Test Higher Lower Albumin Conventional Units 3.5-5.0 g/dL Dehydration Chronic liver disease, malabsorption, malnutrition, nephrotic syndrome Ammonia Amylase 15-45 mcg N/dL 30-122 U/L Severe liver disease Acute and chronic pancreatitis, mumps (salivary gland disease), perforated ulcers Heart failure b-Type natriuretic peptide (BNP) Bilirubin (Total) <100 pg/mL 0.2-1.2 mg/dL Biliary obstruction, impaired liver function, hemolytic anemia, pernicious anemia Acute osteoporosis, hyperparathyroidism, vitamin D intoxication, multiple myeloma Calcium (total) 8.6-10.2 mg/dL Chloride 96-106 mEq/L Metabolic acidosis, respiratory alkalosis, corticosteroid therapy, uremia <200 mg/dL Biliary obstruction, hypothyroidism, idiopathic hypercholesterolemia, renal disease, uncontrolled diabetes Cholesterol High-density lipoproteins (HDLs) Low-density lipoproteins (LDLs) Cortisol Creatine Creatinine Creatine kinase (CK) Acute alcoholism, cirrhosis of liver, extensive destruction of pancreas Acute pancreatitis, hypoparathyroidism, liver disease, malabsorption syndrome, renal failure, vitamin D deficiency Addison’s disease, diarrhea, metabolic alkalosis, respiratory acidosis, vomiting Extensive liver disease, hyperthyroidism, malnutrition, corticosteroid therapy Male: >40 mg/dL Female: >50 mg/dL Recommended: <100 mg/dL Near optimal: 100-129 mg/dL Moderate risk for CAD: 130-159 mg/dL High risk for CAD: >160 mg/dL 8 AM: 5-23 mcg/dL Cushing syndrome, Pancreatitis 8 PM: <10 mcg/dL 0.2-1.0 mg/dL Active rheumatoid arthritis, biliary obstruction, hyperthyroidism, renal disorders, severe muscle disease 0.6-1.3 mg/dL Severe renal disease Male: 20-200 U/L Musculoskeletal injury or Female: 20-180 disease, myocardial infarction, U/L severe myocarditis, exercise, numerous IM injections Adrenal insufficiency, panhypopituitary states Acute myocardial infarction Folate (folic acid) <4%-6% of total CK 5-16 ng/mL Glucose (fasting) 70-99 mg/dL Acute stress, Cushing disease, diabetes mellitus, hyperthyroidism, pancreatic insufficiency Insulin (fasting) 4-24 μU/mL CK-MB Hypothyroidism Iron, total 50-175 mcg/dL Acromegaly, adenoma of pancreatic islet cells, untreated mild case of type 2 diabetes Excessive RBC destruction Lactic acid (LLactate) Lipase 6.3-22.5 mcg/dL Acidosis, heart failure, shock 31-186 U/L Acute pancreatitis, hepatic disorders, perforated peptic ulcer Addison’s disease, hypothyroidism, renal failure Healing fractures, hypoparathyroidism, renal disease, vitamin D intoxication Addison’s disease, diabetic ketosis, massive tissue destruction, renal failure Magnesium 1.5-2.5 mEq/L Phosphorus (phosphate) 2.4-4.4 mg/dL Potassium 3.5-5.0 mEq/L Sodium 135-145 mEq/L Prostate-specific antigen (PSA) Proteins Total <4 ng/mL Protein Globulin Albumin/globulin ratio 2.0-3.5 g/dL 1.5:1-2.5 : 1 Testosterone T4 (thyroxine), total 6.4-8.3 g/dL Male: 280-1100 ng/dL Female: 15-70 ng/dL 4.6-11.0 mcg/dL Dehydration, impaired renal function, primary aldosteronism, corticosteroid therapy Prostate cancer Alcoholism, hemolytic anemia, inadequate diet, malabsorption syndrome, megaloblastic anemia Addison’s disease, hepatic disease, hypothyroidism, insulin overdosage, pancreatic tumor, pituitary hypofunction Inadequately treated type 1 diabetes mellitus Iron-deficiency anemia, anemia of chronic disease Chronic alcoholism, severe malabsorption Diabetes mellitus, hyperparathyroidism, vitamin D deficiency Cushing syndrome, diarrhea (severe), diuretic therapy, gastrointestinal fistula, pyloric obstruction, starvation, vomiting Dehydration, impaired renal function, primary aldosteronism, corticosteroid therapy Burns, cirrhosis (globulin fraction), dehydration Liver disease, malabsorption Multiple myeloma (globulin fraction), shock, vomiting Malnutrition, nephrotic syndrome, proteinuria, renal disease, severe burns Hypofunction of testes, hypogonadism Polycystic ovary, virilizing tumors Hyperthyroidism, thyroiditis Cretinism, hypothyroidism, myxedema Ages 20-50: 70-204 T3 (triiodothyronine), ng/dL Ages >50: 40-181 total ng/dL 0.4-4.2 μU/mL Thyroidstimulating hormone (TSH) Transaminases 