Watch the following video about organic compounds and answer the following questions. https://www.youtube.com/watch?v=nt9u7CfVoc4 1. Name the four molecules of life and their functions. 2. Name the elements found in the molecules of life. 2 of 30 © Boardworks Ltd 2008 Research and share What are biomolecules? Organic compounds are chemical substances that: Make up organisms Help organisms carry out life processes All contain the elements carbon & hydrogen Carbon is the major element Something for you to do? In groups, find out 3 significance of carbon. I. Carbon is the most important element in living things because of its special properties. A. Carbon can form bonds with itself. B. Carbon can form molecules with long chains/ rings of atoms. C. Many molecules found in living things (like DNA, sugars, fats, and proteins) are LARGE molecules containing chains of carbon. Six elements form most molecules in living things: Phosphorus Nitrogen Carbon Hydrogen Oxygen Sulfur Please Never Call Her On Sunday a molecule that is produced by a living organism. present in organisms essential to biological processes, such as cell division, morphogenesis, or development. Carbohydrates are made from the elements carbon (C), oxygen (O) and hydrogen (H), bonded on a ration of 1:2:1. Something to think about Provide 3 functions of carbohydrates in living organisms. They are used to: store energy – starch in plant cells; glycogen in animal muscle cells provide energy – during cellular respiration in the mitochondrion provide structure and protection –through cellulose They are used to: store energy – starch in plant cells; glycogen in animal muscle cells provide energy – during cellular respiration in the mitochondrion provide structure and protection – cell wall in plant cells. Monosaccharides are single ring structures Glucose is the basic building block of all carbohydrates. Examples glucose (C6 H12 O6), fructose (C6 H12 O6), galactose (C6 H12 O6) Polymers: large molecules are made up of long chains of single units called polymers. The single units are called monomers. Two monosaccharides bonded together form a disaccharide. One water molecule is removed to form a disaccharideCondensation reaction/ Dehydration synthesis Sucrose Maltose Lactose (table sugar) (dough sugar) (milk sugar) Glycosidic bond Glucose + glucose maltose + water Glucose + fructose sucrose + water Glucose+ galactose lactose+ water More than two monosaccharides bond together by condensation reaction to form a carbohydrate called a polysaccharide May contain a thousand monosaccharides They store energy (starch) and form structural tissues (cellulose, exoskeletons) Polysaccharides are water insoluble Starch is a form at which glucose is stored in a plant. When the plant needs the energy. Starch is broken down and glucose is released through Hydrolysis, i.e during cellular respiration Monosaccharides Formula Where found Fructose C6 H12 O6 Fruits Glucose Galactose , or ribose C6 H12 O6 Galactose: C6 H12 O6 From digestion of other carbohydrates Galactose: milk Ribose: C5H10O5 Ribose: DNA, RNA Disaccharides Formula Where found Sucrose C12 H22O11 Table sugar Lactose C12 H22O11 Milk Maltose C12 H22O11 Malt sugar Polysaccharides Where found Function Starch Potatoes Used by plants to store energy Glycogen In human liver cells Used by animals to store energy Cellulose Cell walls of plants Used by plants to form rigid walls around cells Chitin Exoskeleton of insects Used by some animals to form an external skeleton 1. 2. 3. 4. 5. 6. 7. 8. Name the 4 main elements that make up 95% of an organism. Name the monomers of carbohydrates. Name the 4 types of bonds carbon can form. What are macromolecules? What elements make up carbohydrates & lipids (symbols)? Differentiate between a monosaccharide, disaccharide and a polysaccharide. Differentiate between a glycosidic bond, dehydration synthesis and condensation reaction. Name the sugar molecules that form maltose, sucrose and lactose. In pairs, complete the following questions. 1. State the difference between a monosaccharide, disaccharide and polysaccharide. 2. Complete the following reactions glucose + glucose ---------- maltose + water glucose ---------- + water ---------- + fructose sucrose Glucose+ galactose ----------------------- lactose+ water Carbon, Hydrogen, Oxygen, Nitrogen 2. Monosaccharides (glucose, galactose, fructose). Main monomer is glucose. 3. Single bonds, double bonds, triple bond (sharing of 6 electrons). 4. Macro-molecules: molecules required in large quantities by living organisms. 5. CHO 6. Monosaccharide: single ring sugar molecules e.g glucose; Disaccharide: two monosaccharides bonded together form a disaccharide. Polysaccharide: More than two monosaccharides bonded together 1. 