The Innate and Adaptive Immune
System and The Lymphatic
System
Anatomy and Physiology
Review
Instructions – Race To The Board
• The class will be divided into six separate
teams.
• One representative from each team will come
up to the whiteboard to answer a question (in
the PowerPoint) within a one minute time
frame.
• The first person to write the correct answer
on the board wins a point for his/her team.
Instructions Continued
• The Catch: The students at the board only get
ONE try to write the correct answer.
• If all students at the board answer the
question incorrectly, the first person from the
audience (on any of the teams) who raises
their hand and answers the question correctly,
earns a point for their team.
QUESTIONS!?
Let’s Begin!
Question 1
• __________ cells enable the Immune System
to respond more quickly if the same antigen is
encountered a second time.
Question 1 Answer
• Memory Cells
Question 2
• Immunity is the ability to resist infection and
disease through the activation of __________.
• Clue: What type of defenses?
Question 2 Answer
• Adaptive or Specific Defenses
Question 3
• _________ _________ prevent bacteria from
breaching the small intestinal wall.
Question 3 Answer
• Peyer’s Patches
Question 4
• Suppressor T cells (aka T regs) act to depress
responses of other ________ and _________.
Question 4 Answer
• T cells and B cells
Question 5
• The cells that are vital to the body’s ability to
resist or overcome infection and disease are
called ______________.
Question 5 Answer
• Lymphocytes
Question 6
• The structures in the Lymphatic System that
filter lymph before it reaches the veins are the
_______ ________.
Question 6 Answer
• Lymph Nodes
Question 7
• The type(s) of lymphocytes that differentiate
into plasma cells, which secrete antibodies,
are called _________.
Question 7 Answer
• B cells
Question 8
• The three classes of lymphocytes found in the
blood are ________, ________, and NK cells.
Question 8 Answer
• B cells and T cells
Question 9
• The body’s nonspecific (innate) defenses
include: _________, _________, _________,
and _________.
Question 9 Answer
• Skin, Complement, Inflammation, and
Interferon
Question 10
• The first line of cellular defense against a
pathogen is _____________.
Question 10 Answer
• Phagocytes
Question 11
• Destruction of target cells by the local release
of cytokines, lymphotoxins, or perforin
involves ____________.
• CLUE: What type of cells?
Question 11 Answer
• Cytotoxic T Cells
Question 12
• The reason the primary response takes time
to develop is that _____________.
Question 12 Answer
• Antigen-activated B cells must differentiate
into plasma cells.
Question 13
• The specificity of an antibody can result in
___________.
Question 13 Answer
• Variable segments of light and heavy chains
Question 14
• When an immune response mistakenly
targets normal body cells and tissues, the
result is ______________.
Question 14 Answer
• An autoimmune disorder
Question 15
• The three main functions of the Lymphatic
System are: ___________, ____________,
and ____________.
Question 15 Answer
• Fluid Balance (Blood and Lymph), Fat
Absorption, Immunological Defense (fights
infection).
Question 16
• Lymphocytes that assist in the regulation and
coordination of the immune response are
____________ and ____________.
• CLUE: Specific T cell types
Question 16 Answer
• Helper T cells and Supressor T cells
Question 17
• Lymphocytes that travel from the bone
marrow to the thymus to mature are called
____________.
Question 17 Answer
• T cells
Question 18
• At the site of infection (cut or wound),
____________ die and form pus from the
innate immune response.
Question 18 Answer
• Neutrophils
Question 19
• Hemocytoblasts in the bone marrow produce
lymphoid stem cells that generate _________,
___________, and ___________.
• CLUE: Name three major cell groups.
Question 19 Answer
• B cells, NK cells, and T cells
Question 20
• Normal lymphocyte populations are
maintained through lymphopoiesis in the
____________ and __________.
• CLUE: Name two locations within the body of
lymphocyte production and maturation.
Question 20 Answer
• Red bone marrow and Thymus
Question 21
• The protein(s) that interfere(s) with the
replication of viruses is (are) ___________.
Question 21 Answer
• Interferons
Question 22
• Antigen-presenting cells (APCs) display
antigen fragments on ____________.
• CLUE: What complex?
Question 22 Answer
• Class II MHC (Major Histocompatibilty
Complex) proteins
Question 23
• A specific defense mechanism is always
activated by _________.
Question 23 Answer
• An antigen
Question 24
• When the Lymphatic System is prevented
from doing its job and fluid builds up in the
tissues, ___________ is the medical term to
describe this condition.
Question 24 Answer
• Edema
Question 25
• The role of accessory cells in immunity is to
___________________________________.
Question 25 Answer
• Digest foreign cells and molecules and present
antigens.
Question 26
• Anatomically, lymph vessels resemble
_________.
• CLUE: What type of vessels from the
Cardiovascular System?
Question 26 Answer
• Veins
Question 27
• Infection with the HIV virus occurs through
__________________.
Question 27 Answer
• Contact with an infected person’s bodily fluids
(blood, semen, breast milk, etc.)
Question 28
• The thymus gland is positioned ___________.
Question 28 Answer
• Just behind the sternum.
Question 29
• The three functions of the spleen are to
______, _______, and _______.
Question 29 Answer
• Removed aged red blood cells (RBCs), house
lymphocytes, and store some blood
components (serves as blood reservoir)
Question 30
• Protection of superficial lymph nodes and the
lymphatic vessels in the abdominopelvic cavity
is provided by the ___________ system.
• CLUE: Which body system aids in the
“pumping” of lymph throughout the body?
Question 30 Answer
• Muscular System (Smooth muscles and
skeletal muscles)