10-30 U/L • Aspartate aminotransferase 10-40 U/L (AST) • Alanine aminotransferase (ALT) <150 mg/dL Triglycerides Troponins (cardiac) • Troponin T (cTnT) • Troponin I (cTnI) Urea nitrogen (BUN) Uric acid Activated partial thromboplastin time (aPTT) Prothrombin time (Protime, PT) D-Dimer <0.5 ng/mL (<0.5 mcg/L) <0.1 ng/mL (<0.1 mcg/L) 6-20 mg/dL Male: 4.4-7.6 mg/dL Female: 2.3-6.6 mg/dL 25-35 se 11-16 sec <250 ng/mL Male: 4.3-5.7 × 106/Μl Female: 3.8-5.1 × 106/μL <30 mm/hr (some Erythrocyte sedimentation rate gender variation) (ESR) Erythrocyte count (altitude dependent) Hemoglobin† (altitude dependent) Male: 13.2-17.3 g/dL Hyperthyroidism Hypothyroidism Myxedema, primary hypothyroidism, Graves’ disease Liver disease, myocardial infarction, pulmonary infarction, acute hepatitis Secondary hypothyroidism Liver disease, shock Diabetes mellitus, hyperlipidemia, hypothyroidism, liver disease Myocardial infarction Malnutrition Increase in protein catabolism (fever, stress), renal disease, urinary tract infection Gout, gross tissue destruction, highprotein weight reduction diet, leukemia, renal failure Malnutrition, severe liver damage HEMATOLOGY Deficiency factors I, II, V, VIII, IX, X, XI, XII; hemophilia, liver disease; heparin therapy Warfarin therapy; deficiency of factors I, II, V, VII, and X; vitamin K deficiency; liver disease DIC, myocardial infarction, deep vein thrombosis, unstable angina Dehydration, high altitudes, polycythemia vera Moderate increase: acute hepatitis, myocardial infarction; rheumatoid Arthritis Marked increase: acute and severe bacterial infections, malignancies, pelvic inflammatory disease COPD, high altitudes, polycythemia Administration of uricosuric drugs Anemia, leukemia, posthemorrhage Malaria, severe liver disease, sickle cell anemia Anemia, hemorrhage Female: 11.7-15.5 g/dL Male: 39%-50% Female: 35%-47% Hematocrit† (altitude dependent) 4.0%-6.0% Hemoglobin, glycosylated (A1C) 150-400 × 103/μL Platelets (thrombocytes) White blood cell count 4.0-11.0 × 103/μL Antinuclear antibody (ANA) Negative at 1:40 dilution Anti-DNA antibody C-reactive protein (CRP) <70 IU/mL 6.8-820 mcg/dL Rheumatoid factor Negative or titer <1:17 (RF) Specific gravity Urine pH Urine Pressure Glucose Protein • Lumbar • Cisternal • Ventricular Chloride Arterial pH Venous pH PaCO2 PaO2 Dehydration, high altitudes, polycythemia Anemia, hemorrhage, overhydration Poorly controlled diabetes mellitus Sickle cell anemia, chronic renal failure, pregnancy Acute leukemia, DIC, Thrombocytopenic purpura Acute infections, chronic granulocytic leukemia, chronic pancreatitis, cirrhosis, collagen disorders, polycythemia, postsplenectomy Inflammatory and infectious processes, leukemia Chronic hepatitis, rheumatoid arthritis, scleroderma, systemic lupus erythematosus SEROLOGY/IMMUNOLOGY Systemic lupus erythematosus Acute infections, any inflammatory condition, widespread malignancy Rheumatoid arthritis, Sjögren’s syndrome, systemic lupus erythematosus 1.003-1.030 Albuminuria, dehydration, glycosuria 4.0-8.0 Urinary tract infection, urine allowed to stand at room temperature CEREBROSPINAL FLUID ANALYSIS 60-150 mm H2O Hemorrhage, intracranial tumor, meningitis 40-70 mg/dL Diabetes mellitus, viral infections of CNS 15-45 mg/dL • GBS, poliomyelitis, trauma 15-25 mg/dL • Syphilis of CNS 5-15 mg/dL • Acute meningitis, brain tumor, chronic CNS infections, multiple sclerosis 118-132 mEq/L Uremia 7.35-7.45 7.32-7.43 35-45 80-100 mm Hg Aplastic anemia, side effects of chemotherapy and irradiation BLOOD GASES Alkalosis Compensated metabolic alkalosis Administration of high concentration of oxygen Diabetes insipidus Respiratory or metabolic acidosis Head injury, spinal tumor, subdural hematoma Bacterial infections and tuberculosis of CNS Bacterial infections of CNS (meningitis, encephalitis) Acidosis Compensated metabolic acidosis Chronic lung disease, decreased cardiac output PvCO2 PvO2 38-55 mm Hg 38-42 mm Hg Respiratory acidosis Administration of high concentration of oxygen Respiratory alkalosis Chronic lung disease, decreased cardiac output