FINAL PROGRAM
Tissue Engineering and Regenerative
Medicine International Society
www.termis.org/am2014
WELCOME MESSAGE
Dear Colleagues,
On behalf of the Scientific Advisory Committee, it is our great pleasure to welcome you to Washington, D.C. and the
2014 Tissue Engineering and Regenerative Medicine International Society – Americas Chapter Annual Conference
(TERMIS-AM 2014).
The theme for the 2014 TERMIS-AM Meeting is “Restoring Lives Through Regenerative Medicine,” reflecting the
increasing need to consider the societal impact of tissue engineering. To this end, the 2014 scientific program will
focus on the impact of regenerative medicine upon patient lives. We also plan a close cooperation with federal
institutions, including the National Institutes of Health (NIH), National Science Foundation (NSF), Food and Drug
Administration (FDA), and National Institute of Standards and Technology (NIST) to provide the TERMIS-AM meeting
with scientific content that has not been achieved in earlier meetings as well as a strong patient-oriented point of view.
The scientific program is composed of 3 keynote presentations, 5 award presentations, 4 pre-conference workshops,
and 40 concurrent sessions. In addition, the Student and Young Investigator Section has organized a number of
events, including a mentoring lunch, career panel, and visit to the FDA’s White Oak campus. With over 600 abstract
submissions, we expect that the meeting will illustrate the latest scientific developments in tissue engineering and
regenerative medicine.
Washington, D.C., is the capital of the United States of America, one of the most popular tourist cities in the country,
and home to many of the leading institutions, societies, museums and attractions in the nation. Of particular interest
to TERMIS-AM, Washington, D.C., is the home to federal institutions that play a key role in tissue engineering and
regenerative medicine, including NIH, NSF, FDA, and NIST. In addition, Washington, D.C., is home to many cultural
attractions (Kennedy Center, Ford’s Theatre, Smithsonian Institution’s 19 museums and galleries, National Zoo, US
Holocaust Memorial Museum, and at least 50 other museums), national landmarks (National Mall, Lincoln Memorial,
Washington Monument, Capitol Building, White House), and shopping (Georgetown and DuPont Circle).
We encourage you to actively participate in the meeting’s many activities that are designed to facilitate networking
opportunities and foster new collaborations.
Once again, welcome to TERMIS-AM 2014!
Best regards,
John Fisher, PhD, University of Maryland, Conference Chair
Jennifer Elisseeff, PhD, Johns Hopkins University, Conference Program Chair
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TERMIS–AM • 2014
CONTENTS
Scientific Advisory Committee.................. 4
Conference Information................................ 5
Program at a Glance....................................... 6
Hotel Floor Plans.............................................. 8
Scientific Information..................................... 9
SYIS-AM Activities........................................... 10
WFIRM Award Winners.................................. 11
TERMIS-AM 2014 Award Recipients.......... 12
Keynote Symposia........................................... 14
Pre-Conference Workshops......................... 14
Sunday Concurrent Sessions....................... 17
Monday Concurrent Sessions...................... 20
Tuesday Concurrent Sessions..................... 23
Sponsors.............................................................. 25
Exhibitor Floor Plan........................................ 26
Exhibitors............................................................. 27
Poster Abstracts............................................... 29
SCIENTIFIC ADVISORY
ORGANIZING COMMITTEE
CONFERENCE CHAIR
John Fisher, PhD, Unversity of Maryland
CONFERENCE PROGRAM CHAIR
Jennifer Elisseeff, PhD, Johns Hopkins University
Hai-Quan Mao,
Johns Hopkins University
Kristi Anseth,
University of Colorado
Kacey Marra,
University of Pittsburgh
Anthony Atala,
Wake Forest University
Antonios Mikos,
Rice University
Satyavrata Samavedi – SYIS-AM
Secretary
Stephen Badylak,
University of Pittsburgh
Laura Niklason,
Yale University
Johhny Lam – SYIS-AM Treasurer
Eric Brey,
Illinois Institute of Technology
Steven Pollack,
Food and Drug Administration
Jason Burdick,
University of Pennsylvania
Milica Radisic,
University of Toronto
George Christ,
Wake Forest University
Mahendra Rao,
National Institutes of Health
Curt Civin,
University of Maryland
Chris Gemmiti,
Ridgewood Consulting LLC
Heinz Redl,
Ludwig Boltzmann Institute
for Experimental and Clinical
Traumatology
Warren Grayson,
Johns Hopkins University
Shelly Sakiyama-Elbert,
Washington University in St. Louis
Jordan Green,
Johns Hopkins University
Carl Simon,
National Institutes of Health
Robert Guldberg,
Georgia Institute of Technology
Johnna Temenoff,
Georgia Institute of Technology
Steven Jay,
University of Maryland
Mark Van Dyke,
Virginia Tech
David Kaplan,
Tufts University
William Wagner,
University of Pittsburgh
Eva Lai,
Johns Hopkins University
Jason A. Wertheim,
Northwestern University and Jesse
Brown VA Medical Center
Jennie Leach,
University of Maryland Baltimore
County
4
SYIS-AM Organizing
Committee
Eben Alsberg,
Case Western Reserve University
Celia Witten,
Food and Drug Administration
Wei Liu,
Shanghai Jiao Tong University
James Yoo,
Wake Forest University
Catherine Kuo,
Tufts University
Kaiming Ye,
SUNY Binghamton
Peter Ma,
University of Michigan
Grace Zhang,
George Washington University
TERMIS–AM • 2014
Tracy Hookway – SYIS-AM Chair
Sean Murphy – SYIS-AM Chair
of the Scientific & Professional
Development Committee
Kimberly Ferlin – SYIS-AM Chair
of the Meetings Committee & the
Communications Officer
Kellin Krick – SYIS-AM Meetings
Committee
FINAL PROGRAM
Official/Social Events
WELCOME RECEPTION
CONFERENCE INFORMATION
Registration
REGISTRATION DESK
Location: Ballroom Level Lobby
Date & Time:
•D
ecember 13 (Sat), 7:30 am – 8:00 pm
•D
ecember 14 (Sun), 7:00 am – 6:00 pm
•D
ecember 15 (Mon), 7:00 am – 6:00 pm
•D
ecember 16 (Tue), 7:00 am – 4:00 pm
CERTIFICATE OF ATTENDANCE
Certificate of attendance will be provided to all registered attendees.
You can receive your certificate at the registration desk on Tuesday
December 16, from 7:00 am – 4:00 pm.
WI-FI ACCESS
Wi-Fi will be offered in the Speaker Ready Room, the conference
meeting space, and the registration area.
Online Publication of Abstracts
To access the online publication of abstracts please visit:
http://online.liebertpub.com/toc/tea/20/S1
Exhibition
Location: Renaissance West & East
Date & Time:
December 13 (Sat),
6:00 pm – 8:00 pm – Welcome Reception
December 14 (Sun),9:30 am – 10:00 am – Coffee Break in Exhibit Hall
2:30 pm – 3:00 pm – Coffee Break in Exhibit Hall
4:30 pm – 6:30 pm – E
xhibit Viewing/Reception
– Poster Session I
December 15 (Mon),9:30 am – 10:00 am – Coffee Break in Exhibit Hall
2:30 pm – 3:00 pm – Coffee Break in Exhibit Hall
4:30 pm – 6:30 pm – E
xhibit Viewing/Reception
– Poster Session II
December 16 (Tue),9:30 am – 10:00 am – Coffee Break in Exhibit Hall
2:30 pm – 3:00 pm – Coffee Break in Exhibit Hall
POSTER SESSION I – DECEMBER 14 (SUN), 4:30 pm – 6:30 pm
Exhibit Hall - Renaissance West and East
Business Plan Competition Honorable Mention Posters
Magni (Montgomery et al)
Scifoger (Zellander)
Nanochon (Holmes and Castro)
Perago (no names given)
Ligamend (Farraro and Woo)
TELO-Tox (Vyas and Moran)
Location: Renaissance West & East
Date & Time: December 13 (Sat),
6:00 pm – 8:00 pm
CLOSING CEREMONY
Location: Grand Ballroom – Central and
South Salon
Date & Time: December 16 (Tue) –
Closing Ceremony
TERMIS-AM COUNCIL
MEETING & LUNCH
Location: Mount Vernon Square A & B
Date & Time: December 14 (Sun),
11:30 am – 2:45 pm
CONFERENCE GALA
Location: National Portrait Gallery,
The Robert and Arlene Kogod Courtyard
Date & Time: December 15 (Mon),
7:30 pm – 9:30 pm
Address: 8th and F Sts. NW. Washington,
D.C. 20001
Attendees of the 2014 TERMIS-AM conference
will enjoy an evening at the National Portrait
Gallery. The event will provide food and
beverages at The Robert and Arlene Kogod
Courtyard and you will have the option to
view the First & Second Floor Galleries at the
National Portrait Gallery. No food or beverage is
allowed in the First & Second Floor Galleries.
Tickets for accompanying persons can be
purchased at the registration desk for $100.00 USD.
The National Portrait Gallery is a 5 minute walk
(5 blocks) from the Renaissance Washington,
DC Downtown Hotel. Taxis will also be available
outside of the hotel.
National Portrait Gallery Website:
http://www.npg.si.edu
POSTER SESSION II – DECEMBER 15 (MON), 4:30 pm – 6:30 pm
Exhibit Hall – Renaissance West and East
SYIS-AM Undergraduate Poster Session
www.termis.org/am2014
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PROGRAM AT A GLANCE
DECEMBER 13 (SATURDAY)
Workshop #1
The Alliance for Regenerative Medicine’s Workshop on Commercialization Strategies for Tissue Engineered Products
Grand Ballroom: Central Salon
8:00 am - 12:00 pm
Workshop #2
Restoring Lives and Functions for the Wounded Warriors Workshop
Grand Ballroom: South Salon
Workshop #3
Government Efforts on the Path to Patients for Regenerative Medicine Therapies: A MATES Symposium
Congressional A
Workshop #4
Women’s Luncheon
“Avoiding traps”
Women in Tissue Engineering and Regenerative Medicine Luncheon
Mount Vernon Square A and B
12:00 pm - 4:00 pm
Opening Symposium Sponsored by ASTS
History and Future of Transplant and Tissue Engineering
W.P. Andrew Lee (30 mins) and Joseph P. Vacanti (30 mins)
Keynote -History and Future of Transplant and Tissue Engineering
Panel Discussion lead by Jason Wertheim
(30 minutes panel and Q&A)
Grand Ballroom: Central and South Salon
4:00 pm - 5:30 pm
Welcome Reception
Renaissance West and East
6:00 pm -8:00 pm
DECEMBER 14 (SUNDAY)
8:00 am - 9:30 am
Keynote Symposium I
Welcome Announcement (5 minutes)
Keynote I: Biomaterials for Tissue Engineering - Antonios Mikos, PhD, Rice University
Lifetime Achievement Award – Regenerative Medicine: Current Concepts and Changing Trends Anthony Atala, MD, Wake Forest Institute for Regenerative Medicine
Grand Ballroom: Central and South Salon
9:30 am - 10:00 am
Coffee Break
Exhibit Hall - Renaissance West and East
Concurrent Session I
10:00 am - 11:30 am
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Perspectives on Tissue Engineering &
Regenerative Medicine Education
Decellularized Tissues
Stem and Progenitor Cell-Based Approaches
to Musculoskeletal Tissue Therapies
AM-IC One Day Event
Cardiac Tissue Engineering: Current State
and Perspectives
11:30 am - 1:00 pm
Student Career Panel
Meeting Room 15
11:30 am - 2:45 pm
TERMIS-AM Council Meeting & Lunch
Mount Vernon Square A & B
Concurrent Session II
1:00 pm - 2:30 pm
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Composite Tissue-Organ Transplantation and
Tissue Engineering
Naturally-Derived/Inspired Biomaterials
Neurogenic Differentiation and Tissue
Engineering Strategies
AM-IC One Day Event
Microvascular Tissue Engineering
Coffee Break
Exhibit Hall - Renaissance West and East
2:30 pm - 3:00 pm
Concurrent Session III
3:00 pm - 4:30 pm
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Tissue-Organ Replacement and Preclinical
Models
Gradients, Patterning and Processing of
Biomaterials
Engineering Tissues for In Vitro Screening
and Diagnostics Imaging I
AM-IC One Day Event
Immunology/Immunoengineering in Tissue
Engineering
4:30 pm - 6:30 pm
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TERMIS–AM • 2014
Exhibit Viewing/Reception - Poster Session I
Renaissance West & East
PROGRAM AT A GLANCE
DECEMBER 15 (MONDAY)
8:00 am - 9:30 am
Keynote Symposium II
Welcome Announcement (5 minutes)
Keynote II: Oxygen Supply and Demand in Regenerative Medicine – Gregg Semenza, MD, PhD, Johns Hopkins University
Senior Scientist Award – Designer Hydrogels In0fluence Cell Fate – Molly Shoichet, PhD, University of Toronto
Young Investigator Award – Recycling: Turning Fat into Vascularized Bone and Skeletal Muscle – Warren Grayson, PhD, Johns Hopkins University
Grand Ballroom: Central and South Salon
9:30 am - 10:00 am
Coffee Break
Exhibit Hall - Renaissance West and East
Concurrent Session IV
10:00 am - 11:30 am
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Business Plan Competition
Micro/Nano Biomaterials and Scaffold
Building Blocks
Cardiac and Smooth Muscle Cell
Differentiation and Function
Drug Delivery
Advances in Cardiovascular Tissue
Engineering Methods
Break
11:30 am - 1:00 pm
Concurrent Session V
1:00 pm - 2:30 pm
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Biofabrication and Bioreactors
Implants and Host Response to Biomaterials
Stem Cell Function, Migration and Trafficking
Why Standards are Critical for Getting TEMPs
to Market
Dental and Craniofacial Regeneration I
Coffee Break
Exhibit Hall - Renaissance West and East
2:30 pm - 3:00 pm
Concurrent Session VI
3:00 pm - 4:30 pm
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Strategies for Innervation, Nerve Repair and
Integration
Engineered Biomaterials to Regulate Cell
Fate and Function I
Engineering Tissues for In Vitro Screening
and Diagnostics Imaging II
Skin, Wound Healing and Inflammation
Dental and Craniofacial Regeneration II
4:30 pm - 6:30 pm
Exhibit Viewing/Reception - Poster Session II
Renaissance West & East
7:30 pm - 9:30 pm
Conference GALA
OFFSITE - National Portrait Gallery
8th and F Sts NW, Washington, DC 20001
DECEMBER 16 (TUESDAY)
8:00 am - 9:30 am
Keynote Symposium III
Welcome Announcement (5 minutes)
Keynote Session III - Immunoengineering for Biomedical Applications – Darrell Irvine, PhD, Massachusetts Institute of Technology
Mary Ann Liebert, Inc. Outstanding Student Award - PPF Reinforced Pericardium as a Hybrid Material for Cardiovascular Applications –
Laura Bracaglia – University of Maryland
Educational Award - Educational Initiatives within the McGowan Institute for Regenerative Medicine – Bryan Brown, PhD, University of Pittsburgh
The Losing Case for Innovation: Why Congress Doesn’t Fund Research – Milan Yager, AIMBE
Grand Ballroom: Central and South Salon
9:30 am - 10:00 am
Coffee Break
Exhibit Hall - Renaissance West and East
Concurrent Session VII
10:00 am - 11:30 am
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Strategies for Innervation, Nerve Repair and
Integration
Engineered Biomaterials to Regulate Cell
Fate and Function I
Engineering Tissues for In Vitro Screening
and Diagnostics Imaging II
Skin, Wound Healing and Inflammation
Dental and Craniofacial Regeneration II
Student Meet Mentor Lunch
Mount Vernon Square A & B
11:30 am - 1:00 pm
Concurrent Session VIII
1:00 pm - 2:30 pm
Grand Ballroom: South Salon
Grand Ballroom: Central Salon
Grand Ballroom: North Salon
Congressional Hall A
Congressional Hall B
Imaging and Assessment
Tumor Development and Cancer
Tissue Engineering and Regenerative
Medicine Strategies
Musculoskeletal Tissue Regeneration
Strategies for Respiratory, Urologic and
Gastrointestinal Tissue Engineering
2:30 pm - 3:00 pm
Coffee Break
Exhibit Hall - Renaissance West and East
3:00 pm - 4:30 pm
Closing Ceremony
2 Wake Forest Institute for Regenative Medicine Young Investigator Awards
SYIS Poster Awards Presentations
TERMIS-AM Business Meeting
Grand Ballroom: Central and South Salon
www.termis.org/am2014
7
BALLROOM LEVEL
TERMIS–AM
EXHIBIT HALL
MEETING ROOM LEVEL
8
TERMIS–AM • 2014
FINAL PROGRAM
SCIENTIFIC INFORMATION
Instruction for Presenters
ORAL PRESENTATIONS
Each presenter has 15 minutes for his/her presentation (12 minutes for presentation and 3 minutes for discussion and
questions). The keynote speaker has 30 minutes for his/her presentation (25 minutes for presentation and 5 minutes
for discussion and questions). All presentation files should be submitted 2 hours prior to the session.
Presenters will be able to upload their presentations in the speaker ready room in Meeting Room 16.
POSTER PRESENTATIONS
Posters for Poster Session I and Poster Session II will be displayed in the Renaissance Ballroom. Each poster board is
identified with a corresponding number to the list in the program book. The designated poster sessions are scheduled
during the following times:
Poster Session I – Sunday, December 14 from 4:30 pm – 6:30 pm
Poster Session II – Monday, December 15 from 4:30 pm – 6:30 pm
The actual size of a poster board is 94” wide by 48” tall. There will be two posters per side. The recommended poster
size is in the 45” wide by 45” tall. The poster board is self-standing. Thumbtacks will be provided in the Exhibit Hall,
Renaissance West and East.
The presenting author is expected to stand beside his/her poster for detailed discussion during the designated
presenting time. Posters must be taken down after the session is over. Any remaining posters will be collected by the
staff and kept at the registration desk. The registration desk will not be held responsible for any loss or damage of the
materials.
SYIS-AM Poster Awards
The top three (3) selected students and young investigators from the SYIS-AM poster session (Poster Session I and
Poster Session II) will be awarded certificates and prizes at the Closing Ceremony on Tuesday, December 16 from
3:00 pm – 4:30 pm.
SYIS-AM POSTER JUDGING INSTRUCTIONS
Please pick up your poster judging materials at the Registration Desk on Sunday, December 14. The SYIS-AM posters
will be in the front foyer outside of the Exhibit Hall. They will be able to keep their posters up through Poster Session I
and Poster Session II.
UNDERGRADUATE POSTER SESSION
The undergraduate poster session will be conducted during Poster Session II, on December 15 from 4:30 pm – 6:30 pm
outside the Exhibit Hall (Renaissance West & East) in the right hallway.
www.termis.org/am2014
9
SYIS-AM ACTIVITIES
OPENING RECEPTION & SYIS BUSINESS MEETING
Saturday, December 13
6:00 pm – 8:00 pm
Renaissance West and East Exhibit Hall
TERMIS-AM SYIS is pleased to host the Opening
Reception on the evening of Saturday, December 13th to
celebrate the opening of the 2014 TERMIS-AM Meeting
in DC. The SYIS reception is open to all students and
young investigators and will be a fun evening to kick-off
the TERMIS-AM meeting. This event is an opportunity to
catch up with friends and meet other young scientists
while enjoying food and drinks. We will also hold our
annual business meeting and discuss the purpose and
goals of the SYIS-AM for the 2014 conference, as well
provide information on the upcoming SYIS events.
CAREER PANEL DISCUSSION
Sunday, December 14
11:30 am - 1:00 pm
Meeting Room 15
TERMIS-AM SYIS is pleased to host the Career
Opportunities Discussion Panel on Sunday, December 14th
at lunch during the TERMIS-AM Washington, D.C. Meeting.
This discussion panel will consist of young professionals
representing careers in academia, industry, government
agencies and institutes, and entrepreneurial activities.
This is a great opportunity for students and young
investigators to hear the recent experiences of
these scientists in choosing their career paths, the
opportunities and challenges of their chosen career, and
providing advice on how you can achieve your career
goals. This interactive panel is designed to facilitate open
discussion, and to allow students and young investigators
to have their questions answered by the panel and other
attendees. At previous meetings, this event has been
very beneficial for students and young investigators
thinking about pursuing a career in any of these fields.
Please use the sign-up sheet below to register for this
event. We look forward to seeing you in Washington D.C!
FDA CAMPUS & LAB TOUR
Monday, December 15
12:00 pm – 4:00 pm
FDA campus – Silver Spring, MD
TERMIS-AM SYIS is pleased to host Tours of the FDA
Campus on Monday, December 15th during the TERMIS-AM
Meeting in Washington, DC. This year, SYIS-AM will be
offering a unique opportunity to visit the FDA campus in
10
TERMIS–AM • 2014
Silver Spring, MD, to hear about what type of research is
being conducted at the agency as well as to tour some of
the newest research laboratories. Transportation will be
provided from the conference center to the campus.
SYIS-AM POSTER AWARDS
(During the Closing Ceremony)
Tuesday, December 16, 3:00 pm – 4:30 pm
Grand Ballroom: Central and South Salon
UNDERGRADUATE POSTER SESSION
Monday, December 15, 4:30 pm – 6:30 pm
Displayed in the Exhibit Hall (Renaissance West & East)
in the right hallway
SYIS-AM POSTER COMPETITION
Poster Session I: Sunday, December 14, 4:30 pm – 6:30 pm
Poster Session II: Monday, December 15, 4:30 pm – 6:30 pm
Displayed in the front foyer outside of Renaissance West
& East. The SYIS-AM Posters will be displayed during
both Poster Session I and Poster Session II.
STUDENT-MEET-MENTOR LUNCH
Tuesday, December 16
11:30 am - 1:00 pm
Mount Vernon Square
TERMIS-AM SYIS is pleased to host the Student Meet
Mentor Lunch on Tuesday, December 16th at 11:30 am 1:00 pm during the TERMIS-AM Washington, D.C.
Meeting. The Student-Meet-Mentor Lunch gives students
and young investigators the opportunity to enjoy an
invigorating plated lunch with faculty mentors and
leaders of the Tissue Engineering and Regenerative
Medicine fields. Mentors include session chairs, members
of the Scientific Advisory Committee, and local industry
leaders. We look forward to seeing you in Washington D.C.!
STUDENT CO-CHAIRING
TERMIS-AM SYIS is pleased to announce the opportunity
for students and young investigators to serve as
co-chairs for scientific sessions at the TERMIS-AM
Washington, D.C. Meeting. This one-of-a-kind event
provides a unique platform for students and young
investigators to co-chair sessions with leading scientists
and get first-hand experience moderating scientific
discussions. At previous meetings, this event has been
hugely popular, and we hope to see several of you
co-chairing sessions at this year’s meeting.
FINAL PROGRAM
WAKE FOREST INSTITUTE FOR
REGENERATIVE MEDICINE
YOUNG INVESTIGATOR AWARD RECIPIENTS
Corin Williams
Corin Williams completed her BS and PhD in Biomedical Engineering at Boston University under
the mentorship of Prof. Joyce Wong and is currently a postdoctoral fellow in Prof. Lauren Black’s
lab at Tufts University. Her research interests are engineering approaches to understanding and
repairing congenital heart defects in the developing fetal and neonatal cardiovascular system.
Her doctoral research focused on the development of micropatterned cell sheets that mimic
the complex organization of smooth muscle cell layers in the artery. Her postdoctoral research
has largely focused on young developmental age cardiac ECM as a biomaterial for cardiac
regeneration. Corin has been supported by the American Heart Association Founder’s Affiliate
Predoctoral Fellowship, the NSF East Asia and Pacific Summer Institutes Award to conduct
research in Japan, and the NHLBI Ruth L Kirschstein NRSA individual postdoctoral fellowship.
In addition, Corin has enjoyed participating in various STEM outreach programs to high school
students while at BU and Tufts, and has been actively involved in mentoring young women who
are interested in STEM fields.
Jenny Puetzer
Jenny Puetzer, Ph.D. is a postdoctoral research fellow working with Dr. Molly Stevens at Imperial
College London. She completed her undergraduate at North Carolina State University, where
she graduated valedictorian in 2009 with a B.S. in Biomedical Engineering. At NC State, she
worked under Dr. Elizabeth Loboa, investigating the chondrogenic effect of hydrostatic pressure
and growth factor stimulation on human adipose-derived stem cells. At the completion of her
undergraduate, she received the College of Engineering Senior Scholarly Achievement Award,
and was awarded the National Science Foundation (NSF) Graduate Research Fellowship. Jenny
then pursued her Ph.D. at Cornell University under Dr. Lawrence Bonassar. Here she engineered
anatomical meniscal constructs with native-like organization, mechanical properties, and
anisotropy using high density collagen gels and mechanical stimulation. During her time at Cornell
she became interested in teaching and received a NSF Gk-12 Fellowship and a Howard Hughes
Medical Institute Junior Scientist Fellowship to further develop these skills. In 2014, Jenny was
honored to be placed (1 of 6 worldwide) on the Young Investigator Council for the journal of
Tissue Engineering. She began her postdoctoral work in August at Imperial College and received
a Whitaker International Fellowship. Here she will be developing novel functionalized polymerbased scaffolds for osteochondral repair and further investigating self-assembled collagen
fibers developed in her Ph.D. Jenny has a passion for orthopaedic research and is interested in
engineering tissues using queues from the natural developmental process in an effort to drive
native organization.
www.termis.org/am2014
11
TERMIS-AM 2014 AWARD RECIPIENTS
LIFETIME ACHIEVEMENT AWARD:
Anthony Atala, MD
Presentation Title: Regenerative Medicine: Current Concepts and Changing Trends
Presentation Date: Sunday, December 14 – 8:00 am after the Keynote presentation
Anthony Atala, MD, is the Director of the Wake Forest Institute for Regenerative Medicine, and the
W.H. Boyce Professor and Chair of the Department of Urology at Wake Forest University. Dr. Atala is a
practicing surgeon and a researcher in the area of regenerative medicine. His current work focuses on
growing new human cells, tissues and organs.
