organ farming

advertisement
Organ Farming application in recent society
Mark Lyu



In recent days, scientists have
cultivated a range of human body
structures, these small-scale human
organs are known as “organoids”.
Organoids are used to study human
organ function and structure and also
test potential drugs.
Lab-grown organs have less
controversy than donated organs in
organ transplantations because these
organs don’t have ethical issues related
to human rights or animal protection.


One of the most remarkable
advances in regenerative
medicine has been the
development of "miniorgans"— tiny versions of,
say, a patient's lungs or
intestines—that are grown in
a lab using stem cells.
These "organoids" can be
used to see how an individual
person will respond to
different drugs, even before
they're treated. Eventually,
they could be transplanted to
help repair tissue.
(Artificial organs is related to this
technology. Along with the development
and discovery in organoids using,
artificial organs will develop on accuracy
and functional similarities compare to
human organs.)


An organoid is a miniaturized and
simplified version of an organ produced in
vitro in three dimensions that shows
realistic micro-anatomy.
They are derived from one or a
few cells from a tissue, embryonic stem
cells or induced pluripotent stem cells,
which can self-organize in threedimensional culture owing to their selfrenewal and differentiation capacities.


According to the search results for organoids
law and organ transplantation, laws on
organoids and lab-grown organs are not
separated from the transplantation related
laws.
It means Canadian government has not yet
developed a systematic limitation on
organoids using.

Organoids are mostly used in medicine
development, no significant application in
industry and agriculture yet.




Using organoids, scientists are able to test potential medicine
which provides more possible treatments that fits the
patient’s situation.
Systematic organoid produce will reduce the cost of
developing drugs.
Flexibility: There are limitless applications of this technique.
Any drug, for any disease, affecting any organ could
theoretically be shrunk down and subjected to a battery of
tests in a Petri dish before being pumped into a sick person.
The use of these organoids has thus greatly contributed to
expanding our understanding of the processes
of organogenesis, and the field of developmental biology.

No significant risks is shown in study of organiods, for
transplantation the lab-grown organ may show unexpected
mutations but it can be detected before transplanting to the
patient.

Disadvantages of organiods are:

Time consuming and expensive

Improvements come slowly

Testing and analyzing potential medicines is a long,
tedious, and labor-intensive process



Oragnoid is related to Molecular Genetics by
DNA structures and mutations.
To achieve the goal of developing
personalized organoid, the DNA must be
collected from the patient and organoid will
be produced based on patients DNA.
Mutations on human organs can be studied
by using organoid to simulate the organ
mutations in different environments.





Legislative Services Branch. (2018, December 03). Consolidated federal laws
of canada, Safety of Human Cells, Tissues and Organs for Transplantation
Regulations. https://laws-lois.justice.gc.ca/eng/regulations/sor-2007118/20150211/P1TT3xt3.html
Organoid. (2018, November 28). https://en.wikipedia.org/wiki/Organoid
Freethink. (n.d.) Robots Are Mass Producing Mini-Organs.
https://www.freethink.com/articles/robots-are-mass-producing-miniorgans
Cassandra Willyard. (2015, July 29). The boom in mini stomachs, brains,
breasts, kidneys and more. https://www.nature.com/news/the-boom-inmini-stomachs-brains-breasts-kidneys-and-more-1.18064
Weisberger, M. (2017, July 03). 11 Body Parts Grown in the Lab.
https://www.livescience.com/59675-body-parts-grown-in-lab.html
Download
Related flashcards

Molecular biology

64 cards

Peptide hormones

66 cards

Molecular biology

92 cards

Create Flashcards