic neurons. This occurs when more than one excitatory postsynaptic potential (EPSP) originates simultaneously and a different part of the neurone. Temporal summation – occurs when a high frequency of action potentials in the presynaptic neuron elicits postsynaptic potentials that summate with each other. Discuss neuron regeneration (not in textbook). regeneration and repair in the nervous system is a process by which damaged tissue undergoes regrowth or renewal, leading to eventual restoration of nervous system function. This process happens more readily with axons, synapses, neurons and glia in the peripheral nervous system. Discuss the following common neurotransmitters (be sure to identify as excitatory or inhibitory as well as general type of chemical category): Acetylcholine – excitatory neurotransmitter secreted by motor neurons that innervate muscle cells, basal ganglia, preganglionic neurons of the autonomic nervous system, and postganglionic neurons of the parasympathetic and sympathetic nervous systems. Its main function is to stimulate muscle contraction. Serotonin – inhibitory neurotransmitter that is involved in emotion and mood, balancing excessive excitatory neurotransmitter effects in your brain. Dopamine – both excitatory and inhibitory. Dopamine helps with depression as well as focus, which you will read about in the excitatory section. DOPAMINE is our main focus neurotransmitter. Norepinephrine and epinephrine – excitatory action are acetylcholine, norepinephrine, and epinephrine while GABA is the major inhibitory neurotransmitter. Describe these disorders (you may have to research beyond your text). Multiple sclerosis – potentially disabling disease of the brain and spinal cord (central nervous system) the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Guillain-Barre – rare disorder in which your body's immune system attacks your nerves. Weakness and tingling in your extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing your whole body. Alzheimer’s disease – degenerative brain disease and the most common form of dementia. Dementia is not a specific disease Topic Explanation Parkinson’s disease – progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand Creutzfeld-Jacob disease – disease is a degenerative brain disorder that leads to dementia and, ultimately, death. Symptoms of Creutzfeldt-Jakob disease (CJD) can resemble those of other dementia-like brain disorders, such as Alzheimer's. But Creutzfeldt-Jakob disease usually progresses much more rapidly.