7. Glycosidic bond: type of covalent bond that joins a sugar molecule to another group, which may or may not be another carbohydrate. Dehydration synthesis and condensation reaction: a process of joining two molecules, or compounds, together by removing water Hydrolysis is a chemical process in which a molecule of water is added to a substance to split it into two parts. 8. Glucose + glucose maltose + water Glucose + fructose sucrose + water Glucose+ galactose lactose+ water Glycosidic bond: type of covalent bond that joins a sugar molecule to another group, which may or may not be another carbohydrate. Dehydration synthesis and condensation reaction: a process of joining two molecules, or compounds, together by removing water Hydrolysis is a chemical process in which a molecule of water is added to a substance to split it into two parts. Diabetes: Type1: A chronic condition in which the pancreas produces little or no insulin Type 2: the body either doesn't produce enough insulin, or it resists insulin. Treatments include diet, exercise, medication and insulin therapy. https://www.youtube.com/watch?v=nt9u7CfVoc4 - song https://www.youtube.com/watch?v=jQi84TnstI4 – carbohydrates https://www.youtube.com/watch?v=BVxeeiR7JB0 – lipids Skip 2:58- 5:31; 7:45- 9:15 https://www.youtube.com/watch?v=HSCUAjZQhXI – proteins ****Take note of the 20 amino acids for Grade 12 Protein Synthesis Contain carbon, hydrogen, and oxygen E.g fats, waxes and oils Lipid molecules consist of 1 glycerol & 3 fatty acids Other types of lipids can contain additional molecules. Properties of lipids Are they soluble in water???? Soluble in alcohol All lipids are hydrophobic Made up of saturated and unsaturated fatty acids. What is the difference between the two? 1. Unsaturated fats – liquids at room temperature – mainly plant fats eg. olive oil, sunflower oil 2. Saturated fats – solids at room temperature – mainly animal fats eg. fat on red meat, butter A diet high in saturated fats cause the formation of cholesterol in the blood which clogs arteries (artherosclerosis) – can lead to heart attack Lipids may consist of fatty acids alone or in combination with other compounds; several types of lipids consist of fatty acids combined with a molecule of alcohol: Triglycerides are the main form of stored energy in animals (fat) Phospholipids membranes surrounding the cells of all organisms Steroids (or sterols) have several functions. The sterol cholesterol makes up cell membranes and plays. Other steroids are male and female sex hormones Rich source of energy Storage of reserve energy eg. peanuts & seeds Structural component of cell membranes – phospholipids Provides insulation beneath the skin eg. blubber in seals Waterproofing material – waxes in insect & plant cuticles Protects major organs eg. heart, kidneys Type of Lipid Triglycerides Saturated Unsaturated Phospholipids Steroids Characteristics Main form of stored energy in animals Where found vegetable oil (typically more unsaturated) animal fats (typically more saturated) Animals use these to store energy Form straight chains b/c carbon atoms are bonded to as many H atoms as possible; store energy in compact form; solid at room temperature Form bent chains b/c Plants use these to store energy some C atoms are not bonded to as many H atoms as possible; store energy; liquid at room temperature Major component of Liver, peanuts cell membranes Serve as chemical found in plants, animals, and fungi messengers and have other roles Answer the following questions. 1. State four functions of lipids 2. Name the monomers of lipids 3. Differentiate between saturated and unsaturated fatty acids 4. What are trans fats? Provide an example 5. Explain the function of lipase 6. Where is lipase secreted in the human body 7. What solution is released by liver to break down lipids? 8. Which fats are healthier between saturated and unsaturated fats? Explain your answer. Contain C, H, O, N and P Consist of building blocks called nucleotides 1. DNA – deoxyribonucleic acid 2. RNA – ribonucleic acid Biological Importance - DNA carries and transmits genetic information - DNA & RNA control the metabolic activities of the cell eg. protein synthesis Contain C, H, O and N Some also contain P, S and Fe Consist of long chains of amino acids The number and sequence of amino acids determines the characteristics of a particular protein There are 20 different types of amino acids There are 20 different types of amino acids The sequence of amino acids determines the type of protein The bond between amino acids is known as a peptide bond. Peptide bond There are 20 different types of amino acids Dipeptide bond- two amino acids linked by a peptide bond. Tripeptide bond- the bond between 3 amino acids Polypeptide bond – the bond between many amino acids Proteins are 51+ amino acids linked by polypeptide bond Peptide bond Biological Importance : Forms body materials eg. Muscle, skin, hair, nails Enzymes and hormones are proteins Transport eg. haemoglobin transports oxygen in blood Protects body eg. Forms antibodies, fibres for blood clots Study the following diagram and answer the questions. 