SENIOR SCIENTIST AWARD:
Molly Shoichet, PhD, FRSC, FCAE, FCAHS, FAAAS, O Ont
Presentation Title: Designer Hydrogels Influence Cell Fate
Presentation Date: Monday, December 15 – 8:00 am after the Keynote presentation
Professor Molly Shoichet is an expert in the study of Polymers for Drug Delivery & Tissue Regeneration.
She holds the Tier 1 Canada Research Chair in Tissue Engineering and is Professor of Chemical
Engineering & Applied Chemistry, Chemistry and Biomaterials & Biomedical Engineering at the
University of Toronto. She was recruited to the faculty at the University of Toronto in 1995 with
an NSERC University Faculty Award, after completing her S.B. from the Massachusetts Institute
of Technology in Chemistry (1987); her Ph.D. from the University of Massachusetts, Amherst in
Polymer Science and Engineering (1992); and spending three years as a Scientist in industry at
CytoTherapeutics Inc. Dr. Shoichet was promoted to Full Professor in 2004, after being named one
of Canada’s Top 40 under 40 (2002), and receiving CIfAR’s Young Explorer’s Award (to the top 20
scientists under 40 in Canada, 2002) and NSERC’s Steacie Research Fellowship (2003-2005).
YOUNG INVESTIGATOR AWARD:
Warren Grayson, PhD
Presentation Title: Recycling: Turning Fat into Vascularized Bone and Skeletal Muscle
Presentation Date: Monday, December 15 – 8:00 am after the Senior Scientist Award presentation
Dr. Warren Grayson joined the faculty at the Johns Hopkins’ Biomedical Engineering Department
in September 2009. Prior to this, he received his B.Sc. in Chemical & Process Engineering at The
University of the West Indies, his Ph.D. in Biomedical Engineering from Florida State University
in 2005, and completed his postdoctoral training in the Department of Biomedical Engineering
at Columbia University from 2005 to 2009. He is currently the director of the Laboratory for
Craniofacial and Orthopaedic Tissue Engineering.
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TERMIS–AM • 2014
FINAL PROGRAM
TERMIS-AM 2014 AWARD RECIPIENTS (CONTINUED)
EDUCATIONAL AWARD:
Bryan Brown, PhD
Presentation Title: Educational Initiatives within the McGowan Institute for Regenerative Medicine
Presentation Date: Tuesday, December 16 – 8:00 am after the Keynote presentation
Dr. Bryan Brown is a Research Assistant Professor with the Department of Bioengineering at
the University of Pittsburgh with a secondary appointment in Pitt’s Department of Obstetrics,
Gynecology and Reproductive Sciences. He is also the Building Interdisciplinary Research Careers
in Women’s Health Scholar (NIH K12), Magee Women’s Research Institute at the University of
Pittsburgh and an Adjunct Assistant Professor, Department of Clinical Sciences, College of
Veterinary Medicine at Cornell University.
MARY ANN LIEBERT, INC. OUTSTANDING
STUDENT AWARD:
Laura Bracaglia
Presentation Title: PPF Reinforced Pericardium as a Hybrid Material for Cardiovascular Applications
Presentation Date: Tuesday, December 16 – 8:00 am after the Educational Award presentation
Ms. Laura G. Bracaglia is a third year PhD student in the Fischell Department of Bioengineering
at the University of Maryland. Ms. Bracaglia graduated from the Georgia Institute of Technology
in 2012 with her BS in Biomedical Engineering, and began work under the mentorship of Dr. John
P Fisher in the Tissue Engineering and Biomaterials Laboratory in the spring of 2013. In 2014
Ms. Bracaglia won an American Heart Association predoctoral fellowship for her work on hybrid
biomaterial for tissue heart valve applications. While studying at the University of Maryland, Ms.
Bracaglia was awarded the Distinguished Teaching Assistant Award from the UMD Center for
Teaching Excellence, represents the bioengineering graduate program as a key ambassador, and
serves as a Vice President on the Bioengineering Graduate Student Society.
www.termis.org/am2014
13
KEYNOTES SYMPOSIA
ASTS – TERMIS Keynote Address: History and Future of
Transplant and Tissue Engineering
W.P. Andrew Lee, MD, Johns Hopkins University and
Joseph P. Vacanti, MD, Massachusetts General Hospital
Location: Grand Ballroom – Central and South Salon
Date & Time: December 13 (Sat), 4:00 pm – 5:30 pm
9:00 am – 9:15 am
Introduction to the Alliance for Regenerative Medicine (ARM)
Speaker: Tom Novak, PhD, Co-Chair, Tissue Engineering
and Biomaterials Section, ARM; VP, Corporate
Development, Cellular Dynamics International
Location: Grand Ballroom – Central and South Salon
Date & Time: December 14 (Sun), 8:00 am – 9:30 am
9:15 am – 10:30 am
Manufacturing and CMC - Translation: Commercial
Scale Manufacturing, Automation and Bioreactors
(Introduction by the moderator followed by 4 – 10-12
minute presentations and Q&A)
Oxygen Supply and Demand in Regenerative Medicine
Gregg Semenza, MD, PhD, Johns Hopkins University
Moderator: Phil Vanek, GM Cell BioProcessing,
GE Healthcare
Location: Grand Ballroom – Central and South Salon
Date & Time: December 15 (Mon), 8:00 am – 9:30 am
Presentations: Deepak Jain, CTO Tengion
Claudia Zylberberg, CEO, Akron Biotech
Jessica Carmen, BD Manager, Lonza
Laura Nikalson, CEO, Humacyte
Biomaterials for Tissue Engineering
Antonios Mikos, PhD, Rice University
Immunoengineering for Biomedical Applications
Darrell Irvine, PhD, Massachusetts Institute of Technology
Location: Grand Ballroom – Central and South Salon
Date & Time: December 16 (Tue), 8:00 am – 9:30 am
WORKSHOPS
WORKSHOP #1
The Alliance for Regenerative Medicine’s Workshop on
Commercialization Strategies for Tissue Engineered
Products
Location: Grand Ballroom – South Salon
Date & Time: December 13 (Sat), 8:30 am – 12:00 pm
Chairs: Sarah Haecker, PhD, Alliance for Regenerative Medicine
Thomas Novak, PhD, Cellular Dynamics International
The Alliance for Regenerative Medicine is dedicated
to the advancement of regenerative medicine by
representing, supporting, and engaging all stakeholders
in the field including companies, academic research
institutions, patient advocacy groups, foundations,
health insurers, and financial organizations. This ARM
sponsored workshop is designed to provide translational
and commercial insight and will highlight the some of
the current challenges and identify potential strategies
in bringing engineered tissue products to market. The
session will include panels on financing, manufacturing,
regulatory, and reimbursement and will serve as an
instructive model for early technologies and products
currently in the pipeline. Speakers will include ARM
directors, Committee and Section Co-chairs and member
organization representatives.
14
8:30 am – 9:00 am
Networking – Light Breakfast
TERMIS–AM • 2014
10:30 am – 11:00 am
Regulatory - How do we achieve better clarity on the
regulatory pathway within the U.S. and in Europe?
(Introduction by the moderator followed by 1 – 20 min
presentation and Q&A)
Introduction: Michael Werner, Co-founder & Executive
Director, Alliance for Regenerative Medicine; Health &
Life Sciences Partner, Holland & Knight
Speaker: Mark Friedman, VP of RA&QA, Axogen
11:00 am – 11:20 am
Reimbursement - Cost of Care - How and when do you
start thinking about price points for tissue-engineered
products? (One 20 - minute presentation and Q&A)
Speaker: Michael Werner, Co-founder & Executive Director,
Alliance for Regenerative Medicine; Health & Life Sciences
Partner, Holland & Knight
1 1:20 am – 12:00 pm
Financing/Partnering - Capitalizing on funding and
partnering opportunities- strategies for product developers.
(Introduction by the moderator followed by interactive panel)
Moderator: Morrie Ruffin, Co-Founder and Managing
Director, Alliance for Regenerative Medicine;
Managing Director, Adjuvant Partners
Panelists: David Smith, Secretary, Pittsburgh Tissue
Engineering Initiative – McGowan Institute for
Regenerative Medicine
George Davis, Gamma 3 LLC Kyp Sirinakis, Epidarex
FINAL PROGRAM
WORKSHOP #2
Restoring Lives and Functions for the Wounded
Warriors Workshop
Location: Grand Ballroom – Central Salon
Date & Time: December 13 (Sat), 8:00 am – 12:00 pm
Chairs: Eva Lai, PhD, Johns Hopkins University
Luis Alvarez, PhD, United States Military Academy
Session #1 Moderator: Paul Pasquina, MD, Col (Ret.)
Session #2 Moderator: Robert Christy, PhD
Speakers:
Rear Admiral Bruce Doll, DDS, PhD
Paul Pasquina, MD, Col (Ret.)
Ryan Kules
Michael Stebbins, PhD
James Gilman, MD, Major General (Ret.)
Susan Solomon, JD
Luke Burnett, PhD
Claudia Zylberberg, PhD
Narayan Iyer, PhD
Tissue engineering and regenerative medicine (TERM)
concepts present an alternative and innovative treatment
strategy for restoring the lives, functions, and the quality
of living for wounded warriors, veterans, and individuals
with polytrauma injuries. This half day pre-conference
workshop brings together clinicians, researchers, and
leaders from federal, public, and private sectors in
an engaging format to discuss the clinical challenges
and functional rehabilitation needs of the wounded
warriors, and to present the visions, challenges, and
solutions to bring emerging research and capabilities
forward. The intent of this workshop is to engage the
research community in a discussion that will enable
the researchers to design better products through an
understanding of the patients. needs and the clinical
challenges. The workshop also presents an interactive
discussion on how the federal, public, and private sectors
could develop strategies and partnerships that will help
advance TERM concepts towards product development.
Two sessions with multiple 15-min talks followed by a
45-min panel discussion are structured to allow for an
in-depth engagement with the research community,
wounded warriors, clinicians, and leaders, to explore the
impacts of the presented works and, more importantly,
to forge interdisciplinary discussions with holistic
perspectives that include scientists, engineers, clinicians,
and wounded warriors on how to address the unmet
clinical challenges of the wounded warriors, veterans,
and patients with polytrauma injuries. The first session
will cover the clinical challenges and the functional
rehabilitation needs of the wounded warriors from the
perspectives of the clinicians and wounded warriors. In
session two, leaders from the federal, public, and private
sectors will share their visions, challenges, and solutions
to bring emerging research and capabilities towards
product development. These talks will also discuss the
challenges and solutions for moving TERM concepts
forward from the bench and translational science to
clinical research and product development.
One key deliverable following the meeting will be a
collection of papers to be published within two months
as a supplemental/special issue in a peer reviewed
journal such as .Tissue Engineering.. Invited presenters
will write and contribute papers that are original, review,
and/or thought-provoking ideas. Key speakers and the
conference chairs will write a paper summarizing the
meeting and the discussions, including recommendations
for developing and delivering innovative, novel TERMbased products to treat polytrauma injuries.
WORKSHOP #3
Government Efforts on the Path to Patients for
Regenerative Medicine Therapies: A MATES Symposium
Location: Congressional A
Date & Time: December 13 (Sat), 12:00 pm – 4:00 pm
Chairs: Rosemarie Hunziker, PhD, National Institute of
Biomedical Imaging and Bioengineering (NBIB),
National Institutes of Health (NIH)
Richard McFarland, MD, PhD,
Food and Drug Administration (FDA)
The workshop will illustrate the catalytic effect of
Federal government involvement in the development
of the TE/RM field through a series of paired talks
using “case studies” that are illustrative of the interplay
between government agencies and private sector
investigators throughout the pathway from basic science
to clinical trial. The workshop will conclude with a
moderated panel discussion. Each pair of talks will
feature a “governmental supporter” followed by a “nongovernmental performer”. The government agencies
represented are all active in the Multi-agency Tissue
Engineering Sciences working group (MATES) that
serves as a forum for communication, leveraging and
co-ordination among Federal agencies whose individual
missions include activities in the Tissue Engineering/
Regenerative Medicine field.
www.termis.org/am2014
15
Introduction- (10 minutes) Richard McFarland,
Workshop co-chair, chair of MATES,
Food and Drug Administration (FDA)
Four Paired Talks- (40 minutes per pair)
Basic Science
Government Speaker: Athanassios Sambanis,
National Science Foundation (NSF)
Private Sector Speaker: Amina Qutub,
Rice University
Translational Research
Government Speaker: Martha Lundberg,
National Institutes of Health (NIH)
Private Sector Speaker: Laura Niklason,
Yale University and Humacyte, Inc.
Break (15 minutes)
Mission-supportive Translational Research
Government Speaker: Kristy Pottol,
Department of the Army (USA)
Private Sector Speaker: Benjamin Harrison,
Wake Forest University
Development of Enabling Technology
Government Speaker: Sumona Sarkar,
National Institute of Standards and Technology (NIST)
Private Sector Speaker: Padmavathy Vanguri, Lonza
Walkersville, Inc.
Panel Discussion- (50 minutes) Audience, speakers,
co-chairs, and FDA representative moderated by
Anne Plant, Workshop co-chair, NIST.
WORKSHOP #4
“Avoiding Traps” – Women in Tissue Engineering and
Regenerative Medicine Luncheon
Location: Mount Vernon Square A
Date & Time: December 13 (Sat), 12:00 pm – 4:00 pm
Co-Chairs: Alison McGuigan, PhD, University of Toronto
Milica Radisic, PhD, University of Toronto
16
TERMIS–AM • 2014
INVITED DISCUSSANTS:
Misti Ushio, Ph.D., Managing Director, Harris & Harris Group
Maureen L. Dreher, PhD, Biomedical Engineer, FDA/
Center for Devices & Radiological Health/ Office of
Science & Engineering Laboratories/ Division of Applied
Mechanics
Celia M.Witten, Ph.D., M.D.,Director, Office of Cellular,
Tissue, and Gene Therapy, Center for Biologics Evaluation
and Research, Food and Drug Administration
Megan L. Frisk, Ph.D., Associate Editor, Science
Translational Medicine
Nadya Lumelsky, Ph.D., Director, Tissue Engineering and
Regenerative Medicine Research Program, Acting Chief
of Integrative Biology and Infectious Disease Branch,
National Institute of Dental and Craniofacial Research,
National Institutes of Health
Much of the mentorship provided during academic
training targets students with academic aspirations, yet
many students in our field are choosing to contribute
to the field outside an academic setting. To transition
out of an academic setting networking and mentorship
are critical. Enabling trainees to realize full potential of
their careers, both academic and non-academic, will be
beneficial for the development of the emerging fields of
tissue engineering and regenerative medicine.
At the 2014 TERMIS-AM we will organize the second
Women in TERMIS Luncheon with the purpose of
fostering support and professional development of
young women in our field. Based on feedback from the
2013 luncheon, the focus this year will be mentorship
for non-academic careers but much of the advice is
relevant for any career and we encourage trainees
interested in all careers to participate. We are the first
TERMIS continental chapter to organize such an event.
We hope we will be able to transfer our best practices
to our sister continental chapters in Europe and AsiaPacific. We have gathered a group of leading mentors in
the tissue engineering and regenerative medicine field
who are willing to support this event. Each speaker will
spend 5-10 min presenting what they perceive major
issues/solutions are to avoiding traps in female career
development with the remaining time spent actively
engaged in discussions/questions from the audience.
Audience members will also be given the opportunity to
network with speakers and their peers at the luncheon.
FINAL PROGRAM
CONCURRENT SESSION I – DECEMBER 14 (SUN), 10:00 AM – 11:30 AM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
CONGRESSIONAL
A
CONGRESSIONAL
B
Perspectives on Tissue
Engineering & Regenerative
Medicine Education
Chair: David Williams
Decellularized Tissues
(TWIG)
Chairs: Elizabeth Cosgriff Hernandez
and Michael Detamore
Stem and Progenitor
Cell-Based Approaches
to Musculoskeletal
Tissue Therapies
(TWIG)
Chairs: Christina Celluzzi and Catherine Kuo
TERMIS-AM Industry
Committee One Day Event
Scientific Principles in
Regulatory Decision Making
Chairs: Tim Bertram, Kiki Hellman,
and Mark Van Dyke
Cardiac Tissue Engineering:
Current State and
Perspectives
(TWIG)
Chairs: Milica Radicic and Narine Sarvazyan
Introductory Comments
David Williams, Wake Forest Institute of Regenerative Medicine and Global President, TERMIS
10:00 am – 10:15 am:
Invited Speaker - Warren Grayson
Engineering Scaffolds for Craniofacial Bone
Regeneration
10:00 am – 10:15 am:
A Robust Animal Component-Free Chondrogenic
Stimulatory Medium for the Efficient Differentiation of Human Mesenchymal Progenitor Cells
A. Sampaio, C. Duronio, T. Thomas, A. Eaves, S.
Louis; STEMCELL Technologies Inc., Vancouver, BC,
CANADA, STEMCELL Technologies Inc. and Terry
Fox Laboratory, BC Cancer Agency, Vancouver,
BC, CANADA.
10:00 am – 10:05 am
Introduction – Tim Bertram, DVM, PhD, Tengion,
Inc. (Member of the AM IC)
10:00 am – 10:30 am:
Invited Speaker - Gordana Vunjak-Novakovic
Cardiac Tissue Engineering for Modeling of
Disease and Drug Screening
Strategies and Experiences at Different Institutions
Making Tissues in Class – Successes, Challenges,
and Learnings
Laura E. Niklason, PhD, Professor of Anesthesiology and Biomedical Engineering, Yale School of
Engineering and Applied Science
Development of a Regenerative Medicine Summer Program for Undergraduates
Bryan Brown, PhD, Assistant Professor, Departments of Bioengineering and Obstetrics, Gynecology and Reproductive Sciences, University
of Pittsburgh
Incorporating Regenerative Medicine in
Undergraduate and Graduate BME Curriculum:
Challenges and Opportunities
Krish Roy, PhD, Professor and Wallace H. Coulter
Distinguished Faculty Fellow, Carol Ann and
David D. Flanagan Professor and Director, Immunoengineering Research Center
Education and Training in Tissue Engineering:
The Rice Experience
Tony Mikos, PhD, Louis Calder Professor of
Bioengineering and Chemical and Biomolecular
Engineering, Director of John W. Cox Laboratory
of Biomedical Engineering and Director of Center
for Excellence in Tissue Engineering
10:15 am – 10:30 am:
Regenerative Potential Of An Acellular Xenogeneic Small Diameter Artery In Vivo
S. Wilshaw1, J. Luo1, J. Fisher1, S. Homer-Vanniasinkam2, E. Ingham1; 1University of Leeds, Leeds,
UNITED KINGDOM, 2Leeds General Infirmary,
Leeds, UNITED KINGDOM.
10:30 am – 10:45 am:
Adipose-Derived Stem Cells Mediate In Vivo Soft
Tissue Regeneration in Decellularized Adipose
Tissue Bioscaffolds
T. Han1, B. Amsden1, L. Flynn2;
1
Chemical Engineering, Queen’s University,
Kingston, ON, CANADA, 2Chemical & Biochemical
Engineering, Western University, London, ON,
CANADA.
10:45 am – 11:00 am:
Hydrogels from Demineralized and Decellularized Bone Extracellular Matrix for Bone
Regeneration
L. J. White1, O. Qutachi1, E. L. Smith2, D. Gothard2,
J. Kanczler2, S. F. Badylak3, R. O. Oreffo2, K.
M. Shakesheff1; 1University of Nottingham,
Nottingham, UNITED KINGDOM, 2University of
Southampton, Southampton, UNITED KINGDOM,
3
University of Pittsburgh, Pittsburgh, PA.
11:00 am – 11:15 am:
Partially Digested Adult Cardiac Extracellular
Matrix Promotes Neonatal Cardiomyocyte
Proliferation in Vitro
C. Williams, L. Black, III; Biomedical Engineering,
Tufts University, Medford, MA.
11:15 am – 11:30 am:
The Appropriate Microenvironment Prepared by
Decellularized Cancellous Bone Induced Ectopic
Hematopoiesis
N. Nakamura1, K. Nam1, T. Kimura1, T. Fujisato2, T.
Tsuji3, H. Iwata4, A. Kishida1; 1Tokyo Medical and
Dental University, Tokyo, JAPAN, 2Osaka Institute
of Technology, Osaka, JAPAN, 3RIKEN, Kobe,
JAPAN, 4Kyoto University, Kyoto, JAPAN.
10:15 am – 10:30 am:
Long Term Expanded Adult Myogenic Progenitor
Cells Exhibits Robust Expansion And Maintenance Of In Vivo Engraftment Capabilities
Z. Wang, D. Cheung, Y. Zhou, C. Han, T. Criswell,
S. Soker; Wake Forest Institute for Regenerative
Medicine, Winston Salem, NC, Oregon State
University, School of Chemical, Biological, and
Environmental Engineering, Corvallis, OR.
10:30 am – 10:45 am:
Making Stem Cells A Therapeutic Tool For
Restoration Of Articular Cartilage And Synovial
Joint Function
L. Wu, D. Evseenko; Orthopaedic Surgery, UCLA,
Los Angeles, CA.
10:45 am – 11:00 am:
Synergistic Effect of Tissue-Mimetic Stiffness
and Growth Factors on Zone-Specific Chondrogenic Differentiation of Human Mesenchymal
Stem Cells
T. Karimi, E. Jabbari; University of South Carolina, Columbia, SC.
10:05 am – 10:30 am
Vision Plenary, Chris Mason, Professor, University
College London
10:30 am – 10:40 am
FDA Plenary, Carolyn Wilson, PhD, Associate
Director for Research, FDA’s Center for Biologics
Evaluation and Research
10:40 am – 10:50 am
CBER Speaker, Steven Bauer, PhD, Chief, Cellular
and Tissue Therapy Branch at FDA
10:50 am – 11:00 am
CDRH Speaker, James Coburn, MS, Center for
Devices and Radiological Health at FDA
11:00 am – 11:30 am
Panel Discussion - Q & A
10:30 am – 10:45 am:
Electrical Maturation & Integration of hESCDerived Cardiomyocyte Grafts
M. A. Laflamme; Pathology, University of Washington, Seattle, WA.
10:45 am – 11:00 am:
The Age-Dependent Effects of Extracellular
Matrix Signaling in Cardiac Tissue Engineering
and Regenerative Medicine
L. D. Black, III; Department of Biomedical Engineering, Tufts University, Medford, MA.
11:00 am – 11:15 am:
Creating Biological Pumps Using Engineered
Heart Tissue
N. Sarvazyan; Pharmacology and Physiology,
The George Washington University, Washington, DC.
11:15 am – 11:30 am:
Engineered Cardiac Tissues Utilizing Human
Induced Pluripotent Stem Cell-Derived Cardiomyocytes
R. T. Tranquillo, J. S. Wendel; Biomedical
Engineering, University of Minnesota, Minneapolis, MN.
11:00 am – 11:15 am:
Cartilage Stem/Progenitor Cells Are Activated in
Osteoarthritis via Interleukin-1β/Nerve Growth
Factor Signaling
Y. Jiang, C. Hu, S. Yu, H. Ouyang, R. Tuan;
Department of Orthopaedic Surgery, University
of Pittsburgh, Pittsburgh, PA, Center for Stem
Cell and Tissue Engineering, Zhejiang University,
Hangzhou, CHINA.
11:15 am – 11:30 am
Tissue Engineered, Scaffold-Free, Human Cartilage Sheets Positively Respond to Low Oxygen
Tension Both Mechanically and Biochemically
T. Kean, A. Whitney, G. Traeger, R. Fernandes,
J. Dennis; Matrix Biology Program, Benaroya
Research Institute, Seattle, WA, Department
of Orthopaedics, University of Washington,
Seattle, WA.
www.termis.org/am2014
17
CONCURRENT SESSION II – DECEMBER 14 (SUN), 1:00 PM – 2:30 PM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
Composite Tissue-Organ
Transplantation and
Tissue Engineering
Chairs: Jason Wertheim and Anthony Atala
Naturally-derived/Inspired
Biomaterials
(TWIG)
Chairs: Jennifer Patterson and Jennie Leach
Neurogenic Differentiation
and Tissue Engineering
Strategies
(TWIG)
Chairs: Heinz Redl and Joydip Kundu
1:00 pm – 1:15 pm:
A Strategy for Reducing the Immunogenicity of
Human Renal Allografts
L. Brasile, B. Stubenitsky; BREONICS Inc., Albany,
NY, Plastic Reconstructive Surgery, Utrecht
University, Utrecht, NETHERLANDS.
1:15 pm – 1:30 pm:
Inducing Deep Tissue Angiogenesis Ex- and InVivo: Insights from Porcine Cardiac Extracellular
Matrix (pcECM)
U. Sarig, H. Sarig, E. B. Nguyen, E. d. Berardinis,
S. Chaw, S. S. Venkatraman, M. Machluf; School of
Materials Science Engineering, Nanyang Techniological University (NTU), Singapore, SINGAPORE,
Faculty of Biotechnology and Food Engineering,
Technion - Israel Institute of Technology, Haifa,
ISRAEL.
1:30 pm – 1:45 pm:
Prognostic Testing of Human Cadaveric Renal
Allografts
L. Brasile, A. Meyer, N. Henry; BREONICS Inc.,
Albany, NY.
1:45 pm – 2:00 pm:
The Effect of 28-day Ectopic Implantation on
Engineered Skeletal Muscle Units
L. Larkin, K. VanDusen, B. Syverud, J. Lee, J. Dou;
Molecular & Integrative Physiology, University of
Michigan, Ann Arbor, MI, Biomedical Engineering,
University of Michigan, Ann Arbor, MI.
2:00 pm – 2:15 pm:
Engineering The Cardiac Microenvironement For
Functional Tissue Assembly
S. Fleischer, T. Dvir; Tel-Aviv University, Tel-Aviv,
ISRAEL.
