10/12/20 Genitourinary Cancers Part 2 1 Outcomes Related to this Lesson u Correlate the epidemiological factors, pathophysiology, clinical manifestations, and nursing management of clients experience the following genitourinary cancers: u Differentiate pertinent diagnostic studies and lab findings used to confirm the diagnosis of genitourinary cancers u Compare collaborative treatments used for the management of genitourinary cancers u Prioritize nursing interventions for managing genitourinary cancers u Design a discharge teaching plan that includes dietary and lifestyle considerations for clients with genitourinary cancers • Formulate a comprehensive teaching plan for clients experiencing or recovering from specified genitourinary cancers • Perform and document in the EHR a physical examination of clients affected by genitourinary cancers • Utilize SBAR to communicate client information to the supervising nurse u Breast Cancer u Uterine/Endometrial Cancer 2 Breast Cancer 3 u Definition of Disease process u Pathophysiology/Etiology u Review this information in the Lewis text and your pathopharm text. Tumors of the breast Can effect both men & women 2nd most common cause of cancer 2nd most common cause of death Incidence is slowly decreasing Breast cancer survivors are largest group Etiology & risk factors for women - family hx, environmental factors, genetics, early menarche, late menopause, 60 or older Most who develop have no identifiable risk factors Hormonal regulation is related to breast cancer development - poorly understand Combined hormone therapy - can increase risk of breast cancer - small increase risk (larger tumor size at diagnosis) High tumor stage as diagnosis Estrogen alone may increase risk after 15 years of taking it Modifiable - excess weight gain during adulthood, sedentary lifestyle, smoking, excess dietary fat intake, obesity, excess alcohol intake, environmental factors, radiation exposure, 10% genetic Genetic link is stronger - family member had a hx of ovarian cancer was premeno - bilateral breast cancer 1 First degree family member of breast cancer - risk doubles 10/12/20 Breast Cancer u CLINICAL MANIFESTATIONS Lump that has not been present before Thickening or mammographic abnormality in the breast Rate of lesion growth varies Palpable - feels hard, irregular, borders are indistinct Not going to move, painless Nipple discharge or retraction of nipple Dippling of the tissue - or tissue may be red or swollen 4 Breast Cancer u Diagnostics 5 Breast Cancer u 6 Interprofessional Care Radiologic studies Mammogram Digitial mammography - more accurate in younger women 3d mammography Ultrasound in conjuction with mammogram if abnormality is found MRI Biopsy - high risk - fine needle aspiration of lung Vacuum assisted biopsy - very large needle introduced tissue is vacummed Exigency biopsy - remove mass itself Wide range of treatment options Critical pt & HCP work together to make decisions Treatment plan depends on prognostic Stage & biology of cancer Surgical intervention, radiation, drug, hormone, immunotherapy, targeted therapy Surgical procedures for operable breast cancer: Breast conservation therapy (lumpectomy) MUST HAVE Radiation following to entire breast Segmental mastectomy Mastectomy with or without reconstruction Lumpectomy - removing tumor with a margin of normal tissue around it If chemo - prior to radiation therapy 2 10/12/20 Breast Cancer u Nursing Interventions 7 Reducing risk factors Healthy weight, exercise, limiting alcohol, eating nutritious foods, low fat diet, no smoking, complying with screening guidelines Risk reduction options for high risk pts: Genetic testing- consider prophylactic ovary and tube removal & breast surgery Assist to be able to cope with the diagnosis Pre and post op pain control and care Mobility restrictions and post op exercises Recovery period - follow up Premedicate prior to exercises Drain care is needed and taught Restoring arm function on affected side is a key nursing goal - reach for recovery - support group Report symptoms post op - fever, inflammation, eryhtema, unusual swelling Garment that have foam breasts within them Psychosocial support is a must Offer coping skills Breast Cancer u Nursing Interventions 8 Breast Cancer u 9 Complications Recurrence and metastasis Local - skin Regional - lymph nodes Distance - bones, brain, lungs, liver, bone marrow, spinal cord Lymphedema - accumulation of the lymph in the soft tissue of the affected mode Lymph node sampling or radiation therapy Axillary nodes cannot return lymph fluid to the central circulation because they have been removed or damaged - obstructive pressure on veins Post breast therapy pain syndrome - nerve injury to chest wall during surgery Chemo complications - can be mild to debilitating pain tingling aching numbness edema itching Treatment - NSAIDS, low dose antidepressents, antiseizure drugs Phantom breast pain 3 10/12/20 Breast Cancer u Patient Education 10 Breast Cancer u Patient Education 11 Uterine/Endometrial Cancer 12 u Definition of Disease process u Pathophysiology/Etiology Yearly mammograms Start age 45 45-54 YEARLY 55 - start to get every 2 years Continue screening as long as overall health is good Clinical breast exams annually Increased risk - earlier 3d screening Family hx - breast MRI, more frequent clinical breast exams Self breast exams - self awareness Normal look & feel of breast Return demonstration with pt Drain care, report symptoms fever, inflammation, swelling Continue with follow up routine Ongoing monitoring and self care Prevent and reduce lymphedema No BP, vein, injections on that side Arm should not be dependent for long periods Preventing infections, burns, compromised circulation of that arm Exercise - normal weight Special garment choices, breast prosthesis Breast cancer survivorship care - 1-4x a year HCP for first 5 years Annually after that Reccurence is usually at surgical site Do mammograms Breast cancer is men is rare but does occur Same treatments - may have body image issue Uterine lining or the endometrial lining where cancer arises Most common gyne cancer Low mortality rate when diagnosed early 88% survival rate Reduced riisk - pregnancy, BC pills, IUD, physical exercise Most tumors are adenocarcinomas - can invade the myometrium and regional lymph nodes if not diagnosed early Metastatic sites - lung, liver, brain & bone Prognosis depends on tumor size, cell type, degree of invasion, and metastasis Risk factors - exposure to estrogen - estrogen therapy without progesterone therapy, obesity, adipose cells store estrogen, age, early menarche, late menopause, smoking, diabetes, family hx of hereditary 4 10/12/20 Uterine/Endometrial Cancer u Clinical Manifestations Early - abnormal uterine bleeding Any women over 35 - bleeding inbetween periods with uterine cancer until proven otherwise NEEDS TO BE EVALUATED Bleeding after menopause - likely cancer Dysuria, dyspareunia (painful intercourse), weight loss, pelvic pain 13 Uterine/Endometrial Cancer u No routine tests Diagnosed early due to post menopausal bleeding Endrometrial biopsy - main test Diagnostics 14 Uterine/Endometrial Cancer u Interprofessional Care Total hysterectomy Bilateral salpingo-oophorectomy lymph node biopsies radiation can be done for local or distanced Chemotherapy, hormonal therapy - for advanced or recurrent 15 5 10/12/20 Uterine/Endometrial Cancer u Nursing Interventions Family hx of cancers of uterine, stomach, liver, kidney, brain, skin, ovarian, colorectal Hx of 2 of these cancers means a referral for genetic testing - can indicate lynch syndrome Assess for pain & provide meds as ordered Infection at surgical site Fever, wound care Early ambulation 16 Uterine/Endometrial Cancer u Patient Education Report signs and symptoms of infections Excessive bleeding Scant bleeding after surgery - expected Not recommended to drive 4 weeks after surgery Post op appointments Pain management - no opiods after 3 days NSAIDS should be ok Stool soft - to prevent straining Will be infertile - pt needs to know 17 6