1. What does CHD stand for? Coronary Heart Disease 2. What is coronary heart disease (use these slides, don’t google the answer!)? Coronary heart disease (CHD) is when the arteries that supply the heart muscle cells become blocked so the blood flow to the heart muscle cells is reduced. 3. Give three risk factors (things about your lifestyle) that will increase your chance of getting CHD? Smoking, High fatty or high salt diet, high alcohol, obese 4. Who is more likely to suffer with CHD: a man or a woman? Men 5. Is CHD only caused by lifestyle choices? No there is a genetic factor and the risk increases as you get older. S3a.2 continued. Today we are going to focus on looking at the advantages and disadvantages to different treatments of cardiovascular disease (cardio means heart and vascular means blood transport system so veins and arteries). We will then look at exam technique in answering these questions. Copy out this table of advantages and disadvantages of treating coronary heart disease. I have added in an extension one at the end for the very keen among you – you would need to google artificial blood advantages and disadvantages to fill it in! Treatment Advantage Disadvantage Drugs – statins Stents Heart transplant Replacement valves Artificial blood Carried on next page Evaluate questions and answers. Remember, in science, when you evaluate something you compare the advantages and disadvantages AND give a final conclusion about which is better using a reason from you answer. Have a go at this question. Read the exam technique advice underneath first. 1. People can be treated for cardiovascular diseases with statins or aspirin. Information about these two drugs is given in the table. STATINS Statins are only available on prescription from doctors. ASPIRIN Aspirin can be bought over the counter. The cost of treating patients with statins can vary between £150 and £500 per year, depending on the type of cardiovascular disease being treated. Treatment with aspirin costs up to £15 per year. In studies, 30 000 patients were monitored over several years. Statins were found to reduce the rate of nonfatal heart attacks by about 30%. In a study of 1000 patients aspirin was found to reduce the risk of non-fatal heart attacks by 31%. Approximately 0.1% of the patients suffered serious muscle damage and 0.01% suffered kidney failure. Aspirin was found to cause bleeding of the stomach in around 0.5% of patients and there was a slightly increased risk of poor blood clotting at cuts Evaluate the use of statins or aspirin for the treatment of cardiovascular diseases. In your answer you should: • give your recommendation • use information from the table to support your recommendation by making comparisons of the two drugs. Exam technique: For each row of the table, highlight which drug is the better option. Use this in your answer. Remember to use connecting words such as ;whereas’, ‘however’, ‘on the other hand’ and to give your conclusion at the end. A good way to finish your answer with your conclusion is to write ‘overall, I think … are best at treating cardiovascular diseases because…’ ______________________________________________________ ______________________________________________________ _______________________________________________________ _______________________________________________________ _______________________________________________________ (5)