2:15 pm – 2:30 pm:
Bio-printing Mechanically-strong, Biocompatable Tissue Engineered Cell Constructs
For Nasal Reconstruction
L. A. Ruiz Cantu, C. Faris, J. Segal, J. Yang, K.
Shakesheff; Tissue engineering group, The
University of Nottingham, Nottingham, UNITED
KINGDOM, Ear, nose and throat department,
Nottingham University Hospitals, Nottingham,
UNITED KINGDOM, 2.Department of Mechanical,
Materials and Manufacturing Engineering, The
University of Nottingham, Nottingham, UNITED
KINGDOM.
18
1:00 pm – 1:30 pm:
Invited Speaker –Jennie Leach, Chemical, Biochemical & environmental Engineering, UMBC,
Baltimore, MD
Bioactive Hydrogels Based on Designer Collagens
1:30 pm – 1:45 pm:
Cellular Response of Mesenchymal Stem Cells
in Three-Dimensional Fibrin-Collagen-Calcium
Phosphate Scaffolds
C. Linsley, L. Boardman, B. Tawil; Bioengineering,
UCLA, Los Angeles, CA.
1:45 pm – 2:00 pm:
Tendon-derived Extracellular Matrix Enhances
TGF-β3 induced Tenogenic Differentiation of
Human Adipose-derived Stem Cells
G. Yang1, B. B. Rothrauff2, H. Lin2, R. Gottardi2,
R. S. Tuan2;
1
Department of Bioengineering, University
of Pittsburgh, Pittsburgh, PA, 2Department of
Orthopaedic Surgery, University of Pittsburgh,
Pittsburgh, PA.
2:00 pm – 2:15 pm:
Improving Longevity of Fibrin Sealant In Vivo
Absorption by Sustained Release of Inhibitor
B. Bordoloi1, N. Sarma2, R. Eisenberg3, T. Barbolt4,
L. Perry5;
1
Bordoloi Biotech LLC, Bridgewater, NJ, 2Surgery,
Washington University in St. Louis, Saint Louis,
MO, 3Frontier Biopharm LLC, Richmond, KY, 4TAB
Consulting, Fleetwood, PA, 5Pluris Research, Inc,
Franklin, TN.
2:15 pm – 2:30 pm:
Silk-ECM Composite Scaffolds with Anisotropic
Architecture for Cardiac Tissue Engineering
W. Stoppel, J. Rnjak-Kovacina, L. Black, III,
D. Kaplan;
Biomedical Engineering, Tufts University,
Medford, MA.
TERMIS–AM • 2014
1:00 pm – 1:15 pm:
Expansion of Neural Stem/Progenitor cells
(NSPCs) In Vitro By Manipulations of Culture
Hypoxia and Dimensionality
S. Sharee Ghourichaee, J. B. Leach; Chemical,
Biochemical, and Environmental Engineering,
University of Maryland, Baltimore County,
Baltimore, MD.
1:15 pm – 1:30 pm:
The Use Of Copper And Electric Current On Differentiation Of Adipose-derived Stem Cells
S. Salemi, L. Jaatinen, J. Hyttinen J, D. Eberli;
Tampere University, Department of Electrical
Engineering and Communications Technology,
Tampere, FINLAND, Urology, University Hospital
Zürich, Zürich, SWITZERLAND, Urology, Department of Electrical Engineering and Communications Technology, Tampere, FINLAND.
1:30 pm – 1:45 pm:
Uncrosslinked ECM based Hydrogels Promote
NSC Survival and Differentiation within Inflammatory Microenvironment
C. R. Kothapalli, K. Farrell; Chemical & Biomedical Engineering, Cleveland State University,
Cleveland, OH.
1:45 pm – 2:00 pm:
Hydrogels for Controlling Neural Stem Cell Fate
through Intracellular Redox State
K. J. Lampe; Chemical Engineering, University of
Virginia, Charlottesville, VA.
2:00 pm – 2:15 pm:
Regional Specification of Hindbrain and Spinal
Cord Neural Stem Cells derived from Human
Pluripotent Stem Cells
E. S. Lippmann, C. E. Williams, M. C. Estevez-Silva,
J. J. Coon, R. S. Ashton; Biomedical Engineering, University of Wisconsin Madison, Madison,
WI, Biomolecular Chemistry, University of
Wisconsin Madison, Madison, WI, Chemistry and
Biomolecular Chemistry, University of Wisconsin
Madison, Madison, WI.
2:15 pm – 2:30 pm:
Functional Nitrergic Neo-innervation of Denervated Colonic Explants Using Tissue Engineered
Innervated Intestinal Smooth Muscle Sheets
S. Raghavan, K. Bitar; Wake Forest Institute for
Regnerative Medicine, Winston Salem, NC.
CONGRESSIONAL
A
TERMIS-AM Industry
Committee One Day Event
Applications and Limitations
of Science in Regulatory
Decision Making
Chairs: Tim Bertram, Kiki Hellman,
and Mark Van Dyke
1:00 pm – 1:10 pm
Introductions – Kiki Hellman, PhD, Hellman
Group, LLC (member of the AMIC)
1:10 pm – 2:10 pm
Panel Discussion:
• Celia Witten, MD, PhD, Director for the Office of Cellular, Tissue and Gene
Therapies at FDA
• Trinity Bivalacqua, MD, PhD, Associate
Professor, Johns Hopkins University
• Marc Hedrick, MD, President & CEO,
Cytori, Inc.
• Geoff MacKay, President & CEO,
Organogenesis, Inc.
2:10 pm – 2:30 pm
Panel Discussion – Q & A
CONGRESSIONAL
B
Microvascular Tissue
Engineering
(TWIG)
Chairs: Steven George and Bob Tranquillo
1:00 pm – 1:30 pm:
Invited Speaker – Christopher Hughes
In Vitro Human Microtumors Supported By Perfused Microvessels: A Novel 3D Drug-screening
Platform
1:30 pm – 1:45 pm:
Vascularizing Cardiac Microtissues In Vitro from
a Single Stem Cell Source
S. George; University of California, Irvine,
Irvine, CA.
1:45 pm – 2:00 pm:
Perfusion, Sprouting, and Tubulogenesis in
3D Fibrin Gel
S. Riemenschneider, R. Tranquillo; Chemical
Engineering and Materials Science, University of
Minnesota, Minneapolis, MN.
2:00 pm – 2:15 pm:
Microenvironmental Control of Neovascularization
A. J. Putnam; Biomedical Engineering, University
of Michigan, Ann Arbor, MI
2:15 pm – 2:30 pm:
Expression of Developmental Proteins in Valve
Leaflets During In Vivo Maturation of CD133Conjugated Heart Valves
J. Williams, J. Jordan, M. Lane, A. Atala, J. Yoo;
Regenerative Medicine, Wake Forest University,
Winston-Salem, NC, Cardiothoracic Surgery,
Wake Forest University, Winston-Salem, NC.
FINAL PROGRAM
CONCURRENT SESSION III – DECEMBER 14 (SUN), 3:00 PM – 4:30 PM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
Tissue-Organ Replacement
and Preclinical Models
Chairs: Robert Guldberg, Laura Niklason
and Steven Jay
Gradients, Patterning and
Processing of Biomaterials
(TWIG)
Chairs: Elizabeth Cosgriff Hernandez
and Michael Detamore
Engineering Tissues for
In Vitro Screening and
Diagnostics Imaging I
Chair: William Wagner
3:00 pm – 3:15 pm:
Tissue Engineered Cartilage Rings and Tubes:
Building Blocks for a Tracheal Replacement
A. D. Dikina, H. A. Strobel, B. P. Lai, M. W. Rolle, E.
Alsberg; Biomedical Engineering, Case Western
Reserve University, Cleveland, OH, Biomedical
Engineering, Worcester Polytechnic Institute,
Worcester, MA, Biomedical Engineering and
Orthopaedic Surgery, Case Western Reserve
University, Cleveland, OH.
3:00 pm – 3:30 pm:
Invited Speaker – Eben Alsberg
Modular Hydrogels for Spatiotemporal Control
of Cell Function
3:30 pm – 3:45 pm:
Accelerated Vascularized Tissue Formation in
Gradient Hydrogels
B. Akar, B. Jiang, S. Somo, A. Appel, J. Larson,
E. Brey; Biomedical Engineering Department,
Illinois Institute of Technology, Chicago, IL.
3:15 pm – 3:30 pm:
Bio-Pick, Place, and Perfuse: A New Instrument
for 3D Tissue Engineering
A. Blakely, K. Manning, A. Tripathi, J. Morgan;
Center for Biomedical Engineering, Brown University, Providence, RI.
3:45 pm – 4:00 pm:
In vivo and Cell Responses to Chemically Varying Zonal Hydrogels
K. J. Walker, S. V. Madihally; Chemical Engineering, Oklahoma State University, Stillwater, OK.
3:30 pm – 3:45 pm:
Porcine Bone-Patellar Tendon-Bone (BTB)
Xenograft in a Caprine Model of ACL Repair
J. Lombardi, A. Hoonjan, A. Delossantos, N.
Rodriguez, I. Liao, H. Xu; Research and Development, LifeCell Corporation, Bridgewater, NJ.
4:00 pm – 4:15 pm:
Development of Injectable Foams for the Delivery of Autologous Mesenchymal Stem Cells
J. Robinson, M. Whitely, M. Stuebben, H. Pearce,
M. McEnery, T. Touchet, E. Cosgriff-Hernandez;
Texas A&M University, College Station, TX.
3:45 pm – 4:00 pm:
Cellular and Histological Analyses of Induced
Membrane Produced in a Caprine Chronic Tibial
Defect Model
V. Luangphakdy, C. Boehm, P. Zaveri, C. Carlson,
G. Pluhar, J. E. Bechtold, G. Muschler; Biomedical
Engineering, Cleveland Clinic, Cleveland, OH,
Department of Veterinary Population Medicine,
University of Minnesota, Saint Paul, MN, Department of Veterinary Clinical Sciences, University
of Minnesota, Saint Paul, MN, University of
Minnesota, Department of Orthopaedic Surgery,
Saint Paul, MN.
4:15 pm – 4:30 pm:
3D-Printing Enabled Osteogenic Hyperelastic
Bone Substitute
A. E. Jakus1, S. W. Jordon2, R. N. Shah1; 1Materials
Science and Engineering, Northwestern University, Chicago, IL, 2Plastic & Reconstructive Surgery,
Northwestern University, Chicago, IL.
4:00 pm – 4:15 pm:
Characterization of a Chronic Tibial Defect Model
in Goats
V. Luangphakdy, C. Boehm, H. Pan, A. Nicholson,
C. Carlson, J. E. Bechtold, G. Pluhar, G. F. Muschler;
Biomedical Engineering, Cleveland Clinic,
Cleveland, OH, Department of Veterinary Clinical
Sciences, University of Minnesota, Saint Paul, MN,
Department of Veterinary Population Medicine,
University of Minnesota, Saint Paul, MN, Department of Orthopaedic Surgery, University of
Minnesota, Minneapolis, MN.
3:00 pm – 3:15 pm:
A Metastasis-on-a-Chip System for Modeling
Colon Carcinoma Migration and Invasion In Vitro
M. Devarasetty, A. Atala, S. Soker, A. Skardal;
Institute for Regenerative Medicine, Wake Forest
Baptist Medical Center, Winston-Salem, NC.
3:15 pm – 3:30 pm:
Manipulating Hepatocellular Carcinoma Cell Fate
In Orthogonally Cross-linked Hydrogels
T. Lin, C. Lin; Department of Biomedical Engineering, Indiana University-Purdue University
Indianapolis, Indianapolis, IN.
3:30 pm – 3:45 pm:
A Tissue Engineered Tumour for Exploring
Therapy Resistance in Hypoxia
D. Rodenhizer, D. Cojocari, B. Wouters,
A. McGuigan; University of Toronto, Toronto,
ON, CANADA.
3:45 pm – 4:00 pm:
Stem Cell-based Microphysiological Osteochondral System to Model Tissue Response to
Interleukin-1β
H. Lin, T. Lozito, P. Alexander, R. Gottardi, R. Tuan;
Orthopaedic Surgery, University of Pittsburgh
School of Medicine, Pittsburgh, PA.
4:00 pm – 4:15 pm:
A 3D Chondrocyte-Macrophage Co-culture System to Study the Progression of Inflammation
in Osteoarthritis
S. Samavedi, M. Hahn; Biomedical Engineering,
Rensselaer Polytechnic Institute, Troy, NY.
4:15 pm – 4:30 pm:
Quantifying Collective Cell Migration and CellGenerated Mechanical Forces in a 3D Microtissue
Model of Wound Healing
M. Sakar1, J. Eyckmans2, V. Shenoy3, D. Eberli4,
C. S. Chen2, B. J. Nelson1; 1Institute of Robotics
and Intelligent Systems, ETH Zurich, Zurich,
SWITZERLAND, 2Biomedical Engineering, Boston
University, Boston, MA, 3Materials Science and
Engineering, University of Pennsylvania, Philadelphia, PA, 4Department of Urology, University
Hospital Zurich, Zurich, SWITZERLAND.
CONGRESSIONAL
A
TERMIS-AM Industry
Committee One Day Event
Advancing Regulatory Science
Through Expanded Education
Chairs: Tim Bertram, Kiki Hellman,
and Mark Van Dyke
3:00 pm – 3:05 pm
Introductions – Mark Van Dyke, PhD, Virginia
Tech (Member of the AM IC)
3:05 pm – 3:25 pm
Overview of the AM IC Survey – Peter Johnson,
MD, Vancive Medical Technologies (Member of
the AM IC)
3:25 pm – 3:40 pm
FDA Opportunities in Regulatory Science –
Leslie Wheelcock, MS, RN, Director, Office of Scientific & Professional Development at FDA
3:40 pm – 3:55 pm
FDA Commissioner’s Fellowship Program –
Carmen Gacchina Johnson, PhD, Biomedical Engineer, Vascular Surgery Devices Branch at FDA
3:55 pm – 4:10 pm
Industry Representative – Esin Yesilalan, MSc, Sr.
Regulatory Scientist, Voisin Consulting, Inc.
4:10 pm – 4:30 pm
Q&A
CONGRESSIONAL
B
Immunology/
Immunoengineering in
Tissue Engineering
Chairs: Hai Quan Mao
3:00 pm – 3:15 pm:
Sequential Delivery of Cytokines from Bone
Scaffolds to Promote Vascularization by M1-toM2 Transition of Human Macrophages
K. L. Spiller, G. Vunjak-Novakovic; Biomedical
Engineering, Drexel University, Philadelphia, PA,
Biomedical Engineering, Columbia University,
New York, NY.
3:15 pm – 3:30 pm:
Conformal Coating of Islets of Langerhans: a Microfluidic Approach for Transplantation without
Immunosuppression
V. Manzoli, C. Villa, A. Pileggi, R. Molano, Y. Torrente,
C. Ricordi, L. Inverardi, J. A. Hubbell, A. A. Tomei; Diabetes Research Institute, University of Miami, Miami,
FL, Pathophysiology and Transplantation, Universita’
degli Studi di Milano, Milano, ITALY, Institute of
Bioengineering, École Polythecnique Fédérale de
Lausanne, Lausanne, SWITZERLAND.
3:30 pm – 3:45 pm:
Transplant Tolerance to Fully MHC-mismatched
Islet Grafts using PLG particles
K. Hlavaty, J. Bryant, X. Zhang, W. Yap, X. Luo,
L. Shea4; Biomedical Engineering, Northwestern
University, Chicago, IL, Nephrology and Hypertension, Northwestern University, Chicago, IL, Surgery,
Organ Transplantation, Northwestern University,
Chicago, IL, 4Chemical and Biological Engineering,
Northwestern University, Chicago, IL.
3:45 pm – 4:00 pm:
CD28/CTLA-4 Expression in Peripheral Blood Tcells Induced by Allogenic Heart Valves in vitro
D. Sergeevichev, A. Subbotovskaya, A. Dokuchayeva, V. Sergeevicheva, V. Vasiliev; Academician E.N.
Meshalkin State Research Institute of Circulation
Pathology, Novosibirsk, RUSSIAN FEDERATION.
4:00 pm – 4:15 pm:
Characterization of Immune Cell Recruitment
and Polarization in Response to Extracellular
Matrix Derived Scaffolds
K. N. Sadtler, V. Z. Beachley, J. H. Elisseeff; Johns
Hopkins University, Baltimore, MD.
4:15 pm – 4:30 pm:
Biodegradable Nanoellipsoidal Artificial
Antigen Presenting Cells For Immune System
Modulation
R. Meyer, J. Sunshine, K. Perica, K. Aje, J.
Schneck, J. Green; Department of Biomedical Engineering, Johns Hopkins University, Baltimore,
MD, Department of Pathology, Johns Hopkins
University, Baltimore, MD.
4:15 pm – 4:30 pm:
Transparency In Translation: What Evidence
Do We Really Need At The Bench To Justify
Human Studies?
J. S. Robert; Arizona State University, Tempe, AZ.
www.termis.org/am2014
19
CONCURRENT SESSION IV – DECEMBER 15 (MON), 10:00 AM – 11:30 AM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
CONGRESSIONAL
A
CONGRESSIONAL
B
Commercialization and
Regulation Business Plan
Competition
(TWIG)
Chair: Chris Gemmiti
Micro/Nano
Biomaterials and Scaffold
Building Blocks
(TWIG)
Chairs: Craig Duvall and Melissa Krebs
Cardiac and Smooth
Muscle Cell Differentiation
and Function
(TWIG)
Chairs: Christina Celluzzi and Elizabeth Loboa
Drug Delivery
Chairs: Jordan Green and Kristi Anseth
Advances in Cardiovascular
Tissue Engineering Methods
(TWIG)
Chairs: Andy Putnam and Christopher Bashur
10:00 am – 11:30 am
Finalists:
BellaSono (Chaya et al)
GelSEEL (Khademhosseini et al)
NeuroGel (LoPresti and Prest)
Finalists will each have 15 minutes to present
business plans (Keynote or Powerpoint) to a
panel of judges. The winners and prizes will be
awarded at the conclusion of the session.
Honorable Mention:
Magni
Scifoger
Manuchon
Perago
Ligamend
TELO-Tox
10:00 am – 10:30 am:
Invited Speaker - Michael Detamore
Microsphere-Based Gradient Plugs for
Osteochondral Regeneration
M. S. Detamore; Chemical & Petroleum
Engineering, University of Kansas, Lawrence, KS.
10:00 am – 10:15 am:
Optimized Differentiation and Maintenance of
Cardiomyocytes Derived from Human iPSCs
D. Sirabella, W. Tang, G. Vunjak-Novakovic;
Biomedical Engineering, Columbia University,
New York, NY.
10:30 am – 10:45 am
Phosphate-Containing Poly(ethylene glycol)
(PEG) Hydrogel Nanoparticles for Prevention of
Gut-Derived Sepsis
G. Papavasiliou; Biomedical Engineering, Illinois
Institute of Technology, Chicago, IL.
10:15 am – 10:30 am:
Expression of Specific miRNAs During The
Cardiac Lineage Differentiation of Human
Pluripotent Stem Cells
S. Ku, Y. Kim, S. Kim, Y. Choi; IRMP, Medical
Research Center, Seoul Nat‘l Univ., Seoul, KOREA,
REPUBLIC OF.
10:45 am – 11:00 am:
Evaluation and Control of Alginate Microbead
Stability for Islet Encapsulation
V. A. Ibarra1, A. A. Appel1, S. I. Somo1, M. Cheng2,
S. Kao2, M. A. Anastasio3, A. Garson3, E. C. Opara4,
O. Khanna1, E. M. Brey1; 1Illinois Institute of
Technology, Chicago, IL, 2Chang Gung Memorial
Hospital, Linkou, TAIWAN, 3Washington University, St Louis, MO, 4Wake Forest Institute for
Regenerative Medicine, Winston-Salem, NC.
11:00 am – 11:15 am
HUVEC Response to Applied Flow on Micropatterned Poly(Propylene) Fumarate Scaffolds
J. K. Placone, K. Adlerz, H. Aranda-Espinoza, J.
P. Fisher; Fischell Department of Bioengineering,
University of Maryland, College Park, MD.
11:15 am – 11:30 am:
Chondrogenesis in Cell-Encapsulating
Chondroitin Sulfate/Chitosan Polyelectrolyte
Complex Microbeads for Cartilage Tissue
Engineering
E. Daley, J. Stegemann; University of Michigan,
Ann Arbor, MI.
10:30 am – 10:45 am:
BMP Mediated Crosstalk between Stem
Cell-Derived Cardiomyocytes and Polarized
Macrophages
I. Pallotta, E. Wrona, D. O. Freytes; The New
York Stem Cell Foundation Research Institute,
New York, NY.
10:45 am – 11:00 am:
Manipulation of Induced Pluripotent Stem Cells
(iPSC) with Lentivirus-based Cardiac-specific
Promoter Enhances Restoration of Cardiac
Function after Myocardial Infarction (MI)
D. Chang, Y. Wang, W. Cai, T. Okano, Y. Wang;
Institute of Advanced Biomedical Engineering
and Science, Tokyo Women’s Medical University,
Tokyo, JAPAN, Department of Pathology and
Laboratory Medicine, University of Cincinnati,
Cincinnati, OH.
11:00 am – 11:15 am:
Infarct Microenvironment Modulates Differentiation Capacity and Paracrine Signaling of
c-kit+ Cardiac Progenitor Cells
K. E. Sullivan, L. Burns, S. Sant, L. D. Black,
III; Biomedical Engineering, Tufts University,
Medford, MA.
11:15 am – 11:30 am:
Differentiated Adipose Derived Stem Cells for
Functional Smooth Muscle Bioengineering
D. Keller, S. Salemi, M. Rottmar, T. Sulser, D.
Eberli; Urology, University Hospital Zürich, Zürich,
SWITZERLAND.
20
TERMIS–AM • 2014
10:00 am – 10:15 am:
In Vivo Delivery of MYC gene to Regenerate Hair
Cells for Restoring Hearing and Balance
S. Hassan, J. Burns, E. Oliver, E. Kiell, J. Yoo,
J. Jackson, A. Atala; Wake Forest Institute for
Regenerative Medicine (WFIRM), Wake Forest
University School of Medicine, Winston Salem,
NC, National Institute on Deafness and
Other Communication Disorders, Bethesda,
MD, Department of Otolaryngology-Head and
Neck Surgery, Wake Forest University School of
Medicine, Winston Salem, NC.
10:15 am – 10:30 am:
Implant Infection Was Controlled By Sustained
Release Of Doxycyclin From A Nanofiber Coating
W. Ren, W. Song, D. Markel; Wayne State
University, Westland, MI, Orthopaedic Surgery,
Providence Hospital, Southfield, MI.
10:30 am – 10:45 am:
Cellular and Nuclear Uptake Rates and Expression of Poly(β-amino ester)-DNA Nanoparticles: a Structure-Function Analysis
C. J. Bishop, R. L. Majewski, N. S. Bhise, J. J.
Green; Biomedical Engineering, The Johns
Hopkins University School of Medicine, Baltimore, MD.
10:45 am – 11:00 am:
Dual BMP2 and VEGF Delivery from a Polycaprolactone/Collagen Sponge Scaffold to Increase
Bone Growth for Bone Flap Prefabrication
J. J. Patel, R. Fan, S. Miller, C. L. Flanagan, S. P.
Edwards, S. J. Hollister; University of Michigan,
Ann Arbor, Ann Arbor, MI.
11:00 am – 11:15 am:
Heparin Microparticle Delivery of Bone
Morphogenetic Protein-2 (BMP-2) for Bone
Regeneration
M. H. Hettiaratchi, J. S. Temenoff, R. E. Guldberg,
T. C. McDevitt; Wallace H. Coulter Department
of Biomedical Engineering, Georgia Institute of
Technology, Atlanta, GA, George W. Woodruff
School of Mechanical Engineering, Georgia
Institute of Technology, Atlanta, GA.
11:15 am – 11:30 am:
Biodegradable Polymeric Nanoparticles Effectively Deliver DNA and siRNA for Regenerative
Medicine
J. Green; Biomedical Engineering, Johns Hopkins
University, Baltimore, MD.
10:00 am – 10:15 am:
Chemical Surface Modification of 3D Printed
Poly(Propylene Fumarate) Vascular Grafts
A. Melchiorri1, N. Hibino2, J. Fisher3; 1University
of Maryland - College Park, College Park, MD,
2
Nationwide Children’s Hospital, Columbus, OH,
3
Fischell Department of Bioengineering, University of Maryland - College Park, College Park, MD.
10:15 am – 10:30 am:
A Cellularized Electrospun Vascular Scaffold for
Blood Vessel Regeneration
Y. Ju, H. Ahn, C. Kim, J. Lee, J. J. Yoo, A. Atala, S. Lee;
Wake Forest Institute for Regenerative Medicine,
Wake Forest School of Medicine, Winston-Salem, NC.
10:30 am – 10:45 am:
Development of an A-Cellular Vascular Graft
Capable of Complete Host Integration
M. Koobatian1, R. Smith2, S. Row3, S. Andreadis3,
D. Swartz4; 1Physiology and Bio-Physics, State
University of New York at Buffalo, buffalo, NY,
2
Bio-Medical Engineering, State University of
New York at Buffalo, Buffalo, NY, 3Chemical and
Biological Engineering, State University of New
York at Buffalo, buffalo, NY, 4Pediatrics, State
University of New York at Buffalo, Buffalo, NY.
10:45 am – 11:00 am:
Tissue-engineered Aortic Heart Valve Based On
Novel Tubular Tissue Design
Z. H. Syedain, J. M. Reimer, J. B. Schmidt, R. T.
Tranquillo; Dept of Biomedical Engineering,
University of Minnesota, Minneapolis, MN.
11:00 am – 11:15 am:
Dual and Controlled Delivery of Fibroblast
Growth Factors from Poly(ester amide) Fibers
for Therapeutic Angiogenesis
S. Said1, J. Pickering2, K. Mequanint3; 1Biomedical
Engineering Graduate Program, The University
of Western Ontario, London, ON, CANADA, 2Medicine (Cardiology), Biochemistry, and Medical
Biophysics, The University of Western Ontario,
London, ON, CANADA, 3Chemical and Biochemical
Engineering and Biomedical Engineering Graduate Program, The University of Western Ontario,
London, ON, CANADA.
