CC: Basal ganglia ICH HPI: 33 y.o. female patient with hx of Moya Moya s/p Right STA-MCA onlay bypass in 20/18 who presents after being found down. LKN of 0300. Her mother found her on the floor at 1000 with L hemiplegia. EMS was called. Work up in ED reveled CT head demonstrated a large R basal ganglia hemorrhage with mass effect, IVH, as well as trace blood in the R vent 3 and 4. Reported episode of systemic hypertonia - resolved after 10 seconds, unclear if seizure. She was arousable but having episodes of being sonorous and had significant dysarthria. She required aggressive sternal rub to arouse. In the ED, she was given keppra as well as mannitol. Due to her inability to protect to airway and declining mental status, she was emergently intubated. Time of onset: 0300 LKN PMH: Anxiety Asthma Depression Hx of idney stones Moyamoya Narcolepsy PSH: Cranial angio - 12/2018 Bilat cerebral sarotid angio Encephalo-Myo-Synangiosis (indirect cerebral bypass) R craini 6/2018 Home Medications: Lipitor 10 mg daily B vit daily Co enzyme Q10 Gabapentin 300mg/QHS 100mg/QAM Inpatient meds: Keppra 1000 BID Mannitol 75 x 1 Continuous Infusions: PRN Meds: Allergies: NKDA Family History: None of relevance to acute dx / CC of concern ROS: Unable to obtain due to clinical condition, (intubation, encephalopathic) PHYSICAL EXAM Neuro: GCS: E 2 V 2 M 6 Higher cortical function: Eyes open to noxious stim, requires repeated stimulation to arouse, answered name, age, hospital, would not participate in any further language testing. L sided neglect. Intermittently followed commands on the R side. Cranial nerves: Pupils equally reactive to light and accommodation, sluggish. Visual fields no blink to threat on the L side. R gaze deviation, no L gaze. L facial droop. Speech very dysarthric. Motor/Sensory: Normal bulk and decreased L-sided tone. Drift on the R side. L UE extension, L LE triple flex in response to noxious stim. Reflexes: L toe extensor response to plantar stimulation. Coordination: unable to assess due to encephalopathy Gait: deferred NIHSS: 1a. Level of consciousness: 2 1b. LOC questions: 0 1c. LOC commands: 0 2. Best gaze: 2 3. Visual: 2 4. Facial palsy: 2 5a. Motor arm (left):3 5b. Motor arm (right): 1 6a. Motor leg (left): 3 6b. Motor leg (right): 1 7. Limb ataxia: 0 8. Sensory: 1 9. Best language: 1 10. Dysarthria: 2 11. Extinction and inattention:2 Total: 22 Remaining systems: Temp 38.1; BP 138/75; HR 79; RR 22, Sats 97 % RA General: Ill appearing, obese HEENT: normocephalic, atraumatic, oropharynx pink and moist, dentition intact Neck: supple CV: +S1 +S2, RRR, no murmurs, rubs or clicks; symmetric, regular pulses Lungs: clear throughout to auscultation, sonorous at times Abd: soft, nontender, normal bowel sounds Ext: (-) C/C/E or deformity Skin: warm, dry, intact joints without deformities PLAN/ASSESSMENT: 33 y.o. female patient presented with L sided weakness, exam findings of L HH, encephalopathy, L hemiplegia, CT head with basal ganglia ICH. Etiology is likely related to Moya Moya given that her surgery was on the R side in the past and no evidence of malignant HTN at presentation. Neurologic: ICH, IVH, Acute metabolic encephalopathy, Cerebral edema, Compression of the brain, Moya Moya, s/p EDAMS, Narcolepsy, Depression, anxiety CT at admit shows 7.6 cm parenchymal hematoma centered in the right putamen/posterior frontal lobe with associated local mass effect, 6 mm right to left shift, and intraventricular hemorrhage as detailed above. No clear tonsillar herniation or uncal herniation present CTA:1. Chronic high-grade stenosis versus occlusion of the distal right M1 segment with ipsilateral lenticulostriate and PCA collaterals as previously discussed as well as mild diffusely decreased perfusion in the right MCA territory, similar to the prior. Small STA branch serving the STA-MCA anastomosis does not clearly show filling on CTA; consider conventional angiography. 2. Otherwise normal intracranial vasculature Plan: - Admit to NCCU - Case discussed with MDs, plan for OR for hematoma evacuation and EVD placement – going down within hours - Anticoagulation reversal: NA - Hyperosmolar therapy: s/p mannitol x1, will determine need for additional hypertonics after OR - Neuro checks every 2 hours for potential neuro decline related to rebleeding, hematoma expansion, or hydrocephalus - PT/OT/SLP to evaluate and treat when appropriate - keppra 500mg q 12 hrs - restart lamictal, gabapentin after enteral access - hold ritalin and provigil for now - hold cymbalta (unable to go down OG tube) CV: NSR, HLD Plan: -Continue hemodynamic monitoring. - Blood pressure management: Keep SBP <160 with labetalol or nicardipine drip as needed. - continue atorvastatin Respiratory: Ventilator dependent Data: CXR: EET at appropriate place Diagnoses: Acute respiratory failure due to inability to protect airway Plan: - Ready to wean: No - Ready to extubate: No - HOB >30 degrees - Maintain oxygen saturations > 92% - VAP prevention protocol F/E/Renal/GU: HypokalemiaHx of kidney stones K 3.8 CL 107 CO2 19* BUN 25* CREA 0.93 CALCIUM 10.1 Plan: - electrolyte replacement protocols - IVF: bolus with mannitol (x1 complete), continue IVF Endocrine: Risk of poorly controlled blood sugars r/t critical illness Plan: -Glucose Goal 90-180, correction factor insulin GI/Nutrition: Plan: - prevent constipation/avoid straining, Bowel care: prns - antiemetics PRN - OG tube - swallow eval and speech when appropriate Heme/Coags: anemia, baseline PTT 24.9 INR 1.0 HGB 9.9* HCT 31.5* PLT 514* Plan: - type and screen completed, trend labs, transfuse if symptomatic or if hbg below 7 ID: tmax 38l.3 , WBC12.6*, Leukocytosis (most likely refractive) Plan: - Monitor for fever, temperature goal < 38C to prevent increased cerebral metabolic demand. Skin: no issues Plan: -monitor, frequent turning and peri care Prophylaxis: DVT: SCDs only at this time - to reassess after OR GI: Pepcid, PRN Zofran / reglan, maintain NPO tuntil post op Social: Mother came with to ED, will return later after going home to pick uo husband Code status: full