1. Differentiate between organic and inorganic compounds 2. Identify the type of organic compound represented by A, B and C, respectively. 3. Name the compound formed by the two glucose molecules on A. 4. Identify the type of bond indicated by X. are globular proteins Biological functions biological catalysts i.e. speed up the rate at which metabolic reactions occur in living organisms maintains reactions at an optimum rate catalyze the synthesis and breakdown of molecules For a reaction to happen it needs activation energy Enzymes lower the activation energy of a reaction Therefore accelerating the reaction. Chemical reactions in living cells are known as metabolic reactions. There are two types of metabolic reactions: Anabolic reactions Catabolic reactions For a reaction to happen it needs activation energy Enzymes lower the activation energy of a reaction Therefore accelerating the reaction. Disaccharides maltase maltose + water---------- glucose + glucose sucrase sucrose + water ----------- glucose + fructose lactase lactose + water ---------- glucose + galactose Polysaccharides amylase starch+ water ---------- maltose During digestion, complex molecules are broken into simpler molecules by using water. This catabolic process is known as HYDROLYSIS Lipid lipase Lipid + water ---------- 3 fatty acids + 1 glycerol Protein Protease proteins+ water ---------- smaller polypeptides, amino acids e.g. pepsin A substance that an enzyme acts on is called a substrate. A substance formed during the reaction is the product. Enzymes are substrate specific Enzymes remain unchanged in a chemical reaction maltase maltose + water---------- glucose + glucose Lock & key theory 1. 2. 3. 4. 5. 6. Identify the parts numbered 1-5. Define enzyme. Is the reaction illustrated above anabolic or catabolic? Provide a reason for your answer. What is the function of part numbered 2? Which numbered part is specifically affected by change in pH? Give an explanation of how part numbered 2 is affected by changed in pH. Enzymes 1. 2. 3. 4. 5. are sensitive to temperature and pH function best (optimum rate) at an optimum temp (30◦C-40◦C) & pH (substrate specific) exposure to extreme temp (45◦C) & pH denatures enzyme low temperatures inactivate enzymes Can be used over and over again 1. ‘Biological’ detergents – contain protein-digesting enzymes (proteases) to break down stains eg. blood, sweat, gravy, egg yolk 2. Brewing industry – beer making 3. Dairy industry – cheese making 4. Food industry – fruit juices 5. Baking industry –bread making 1. 2. 3. 4. State the optimum temperature for the enzyme. What amount of food is broken down at 25◦C? Give an explanation for the shape of the graph between 5◦C and 35◦C. State 4 properties of enzymes. The graph below shows the effect of temperature on enzyme activity The graph below shows the effect of temperature on enzyme activity 1. 2. 3. State the optimum temperature for the enzyme. State the enzyme activity at: a. 20◦C b. 40◦C c.50◦C Briefly explain what happens to the enzyme activity once it reaches its optimum temperature Make use of a labelled diagram to prove that enzymes are substrate specific. Contain C, H, O and N, also S, P – complex organic compounds Required in small quantities for normal growth and development in animals 1.1 List the nutrient that is required for : a. developing muscle tissue b. maintaining good eye-sight c. maintaining salt-water balance 1.2 State the deficiency disease if there is a lack of a. vitamin B1 b. iron 1.3 If a person ate 4 slices of bread for lunch calculate the amount (in g) consumed of the following : a. Protein b. Sugar The table below indicates the nutritional information on the packaging of a loaf of brown bread. Composition (elements present) Carbohydrates Lipids Nucleic acids 1 Function 1 Example Monomer Composition (elements present) Carbohydrates Function Examples Monomer 1. 2. 3. 4. Which of these food types are least suitable as a source of insulation? Give a reason. Which of these food types are most suitable for structural growth? Give a reason. Give a reason why food type C is the richest source of energy. What percentage of food type B is fat? 1. 2. 3. Name the main component of food type C. List 3 nutritional function of the component mentioned in no.1 What type of food (A, B, C or D) will be the most beneficial to a person that lives in a very cold place such as Antarctica? Give a reason. 1. 2. 3. a) b) c) Identify each compound (A, B & C). Give a reason for your answer. Name the monomers of compound C. Which compound (A, B or C).. is involved with the formation of the large, insoluble compounds that are needed for the formation of plant cell wall? may form part of enzyme? Is used as main energy source in respiration? 1. a) b) c) d) Give the names of the following: Enzyme A Compound B Molecule C Enzyme X