11:15 am – 11:30 am:
Use Of Three-dimensional Tissue Engineered
Cardiac Fibers To Assess Cardiac Contractility
D. Brooks1, R. Idrees2, A. Chandra1, N. Sarvazyan3,
N. Posnack3; 1Biomedical Engineering, George
Washington University, Washington, DC, 2George
Washington University, Washington, DC, 3Pharmacology & Physiology, George Washington
University, Washington, DC.
FINAL PROGRAM
CONCURRENT SESSION V – DECEMBER 15 (MON), 1:00 PM – 2:30 PM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
CONGRESSIONAL
A
CONGRESSIONAL
B
Biofabrication and
Bioreactors
(TWIG)
Chairs: David Dean, George J. Christ,
and Phil Levesque
Implants and Host Response
to Biomaterials
(TWIG)
Chairs: Kacey Marra and Melissa Krebs
Stem Cell Function,
Migration and Trafficking
(TWIG)
Chairs: Danielle Benoit and Elizabeth Loboa
Why Standards Are Critical
for Getting TEMPs to Market
Chairs: Carl Simon Jr., David Kaplan,
and Richard McFarland
Dental and Craniofacial
Regeneration I
(TWIG)
Chairs: Peter Ma and Eva Lai
1:00 pm – 1:30 pm:
Invited Speaker – Jennie Leach; Chemical,
Biochemical & Environmental Engineering, UMBC
Analysis of Cell Shape and Signaling Response
to Engineered 3D Environments
1:00 pm – 1:15 pm:
Engineering Pluripotent Stem Cell Colony Morphology to Enhance Lineage Specific Differentiation
M. Maldonado, K. Low, L. Wong, G. Ico, R. Luu, M.
Ramos, J. Nam; Bioengineering, University of
California, Riverside, CA.
1:00 pm – 1:15 pm:
High-throughput Robotic Fabrication of
Stem Cell Spheroids Using Gellan Gum Based
Hydrogels
V. SURAMPUDI, X. Wen; Chemical Engineering,
Virginia Commonwealth University, RICHMOND, VA.
1:15 pm – 1:30 pm:
Rapid 3D printing Anatomically Shaped Bone
Scaffolds Using Novel Molding and Perfusion
Techniques
Y. Pang, Y. Yao, B. Grottkau; Orthopaedics,
Massachusetts General Hospital, Boston, MA.
1:30 pm – 1:45 pm:
Bioreactor Design for Real-time Conditioning
and Monitoring of Tissue Engineered Muscle
Grafts
C. A. Cook, P. Y. Huri, B. P. Ginn, J. P. Temple, J.
E. Gilbert, H. Mao, W. L. Grayson; Biomedical
Engineering, Johns Hopkins University,
Baltimore, MD.
1:45 pm – 2:00 pm:
Biofabrication of Tissue Constructs for
Craniomaxillofacial Reconstruction
C. Kengla, Y. Seol, H. Kim, H. Kang, S. Lee,
J. J. Yoo, A. Atala; Wake Forest Institute for
Regenerative Medicine, Winston-Salem, NC.
2:00 pm – 2:15 pm:
Development of Parallel Pulsatile Flow
Bioreactors for 3D Printed Tissue Engineered
Heart Valve Conditioning
D. Y. Cheung, L. A. Hockaday, B. Duan, K. Li, A.
Kaldany, J. T. Butcher; Biomedical Engineering,
Cornell University, Ithaca, NY.
2:15 pm – 2:30 pm:
Cultivation of Functional Tendon Graft Material
in a Novel Bioreactor
D. W. Youngstrom, J. G. Barrett, I. Rajpar, D. L.
Kaplan; Marion duPont Scott Equine Medical
Center, Virginia Tech, Leesburg, VA, Tissue
Engineering Resource Center, Tufts University,
Medford, MA.
1:30 pm – 1:45 pm:
In Vivo Evaluation of a Cortical-Bone-Mimetic
Resorbable Matrix in a Load-Bearing Segmental
Defect Model
E. Jabbari; University of South Carolina,
Columbia, SC.
1:45 pm – 2:00 pm:
More Than A Decade Of Ongoing Conflict:
Application And Merger Of Traditional
Reconstructive Techniques With Regenerative
Medicine Therapies In Traumatic Extremity
Reconstruction- Introduction Of The Hybrid
Reconstructive Elevator
I. L. Valerio1, M. Fleming2; 1Plastic and
Reconstructive Surgery, Walter Reed National
Military Medical Center, Bethesda, MD,
2
Orthopedic Surgery, Walter Reed National
Military Medical Center, Bethesda, MD.
2:00 pm – 2:15 pm:
In Vivo Osteogenic Environment Promoted by
Polyanionic Collagen Matrices
L. B. Rocha, M. M. Cintra, K. R. Pucci; Pathology,
Genetics and Ecology, Triângulo Mineiro Federal
University, Uberaba - MG, BRAZIL.
2:15 pm – 2:30 pm:
Growth Factor Loaded Keratin Hydrogels for
Treatment of a Sheet-like VML Injury in Mice
H. B. Baker1, J. A. Passipieri1, M. Siriwardane1, C.
Okoukoni1, C. Stewart2, M. Ellenburg3, L. Burnett3,
S. Tomblyn3, G. J. Christ1; 1Wake Forest University,
Winston-Salem, NC, 2University of Virginia,
Charlottesville, VA, 3Keranetics, LLC, WinstonSalem, NC.
1:15 pm – 1:30 pm:
Reducing Uncertainty in the Evaluation of Stem
Cell Colonies
M. Halter, S. Lund, Y. Li-Baboud, A.P. Peskin, P.
Bajcsy, D.J. Hoeppner, A. L. Plant; National Institute of Standards and Technology, Gaithersburg,
MD, Lieber Institute for Brain Development,
Baltimore, MD.
1:30 pm – 1:45 pm:
In Vitro Analysis of Mesenchymal Stem Cell
Trafficking
R. Mifflin, A. Prasai, D. Herndon, C. Finnerty;
Surgery, University of Texas Medical Branch,
Galveston, TX.
1:45 pm – 2:00 pm:
Dexamethasone And Azathioprine Promote
Cytoskeleton Changes And Affect Msc Migratory
Behavior
N. Schneider, F. d. Gonçalves, F. O. Pinto, P. L. Lopes,
A. B. Araújo, M. L. Lamers, A. H. PAZ; FEDERAL
UNIVERSITY OF RIO GRANDE DO SUL- PORTO ALEGREBRAZIL, PORTO ALEGRE, BRAZIL, b.Graduate Program
in Gastroenterology and Hepatology Sciences, Porto
Alegre Universidade Federal d, FEDERAL UNIVERSITY
OF RIO GRANDE DO SUL- PORTO ALEGRE- BRAZIL,
PORTO ALEGRE, BRAZIL, EMBRIOLOGY AND CELL DIFFERENTIATION LABORATORY, CLINICAL HOSPITAL OF
PORTO ALEGRE- RESEARCH CENTER- MORPHOLOGICAL
SCIENCES-FEDERAL UNIVERSITY OF RIO GRANDE DO
SUL- PORTO ALEGRE- BRAZIL, PORTO ALEGRE, BRAZIL,
CLINICAL HOSPITAL OF PORTO ALEGRE- RESEARCH
CENTER- PORTO ALEGRE- BRAZIL, PORTO ALEGRE,
BRAZIL, UMBILICAL CORD BLOOD BANK, CLINICAL
HOSPITAL OF PORTO ALEGRE- CLINICAL RESEARCH
CENTER- PORTO ALEGRE- BRAZIL, PORTO ALEGRE,
BRAZIL, MORPHOLOGICAL SCIENCES DEPARTMENTFEDERAL UNIVERSITY OF RIO GRANDE DO SUL- PORTO
ALEGRE- BRAZIL, PORTO ALEGRE, BRAZIL.
2:00 pm – 2:15 pm:
Consistent enhancement of Mesenchymal Stem
Cell (MSC) function by IFN-gamma and TNF-alpha
treatment in vitro
I. Farrance, L. Lock, P. Baraniak, J. Rowley; RoosterBio, Inc., Frederick, MD.
2:15 pm – 2:30 pm:
Inhibitors of Tumor Necrosis Factor alpha or
Cyclooxygenase-2 Block Mesenchymal Stem Cell
Homing to Muscle
P. Tebebi, S. Burks, S. Kim, R. Williams, B. Nguyen, V.
Frenkel, J. Frank; NIH Clinical Center, Bethesda, MD,
Catholic University of America, Bethesda, MD.
Standards and the Review Process
Malcolm Moos Jr., FDA, White Oak, MD.
Standards for Characterizing Collagen
S. Voytik-Harbin, Weldon School of Biomedical
Engineering, Purdue University, West Lafayette, IN
Development of the ASTM Standard Guide for
in vivo Assessment of Implantable Devices
Intended to Repair or Regenerate Articular
Cartilage
B. Boyan, Biomedical Engineering, Virginia
Commonwealth University, Richmond, VA.
Standard Guide for Measuring Osteogenic
Differentiation In Vitro
L. Kuhn, L. Charles, G. Gronowicz; University of
Connecticut Health Center, Farmington, CT
Complexities in Developing Reference Materials
for TERM
Carl Simon Jr., Biosystems & Biomaterials
Division, National Institute of Standards &
Technology, Gaithersburg, MD.
Use of Standards in X-Repair 510k Submission
A. Ratcliffe; Synthasome, Inc, San Diego, CA.
1:00 pm – 1:15 pm:
Tailoring Porous Degradable Biomaterials For
Guided Tissue Regeneration In Dental Tissue
Engineering
R. A. Gangolli, P. I. Lelkes, M. Yang; Bioengineering,
Temple University, Philadelphia, PA, Endodontology,
Temple University, Philadelphia, PA.
1:15 pm – 1:30 pm:
Space Maintenance and New Bone Formation
with Polyurethane Biocomposites in a Canine
Saddle Defect
A. D. Talley, K. N. Kalpakci, K. J. Zienkiewicz, J.
C. Wenke, S. A. Guelcher; Chemical Engineering,
Vanderbilt University, Nashville, TN, Medtronic Spinal and Biologics, Memphis, TN, US Army Institute of
Surgical Research, Fort Sam Houston, TN.
1:30 pm – 1:45 pm:
Poly (glycerol sebacate) Elastomer Supports Bone
Regeneration by Its Mechanical Properties Similar
to Osteoid Tissue
S. Zaky, J. Gao, K. Lee, A. Almarza, Y. Wang, C. Sfeir;
Oral Biology, Center for Craniofacial Regeneration,
Pittsburgh, PA, BioEngineering, University of Pittsburgh, Pittsburgh, PA.
1:45 pm – 2:00 pm:
Effect of Statin with Biphasic Calcium Phosphate
on Differentiation and Mineralization of Human
Dental Pulp Cells
S. AbdulQader, I. Ab Rahman, T. Kannan, H. Ismail,
Z. Mahmood; School of dental sciences, Kubang
Kerian, MALAYSIA, School of Materials and Minerals
Resource Engineering, Nibong Tebal, MALAYSIA.
2:00 pm – 2:15 pm:
Nano-drop Printing of SDF-1β on DermaMatrix
Augments BMP-2-induced Repair of Critical Size
Mouse Calvarial Defects
J. Cray1, S. A. Herberg2, G. Kondrikova2, S.
Periyasamy-Thandovan2, R. N. Howie2, M. Elsalanty3,
P. Campbell4, L. Weiss5, W. D. Hill, II2; 1Department
of Oral Health Sciences, Medical University of
South Carolina, Charleston, SC, 2Cellular Biology &
Anatomy, Georgia Regents University, Augusta, GA,
3
Oral Biology, Georgia Regents University, Augusta,
GA, 4Institute for Complex Engineering Systems,
Carnegie Mellon University, Pittsburgh, PA, 5Robotics
Institute, Carnegie Mellon University, Pittsburgh, PA.
2:15 pm – 2:30 pm:
A Biomimetic 3D Model for Tooth Regeneration
E. E. Smith, G. Camci-Unal, N. R. Schiele, C. K. Kuo,
A. Khademhosseini, P. C. Yelick; Sackler School of
Biomedical Sciences, Tufts University School of
Medicine, Boston, MA, Wyss Institute for Biologically
Inspired Engineering, Harvard-MIT, Cambridge,
MA, Department of Biomedical Engineering, Tufts
University, Medford, MA, Tufts University School of
Dental Medicine, Boston, MA.
www.termis.org/am2014
21
CONCURRENT SESSION VI – DECEMBER 15 (MON), 3:00 PM – 4:30 PM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
CONGRESSIONAL
A
CONGRESSIONAL
B
Strategies for
Innervation, Nerve Repair
and Integration
(TWIG)
Chairs: Shelly Sakiyama-Elbert and
Jeffrey R. Capadona
Engineered Biomaterials
to Regulate Cell Fate and
Function I
(TWIG)
Chairs: Eben Alsberg and Jennie Leach
Engineering Tissues for
In Vitro Screening and
Diagnostics Imaging II
Chair: William Wagner
Skin, Wound Healing and
Inflammation
(TWIG)
Chairs: Mark Van Dyke and Grace Zhang
Dental and Craniofacial
Regeneration II
(TWIG)
Chairs: Peter Ma and Eva Lai
3:00 pm – 3:15 pm:
Microfabricated Perfusable Cardiac Biowire:
A Platform That Mimics Native Cardiac Bundle
Y. Xiao1, B. Zhang1, H. Liu2, Y. Sun2, C. Simmons2,
M. Radisic1; 1Department of Chemical Engineering & Applied Chemistry, University of Toronto,
Toronto, ON, CANADA, 2Department of Mechanical
& Industrial Engineering, University of Toronto,
Toronto, ON, CANADA.
3:00 pm – 3:15 pm:
Engineering the Keratinocyte Microenvironment:
Harnessing Topography to Direct Cellular Function
A. L. Clement, J. E. Molignano, T. J. Moutinho, Jr,
G. D. Pins; Biomedical Engineering, Worcester
Polytechnic Institute, Worcester, MA.
3:00 pm – 3:15 pm:
Chemotactic Attraction of Neural Stem/Progenitor Cells through Sustained Release of Stromal
Derived Factor-1
D. Dutta, C. Fauer, R. W. Sirianni, S. E. Stabenfeldt;
School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, Banner
Neurological Institute, Phoenix, AZ.
3:15 pm – 3:30 pm:
Tissue Engineered Nerve Grafts with Aligned
Axonal Tracts Facilitate Regeneration Across 5cm
Peripheral Nerve Lesions in Swine
D. K. Cullen, M. I. Ezra, K. D. Brown, J. Dutton, L. A.
Struzyna, K. S. Katiyar, J. P. Morand, J. A. Wolf, H.
Ledebur, Jr., D. H. Smith; Neurosurgery, University
of Pennsylvania, Philadelphia, PA, Axonia Medical,
Inc, Kalamazoo, MI.
3:30 pm – 3:45 pm:
Gene Therapy For Spinal Cord Injury Using
Hypoxia-inducible Neuron-specific VEGF
Expression System
Y. Yun, D. Yoon, M. Lee, H. Yoon; Brain Korea 21
PLUS Project for Medical Science, Yonsei University,
seoul, KOREA, REPUBLIC OF, Department of Neurosurgery, Spine and Spinal Cord Institute, Yonsei
University, seoul, KOREA, REPUBLIC OF, Department
of Bioengineering, College of Engineering, Hanyang University, Yonsei University, seoul, KOREA,
REPUBLIC OF.
3:45 pm – 4:00 pm:
Electrospun Micro-fibrous Conduits Composed Of
Poly(l-lactic Acid) And Elastin-laminin Mimicking
Protein For Peripheral Nerve Regeneration
S. Kakinoki, M. Nakayama, T. Moritan, T. Yamaoka;
Department of Biomedical Engineering, National
Cerebral and Cardiovascular Center Research
Institute, Suita, Osaka, JAPAN, Department of
Clinical Engineering, Faculty of Medical Engineering, Suzuka University of Medical Science, Suzuka,
Mie, JAPAN.
3:00 pm – 3:30 pm:
Invited Speaker – Kacey Marra, Plastic Surgery,
University of Pittsburgh
Interim Analysis of Nerve Regeneration Using
Novel Tissue-Engineered Nerve Guides in a
Non-Human Primate Model
3:30 pm – 3:45 pm:
Multifunctionalized Silk Conduit as New
Promising Materials for Nerve Guidance
P. VIGNERON1, T. DINIS1, G. VIDAL1, D. BRESSON1, J.
DUVAL1, D. KAPLAN2, C. EGLES1; 1Biomécanique et
Bioingénierie, UTC-CNRS UMR7338, Compiegne,
France, 2Biomedical engineering, TUFTS
University, Medford, Ma.
3:45 pm – 4:00 pm:
Regulation of Mesenchymal Stem Cell
Differentiation towards Valve Interstitial Cell
Phenotypes in Three-Dimensional Hybrid
Hydrogels with Covalently Immobilized Growth
Factors
B. Duan, S. Das, C. Xu, L. A. Hockaday, J.
T. Butcher; Biomedical Engineering, Cornell
University, Ithaca, NY.
4:00 pm – 4:15 pm:
Influence of Sparse Electrospun Fibers on the
Differentiation of Mesenchymal Stem Cells in
Collagen Gels
P. Thayer1, D. Plessl1, E. Tong1, S. Verbridge1,
L. Dahlgren1, S. Guelcher2, A. Goldstein1;
1
Virginia Tech, Blacksburg, VA, 2Vanderbilt
University, Nashville, TN.
4:15 pm – 4:30 pm:
Development And Characterization Of A Cardiac
Ecm-derived Porous Scaffold As An In Vitro
Model System
V. Russo1, L. Flynn2; 1Queen’s University, Kingston,
ON, CANADA, 2University of Western Ontario,
London, ON, CANADA.
4:00 pm – 4:15 pm:
Directing Ventral Interneuron Differentiation
from Embryonic Stem Cells
S. E. Sakiyama-Elbert, H. Xu; Biomedical Engineering, Washington University, St. Louis, MO.
4:15 pm – 4:30 pm:
Restoring Brain Circuitry Using Novel
Biomaterial Strategies to Encapsulate
Micro-Tissue Engineered Neural Networks
J. P. Harris, L. A. Struzyna, P. L. Murphy,
D. K. Cullen; Neurosurgery, Center for Brain
Injury & Repair, University of Pennsylvania,
Philadelphia, PA.
22
TERMIS–AM • 2014
3:15 pm – 3:30 pm:
Non-Invasive Image-Based Assessment of
Human Induced Pluripotent Stem Cell-Derived
Cardiomyocytes
C. M. Heylman1, R. Datta1, Y. Kurokawa1, D. D.
Tran1, B. R. Conklin2, E. Gratton1, S. C. George1;
1
University of California, Irvine, Irvine, CA, 2Gladstone Institutes, San Francisco, CA.
3:30 pm – 3:45 pm:
A Human iPS-derived In Vitro Model of 3D
Vascularized Cardiac Muscle
Y. Kurokawa1, D. Tran1, M. Moya1, A. Sobrino1, L.
Alonzo1, C. Heylman1, C. Tu1, L. Lock1, B. Conklin2,
C. Hughes1, S. George1; 1University of Califronia,
Irvine, Irvine, CA, 2Gladstone Institutes, San
Francisco, CA.
3:45 pm – 4:00 pm:
Stem Cell and Matrix-based Therapies Differentially Enhance Beating Dynamics in an In Vitro
Human Induced Pluripotent Stem Cell-derived
Cardiomyocyte Model
M. B. Robinson, T. Petrie, V. Spandler, W. D. Boyd,
C. S. Sondergaard; Department of Cardiothoracic
Surgery, School of Medicine, University of California Davis, Sacramento, CA.
4:00 pm – 4:15 pm:
Tissue And Organ Microarrays For Probing
Extracellular Matrix-derived Materials
V. Z. Beachley, K. Sadtler, H. Jacobs, M. Blatchley,
J. Elisseeff; Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD.
4:15 pm – 4:30 pm:
Integration of 3-D Organoid Bioprinting and
Microfluidic Device Technology for Functional
Primary Cell-Based Liver-on-a-Chip Operation
A. Skardal, I. Mead, M. Devarasetty, H. Kang,
T. Shupe, S. Lee, J. D. Jackson, C. E. Bishop, J. J.
Yoo, S. Soker, A. Atala; Institute for Regenerative
Medicine, Wake Forest Baptist Medical Center,
Winston-Salem, NC.
3:15 pm – 3:30 pm:
Military-lead Novel Regenerative Medicine
Case Study: Spray Skin Epidermal Regenerate
in Conjunction with Dermal Regenerate for
Reconstruction of Full Thickness Traumatic Soft
Tissue Injuries
I. L. Valerio, M. Fleming; Plastic and Reconstructive Surgery, Walter Reed National Military
Medical Center, Bethesda, MD, Orthopedic Surgery,
Walter Reed National Military Medical Center,
Bethesda, MD.
3:30 pm – 3:45 pm:
In Vivo Evaluation Of Oxygen Releasing Suture
Material For Improved Wound Healing In Hypoxic
Environments
R. Inglin, B. Harrison, L. Brügger, T. Sulser, D.
Candinas, D. Eberli; Labor of Tissue Engineering
and Regenerative Medicine, Urology, University
Hospital Zurich, Zurich, SWITZERLAND, Institute for
Regenerative Medicine, Winston-Salem, NC, Clinic
of Visceral Surgery and Medicine, Bern University
Hospital, Bern, SWITZERLAND, Clinic of Urology,
University Hospital Zurich, Zurich, SWITZERLAND.
3:45 pm – 4:00 pm:
Stem Cells For Wound Healing With Integra As
A Carrier
P. M. Pham, M. M. Mujadzic, M. Mujadzic, W. D.
Hill, E. F. Ritter; Surgery, Section of Plastic & Reconstructive Surgery, Georgia Regents University,
Augusta, GA, Cellular Biology & Anatomy; Orthopaedic Surgery; Institute for Regenerative and
Reparative Medicine, Georgia Regents University;
Charlie Norwood VAMC, Augusta, GA.
4:00 pm – 4:15 pm:
Oxygenating Chitosan-Perfluorocarbon Hydrogel
Dressings for Accelerated Wound Healing
N. Fountas-Davis, P. S. Patil, N. D. Leipzig; Chemical and Biomolecular Engineering, University of
Akron, Akron, OH.
4:15 pm – 4:30 pm:
Burn Injury Induced Adipose Derived Stem
Cells (ASCs) Inflammation Decreases Under Cell
Culture Condition
A. Prasai, R. Mifflin, A. El ayadi, D. Herndon, C.
Finnerty; University of Texas Medical Branch,
Galveston, TX, Surgery-Burn - Shrine - Research,
University of Texas Medical Branch, Galveston, TX,
Surgery-Burn, University of Texas Medical Branch,
Galveston, TX.
3:00 pm – 3:15 pm:
Extensively Expanded Auricular Chondrocytes
Form Neocartilage In Vivo
A. Tseng, I. Pomerantseva, M. J. Cronce, A.
M. Kimura, C. M. Neville, M. A. Randolph, J. P.
Vacanti, C. A. Sundback; Center for Regenerative Medicine, Massachusetts General Hospital,
Boston, MA.
3:15 pm – 3:30 pm:
Use Of Autologous Adipose Stem Cells To
Reconstruct 13 Patient Cases With Craniomaxillofacial Hard-tissue Defects
S. Miettinen; BioMediTech, University of Tampere,
Tampere, FINLAND.
3:30 pm – 3:45 pm:
Whole Tooth Regeneration Using Decellularized
Tooth Bud Scaffolds
W. Zhang, B. Vasquez, P. Yelick; Tufts University,
School of Dental Medicine, Boston, MA.
3:45 pm – 4:00 pm:
Localized Low Dose rhBMP-2 is Effective at
Promoting Bone Regeneration in a Pre-clinical
Mandibular Segmental Defect Model
P. Carlisle, D. Silliman, A. Talley, D. Tucker, R.
Hale, S. Guelcher, P. Brown Baer; Dental Trauma
Research Detachment, US Army Institute of
Surgical Research, Ft. Sam Houston, TX, School of
Engineering, Vanderbilt University, Nashville, TN.
4:00 pm – 4:15 pm:
Hypoxia Induces Undifferentiated Phenotype Of
Oral Keratinocytes In Vitro
H. Kato, K. Izumi, A. Shiomi, A. Uenoyama, S.
Kuo, S. Feinberg, T. Maeda; Oral and Maxillofacial
Surgery, University of Michigan, Ann Arbor,
MI, Biomimetics, Niigata University School of
Dentistry, Niigata, JAPAN, Dental Educational Research Development, Niigata University School of
Dentistry, Niigata, JAPAN, Oral Anatomy, Niigata
University School of Dentistry, Niigata, JAPAN.
4:15 pm – 4:30 pm:
Development of an Animal Model to Tissue
Engineer Human Lips
S. Feinberg, I. Makovey, W. Zhang, M. Urbanchek;
Oral and Maxillofacial Surgery, University of
Michigan, Ann Arbor, MI.
FINAL PROGRAM
CONCURRENT SESSION VII – DECEMBER 16 (TUES), 10:00 AM – 11:30 AM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
CONGRESSIONAL
A
CONGRESSIONAL
B
Ocular Tissue Regeneration
(TWIG)
Chairs: Shay Soker and Alonzo Cook
Engineered Biomaterials
to Regulate Cell Fate and
Function II
(TWIG)
Chairs: Craig Duvall and Kacey Marra
Tools and Platforms for
Stem Cell Therapies
(TWIG)
Chairs: Li Zeng and Danielle Benoit
Regeneration of Composite
Musculoskeletal Tissues
(TWIG)
Chairs: Tracy Criswell and Johnna Temenoff
Computational Modeling,
Systems Biology, and
Physical Parameters in
Tissue Development
Chairs: Kim Stroka, Kacey Marra, and
Hai-Quan Mao
10:00 am – 10:15 am:
Scalable Enzyme-free Protocols For The
Isolation And Maintenance Of Human Induced
Pluripotent Stem Cells (hiPSC) Without Manual
Colony Picking Or Scraping
E. Hadley, J. Norberg, W. Chang, A. Ng, A. Hunter,
A. Eaves, T. Thomas, S. Louis; STEMCELL Technologies Inc., Vancouver, BC, CANADA.
10:00 am – 10:30 am:
Invited Speaker – Robert Guldberg, Georgia
Institute of Technology, Atlanta, GA
Preclinical Models And Regenerative Strategies
For Composite Limb Trauma
10:00 am – 10:15 am:
Cell Cycle Transition in Human Embryonic Stem
Cells During Self-Renewal and Differentiation
K. Task, I. Banerjee; Chemical Engineering,
University of Pittsburgh, Pittsburgh, PA.
10:30 am – 10:45 am:
Mechanism Of Lysophosphadic Acid Mediates
Fibrosis In Injured Joints
L. Wu, D. Evseenko; Orthopaedic Surgery, UCLA,
Los Angeles, CA.
10:15 am – 10:30 am:
Perfusion Driven Shear Stress Leads to
Self-Organization of Bioengineered Livers
E. C. Moran, P. M. Baptista, J. L. Sparks, S. Soker;
Wake Forest Institute for Regenerative Medicine,
Wake Forest University, Winston-Salem, NC,
Aragon Health Sciences Institute, University of
Zaragoza, Zaragoza, SPAIN, Chemical, Paper
and Biomedical Engineering, Miami University,
Oxford, NC.
10:00 am – 10:30 am:
Invited Speaker – Monika Kozak Ljunggren,
Integrative Regenerative Medicine Centre
Linköping University
Biomimetic Materials for Cornea Regeneration The Route from Bench to Bedside
10:30 am – 10:45 am:
Decellularized Retinal Matrix: Biomimetic
Substrate for Human Retinal Progenitor Cells
J. Kundu, A. Michaelson, P. Baranov, M. Young,
R. Carrier; Chemical Engineering, Northeastern
University, Boston, MA, Schepens Eye Research
Institute, Boston, MA.
10:45 am – 11:00 am:
Towards Regeneration Of The Optic Nerve By
Culturing Stem Cell Derived Retinal Ganglion
Cells On Collagen Vitrigel Substrate
X. Wang, V. Sluch, D. J. Zack, J. H. Elisseeff;
Wilmer Eye Institute, Baltimore, MD, Department
of Neuroscience, Baltimore, MD.
11:00 am – 11:15 am:
Matrix Proteins and Retina Development in a
3D in vitro System
H. Wang, R. R. Kaini, T. A. Burke, D. J. Golden,
A. J. Johnson; Ocular Trauma, US Army Institute
of Surgical Research, JBSA Fort Sam Houston,
TX, Cherokee Nation Businesses, JBSA Fort Sam
Houston, TX.
11:15 am – 11:30 am:
3d Corneal Stromal Tissue Equivalent Based On
Corneal Stromal Stem Cells And Multi-layered
Silk Film Architecture
C. Ghezzi, D. Kaplan, J. Funderburgh; Department
of Biomedical Engineering, Tufts University,
Medford, MA, Department of Ophthalmology,
University of Pittsburgh School of Medicine,
Pittsburgh, PA.
10:00 am – 10:30 am:
Invited Speaker – Craig Duvall
Gene Silencing within ROS Degradable Scaffolds
to Modulate Wound Healing
C.L. Duvall, J.R. Mrtin, C.E. Nelson, M.K. Gupta,
S.A. Guelcher, J.M. Davidson; Biomedical Engineering, Vanderbilt University, Nashville, TB,
Chemical and biomolecular Engineering, Vanderbilt University, Nashville, TN, Dept. of Pathology,
Microbiology and Immunology, Vanderbilt
University, Nashville, TN.
10:30 am – 10:45 am:
Role for Stiffness in Vascular Fate
L. Wong1, D. Glaser1, Y. Choi2, J. Pegan3, A. Engler4,
J. Sim5, B. Pruitt5, M. Khine3, K. McCloskey1;
1
University of California, Merced, Merced, CA,
2
Kolling Institute of Medical Research, University
of Sydney, St Leonards, AUSTRALIA, 3University
of California, Irvine, Irvine, CA, 4University of
California, San Diego, San Diego, CA, 5Stanford
University, Stanford, CA.
10:45 am – 11:00 am:
Optimization of Surface-Modified Biodegradable
Scaffolds for Mesenchymal Stem Cell Adhesion
and Differentiation
K. M. Ferlin1, D. S. Kaplan2, J. P. Fisher1;
1
Fischell Department of Bioengineering, University of Maryland, College Park, MD, 2Center for
Devices and Radiological Health, Food and Drug
Administration, Silver Spring, MD.
11:00 am – 11:15 am:
Effect of Silver Nanoparticles on the Differentiation
of Human Mesenchymal Stem Cells
C. Sengstock1, K. Loza2, M. Epple2, T. Schildhauer1,
M. Köller1; 1Surgical Research, Bergmannsheil
University-Hospital, Bochum, GERMANY,
2
Inorganic Chemistry Center for Nanointegration
Duisburg-Essen (CeNIDE), University of DuisburgEssen, Essen, GERMANY.
11:15 am – 11:30 am:
The Effect of Alginate Capsule Composition on
Pancreatic Differentiation of Human Embryonic
Stem Cells
T. Richardson1, P. N. Kumta2, I. Banerjee1;
1
Chemical Engineering, The University of
Pittsburgh, Pittburgh, PA, 2Bioengineering,
The University of Pittsburgh, Pittburgh, PA.
10:15 am – 10:30 am:
Magnetic Targeting for Enhanced Stem Cell
Therapies
R. Harrison, A. El Haj, V. Sottile; School of Medicine, The University of Nottingham, Nottingham,
UNITED KINGDOM, Institute for Science & Technology in Medicine, Keele University, Stoke on Trent,
UNITED KINGDOM.
10:30 am – 10:45 am:
3D Micropatterning of Biological Structures
using Holographic Optical Tweezers
E. R. Britchford, G. R. Kirkham, T. Upton, J. Ware,
G. Gibson, L. D. Buttery, M. Padgett, S. Allen, K.
Shakesheff; School of Pharmacy, The University
of Nottingham, Nottingham, UNITED KINGDOM,
School of Physics and Astronomy, University of
Glasgow, Glasgow, UNITED KINGDOM.
10:45 am – 11:00 am:
Micro-Engineered ECM array as a Platform for
Deciphering Cell-ECM Interaction During Stem
Cell Differentiation
S. Goh, S. Bertera, I. Banerjee; Bioengineering,
University of Pittsburgh, Pittsburgh, PA, Pediatrics, University of Pittsburgh, Pittsburgh, PA.
11:00 am – 11:15 am:
Engineering Tissues with Controllable Synthetic
Circuits
A. E. Anderson, T. L. Deans, J. H. Elisseeff; Cellular
& Molecular Medicine, Johns Hopkins University,
Baltimore, MD, Bioengineering, University of
Utah, Salt Lake City, UT, Biomedical Engineering,
Johns Hopkins University, Baltimore, MD.
11:15 am – 11:30 am:
Primed 3D Injectable Micro-Niches as Cell
Delivery Vehicle and Enabling Low-dosage
Cell Therapy
Y. Li, W. Liu, F. Liu, Y. Zeng, J. Bai, Y. Du; Department of Biomedical Engineering, Tsinghua
University, Beijing, CHINA.
10:45 am – 11:00 am:
Dual Growth Factor Delivery from Bilayered
Hydrogel Composites for Spatially-Guided
Osteochondral Tissue Repair in vivo
S. Lu, J. Lam, J. E. Trachtenberg, E. J. Lee, H.
Seyednejad, J. van den Beucken, Y. Tabata, M.
E. Wong, J. A. Jansen, A. G. Mikos, F. K. Kasper;
Bioengineering, Rice University, Houston, TX,
Biomaterials, Radboud University, Nijmegen,
NETHERLANDS, Biomaterials, Kyoto University,
Kyoto, JAPAN, Surgery, The University of Texas
School of Dentistry at Houston, Houston, TX.
11:00 am – 11:15 am:
Repair of Osteochondral Defect Using Photocrosslinked Gelatin/Hyaluronic Acid Scaffold
H. Lin, K. Shimomura, P. Alexander, R. Tuan;
Orthopaedic Surgery, University of Pittsburgh
School of Medicine, Pittsburgh, PA.
11:15 am – 11:30 am:
An Osteochondral Microphysiological System to
Study the Pathogenesis of Osteoarthritis and
the Effect of Hormonal Exposure
R. Gottardi, H. Lin, T. P. Lozito, P. G. Alexander, K.
L. Clark, E. C. Sefton, T. K. Woodruff, R. S. Tuan;
Department of Orthopaedic Surgery, University
of Pittsburgh, Pittsburgh, PA, Department of
Obstetrics and Gynecology, Northwestern University, Chicago, IL.
10:30 am – 10:45 am:
In Silico 3d Bioprinting: Computer Modeling And
Simulation Of Organ Printing
R. A. Rezende, F. Pereira, K. Brakke, J. Mombach,
V. Kasyanov, V. Mironov, J. Da Silva; Division of 3D
Technologies, Renato Archer Information Technology Center, Campinas, BRAZIL, Mathematics,
Susquehanna University, Selinsgrove, PA,
Federal University of Santa Maria, Renato Archer
Information Technology Center, Santa Maria,
RS, BRAZIL, Laboratory of Biomechanics, Riga
Stradins University and Riga Technical University,
Riga, LATVIA.
10:45 am – 11:00 am:
Determining Force Sensitive Protein-Protein
Interactions in Focal Adhesions
B. Hoffman, A. LaCroix; Biomedical Engineering,
Duke University, Durham, NC.
11:00 am – 11:15 am:
Control Intercellular Interaction With Sound
Waves
F. Guo, P. Li, S. Benkovic, T. Huang; PSU, state
college, PA.
11:15 am – 11:30 am:
Machine Learning Analysis of Multi-Parametric
Single Cell Data Associated with Stem Cell
Differentiation in Nanofiber Scaffolds
D. Chen, S. Sarkar, J. Candia, S. J. Florczyk,
S. Bodhak, C. G. Simon, Jr., J. P. Dunkers, W.
Losert; University of Maryland, College Park,
MD, Biosystems and Biomaterials Division,
National Institute of Standards and Technology,
Gaithersburg, MD.
www.termis.org/am2014
23
CONCURRENT SESSION VIII – DECEMBER 16 (TUE), 1:00 PM – 2:30 PM
GRAND
BALLROOM –
SOUTH SALON
GRAND
BALLROOM –
CENTRAL SALON
GRAND
BALLROOM –
NORTH SALON
CONGRESSIONAL
A
CONGRESSIONAL
B
Imaging and Assessment
(TWIG)
Chairs: Katja Schenke-Layland, Eric Brey,
and Aaron Mohs
Tumor Development
and Cancer
Chairs: Antonios Mikos and Mahendra Rao
Tissue Engineering and
Regenerative Medicine
Strategies
(TWIG)
Chairs: Pamela Yelick and Catherine Kuo
Musculoskeletal Tissue
Regeneration
(TWIG)
Chairs: Tracy Criswell and Johnna Temenoff
Strategies for Respiratory,
Urologic and Gastrointestinal
Tissue Engineering
(TWIG)
Chair: James Yoo
1:00 pm – 1:15 pm:
NGAL as a Prognostic Biomarker for Ischemic
Damage in Machine Warm Perfused Kidneys
A. Meyer, J. Castracane, L. Brasile; SUNY College
of Nanoscale Science and Engineering, Albany,
NY, Nanobioscience, SUNY College of Nanoscale
Science and Engineering, Albany, NY, BREONICS
Inc., Albany, NY.
1:15 pm – 1:30 pm:
Near Infrared Fluorescence Imaging For Visualizing Cartilage Destructive Activities In 3D
Cultured Chondrocytes And In Osteoarthritis
L. Zeng, A. Leahy, S. A. Esfahani, A. Foote, C. Hui,
R. Rainbow, D. Nakamura, B. Tracey, U. Mahmood;
Tufts University, Boston, MA, Massachusetts
General Hospital, Boston, MA.
1:30 pm – 1:45 pm:
Dual-frequency Ultrasound Elastography for
Nondestructive Measurement of Local
Mechanical Properties of Collagen Hydrogels
X. Hong, Y. Hsiao, C. Deng, J. Stegemann;
Biomedical Engineering, University of Michigan,
Ann Arbor, MI.
1:45 pm – 2:00 pm:
Analysis of Non-Enzymatic Collagen Crosslinks
in Engineered Cell-Secreted Extracellular Matrices
D. Mitra, H. Fatakdawala, L. Marcu, J. Leach;
Biomedical Engineering, University of California,
Davis, CA.
2:00 pm – 2:15 pm:
X-ray Phase Contrast Imaging of Encapsulated
Cells and Foreign Body Response
A. A. Appel, V. Ibarra, A. B. Garson, III, H. Guan,
Z. Zhong, M. A. Anastasio, E. C. Opara, E. M. Brey;
Biomedical Engineering, Illinois Institute of
Technology, Chicago, IL, Biomedical Engineering,
Washington University in St. Louis, St. Louis, MO,
National Synchrotron Light Source, Brookhaven
National Laboratory, Upton, NY, Institute for
Regenerative Medicine, Wake Forest School of
Medicine, Winston-Salem, NC.
2:15 pm – 2:30 pm:
Monitoring Of In Vivo Fiber Formation Of Muscle
Precursor Cells Via Magnetization Transfer
(MT)-MRI
M. Rottmar, A. Boss, D. Eberli; Department
of Urology, University Hospital Zurich, Zurich,
SWITZERLAND, Institute for Diagnostic and Interventional Radiology, University Hospital Zurich,
Zurich, SWITZERLAND.
24
1:00 pm – 1:15 pm:
Pre-Cancer Biomarkers Identified From Induced
Regeneration Competent Cells
S. Hernandez, T. Dominko; Biology and Biotechnology, Worcester Polytechnic Institute,
Worcester, MA.
1:00 pm – 1:15 pm:
Strategies To Obtain Hair Follicle-inducing
Dermal Cells
Y. Sung; Kyungpook National University, Daegu,
KOREA, REPUBLIC OF.
1:15 pm – 1:30 pm:
Microfluidic Platform to Examine Tumor
Angiogenesis and Metastasis at High
Spatiotemporal Resolution
V. S. Shirure, S. C. George; Biomedical Engineering, University of California, Irvine, Irvine, CA.
1:15 pm – 1:30 pm:
Pre-vasculature Formation On Human Mesenchymal Stem Cell Sheets
L. ZHANG, Q. XING, Z. QIAN, S. QI, F. ZHAO;
Biomedical Engineering, Michigan Technological
University, HOUGHTON, MI, Department of Burns,
First Affiliated Hospital of Sun Yat-sen University,
GUANGZHOU, CHINA.
1:30 pm – 1:45 pm:
Acellular Liver Scaffolds as a Model to Study
Colon Cancer Metastasis
E. C. Moran, B. Gaston, P. M. Baptista, A. Atala,
S. Soker; Wake Forest Institute for Regenerative
Medicine, Wake Forest University, WinstonSalem, NC, Aragon Health Sciences Institute,
University of Zaragoza, Zaragoza, SPAIN.
1:30 pm – 1:45 pm:
Formation of Extensive Vascular Networks in
Mineralized Tissue In Vitro
B. M. Roux, J. K. Gandhi, E. M. Brey; Biomedical
Engineering, Illinois Institute of Technology,
Chicago, IL.
1:45 pm – 2:00 pm:
Modeling Metastatic Cell Homing and
Colonization Using Biomaterial Mimics of the
Pre-metastatic Niche
B. A. Aguado, S.M. Azarin, S.S. Rao, J.R. Caffe,
G.G. Bushnell, L.D. Shea; Biomedical Engineering,
Northwestern University, Evanston, IL, Chemical
and Biological Engineering, Northwestern
Unviersity, Evanston, IL.
2:00 pm – 2:15 pm:
The Third Dimension: Using the Right Mechanical Model for Mammary Morphogenesis
A. Kurup, T. Tlsty, E. Botvinick; University of
California, Irvine, Irvine, CA, University of
California, San Francisco, San Francisco, CA,
Biomedical Engineering, University of California,
Irvine, Irvine, CA.
2:15 pm – 2:30 pm:
An In Vitro 3-D Liver-Tumor Hybrid Organoid
System for Modeling Metastasis and Drug
Resistance
A. Skardal, M. Devarasetty, C. Rodman, A. Atala,
S. Soker; Institute for Regenerative Medicine,
Wake Forest Baptist Medical Center, WinstonSalem, NC.
TERMIS–AM • 2014
1:45 pm – 2:00 pm:
Treatment of Extremity Injury and Compartment
Syndrome Using Autologous Bone Marrow
Mononuclear Cells in a Large Animal Model
K. W. Gregory, R. Merten, C. Gregory, M. Rutten,
B. Zheng, J. Teach, B. Laraway, A. Rose, R. Sarao,
T. Malarkey, J. Hunt, H. Xie; Center for Regenerative Medicine, OHSU, Portland, OR, Providence St.
Vincent Medical Center, Portland, OR.
2:00 pm – 2:15 pm:
Dual Delivery Biomaterial System for the
Treatment of Growth Plate Injuries
M. S. Riederer, M. Sauque, N. Shaw, N. HadleyMiller, K. A. Payne, M. D. Krebs; Chemical and
Biological Engineering, Colorado School of Mines,
Golden, CO, Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO.
2:15 pm – 2:30 pm:
Recapitulation of Human Hepato-Biliary
Organogenesis in Self-assembled Liver
Organoid Culture
D. Vyas, P. M. Baptista, E. Moran, S. Soker; Wake
Forest Institute for Regenerative Medicine, Winston Salem, NC, Aragon Health Science Institute,
Zaragoza, SPAIN.
1:00 pm – 1:15 pm:
Spatiotemporal Localization of Mesenchymal
Stem Cells via Degradable PEG Hydrogels
Enhances Bone Allograft Healing
M. Hoffman, D. Benoit; Department of Biomedical Engineering and Center for Musculoskeletal
Research, University of Rochester, Rochester, NY,
Department of Biomedical Engineering, Chemical
Engineering, and Center for Musculoskeletal
Research, University of Rochester, Rochester, NY.
1:15 pm – 1:30 pm:
In Vivo Bone Regeneration by Acellular or
MSC-Encapsulating Pre-Mineralized CollagenChitosan Hydrogel Microbeads in a Critical-Sized
Segmental Femoral Defect Model
J. K. Wise, E. L. Daley, A. I. Alford, S. A. Goldstein,
J. P. Stegemann; Biomedical Engineering, University of Michigan, Ann Arbor, MI, Orthopaedic
Surgery, University of Michigan, Ann Arbor, MI.
1:30 pm – 1:45 pm:
Demineralized Bone Matrix Fiber Scaffolds for
Bone Regeneration
M. Francis, R. Rodriguez, E. Breathwaite, N.
Kemper, S. Chen; LifeNet Health Institute of
Regenerative Medicine, Virginia Beach, VA.
1:45 pm – 2:00 pm:
Growth Factor Loaded Keratin Hydrogels for
Treatment of VML in a Rat Model
J. A. Passipieri, H. Baker, M. Siriwardane, C.
Okoukoni, C. E. Stewart, M. Ellenburg, S. Tomblyn,
L. Burnett, G. Christ; Wake Forest Institute for
Regenerative Medicine, Wake Forest University,
Winston-Salem, NC, University of Virginia, Charlottesville, VA, KeraNetics, Winston-Salem, NC.
2:00 pm – 2:15 pm:
Combined Delivery of Small RNAs for In Situ
Muscle Regeneration
N. Kim, S. Kim, J. J. Yoo, A. Atala, S. Lee; Wake
Forest Institute for Regenerative Medicine, Wake
Forest School of Medicine, Winston-Salem, NC.
2:15 pm – 2:30 pm:
Anti-oxidant Therapy For Skeletal Muscle
Regeneration After Compression Injury In Rats
B. Yoseph, Y. Zhou, M. Bethea, S. Socker, T.
Criswell; Surgery, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, WFIRM,
Wake Forest Institute for Regenerative Medicine,
Winston-Salem, NC.
1:00 pm – 1:30 pm:
Invited Speaker: Khalil N. Bitar
Neuromuscular Disorders of the Gut:
Regenerative Medicine Approaches Lessons
Learned & Future Vision
1:30 pm – 1:45 pm:
Recellularization Strategies for Whole-Organ
Kidney Scaffolds: An Evaluation of Ureteral and
Arterial Seeding
J. S. Uzarski, B. M. Bijonowski, H. Ward, A.
Wandinger-Ness, W. M. Miller, J. A. Wertheim;
Comprehensive Transplant Center, Northwestern
University, Chicago, IL, Department of Medicine,
University of New Mexico, Albuquerque, NM,
Department of Pathology, University of New
Mexico, Albuquerque, NM, Chemical and Biological Engineering, Northwestern University,
Evanston, IL.
1:45 pm – 2:00 pm:
Biomechanical Properties and Effect on
Tracheobronchial Growth of 3-D Printed
Bioresorbable Airway Splints for Treating
Tracheobronchomalacia
R. J. Morrison, H. B. Nasser, D. A. Zopf, C. L.
Flanagan, M. Wheeler, G. E. Green, S. J. Hollister;
Department of Otolaryngology-Head & Neck
Surgery, University of Michigan, Ann Arbor, MI,
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, Department of
Animal Sciences, University of Illinois, UrbanaChampaign, IL.
2:00 pm – 2:15 pm:
Ovarian Follicles Develop and Ovulate within a
Bioengineered Artificial Ovary
M. M. Laronda, A. L. Rutz, A. E. Jakus, S. Xiao,
K. A. Whelan, J. A. Wertheim, R. N. Shah, T. K.
Woodruff; Division of Reproductive Science,
Department of Obstetrics & Gynecology, Feinberg
School of Medicine, Northwestern University,
Chicago, IL, Institute for BioNanotechnology in
Medicine, Northwestern University, Chicago,
IL, Comprehensive Transplant Center, Feinberg
School of Medicine, Northwestern University,
Chicago, IL.
2:15 pm – 2:30 pm:
Safety of Skeletal Muscle Precursor Cell Therapy
in a Dog Model of Urethral Sphincter Deficiency
J. Williams, D. Eckman, A. Dean, J. Allikson, J.
Cline, j. Yoo, A. Atala; Regenerative Medicine,
Wake Forest University, Winston-Salem, NC,
Biomedical Sciences, Midwestern University,
Glendale, AZ, Pathology/Section on Comparative
Medicine, Wake Forest University, WinstonSalem, NC.
FINAL PROGRAM
SPONSORS
GOLD LEVEL
SILVER LEVEL
BRONZE LEVEL
ADDITIONAL SPONSORS
Sponsor of the TERMIS-AM Industry Committee
One-Day Event
Sponsor of the Commercialization & Regulation TWIG
Business Plan Competition
Bag Inserts
Sponsor of the TERMIS-AM Opening Symposium
Keynote Address
Media Sponsor
Mary Ann Liebert, Inc., publisher of
Tissue Engineering, Part A, B, and C
www.termis.org/am2014
25
EXHIBITOR FLOOR PLAN
26
TERMIS–AM • 2014
FINAL PROGRAM
EXHIBITORS
AABB Center for Cellular
Therapies
Booth #31
T: 301-215-6513
W: http://www.aabb.org/
Evonik Corporation
Booth #16
T: 732-981-5269
W: www.evonik.com/
ACS Publications
Booth #9
T: 202-872-6862
W: http://pubs.acs.org/
FMC BioPolymer/NovaMatrix
Booth #19
T: +47-67815525
W: www.novamatrix.biz/
Home/FMCBioPolymer.aspx
BioBots Inc.
Booth #
T: 305-742-3311
Instron
Booth #2
T: 781-757-5690
W: www.instron.com/
BioSpherix, Ltd.
Booth #29
T: 315-387-3414
W: http://www.apexbiomed.
com/
International Institute
for the Advancement of
Medicine (IIAM)
Booth #15
T: 845-694-8440
W: www.iiam.org/
Bose Corporation ElectroForce Systems Group
Booth #11
T: 952-278-3070
W: www.bose-electroforce.com/
CellScale Biomaterials
Testing
Booth #35
T: 226-868-5333
W: cellscale.com/
IOP Publishing
Booth #30
T: 44117-9297481
W: ioppublishing.org/
KANEKA Corporation
Booth #26
T: 81-50-3133-7668
W: www.kaneka.com/
www.termis.org/am2014
27
EXHIBITORS
beMatrix
Low Endotoxin Gelan
28
TERMIS–AM • 2014
TM
Lifecore Biomedical
Booth #13
T: 952-368-6321
W: www.lifecore.com/
PreSens Precision Sensing
GmbH
Booth #14
T: +1-941-942-72132
W: www.presens.de/
LifeForm Healing Research
Booth #10
T: 940-206-6064
W: lifeformhealingresearch.com/
RoosterBio Inc.
Booth #6
T:301-360-3545
W: www.roosterbio.com/
MATE (Mechano-Active
Tissue Engineering)
Booth #23
T: 202-872-6862
STEMCELL Technologies,
Inc.
Booth #21
T:604-675-7763
W: www.stemcell.com/
McGowan Institute for Regenerative Medicine (part of
the University of Pittsburgh)
Booth #17
T: 412-624-5293
W: www.mirm.pitt.edu/
SynGen, Inc.
Booth #18
T: 916-706-0923
W: syngeninc.com/
NITTA Gelatin NA, Inc.
Booth #27
T: 919-238-3311
W: nitta-gelatin.com/
Tissue Source, LLC
Booth #7
T: 888-984-7783
W: www.tissue-source.com/
Optics 11
Booth #25
T: +31 20-5987917
W: optics11.com/
Wake Forest Institute for
Regenerative Medicine
Booth #22
T: 336-713-7293
W: http://www.wakehealth.
edu/WFIRM/
POSTER PRESENTATIONS
POSTER PRESENTATIONS
306
POSTER SESSION I –
DECEMBER 14TH (SUN), 4:30 PM – 6:30 PM
POSTER SESSION II –
DECEMBER 15TH (MON), 4:30 PM – 6:30 PM
EXHIBIT HALL - RENAISSANCE WEST
AND EAST
300
301
302
303
304
Current State of the hiPS Cell Culture Apparatus
and the Culture Cost
H. Kitajima, M. Kino-oka; Graduate school of
Engineering, Osaka University, Osaka, JAPAN.
An In Silico Perfusion Bioreactor For Maturation Of
3
d Bioprinted Organs
R. A. Rezende1, J. Nogueira1, V. Lara1, D. Kemmoku1, R.
Maciel Filho2, V. Mironov1, J. Da Silva1; 1Division of 3D
Technologies, Renato Archer Information Technology
Center, Campinas, BRAZIL, 2University of Campinas,
Campinas, BRAZIL.
Development of A Novel Modular System for
Preparing Regenerative Medicine Products
M. Mizutani1, H. Kubo2, M. Wada3, K. Tanimoto4, T.
Shimizu5, M. Kino-Oka6; 1Osaka University, Suita-shi,
Osaka, JAPAN, 2Nihon Koden Corporation, Shinjukuku, Tokyo, JAPAN, 3ABLE Corporation, Shinjuku-ku,
Tokyo, JAPAN, 4Shibuya Kogyo Co., LTD., Kanazawashi, Ishikawa, JAPAN, 5Institute of Advanced
Biomedical Engineering and Science, Tokyo Women’s
Medical University, Shinjuku-ku, Tokyo, JAPAN,
6
Graduate School of Engineering, Osaka University,
Suita-shi, Osaka, JAPAN.
Highly Organized Three-Dimensional Tissue
Construct Created in a Rotating Wall Vessel
Bioreactor
Q. Xing, Z. Qian, K. Yates, F. Zhao; Biomedical
Engineering, Michigan Technological University,
Houghton, MI.
D Printed Scaffolds With Controlled Release of
Dexamethasone for Bone Regeneration
P. Costa1, A. Puga2, A. Concheiro3, D. Busch1, M.
van Griensven2, C. Alvarez-Lorenzo3; 1Institute for
Medical Microbiology, Immunology and Hygiene,
Technical University Munich, Munich, GERMANY,
2
Department of Experimental Trauma Surgery,
Klinikum Rechts der Isar, Technical University Munich,
Munich, GERMANY, 3Departamento de Farmacia y
Tecnología Farmacéutica, Universidad de Santiago
de Compostela, Santiago de Compostela, SPAIN.
307
308
309
310
311
3
312
313
Effect Of Flow Conditions In A 3d Tumor Model
Generated Using A Flow Perfusion Bioreactor
M. Santoro1, S. Lamhamedi-Cherradi2, B. A.
Menegaz2, J. A. Ludwig2, A. G. Mikos1; 1Chemical and
Biomolecular Engineering, Rice University, Houston,
TX, 2Sarcoma Medical Oncology, The University of
Texas MD Anderson Cancer Center, Houston, TX.
Modeling Liver Metabolism
C. German, S. Madihally; Chemical Engineering,
Oklahoma State University, Stillwater, OK.
Growth Factor Controlled Osteogenic
Differentiation of Mesenchymal Stem Cells in
Dynamic Bioreactor System
B. B. Nguyen, H. Ko, J. P. Fisher; Fischell Department
of Bioengineering, University of Maryland, College
Park, MD.
Site-specific Material Properties And The Additive
Manufacturing Of Nitinol Musculoskeletal Implants
M. Elahinia1, N. Shayesteh Moghaddam1, M. Taheri
Andani1, R. Rahmanian1, J. Walker1, M. J. Miller2, D.
Dean2; 1The University of Toledo, Toledo, OH, 2The
Ohio State University, Columbus, OH.
Tuning the Material Properties of 3D Printed
Regenerative Bone Implants
D. Dean1, E. Mott1, M. O. Wang2, N. Shayesteh
Moghaddam3, M. Taheri Andani3, J. P. Fisher4, M.
Elahinia3, M. J. Miller1; 1Plastic Surgery, The Ohio State
University, Columbus, OH, 2Fischell Department of
Bioengineering, University of Maryland, College
Park, MD, 3Mechanical, Industrial and Manufacturing
Engineering, University of Toledo, Toledo, OH,
4
Department of Bioengineering, University of
Maryland, College Park, MD.
Growth Factor Stimulation Improves the Structure
and Properties of Scaffold-Free Engineered
Auricular Cartilage Constructs
R. Rosa1, P. Joazeiro1, J. Bianco1, M. Kunz2, J. Weber3,
S. Waldman4; 1Department of Histology and
Embryology, University of Campinas, Campinas,
BRAZIL, 2School of Computing, Queen’s University,
Kingston, ON, CANADA, 3Queen’s University,
Kingston, ON, CANADA, 4Chemical Engineering,
Ryerson University, Toronto, ON, CANADA.
Pretreatment Of Electromagnetic Field To 3d
Printed Chondrocytes For The Enhancement Of
Cartilage Regeneration
H. Yi, M. Park, K. Kang, J. Hong, J. Jang, D. Cho;
POSTECH, Pohang, KOREA, REPUBLIC OF.
A Novel In Vivo Bioreactor Enables A Controlled
Environment For Regenerative Surgery
S. W. Jordan, C. Chavez-Munoz, S. J. Hong, T. A.
Mustoe, R. D. Galiano; Plastic Surgery, Northwestern
University, Chicago, IL.
www.termis.org/am2014
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315
316
318
319
320
321
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An In Vitro and Histological Approach to Evaluate
the Functionality and Apoptotic Index of Vascular
Graft Matrices
A. Linthurst Jones1, A. Miller1, Z. Chen2, E. Greene2, L.
Campbell2, K. Brockbank2; 1Research & Development,
LifeNet Health, Virginia Beach, VA, 2Cell & Tissue
Systems, Charleston, SC.
Characterization and Functional Analysis of
Endothelial Cells Derived From Human Embryonic
Stem Cells
X. Lu1, S. I. Vernardis1, P. I. Lelkes2, P. M. Polak1, A.
Mantalaris1; 1Chemical Engineering, Imperial College
London, London, UNITED KINGDOM, 2Temple
Institute for Regenerative Medicine and Engineering,
Temple University, Philadelphia, PA.
D Printed Blood Vessels
A. D. Cook, C. Dodge, D. Day, J. Griggs; Brigham
Young University, Provo, UT.
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323
3
Severe Intimal Hyperplasia Formation in Heparin
Modified Crosslinked Decellularized Arteries in a
Rat Model
B. Jiang1, B. Akgun2, L. Perrin1, R. Lam3, G. Ameer1,
J. Wertheim2; 1Biomedical Engineering Department,
Northwestern University, Evanston, IL, 2Department
of Surgery, Northwestern University, Chicago, IL,
3
Northwestern University, Evanston, IL.
Directing Vascularization Using Modular
Microtissues
A. Rioja, A. Putnam, J. Stegemann; Biomedical
Engineering, University of Michigan, Ann Arbor, MI.
Differentiation of Perivascular Progenitor Cells from
Human Aortic Adventitia
B. W. Ellis1, B. R. Green2, J. C. Hill3, V. S. Donnenberg3,
T. G. Gleason3, J. A. Phillippi3; 1Bioengineering,
University of Pittsburgh, Pittsburgh, PA,
2
Cardiothoracic Surgery, University of Pittsburgh
Medical Center, Pittsburgh, PA, 3Cardiothoracic
Surgery, University of Pittsburgh, Pittsburgh, PA.
Use Of Human Embryonic Stem Cell-derived
Cardiomyocytes For In Vitro Cardiotoxicity
Screening
N. G. Posnack1, H. Ding1, R. Jaimes, III2, M. Laflamme3,
N. Sarvazyan1; 1Pharmacology & Physiology,
George Washington University, Washington, DC,
2
Biomedical Engineering, George Washington
University, Washington, DC, 3Pathology, University of
Washington, Seattle, WA.
TERMIS–AM • 2014
324
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Tissue-Engineered Vascular Grafts by Combining
Cell Sheet and Electrospun Scaffold
H. Ahn1, Y. Ju1, H. Takahashi2, T. Okano3, J. J. Yoo1, A.
Atala1, S. Lee1; 1Wake Forest Institute for Regenerative
Medicine, Wake Forest School of Medicine, WinstonSalem, NC, 2Institute of Advanced Biomedical
Engineering and Science, Tokyo Women’s Medical
University, Tokyo, JAPAN, 3Institute of Advanced
Biomedical Engineering and Science, Tokyo Women’s
Medical University, Winston-Salem, NC.
Impact of Hormone Presentation on the
Recapitulation of Endometrial Angiogenesis within
a Collagen GAG Scaffold
J. C. Pence1, B. A. Harley1, K. B. Clancy2; 1Chemical
and Biomolecular Engineering, University of Illinois,
Urbana, IL, 2Anthropology, University of Illinois,
Urbana, IL.
Tuning Composition and Architecture of Biomimetic
Scaffolds for Enhanced Matrix Synthesis by Murine
Cardiomyocytes
C. R. Kothapalli, A. Gishto, K. Farrell; Chemical &
Biomedical Engineering, Cleveland State University,
Cleveland, OH.
Nitric Oxide Stimulates Matrix Synthesis and
Deposition by Adult Human Smooth Muscle Cells
within Biomimetic Cocultures
C. R. Kothapalli, P. Simmers, A. Gishto; Chemical &
Biomedical Engineering, Cleveland State University,
Cleveland, OH.
Engineered Heart Tissue to Aid Venous Flow
L. Swift, V. Karimi, M. Velez, H. Simonyan, N. Patev,
N. G. Posnack, N. Sarvazyan; Pharmacology and
Physiology, The George Washington University,
Washington, DC.
Combined Endothelial Sprouting and Tubulogenesis
in 3D Fibrin Gel
S. Riemenschneider, R. Tranquillo; Chemical
Engineering and Materials Science, University of
Minnesota, Minneapolis, MN.
Network Formation By Human Amniotic Fluidderived Stem Cells Within Fibrin/poly(ethylene
Glycol) Hydrogels
O. Benavides1, A. R. Brooks1, J. P. Quinn1, R. Ruano2, J.
Jacot1; 1Bioengineering, Rice University, Houston, TX,
2
Obstetrics & Gynecology, Texas Children’s Hospital,
Houston, TX.
Tri-Culture System for Engineering Highly
Vascularized Myocardial Tissue Grafts
J. Morrissette McAlmon, D. Hutton, W. Grayson;
Biomedical Engineering, Johns Hopkins University,
BALTIMORE, MD.
POSTER PRESENTATIONS
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337
338
339
340
341
342
Cardiac Tissue Engineering To Treat Lymphedema:
Aiding Lymph Drainage By Creating A Biological
Mini Pump Outside The Heart
N. Muselimyan1, L. Swift1, D. Brooks1, M. Laflamme2,
N. Sarvazyan1; 1Pharmacology and Physiology, The
George Washington University, Washington, DC,
2
Pathology, The George Washington University,
Washington, DC.
Immunoengineering MHC-I Depleted hESC As A
Source Of Host-Compatible Cardiomyocytes
Z. Karabekian1, H. Ding1, I. Ivanova1, G. Stybayeva2,
N. Sarvazyan1; 1Pharmacology and Physiology, The
George Washington University, Washington, DC,
2
Biomedical Engineering, UC Davis, Davis, CA.
343
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A Hybrid Biomaterial for Drug Delivery in
Cardiovascular Implants
L. Bracaglia, M. Messina, J. P. Fisher; University of
Maryland, College Park, MD.
Promoting Neonatal Cardiomyocyte Proliferation
Using a Cryptic Peptide Derived from Fibrillin-1
K. J. Edmunds, C. Williams, L. D. Black, III;
Department of Biomedical Engineering, Tufts
University, Medford, MA.
Microfluidic Control of Mesenchymal Stem Cell Fate
for Spatial Engineering of Osteochondral Units
S. Goldman1, G. Barabino2; 1Georgia Institute of
Technology, Atlanta, GA, 2City College of New York,
New York, NY.
Age and Gender Dependent Differences in Skeletal
Muscle Regeneration after Compression Injury in
Rats
Y. Zhou, D. Lovell, M. Bethea, S. Soker, T. Criswell;
Regenerative Medicine, Wake Forest University,
Winston-Salem, NC.
Enhanced Human Bone Marrow Mesenchymal Stem
Cell Function on 3D Printed Nano Bone Scaffolds
with Microvascular Network
B. B. Holmes1, L. G. Zhang2; 1MAE, The George
Washington University, Burke, VA, 2MAE, The George
Washington University, Washington, DC.
The Effect of Fibronectin, FGF, IGF, and TGFβ on
Proliferation and Migration of Human Mesenchymal
Stem Cells
T. Rami, D. Suresh, R. Dodia, B. Kim, K. Chiniaeff, M.
McCoy, B. Tawil; California State University, Channel
Islands, Camarillo, CA.
The Influence of Fibronectin, bFGF, and VEGF on
Human Foreskin Fibroblast Cells
Z. Amin, A. Flores, P. Garimidi, M. Martinez, K. Nhan;
Biotechnology and Bioinformatics, California State
University Channel Islands, Camarillo, CA.
346
347
348
349
350
Tissue Engineering for the Repair of Ischemically
Damaged Kidneys
L. Brasile1, B. Stubenitsky2; 1BREONICS Inc., Albany,
NY, 2Plastic Reconstructive Surgery, Utrecht
University, Utrecht, NETHERLANDS.
Altering the Mechanical Environment of Cellularized
Polyurethane-Collagen Composite Meshes for
Connective Tissue Applications
P. Thayer1, E. Tong1, L. Dahlgren1, S. Guelcher2, A.
Goldstein1; 1Virginia Tech, Blacksburg, VA, 2Vanderbilt
University, Nashville, TN.
Increase of Type 2 collagen Accumulation in
Shrinkage-free Scaffold-free Cartilage-like MSCs
Sheet
Y. Sato1, S. Wakitani2, M. Takagi1; 1Graduate School of
Engineering, Hokkaido University, Sapporo, JAPAN,
2
Graduate School of Biomedical Sceineces, Hiroshima
University, Hiroshima, JAPAN.
The Effect of Using Vitrified Chondrocyte Sheets on
Articular Cartilage Repair
Y. Tani1, M. Sato1, H. Nagashima2, M. Maehara2, M.
Yokoyama1, M. Kobayashi1, E. Toyoda1, T. Kawake1, E.
Okada1, J. Mochida1; 1Orthopaedic Surgery, Surgical
Science, Tokai University, School of Medicine, Isehara,
JAPAN, 2Laboratory of Developmental Engineering,
School of Agriculture, Meiji University, Kawasaki,
JAPAN.
Surgical Implantation of a Bioengineered Human
Smooth Muscle Tubular Hollow Organ
E. Zakhem1, M. Elbahrawy2, K. N. Bitar1; 1Molecular
Medicine and Translational Sciences, Wake Forest
Institute for Regenerative Medicine, Winston
Salem, NC, 2Wake Forest Institute for Regenerative
Medicine, Winston Salem, NC.
Age-Dependent Differences in Skeletal Muscle
Regeneration in Response to Cell Therapy After
Injury
Y. Zhou, D. Lovell, M. Bethea, S. Soker, T. Criswell;
Regenerative Medicine, Wake Forest University,
Winston-Salem, NC.
Designing an Elastic Scaffold with Shape-Memory
for Functional Tissue Delivery
M. Montgomery, B. Zhang, L. Reis, M. Radisic;
University of Toronto, Toronto, ON, CANADA.
Tissue Engineering the Vasculature of an Allograft
into a Functional Autograft
L. Brasile1, B. Stubenitsky2; 1BREONICS Inc., Albany,
NY, 2Plastic Reconstructive Surgery, Utrecht
University, Utrecht, NETHERLANDS.
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Enriched Intestinal Stem Cell Seeding Improves the
Architecture of Tissue Engineered Intestine
Y. Liu1, T. Rager1, J. Lannutti2, J. Johnson3, P.
Painter1, T. Nelson2, J. Enmark3, G. Besner1; 1Center
for Perinatal Research, The Research Institute at
Nationwide Children’s Hospital, Columbus, OH,
2
Department of Materials Science and Engineering,
The Ohio State University, Columbus, OH, 3Nanofiber
Solutions, LLC, Columbus, OH.
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Multi-Agent model of Vascularized Bone Tissue
Growth within Porous Biomaterials
E. Bayrak1, H. Mehdizadeh1, B. Akar2, S. Somo2,
E. Brey2, A. Cinar1; 1Chemical and Biological
Engineering, Illinois Institute of Technology, chicago,
IL, 2Biomedical Engineering, Illinois Institute of
Technology, chicago, IL.
Computational Simulations of the Tissue Spheroids
Fusion Process on Bioprinting
R. Rezende1, K. Brakke2, V. Lara1, J. Nogueira1, F.
Pereira1, D. Kemmoku1, V. Mironov1, J. Da Silva1;
1
Division of 3D Technologies, Renato Archer
Information Technology Center, Campinas, BRAZIL,
2
Mathematics, Susquehanna University, Selinsgrove, PA.
Kinetic Model for Expansion Culture of iPS Cells by
Considering the Deviation from Undifferentiated
State on Feeder Layers
S. Fusa, T. X. Ngo, M. Kino-oka; Biotechnology, Osaka
University, Osaka, JAPAN.
The Effect of Low Level Laser, Low Intensity Pulsed
Ultrasound and the Combination of them on
osteogenesis in vitro
A. Husein1, M. Jawad1, A. Azlina1, M. Alam1, R.
Hassan1, R. Shaari2; 1School of Dental Sciences, USM
University, Kubang Kerian, Kelantan, MALAYSIA,
2
ClinicalVeterinary Medicine, Faculty of Veterinary
Medicine, UMK University, Kota Bharu, Kelantan,
MALAYSIA.
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Mechanistic Insights into Early Endoderm
Differentiation of Human Embryonic Stem
Cells using Systems Level Analysis of Signaling
Interactions
S. Mathew, S. Sundararaj, H. Mamiya, I. Banerjee;
Chemical and Petroleum Engineering, University of
Pittsburgh, Pitsburgh, PA.
Electrochemical Impedance Immunosensors for
Detection of Salivary Gland Secretory Products for
Tissue Engineering
R. A. Schramm, III1, J. Castracane1, M. Larsen2, D.
Nelson2, S. Sequiera2, K. Jayarathanam1, L. Sfakis1;
1
CNSE, Albany, NY, 2Department of Biological
Sciences, University at Albany, Albany, NY.
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The Fate and Contribution of HMS0014 Cells cultured
on Cellmatrix Type I-A Scaffold
S. Kumabe, M. Nakatsuka, A. Morishita, K. Ueda,
Y. Iwai; Department of Oral Anatomy, Osaka Dental
University, Hirakata-shi, JAPAN.
Non Invasive Techniques of Low level Laser and
Low Intensity Pulsed Ultrasound Therapy Effects
on Bone Remodelling during Orthodontic Tooth
Movement
M. Jawad1, A. Husein2, M. Alam1, R. Hassan1, A. Azlina3,
R. Shaari4; 1Orthodontics, School of Dental Sciences,
USM University, Kubang Kerian, Kelantan, MALAYSIA,
2
Prosthodontics, School of Dental Sciences, USM
University, Kubang Kerian, Kelantan, MALAYSIA,
3
Molecular Biology, School of Dental Sciences, USM
University, Kubang Kerian, Kelantan, MALAYSIA,
4
ClinicalVeterinary Medicine, Faculty of Veterinary
Medicine, UMK University, Kubang Kerian, Kelantan,
MALAYSIA.
The Effect of Titanium with Heparin/BMP-2 Complex
for Improving Osteoblast Activity
J. Lee, Y. Yun, S. Kim, H. Song; Korea University,
Seoul, KOREA, REPUBLIC OF.
3
-D Micropatterned Poly(ε-caprolactone) Scaffolds
for Guided Periodontal Ligament Cell Alignment
S. P. Pilipchuk, E. Heffez, J. V. Sugai, C. L. Flanagan,
S. J. Hollister, W. V. Giannobile; University of
Michigan, Ann Arbor, MI.
An in vitro study of Hard Tissue Formation around
Implants with Culture of HMS0014 Cells in Cellmatrix
Type I-A Collagen Gel 3D Scaffold
Y. Iwai, A. Morishita, M. Nakatsuka, K. Ueno, S.
Kumabe; Department of Oral Anatomy, Osaka Dental
University, Hirakata-shi, JAPAN.
Bone Tissue Engineering For Cleft Lip And Palate
Patients Using Non Invasive Sources Of Stem Cells
D. F. Bueno1, D. Tanikawa2, D. L. Rocha2, C. Pinheiro3,
M. A. Andrade4, L. L. Reis5; 1Stem Cell and Tissue
Engineering, Sirio Libanes Hospital / Menino Jesus
Hospital, Sao Paulo, BRAZIL, 2Plastic Surgery, Sirio
Libanes Hospital / Menino Jesus Hospital, Sao Paulo,
BRAZIL, 3Instituto de Ensino e Pesquisa (IEP), Sírio
Libanês Hospital, Sao Paulo, BRAZIL, 4Stem Cell
and Tissue Engineering, Menino Jesus Hospital, Sao
Paulo, BRAZIL, 5Instituto de Ensino e Pesquisa (IEP),
Sirio Libanes Hospital, Sao Paulo, BRAZIL.
NIDCR Research Training and Career Development
Opportunities
L. Frieden, L. Mertens King; National Institute of
Dental and Craniofacial Research, Bethesda, MD.
POSTER PRESENTATIONS
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Segmental Mandibular Defects in Sinclair Miniature
Pigs Mimic Human Mandibular Reconstruction Cases
D. Silliman, P. Carlisle, D. Owens, D. Tucker, R. Hale, P.
BrownBaer; United States Army Institute of Surgical
Research, JBSA Fort Sam Houston, TX.
Sequential Delivery of BMP-2 And BMP-7 using a
Heparinized Collagen Membrane for In vivo Bone
Regeneration
J. Huh; Department of Prosthodontics, Dental
Research Institute, Yangsan, KOREA, REPUBLIC OF.
Synthetic 43-Amino Acid Amelogenin Peptide is
Osteogenic and Osteoinductive
R. Olivares-Navarrete1, S. L. Hyzy1, K. Vesper2, K. A.
Lawrence3, C. Appert4, Z. Schwartz1, B. D. Boyan1;
1
Biomedical Engineering, Virginia Commonwealth
University, Richmond, VA, 2Georgia Regents
University, Augusta, GA, 3Georgia Institute of
Technology, Atlanta, GA, 4Institut Straumann, Basel,
SWITZERLAND.
Comparison in Drug Release Behaviors of
Monodisperse PLGA Microspheres with Different
Sizes
J. WU, K. Yeung, M. To; The University of Hong Kong,
Hong Kong, HONG KONG.
Preparation And Release Evaluation Of
Biodegradable Mpeg-pcla Film For Drug Carrier
Having Elasticity.
J. Park, Jr., D. Kwon, B. Lee, G. Lee, J. Kim, M. Kim;
molecular science, Ajou university, suwon, KOREA,
REPUBLIC OF.
Preparation Of Fibrillized Collagen Microsphere
And Evaluation Of Physical And Biological
Properties
A. Matsuhashi, K. Nam, T. Kimura, A. Kishida; Institute
of Biomaterials and Bioengineering, Tokyo Medical
and Dental University, Tokyo, JAPAN.
Colloidal-Phase Mediated Heteroaggregation for
Controlled Fabrication of Functional, StimuliResponsive Microparticles
S. Saxena1, D. D. Sullivan2, T. C. McDevitt2, L. Lyon3;
1
Materials Science and Engineering, Georgia Institute
of Technology, Atlanta, GA, 2Wallace H. Coulter
Department of Biomedical Engineering, Georgia
Institute of Technology, Atlanta, GA, 3School of
Chemistry and Biochemistry, Georgia Institute of
Technology, Atlanta, GA.
Compare The Efficiency Of Gene Delivery And
Toxicity To Mesenchymal Stem Cells Using Synthetic
Polymer Carriers
J. Kwon, S. Park, J. Baek, H. Lee, M. Kim; Department
of Molecular Science and Technology, Ajou
University, Suwon, KOREA, REPUBLIC OF.
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Development of Antioxidant Chitosan/Fucoidan
Nanoparticles for Gentamicin Delivery
Y. Huang, R. Li; Food Science, Life Science, Keelung,
TAIWAN.
Local Induction of Browning in White Adipose
Tissue Using a PLGA Delivery System
J. Yang, A. Anderson, J. Elisseeff; Biomedical
Engineering, Johns Hopkins University, Baltimore, MD.
Microneedle Array-Mediated Intradermal Delivery
of Tumor Necrosis Factor-Alpha-Inhibitors
E. Korkmaz1, E. E. Friedrich2, G. Erdos3, A. Mathers3,
L. D. Falo, Jr.3, B. Ozdoganlar1, N. R. Washburn2;
1
Department of Mechanical Engineering, Carnegie
Mellon University, Pittsburgh, PA, 2Department of
Biomedical Engineering, Carnegie Mellon University,
Pittsburgh, PA, 3Department of Dermatology,
University of Pittsburgh School of Medicine,
Pittsburgh, PA.
Multifunctional Magnetic Nanoparticles for
Localized Elastic Matrix Regenerative Repair in
Abdominal Aortic Aneurysms (AAAs)
B. Sivaraman, L. Moore, M. Zborowski, A.
Ramamurthi; Biomedical Engineering, Cleveland
Clinic Foundation, Cleveland, OH.
Peptide-Functionalized Polymers Localize to
Resorption Pits for Bone-Targeted Drug Delivery
M. R. Newman1, C. S. Schmitt2, T. J. Sheu3, J. E.
Puzas3, D. S. W. Benoit1; 1Biomedical Engineering,
University of Rochester, Rochester, NY, 2Chemical
Engineering, University of Rochester, Rochester, NY,
3
Center for Musculoskeletal Research, University of
Rochester Medical Center, Rochester, NY.
Protein Stabilized And Sustained Deliverable
Nanofiber Smart Scaffold For Multiphase Tissue
Regeneration
J. Giri1, B. Chandra2, N. Kumar2, M. Cicerone3; 1Indian
Institute of Technology, Hyderabad, INDIA, 2American
Dental Association Foundation, Gaithersburg, MD,
3
National Institute of Standards and Technology,
Gaithersburg, MD.
Synthesis and Characterization of a Simvastatin
Polyprodrug for Potential Tissue Regeneration
Applications
T. A. Asafo-Adjei1, T. D. Dziubla2, D. A. Puleo1;
1
Department of Biomedical Engineering, University
of Kentucky, Lexington, KY, 2Department of Chemical
and Materials Engineering, University of Kentucky,
Lexington, KY.
Engineering Exosomes for DNA Delivery Towards
Regenerative Gene Therapy
T. N. Lamichhane, R. S. Raiker, S. M. Jay; Fischell
Department of Bioengineering, University of
Maryland, College Park, MD.
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Engineering Poly(beta-amino ester) End-Group and
PEGylation to Improve Nanoparticle Stability and
Cellular Uptake
J. Kim, J. C. Sunshine, J. J. Green; Biomedical
Engineering, Johns Hopkins University School of
Medicine, Baltimore, MD.
Environmentally Triggered Nanoparticles For
Efficient And Cancer-specific siRNA Delivery To
Primary Human Glioblastoma
K. L. Kozielski, B. H. Kim, S. Y. Tzeng, B. A. Hurtado
de Mendoza, J. J. Green; Biomedical Engineering,
Johns Hopkins University, Baltimore, MD.
Unique Stromal Cell Derived Factor-1 (SDF-1)
Infused Hydrogel Carriers for Healing of Volumetric
Bone Defects
B. George1, C. Crowe1, H. Pham1, S. Farnebo1, R.
Carrera2, J. Chang1, A. B. Castillo1; 1Stanford University
School of Medicine, Palo Alto, CA, 2Stanford
University, Palo Alto, CA.
Cardiokit: A System For Cardiac Tissue Engineering
And Toxicity Assessment
P. J. Gouveia1, S. Rosa1, L. Ricotti2, R. N. Carvalho1,
A. Menciassi3, L. Ferreira1; 1Biomaterials and Stem
Cell-Based Therapeutic research group, Centro
de Neurociências e Biologia Celular, Coimbra,
PORTUGAL, 2Micro-Nano-Bio Systems and Targeted
Therapies, Biorobotics Institute Polo Sant’ Anna
Valdera, Scuola Superiore Sant’ Anna, Pontedera,
ITALY, 3Surgical Robotics & Allied Technologies
group, Biorobotics Institute Polo Sant’ Anna Valdera,
Scuola Superiore Sant’ Anna, Pisa, ITALY.
The Influence Of Substrate Stiffness On Adipose
Expansion And Function
M. Vaicik1, R. Cohen2, J. Rios1, G. Papavasiliou1, E. M.
Brey1; 1Illinois Institute of Technology, Chicago, IL,
2
Medicine, University of Chicago, Chicago, IL.
Isolation, Characterization, and Functional Analysis
of Human Salivary Gland Myoepithelial Cells for use
in Tissue Regeneration
D. R. Zakheim1, P. Chapela2, K. S. Cannon1, R. L.
Duncan1, M. C. Farach-Carson2, D. A. Harrington2,
X. Jia3, R. L. Witt4, S. Pradhan-Bhatt4; 1Biological
Sciences, University of Delaware, Newark, DE,
2
Biochemistry & Cell Biology, Rice University,
Houston, TX, 3Materials Science & Engineering,
University of Delaware, Newark, DE, 4Center for
Translational Cancer Research, Helen F. Graham
Cancer Center & Research Institute, Newark, DE.
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Chondrogenic Transdifferentiation Of Human
Dermal Fibroblasts Stimulated With Cartilage
Derived Morphogenetic Protein1
S. Yin; National tissue engineering center, Shanghai,
CHINA.
A Microfluidic Platform for Parallel Analysis of In
Situ Patterned 3-D Liver Organoids
A. Skardal1, M. Devarasetty1, A. Atala1, S. Soker1, A.
Hall2; 1Institute for Regenerative Medicine, Wake
Forest Baptist Medical Center, Winston-Salem,
NC, 2Biomedical Engineering, Wake Forest Baptist
Medical Center, Winston-Salem, NC.
The Effect of FGF and VEGF in the Presence
of Collagen on Human Foreskin Fibroblast
Proliferation, Migration, and Integrin Expression
V. Day, S. Elliott, K. Najaryan, C. Ngo, N. Sarris, M.
McCoy, B. Tawil; Biomedical Engineering, CSUCI,
Camarillo, CA.
Electrical Stimulation of iPSC-Derived
Cardiomyocytes in a 3D Tissue Matrix Inside a
Microfluidic Device
S. F. Lam, M. G. Simon, D. D. Tran, L. F. Alonzo, N.
Flohn, A. P. Lee, S. C. George; University of California,
Irvine, Irvine, CA.
Human iPS Cell Based Cardiac Microtissue Platform
for Predictive Toxicity Studies
K. Ronaldson, S. Ma, T. Chen, K. Yeager, D. Sirabella,
G. Vunjak-Novakovic; Biomedical Engineering,
Columbia University, New York, NY.
Fiber Based Imaging on Electrospun Scaffold
E. Sapoznik1, G. Niu2, P. Lu3, Y. Zhou2, T. Criswell1, F.
Marini2, Y. Xu3, S. Soker2; 1Biomedical Engineering,
Wake Forest Institute for Regenerative Medicine,
Winston Salem, NC, 2Wake Forest Institute for
Regenerative Medicine, Winston Salem, NC,
3
Electrical and Computer Engineering, Virginia Tech,
Blacksburg, VA.
Dextran-based Fluorescent Nanoprobes for
Efficient Sentinel Lymph Node Mapping
T. Dai; Shanghai Key Laboratory of Tissue
Engineering, National Tissue Engineering Center of
China, Shanghai, Shanghai, CHINA.
Imaging Growth Factor Gradients in Biomaterial
Scaffolds
B. AKAR, S. Somo, K. Tichauer, E. Brey; Biomedical
Engineering Department, Illinois Institute of
Technology, Chicago, IL.
POSTER PRESENTATIONS
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Influence Of Dopamine Coating On Autofluorescence For Improved Molecular Imaging
G. Niu1, E. Sapoznik1, P. Lu2, T. Criswell1, A. Mohs1, Y.
Xu2, S. Soker1; 1Wake Forest University, Institute for
Regenerative Medicine, Winston-Salem, NC, 2Virginia
Tech, Department of Electrical and Computer
Engineering, Blacksburg, VA.
Magnetic Resonance Imaging to Quantify Tissue
Damage in a Rodent Ischemic Injury Model
A. Mohs, B. Rowe, B. Harrison, G. Christ; Wake Forest
Institute for Regenerative Medicine, Winston-Salem,
NC.
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407
Non-invasive Assessment of an Engineered
Endothelium via Iron Oxide Nanoparticles and
Magnetic Resonance Imaging
B. Jiang1, D. Kats1, T. Meade2, G. Ameer1; 1Biomedical
Engineering Department, Northwestern University,
Evanston, IL, 2Department of Chemistry,
Northwestern University, Evanston, IL.
Differentiating Engineered Bone from Cartilage
using Diffusion Tensor MRI for Osteochondral Tissue
Engineering
S. Majumdar1, D. Dorcemus2, S. Nukavarapu2, M.
Kotecha1; 1Bioengineering, University of Illinois
at Chicago, Chicago, IL, 2Orthopaedic Surgery,
University of Connecticut Health Center, Chicago, CT.
High Field Sodium MRI for Early Stage In Vitro
Assessment of GAG in Engineered Cartilage
P. Pothirajan1, D. Dorcemus2, S. Nukavarapu2, M.
Kotecha1; 1University of Illinois at Chicago, Chicago,
IL, 2Orthopaedic Surgery, University of Connecticut
Health Center, Farmington, CT.
Method for Identification and Characterization of
Colony Founding Connective Tissue Progenitors
E. Kwee1, K. Powell2, G. Muschler3; 1Biomedical
Engineering, Case Western Reserve University,
Cleveland, OH, 2Biomedical Informatics, The Ohio
State University, Columbus, OH, 3Biomedical
Engineering, Cleveland Clinic, Cleveland, OH.
Non-Invasive Tracking of Muscle Precursor Cells for
Sphincter Muscle Engineering
D. Haralampieva1, S. Salemi1, T. Betzel2, I. Dinulovic3,
S. Kraemer2, T. Sulser1, C. Handschin3, S. Ametamey2,
D. Eberli1; 1Urology, University Hospital Zurich, Zurich,
SWITZERLAND, 2Radiopharmaceutical Science,
ETHZ, Zurich, SWITZERLAND, 3Biozentrum Basel,
Basel, SWITZERLAND.
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Phase-based X-ray Imaging Techniques for
Cartilage Tissue Engineering Applications in situ
and in vitro
Z. Izadifar1, G. Belev2, L. D. Chapman3, X. B. Chen4;
1
Biomedical Engineering, University of Saskatchewan,
Saskatoon, SK, CANADA, 2Biomedical Imaging and
Therapy (BMIT) Beamline, Canadian Light Source,
Saskatoon, SK, CANADA, 3Anatomy and Cell
Biology, University of Saskatchewan, Saskatoon, SK,
CANADA, 4Mechanical Engineering, University of
Saskatchewan, Saskatoon, SK, CANADA.
Altered Structure of Electrospun Vascular Grafts
Promotes Different Phenotypic Expression of Innate
Immune Cells
D. Abebayehu1, A. J. Spence2, S. A. Sell3, G. Bowlin4,
J. J. Ryan2; 1Department of Biomedical Engineering,
Virginia Commonwealth University, Richmond, VA,
2
Department of Biology, Virginia Commonwealth
University, Richmond, VA, 3Department of Biomedical
Engineering, Saint Louis University, St. Louis, MO,
4
Department of Biomedical Engineering, University
of Memphis, Memphis, TN.
Different Culture Conditions Modulate
Immunological Properties of Adipose Stem Cells
M. Patrikoski, J. Sivula, B. Mannerström, S. Miettinen;
BioMediTech, Institute of Biosciences and Medical
Technology, Tampere, FINLAND.
Effects of Age-Related Changes in Biomechanical and
Biochemical Properties Upon Host Response to ECM
S. LoPresti, L. Zhang, C. Dearth, B. Brown;
Bioengineering, University of Pittsburgh, Pittsburgh, PA.
Immune response to respiratory antigen in the
Mucosal Tissue Equivalent Model
A. Mahmood; Sanofi Pasteur, Orlando, FL.
Immunomodulatory Biomaterials for Regenerative
Medicine
W. F. Liu, F. Y. McWhorter, Y. K. Kim, T. Wang;
Biomedical Engineering, University of California
Irvine, Irvine, CA.
Xenogeneic M2-polarization of Macrophages by
Undifferentiated and Differentiated Adipose Tissuederived Stem Cells
T. C. Santos, D. B. Rodrigues, M. T. Cerqueira, R.
P. Pirraco, A. P. Marques, R. L. Reis; 3B’s Research
Group, Headquarters European Institute of
Excellence on TERM, ICVS-3B’s — PT Government
Associate Laboratory, Braga/Guimarães, Portugal,
Guimaraes, PORTUGAL.
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Myostatin’s Effect on Adiposed-Derived
Mesenchymal Stem Cell Gene Expression
C. Guy, M. Beigel, E. Cunningham, D. Doroski;
Biology, Franciscan University of Steubenville,
Steubenville, OH.
-D Bioprinting of Skeletal Muscle Constructs for
Reconstruction
J. Kim, Y. Seol, I. Ko, H. Kang, S. Lee, A. Atala, J.
J. Yoo; Wake Forest Institute for Regenerative
Medicine, Winston-Salem, NC.
3
Fibrin Microbeads for Pre-Vascularization of Bone
Tissue
J. K. Gandhi1, J. P. Fisher2, M. C. Yoder3, E. M.
Brey1; 1Biomedical Engineering, Illinois Institute of
Technology, Chicago, IL, 2University of Maryland,
College Park, MD, 3Indiana University School of
Medicine, Indianapolis, IN.
Hydrogels and Microparticles Function as
Supporting Materials for Stem Cell Delivery
J. Sellathurai1, L. H. Jørgensen2, S. M. Knudsen2, T.
Thedchanamoorthy2, E. K. Hejbøl2, H. D. Schrøder1;
1
Department of pathology, Odense University
Hospital, Odense C, DENMARK, 2Institute of Clinical
Research, University of Southern Denmark, Odense
C, DENMARK.
Stability of Osteochondral Grafts in the Knee
P. Bowland, J. Fisher, E. Ingham, L. Jennings, S.
Russell; School of Mechanical Engineering, Institute
of Medical and Biological Engineering, Leeds,
UNITED KINGDOM.
423
426
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428
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430
The Use of Urinary Bladder Matrix in the
Reconstruction of Combat Related Extremity
Wounds
M. E. Fleming; Orthopedic Surgery, Walter Reed
National Military Medical Center, Bethesda, MD.
D Printed Bioactive Nanostructured Scaffolds for
Enhanced Osteochondral Regeneration
N. J. Castro, L. G. Zhang; The George Washington
University, Washington, DC.
3
Biodegradable Polymer Modified Magnesium Based
Scaffold For Bone Tissue Engineering
K. Wong1, P. Chu2, K. Luk1, K. Cheung1, K. Yeung1;
1
Orthopaedics and Traumatology, The University of
Hong Kong, Pokfulam, HONG KONG, 2Physics and
Materials Science, City University of Hong Kong,
Kowloon Tong, HONG KONG.
-D Bioprinting for Muscle-Tendon Unit
Regeneration
T. Merceron, J. Lee, C. Kengla, H. Kang, H. Kim, S.
Lee, J. J. Yoo, A. Atala; Wake Forest Institute for
Regenerative Medicine, Winston-Salem, NC.
3
TERMIS–AM • 2014
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Bioartificial Muscle Constructs : 3 Dimensional Coculture In The Presence Of Mechanical Stress And
Overstress As A Model Of Tendon And Muscle Injury
And Repair.
J. Volmer, A. Amegashie, B. Levin, D. Grant, A. Banes;
Flexcell International, Hillsborough, NC.
Matrix Microstructure And Local Mechanics Affect
The Cellularity And Repair Potential Of The Knee
Meniscus
F. Qu, M. Pintauro, J. Esterhai, M. Fisher, R. Mauck;
Orthopaedic Surgery, University of Pennsylvania,
Philadelphia, PA.
The Role Of Heat Shock Protein 70 In The Heat
Enahnced Osteogenesis Of Human Mesenchymal
Stem Cells
C. Li, S. Wang; Biomedical Engineering, City
University of New York/City College, New York, NY.
Isolation and Characterization of Rat Skeletal
Muscle Derived Vascular Endothelial Cells
Y. Zhou, S. Soker, T. Criswell; Wake Forest Institute of
Regenerative Medicine, Winston Salem, NC.
Negative Pressure-Assisted Decellularization of
Skeletal Muscle For Regenerative Surgery
S. W. Jordan1, W. Xu1, A. E. Jakus2, C. Chavez-Munoz1,
S. J. Hong1, T. A. Mustoe1, R. N. Shah2, R. D. Galiano1;
1
Plastic Surgery, Northwestern University, Chicago,
IL, 2Materials Science and Engineering, Northwestern
University, Chicago, IL.
The Relationship Between Myogenic Differentiation
And Integrin Expression Using Anisotropy
M. McClure1, N. Clark2, S. Hyzy3, R. OlivaresNavarrete3, Z. Schwartz3, B. Boyan3; 1Physical
Medicine and Rehabilitation, Hunter Holmes
McGuire Veterans Affairs Medical Center, Richmond,
VA, 2Biology, Virginia Commonwealth University,
Richmond, VA, 3Biomedical Engineering, Virginia
Commonwealth University, Richmond, VA.
The Effect of Physiologic Loading Patterns on
Native-like Spatial Organization and Development
in Tissue Engineered Menisci
J. L. Puetzer, L. J. Bonassar; Biomedical Engineering,
Cornell University, Ithaca, NY.
Apical Papilla From Human Teeth Promotes
Functional Recovery After Rat Spinal Cord Injury
P. De Berdt1, J. Vanacker1, J. Leprince1, B. Ucakar1, O.
Schakman2, R. Deumens2, A. des Rieux1; 1Advanced
Drug Delivery and Biomaterials, Université
Catholique de Louvain, Bruxelles, BELGIUM, 2Institute
of Neurosciences, Université Catholique de Louvain,
Bruxelles, BELGIUM.
POSTER PRESENTATIONS
433
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441
Engineering Neurotrophic Factor Gradients to
Direct Human Schwann Cell Migration on Aligned
Electrospun Fiber Matrix
K. D. Krick1, Y. Huang2, R. A. Martin2, P. C. Searson2, A.
Khademhosseini3, A. Hoke1, H. Mao2; 1Johns Hopkins
School of Medicine, Baltimore, MD, 2Johns Hopkins
University, Baltimore, MD, 3Harvard-MIT, Cambridge, MA.
Sustained Local Delivery Of Paclitaxel From
Aligned, Electrospun Poly(lactic-acid) Microfibers
Promotes Axonal Extension In Vitro
J. Roman1, A. Hurtado2, H. Mao3; 1Biomedical
Engineering, Johns Hopkins School of Medicine,
Baltimore, MD, 2Neuroscience, Johns Hopkins
University, Baltimore, MD, 3Materials Science and
Engineering, Johns Hopkins University, Baltimore, MD.
Engineered Protein Hydrogels to Facilitate
Neuronal Process Extension
K. J. Lampe; Chemical Engineering, University of
Virginia, Charlottesville, VA.
Graphene Nanoplatelet Laden Hydrogel for Efficient
Electrical Stimulation and Neural Regeneration
C. M. O’Brien, L. G. Zhang; Mechanical and
Aerospace Engineering, The George Washington
University, Washington, DC.
Mechanical Growth of Astrocyte Processes to
Create Tissue Engineered Living Scaffolds for
Central Nervous System Repair
K. Katiyar, C. Winter, D. K. Cullen; Neurosurgery,
Center for Brain Injury and Repair, University of
Pennsylvania, Philadelphia, PA.
442
443
444
447
448
449
Phenotypic Characterization of NSC-34 Cells, a
Motor Neuron Cell Line
L. M. Walker, J. B. Leach; University of Maryland
Baltimore County, Baltimore, MD.
SILK : The Possible Biomaterial As a Equilibrium for
Corneal Endothelium
E. Kim, G. Khang; Chonbuk National University,
Jeonju, KOREA, REPUBLIC OF.
Culture And Characterization Of Human Limbal
Stem Cells On Hydrophobic Contact Lenses
J. GRANADOS-MONTIEL1, M. Sánchez-Corza2,
C. LANDA-SOLIS1, C. ORTEGA SANCHEZ1, J.
Carmona-Hernández2, E. BAROJAS-WEBER2,
C. IBARRA1; 1TISSUE ENGINEERING, NATIONAL
INSTITUTE OF REHABILITATION, MEXICO, MEXICO,
2
Ophtalmology Department, NATIONAL INSTITUTE
OF REHABILITATION, MEXICO, MEXICO.
450
451
Development of a Novel Method for the DeEpithelialization of Amniotic Membrane
J. L. Wehmeyer, B. J. Lund, P. R. Edsall, D. O. Zamora;
Ocular Trauma, U.S. Army Institute of Surgical
Research, Fort Sam Houston, TX.
Establishment of the Co-culture System for
Conjunctival Goblet Cells and Lacrimal Glands
N. Lu1, M. P. Grant2, J. H. Elisseeff2; 1Johns Hopkins
University, Baltimore, MD, 2Wilmer Eye Institute,
Johns Hopkins University, Baltimore, MD.
Kinetics of Retinal Regeneration
A. D. Cook, C. Burns, J. Reidhead, C. Jackson;
Brigham Young University, Provo, UT.
Optimizing The Differentiation Of Enteric Neural
Progenitor Cells In Bioengineered Gut Derived
Smooth Muscle Cell Constructs For Implantation
S. L. Rego, S. Raghavan, E. Zakhem, K. N. Bitar; Wake
Forest Institute of Regenerative Medicine, Wake
Forest School of Medicine, Winston-Salem, NC.
Self-assembling Peptide Hydrogels For Support Of
Neural Stem Cell Transplants And Implications For
Tissue Repair
A. Rodriguez1, R. Williams2, C. Parish3, D. Nisbet1; 1The
Australian National University, Canberra, AUSTRALIA,
2
Deakin University, Melbourne, AUSTRALIA, 3Florey
Neuroscience Institute, Melbourne, AUSTRALIA.
Ectopic Regeneration of Endometrium-like Tissue in
vivo using Cell Sheet Technology
S. Takagi1, T. Shimizu1, G. Kuramoto2, K. Ishitani2, H.
Matsui2, T. Okano1; 1Institute of Advanced Biomedical
Engineering and Science, Tokyo Women’s Medical
University, Tokyo, JAPAN, 2Department of Obstetrics
and Gynecology, Tokyo Women’s Medical University,
Tokyo, JAPAN.
Endothelialized Biomimetic Microfluidic Oxygen
Transfer Device
A. A. Epshteyn1, E. Flores1, A. Koo2, G. GarciaCardena2, J. T. Borenstein1; 1Biomedical Engineering,
Draper Laboratory, Cambridge, MA, 2Department
of Pathology, Bridham & Women’s Hospital and
Program in Developmental and Regenrative Biology,
Harvard Medical School, Boston, MA.
Novel Fully Autologous Tissue Engineered Urinary
Bladder Model
H. Orabi, A. Rousseau, S. Bolduc; Surgery, Laval
University, Quebec, QC, CANADA.
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453
454
455
456
457
Organotypic Culture to Rapidly Assess Potential
Bioapplications for Silk Fibroin-based Materials
J. DUVAL1, T. DINIS1, G. VIDAL1, P. VIGNERON1, D.
KAPLAN2, C. EGLES1; 1UMR 7338 BiomecaniqueBioingenierie, Universite de Technologie de
Compiegne, COMPIEGNE, FRANCE, 2Biomedical
engineering, Tufts University, MEDFORD, MA.
Hyaluronic Acid Hydrogel Development for
Increased SDF-1α Sensitivity in Neural Stem Cells
C. Addington1, C. Millar-Haskell1, J. Heffernan1,
R. Sirianni2, S. Stabenfeldt1; 1School of Biological
and Health Systems Engineering, Arizona State
University, Tempe, AZ, 2Barrow Brain Tumor Research
Center, St. Joseph’s Hospital and Medical Center,
Phoenix, AZ.
458
459
460
Porosity and Surface Features of Additively
Manufactured “Trabecular Titanium” Constructs
Affect Osteoblast Phenotype
A. Cheng1, A. Humayun2, D. Cohen2, B. Boyan2, Z.
Schwartz2; 1Georgia Institute of Technology, Atlanta, GA,
2
Virginia Commonwealth University, Richmond, VA.
Porous Decellularized Adipose Tissue Microcarriers
for Adipose-derived Stem Cell Expansion
C. Yu1, L. Flynn2; 1Chemical Engineering, Queen’s
University, Kingston, ON, CANADA, 2Chemical
Engineering, Western University, London, ON,
CANADA.
The Third Strategy in Tissue Engineering:
Lockyballs Design, Fabrication and Material Testing
for Rapid In Situ 3D Tissue Biofabrication
R. Rezende1, F. Pereira1, A. Ovsianikov2, L. Baptista3,
K. Da Silva4, M. Farsari5, J. Da Silva1, V. Mironov1;
1
Division of 3D Technologies, Renato Archer
Information Technology Center, Campinas, BRAZIL,
2
Institute of Materials Science and Technology,
Technical University of Vienna, Vienna, AUSTRIA,
3
Division of Bioengineering, Federal University of
Rio de Janeiro (UFRJ), Duque de Caxias, BRAZIL,
4
Division of Bioengineering, Federal University of
Rio de Janeiro (UFRJ), Rio de Janeiro, BRAZIL,
5
Foundation for Research and Technology-Hellas,
University of Crete, Heraklion, Crete, GREECE.
Rapid Prototyped Polymer/Hydroxyapatite
Composite Scaffolds with Hydration-Induced SelfFixation Behavior
A. Kutikov, J. Song; Orthopedics & Physical
Rehabilitation, Cell & Developmental Biology,
University of Massachusetts Medical School,
Worcester, MA.
463
464
465
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The Effects of a Bioactive Modification of
Decellularized Matrix on Protein C Activation,
Coagulation and Platelet Accumulation
J. Glynn1, E. Polsin2, M. Hinds1; 1Biomedical
Engineering, Oregon Health & Science University,
Portland, OR, 2University of Portland, Portland, OR.
Hydrogel Polymer Library for Developing Induced
Pluripotent Stem Cell Derived Cardiac Patches
A. Joaquin1, N. A. Peppas1, J. Zoldan2; 1McKetta
Department of Chemical Engineering, University
of Texas at Austin, Austin, TX, 2Department of
Biomedical Engineering, University of Texas at
Austin, Austin, TX.
Anti-infective Polycaprolactone-based Electrospun
Composite Fibers As Guided Tissue/bone
Regeneration Membranes: Fabrication and In Vitro/
in Vivo Evaluation
R. Shi1, J. Xue2, D. Chen1, L. Zhang2; 1Beijing Research
Institute of Traumatology and Orthopaedics, Beijing,
CHINA, 2Beijing University of Chemical Technology,
Beijing, CHINA.
Bioengineering Human Corneal Endothelium With
Electrospun Scaffold
G. Niu, Z. Zhang, M. Giegengack, S. Soker; Wake
Forest University, Institute for Regenerative Medicine,
Winston-Salem, NC.
The Effect of Terminal Sterilization on Material
Properties and In Vivo Remodeling of a Porcine
Dermal Biologic Scaffold
C. Dearth, C. Carruthers, J. Reing, C. Ranallo, E.
Kollar, P. Crapo, S. Johnson, S. Badylak; McGowan
Institute for Regenerative Medicine, The University of
Pittsburgh, Pittsburgh, PA.
Magnetically Controllable 3D Microtissues Based on
Magnetic Microcryogels
W. Liu1, Y. Li1, S. Feng2, J. Ning3, H. Chen3, Y. Du1;
1
Department of Biomedical Engineering, Tsinghua
Universtiy, Beijing, CHINA, 2Department of
Biomedical Engineering, Beihang University, Beijing,
CHINA, 3Center for Biomedical Imaging Research &
Department of Biomedical Engineering, School of
Medicine, Tsinghua Universtiy, Beijing, CHINA.
Calcium Tranexamate : A Novel Protease Inhibitor
and Hemostat
B. Bordoloi1, N. Sarma2, R. Eisenberg3; 1Bordoloi
Biotech LLC, Bridgewater, NJ, 2Washington
University in St. Louis, Saint Louis, MO, 3Frontier
Biopharm LLC, Richmond, KY.
Cellular-Scale Surface Modification Increases
Osteogenic Protein Expression
M. Blackmore, S. Hunter, C. Saylor; Research and
Development, Community Tissue Services, Kettering, OH.
POSTER PRESENTATIONS
468
469
470
471
472
473
474
Preparation and Characterization of Nanofiberloaded Hyaluronic Acid Hydrogel for Soft Tissue
Repair
R. Martin1, S. Reddy2, J. Choi1, X. Jiang1, X. Li1, J.
Sacks2, H. Mao1; 1Materials Science & Engineering,
Johns Hopkins University, Baltimore, MD, 2Plastic
Surgery, Johns Hopkins Medical Institutions,
Baltimore, MD.
Determining the Integrity of Decellularized Porcine
Kidney Scaffolds
N. Poornejad, C. Fronk, M. House, W. Kirkham, G.
Holden, J. Nielsen, J. Wisco, B. Roeder, A. Cook;
Chemical Engineering, Brigham Young University,
Provo, UT.
Antibiotic-loaded Keratin Hydrogels Prevent
Infection in a Full-thickness Porcine Excision
Wound
D. Roy1, C. Kowalczewski2, R. Hall2, L. Burnett3, S.
Tomblyn3, J. Saul2, R. Christy1; 1Extremity Trauma and
Regenerative Medicine, United States Army Institute
of Surgical Research, Fort Sam Houston, TX, 2Miami
University, Oxford, OH, 3KeraNetics, Winston-Salem, NC.
In Vitro And In Vivo Evaluation Of Bone Formation
using Solid Freeform Fabrication-based Bone
Morphogenic Protein-2 Releasing PCL/PLGA
Scaffolds
K. Shim, Y. Yun, S. Kim, H. Song; College of Medicine,
Korea University, seoul, KOREA, REPUBLIC OF.
Scaffold For Cell Culture Made By Electrospun
Keratin Nanofibers
K. SAWADA1, H. GOTO2, Y. SAKA2, T. AOYAMA2, T.
FUJISATO2; 1Integrated Life, Osaka Seikei College,
Osaka, JAPAN, 2Osaka Institute of Technology,
Osaka, JAPAN.
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476
477
478
479
Neural Cell Behavior On A Decellularized Brain
Prepared By High-hydrostatic Pressure.
T. Kimura1, S. Honda1, T. Soma1, K. Nam1, T. Fujisato2,
I. Suzuki3, A. Kishida1; 1Institute of Biomaterials and
Bioengineering, Tokyo Medical and Dental University,
Tokyo, JAPAN, 2Department of Bioengineering,
Osaka Institute of Technology, Osaka, JAPAN,
3
Department of Electronics and Intelligent Systems,
Tohoku Institute of Technology, Tokyo, JAPAN.
Enhancement Of Subcutaneous Tissue Infiltration
Into Polyethylene Porous Scaffolds By Heparin/bfgf
Immobilization
S. Kakinoki1, Y. Sakai1, T. Fujisato2, T. Yamaoka1;
1
Department of Biomedical Engineering, National
Cerebral and Cardiovascular Center Research
Institute, Suita, Osaka, JAPAN, 2Department of
Biomedical Engineering, Graduate School of
Engineering, Osaka Institute of Technology, Osaka,
JAPAN.
480
D Hybrid Membrane Based Structure: A Novel
Approach For Tissue Engineering Scaffold
R. Suntornnond, J. An, W. Yeong, C. Chua; Nanyang
ADDITIVE MANUFACTURING CENTRE, SCHOOL
OF MECHANICAL & AEROSPACE ENGINEERING,
Nanyang Technological University, Singapore,
SINGAPORE.
3
A High Throughput Combinatorial Biomaterial
Screening Platform for Probing Cell Responses
S. Ramamoorthy1, R. Jacobson2, J. Malcovitch2,
C. Bertucci3, G. Saunders2, D. Thompson3, P.
Karande1; 1Chemical and Biological Engineering,
Rensselaer Polytechnic Institute, Troy, NY, 2Center for
Automation Technologies and Systems, Rensselaer
Polytechnic Institute, Troy, NY, 3Biomedical
Engineering, Rensselaer Polytechnic Institute, Troy, NY.
Complete Cell Killing by Applying high hydrostatic
pressure for Extracellular Matrix Preparation
A. Mahara1, N. Morimoto2, T. Fujisato3, T. Yamaoka1;
1
Department of Biomedical Engineering, National
Cerebral and Cardiovascular Center Research
Institute, Suita, JAPAN, 2Department of Plastic and
Reconstructive Surgery, Kansai Medical University,
Hirakata, JAPAN, 3Department of Biomedical
Engineering, Osaka Institute of Technology, Osaka,
JAPAN.
Elastin Incorporated Electrochemically Aligned
Collagen Fibers for Vascular Applications
T. Nguyen1, C. Bashur2, V. Kishore1; 1Chemical
Engineering, Florida Institute of Technology,
Melbourne, FL, 2Biomedical Engineering, Florida
Institute of Technology, Melbourne, FL.
Hybrid Electrospun Scaffold For Muscle
Bioengineering
O. Evrova1, R. Tauscher2, G. Palazzolo3, V. Milleret4, M.
Zenobi-Wong3, T. Sulser5, J. Buschmann6, D. Eberli2;
1
Department of Health Sciences and Technology,
ETH Zürich, Zürich, SWITZERLAND, 2Department of
Urology, Laboratory for Urologic Tissue Engineering
and Stem Cell Therapy, University Hospital Zürich,
Zürich, SWITZERLAND, 3Departement of Health
Science and Technology, Cartilage Engineering and
Regeneration, ETH Zürich, Zürich, SWITZERLAND,
4
Department of Obstetrics, University Hospital
Zürich, Zürich, SWITZERLAND, 5Department
of Urology, University Hospital Zürich, Zürich,
SWITZERLAND, 6Department of Reconstructive
Surgery, University Hospital Zürich, Zürich,
SWITZERLAND.
Structural Characteristics of Silkworm Cocoon and
Its Application
H. Kweon, Y. Jo, K. Lee, J. Yeo; National Academy of
Agricultural Science, Suwon, KOREA, REPUBLIC OF.
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Structural Characteristics of Regenerated wild
silkworm Silk Fibroin
k. lee, H. Kweon, y. jo, h. kim; National Academy of
Agricultural Science, Suwon, KOREA, REPUBLIC OF.
Optimization of Decellularization of Porcine Hearts
N. Momtahan1, S. Sukavaneshvar2, B. Roeder3, A.
Cook1; 1Chemical Engineering, Brigham Young
University, Provo, UT, 2Thrombodyne Inc., Salt Lake
City, UT, 3Biology, Brigham Young University, Provo, UT.
Development Of Heparin Immobilized Scaffolds For
Bone Tissue Engineering Using Gamma-irradiation
S. Jeong, J. Jeong, J. Choi, H. Gwon, J. Park, Y. Shin,
Y. Nho, Y. Lim; Advanced Radiation Technology
Institute, Korea Atomic Energy Research Institute,
Jeongeup-si, KOREA, REPUBLIC OF.
488
489
490
Biodegradable Shortened Electrospun Nanofibers
Scaffold For Big Sized Spheroid Formation
H. Kobayashi, S. Hattori, T. Honda; WPI-MANA,
National Institute for Materials Science, Tsukuba,
JAPAN.
492
Fabrication and Evaluation of Electrospun Antiinfection Guided Tissue Regeneration Membrane
J. Xue1, R. Shi2, D. Chen2, L. Zhang1; 1Beijing
University of Chemistry Technology, Beijing, CHINA,
2
Laboratory of Bone Tissue Engineering of Beijing
Research Institute of Traumatology and Orthopaedics,
Beijing, CHINA.
493
New Decellularization Process for Trachea
Replacement
D. Giraldo1, J. Garcia2, D. Garciadiego2, A. Sotres3,
C. Piña1; 1Instituto de Investigaciones en Materiales,
Universidad Nacional Autonoma de Mexico, Mexico
D.F., MEXICO, 2Unidad de Ingeniería de Tejidos
Terapia Celular y Medicina Regenerativa, Instituto
Nacional de Rehabilitación, Mexico D.F., MEXICO,
3
Departamento de Investigación en Cirugía
Experimental, , Instituto Nacional de Enfermedades
Respiratorias “Ismael Cossio Villegas”, Mexico D.F.,
MEXICO.
Mid To Long Compatibility Evaluation Of Fibroin
Nanofiber Scaffold In Rabbit Cornea
H. Kobayashi1, S. Hattori1, T. Honda1, D. Terada1, T.
Kameda2, Y. Tamada3; 1WPI-MANA, National Institute
for Materials Science, Tsukuba, JAPAN, 2Silk materials
research unit, National Institute of Agrobiological
Sciences, Tsukuba, JAPAN, 3Silk materials research
unit, National Institute of Agrobiological Sicences,
Tsukuba, JAPAN.
TERMIS–AM • 2014
495
496
Polydopamine Deposition On The Substrates With
Different Surface Property
Y. Lim, Y. Shin, S. Jeong, J. Park, H. Gwon; Advanced
Radiation Technology Institute, Korea Atomic Energy
Research Institute, Jeongeup-si, KOREA, REPUBLIC OF.
Osteogenesis Induction of Periodontal Ligament
Cells onto Bone Morphogenic Protein-2 Immobilized
PCL Fibers
J. Lee1, Y. Yun2, S. Kim1, H. Song1; 1Korea University,
Seoul, KOREA, REPUBLIC OF, 2Korea University
Medical Center, Guro, Seoul, KOREA, REPUBLIC OF.
Cell-Seeded Thin Film Nickel-Titanium Heart Valve
J. Boldt1, A. Engel1, K. Loger2, R. Lima de Miranda2, G.
Lutter1, E. Quandt2; 1Department for Cardiovascular
Surgery, University Hospital Schleswig-Holstein, Kiel,
GERMANY, 2Institute of Materials Science, ChristianAlbrechts-University of Kiel, Kiel, GERMANY.
The Effect of Alendronate-Loaded
Polycarprolactone Nanofibrous Scaffolds on
Osteogenic Differentiation of Adipose-Derived
Stem Cells in Bone Tissue Regeneration
K. Shim, Y. Yun, S. Kim, H. Song; College of Medicine,
Korea University, seoul, KOREA, REPUBLIC OF.
PEG-Gelatin and Carrageenan-Gelatin
Supermacroporous Cryogel Matrices for Soft Tissue
Engineering Applications
A. SHARMA; DEPT. OF BIOLOGICAL SCIENCES, BITS
PILANI, K.K BIRLA GOA CAMPUS, GOA, VASCO,
GOA, INDIA.
Nano Silver Substituted Hydroxyapatite, Gelatin,
Alginate and SPION Composite Fibrous scaffolds
for Bone tissue Engineering
B. Das, P. Dadheech, P. Srivas, P. Pal, S. Dhara; School
of Medical Science & Technology, Indian Institute of
Technology, Kharagpur, Kharagpur, INDIA.
Preparation Of Inactivated Dermal Substitute From
Melanocytic Nevus Using High-hydrostatic Pressure
C. JINNO1, N. Morimoto2, L. Pham Hieu3, A. Mahara4,
T. Fujisato5, T. Yamaoka6, S. Suzuki1; 1Plastic and
Reconstructive Surgery, Kyoto University, Kyoto,
JAPAN, 2Plastic and Reconstructive Surgery,
KansaiMedicalUniversity, Osaka, JAPAN, 3Plastic
and Aesthetic Surgery, Pham Ngoc Thach University
of Medicine, HCMC, VIET NAM, 4Biomedical
Engineering, National Cerebral and Cardiovascular
Center Research Institute, Suita, Osaka, JAPAN,
5
Biomedical Engineering, Osaka Institute of
Technology, Osaka, JAPAN, 6Biomedical Engineering,
National Cerebral and Cardiovascular Center
Research Institute, Osaka, JAPAN.
POSTER PRESENTATIONS
497
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500
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Incorporation of Photo-Carbon Monoxide Releasing
Materials into Electrospun Scaffolds for Engineering
Vascular Grafts
E. K. Michael1, N. Abeyrathna2, K. Birthare1, Y. Liao2, C.
A. Bashur1; 1Biomedical Engineering, Florida Institute
of Technology, Melbourne, FL, 2Chemistry, Florida
Institute of Technology, Melbourne, FL.
Gel Elasticity And Gelation Kinetics As Parameters
In The Development And Quality Control Of
Hydrogels For Medical Products
T. Andersen, P. Auk-Emblem, J. Melvik, M. Dornish;
FMC BioPolymer/NovaMatrix, Sandvika, NORWAY.
Effect of Biomaterial Scaffolds on 3D Shape of Stem
Cells
S. J. Florczyk1, D. Juba2, A. Cardone2, S. Sarkar1, D.
Chen1, P. J. Baker1, P. Bajcsy2, M. Brady2, C. G. Simon,
Jr.1; 1Biosystems & Biomaterials Division, National
Institute of Standards and Technology, Gaithersburg,
MD, 2Software & Systems Division, National Institute
of Standards and Technology, Gaithersburg, MD.
Characterization of Thymus Scaffolds for
Engineering Thymus Tissue
S. Ryu, A. Mondal, S. Gutierrez, J. Marco, Y. Ju, S. Lee,
A. Atala, J. Yoo, J. Jackson; Wake Forest Institute
for Regenerative Medicine (WFIRM), Wake Forest
University School of Medicine, Winston Salem, NC.
Cytocompatible Tough Hydrogel Platform with
Predicatable Degradation for Complex Composite
Scaffold Fabrications
J. Xu, E. Feng, J. Song; Department of Orthopedics &
Physical Rehabilitation, University of Massachusetts
Medical School, Worcester, MA.
Biocompatibility Of Pcl-graphene Electrospun
Scaffolds With Mouse Embryonic Stem Cell-derived
Cardiomyocytes
P. Hitscherich1, A. Aphale2, P. Patra2, E. Lee1;
1
Biomedical Engineering, New Jersey Institute of
Technology, Newark, NJ, 2Biomedical Engineering,
University of Bridgeport, Bridgeport, CT.
Honey Based Scaffolds for Engineering of Human
Oral Mucosa
M. Rajput1, A. Anura1, N. Bhandaru2, R. Mukherjee2,
R. R. Paul3, P. Banerjee1, J. Chaterjee1; 1School of
Medical Science and Technology, Indian Institute
of Technology Kharagpur, Kharagpur, INDIA,
2
Department of Chemical Engineering, Indian
Institute of Technology Kharagpur, Kharagpur, INDIA,
3
Department of Oral and Maxillofacial Pathology,
Guru Nanak Institute of Dental Science and Research,
Kolkata, INDIA.
504
505
506
507
508
509
510
511
D Printing of Highly Interconnected Porous
Nanocomposite Osteochondral Scaffolds
N. J. Castro1, L. G. Zhang2; 1The George Washington
University, Washington, DC, 2Mechanical and
Aerospace Engineering, Medicine, The George
Washington University, Washington, DC.
3
The Evaluation of Gold and Hydroxyapatite Nanografts in a Green Fluorescent Protein Porcine Model
S. E. Smith, R. White, D. Grant, S. Grant; University of
Missouri, Columbia, MO.
Three-dimensional Printing Of Shape Memory Smart
Materials For Orthopedic Tissue Regeneration
N. J. Castro1, K. Hearon2, L. G. Zhang3; 1The George
Washington University, Washington, DC, 2Chemical
Engineering, Massachusetts Institute of Technology,
Cambridge, MA, 3Mechanical and Aerospace
Engineering, The George Washington University,
Washington, DC.
Soft Tissue Scaffold Derived from Porcine Adipose
Tissue
K. Roehm, S. Madihally; Oklahoma State University,
Stillwater, OK.
D Printing of Bone Extracellular Matrix
B. P. Hung, J. P. Temple, W. L. Grayson; Biomedical
Engineering, Translational Tissue Engineering Center,
Johns Hopkins University, Baltimore, MD.
3
Vascularized Bone Grafts: Mesenchymal Stem Cells
and Endothelial Cells Coculture Stimulated by
VEGF Release
C. Piard, J. P. Fisher; Fischell Departement of
Bioengineering, University of Maryland, College Park,
MD.
Functionalization Pre-treatment: Effects On
Physical-chemical Properties Of Scaffolds
D. I Braghirolli1, V. E Helfer1, D. Gamba2, P. Pranke3;
1
Federal University of Rio Grande do Sul, Porto
Alegre, BRAZIL, 2Chemistry Institute, Federal
University of Rio Grande do Sul, Porto Alegre,
BRAZIL, 3Analysis, Federal University of Rio Grande
do Sul, Porto Alegre, BRAZIL.
Fibrin Microthread Scaffolds to Facilitate Muscle
Regeneration in a Model of Volumetric Muscle Loss
J. M. Grasman1, R. L. Page1, T. Dominko2, G. D. Pins1;
1
Biomedical Engineering, Worcester Polytechnic
Institute, Worcester, MA, 2Biology and Biotechnology,
Worcester Polytechnic Institute, Worcester, MA.
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Optimizing the Decellularization of Porcine Vocal
Folds
E. A. Wrona1, H. Born2, M. R. Amin2, R. C. Branski2,
D. O. Freytes1; 1New York Stem Cell Foundation
Research Institute, New York, NY, 2New York
University School of Medicine, New York, NY.
Improving the Mechanical Stability of ChitosanGelatin Based Injectable Hydrogel for Cardiac
Regeneration Therapy
C. J. Tormos, C. Abraham, S. V. Madihally; Chemical
Engineering, Oklahoma State University, Stillwater, OK.
521
522
Evaluation of Chitosan-Gelatin Thermo-Sensitive
Hydrogels for Bioprinting
K. Singarapu, M. V. Sundararajan; School of Chemical
Engineering, Oklahoma State University, Stillwater, OK.
524
Bioengineered Human Cell Conditioned Medium
and Extracellular Matrix-derived Materials for
Orthopedic Applications
M. P. Zimber, E. Pinney, M. Montes, G. K. Naughton;
Histogen Inc., San Diego, CA.
526
Host Stem Cell Recruitment for In Situ Muscle
Tissue Regeneration
Y. Ju, L. Shapiro, I. Ko, J. J. Yoo, A. Atala, S. Lee;
Wake Forest Institute for Regenerative Medicine,
Wake Forest School of Medicine, Winston-Salem, NC.
527
Mesenchymal Stromal Cells Retain Cellular Integrity
After Culturing on Small Intestinal Sub-Mucosa
Extracellular Matrix
T. D. Petrie, X. Lin, W. Boyd, C. Sondergaard; Surgery,
Univeristy of California Davis, Sacramento, CA.
528
Embryonically Inspired Scaffolds to Direct
Tenogenic Differentiation of Stem Cells
N. R. Schiele, J. E. Marturano, Z. Schiller, C. K. Kuo;
Biomedical Engineering, Tufts University, Medford, MA.
Effect of Three Dimensional Polycaprolactone/
Hydroxyapatite Scaffold Architecture on
Proliferation and Osteogenesis of Human Adipose
Derived Stem Cells
S. Cai1, P. Sheshadri2, R. Shirwaiker2, E. Loboa3;
1
Department of Materials Science and Engineering,
North Carolina State University, Raleigh, NC, 2Edward
P. Fitts Department of Industrial Systems and
Engineering, North Carolina State University, Raleigh,
NC, 3Joint Department of Biomedical Engineering,
University of North Carolina at Chapel Hill and North
Carolina State University, Raleigh, NC.
TERMIS–AM • 2014
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530
531
Multilayered Collagen Vitrigels for Increased
Suturability while Maintaining High Transparency
for Corneal Applications
S. Majumdar1, M. Trexler2, O. D. Schein3, J. H.
Elisseeff1; 1Translational Tissue Engineering Center,
Johns Hopkins University, Baltimore, MD, 2Applied
Physics Laboratory, Johns Hopkins University, Laurel,
MD, 3Wilmer Eye Institute, Johns Hopkins University,
Baltimore, MD.
Vascularized Tissue Formation in Hydrogels with
Controlled Porous Structure
S. I. Somo, B. Akar, A. A. Appel, E. S. Bayrak, H.
Mehdizadeh, A. Cinar, E. M. Brey; Illinois Institute of
Technology, Chicago, IL.
Nanofibrous Acellular Matrix Derived from Human
Fibroblasts
Q. Xing, K. Yates, M. Tahtinen, E. Shearier, Z.
Qian, F. Zhao; Biomedical Engineering, Michigan
Technological University, Houghton, MI.
ASC Myogenesis within a 3D Fibrin-Nanofiber
Construct
J. Gilbert, B. Ginn, P. Yilgor Huri, T. Zhang, K. Wagner,
H. Mao, W. Grayson; Biomedical Engineering, Johns
Hopkins, Baltimore, MD.
MicroTanks: SCUBA for Cells in Hypoxic
Environments
C. A. Cook, K. C. Hahn, D. L. Hutton, W. L. Grayson;
Biomedical Engineering, Johns Hopkins University,
Baltimore, MD.
Integrated Multistructural Scaffold for Interfacial
Tissue Engineering
T. He1, S. Lee2, M. W. King1; 1College of Textiles, North
Carolina State University, Raleigh, NC, 2Center for
Biomolecular Imaging, Wake Forest Institute of
Regenerative Medicine, Winston-Salem, NC.
Investigation Of Cell-scaffold Dimensional
Metrology Using 3d Melt-electrospun Scaffolds
F. Tourlomousis, R. Chang; Stevens Institute of
Technology, Hoboken, NJ.
Protein Adsorption and Cell Adhesion to
poly(MEO2MA-co-OEGMA) Thermoresponsive
Polymer Substrates
C. R. Anderson, M. Warrener; Chemical and
Biomolecular Engineering, Lafayette College, Easton, PA.
Micro-organization of Collagen Matrix in Acellular
Porcine Dermis
M. Fang, R. Owens, H. Xu; R&D, LifeCell Corporation,
Bridgewater, NJ.
POSTER PRESENTATIONS
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535
536
537
538
539
542
Thermacol: A Novel Hydrogel With Thermally
Controlled Gelation And Material Properties For
Engineering Bioartificial Tissues
A. J. banes1, J. Volmer1, D. Grant1, A. Omegashie1, M.
Wall1, B. Levin1, E. Loboa2; 1Hillsborough Business
Center, Flexcell International Corp, Hillsborough,
NC, 2Joint Dept of Biomedical Engineering, North
Carolina State University, Raleigh, NC.
543
545
Self-assembled Instructive Extracellular Matrices
N. Faruqui1, A. Bella1, J. Ravi1, S. Ray2, L. Baptiste1,
M. G. Ryadnov1; 1Biotechnology, National Physical
Laboratory, Middlesex, UNITED KINGDOM,
2
Nanotechnology, National Physical Laboratory,
Middlesex, UNITED KINGDOM.
Evaluation Of Bone Regeneration With Using Novel
Collagen, Which Has An Ability Of Cell Spheroid
Formation
S. Kunii1, E. Yamamoto2, Y. Horiuchi3, H. Ito2, M. Ida4,
Y. Hiraoka4, K. Morimoto1; 1Genetic Engineering,
Kindai University, Kinokawa, JAPAN, 2Biomedical
Engineering, Kindai University, Kinokawa, JAPAN,
3
Life Science Research Institute, Kindai University,
Osaka-sayama, JAPAN, 4Nitta Gelatin Inc., Yao,
JAPAN.
Peptide-Carbon Nanotube Hydrogels as Hybrid
Scaffolds for Tissue Engineering
M. Sheikholeslam1, S. Wheeler2, K. Duke2, M. Pritzker1,
P. Chen1; 1Chemical Engineering, University of
Waterloo, WATERLOO, ON, CANADA, 2Waterloo
Institute for Nanotechnology, University of Waterloo,
WATERLOO, ON, CANADA.
Biologic Scaffold Mediated Constructive Tissue
Remodeling in Patients with Volumetric Muscle Loss
C. Dearth1, B. Sicari1, J. Rubin2, F. Ambrosio3, M.
Boninger3, N. Turner1, A. Wyse4, E. Brown3, S. Brown2,
S. Badylak1; 1McGowan Institute for Regenerative
Medicine, The University of Pittsburgh, Pittsburgh,
PA, 2Department of Plastic Surgery, The University
of Pittsburgh, Pittsburgh, PA, 3Department of
Physical Medicine & Rehabilitation, The University
of Pittsburgh, Pittsburgh, PA, 4Department of
Radiology, The University of Pittsburgh, Pittsburgh,
PA.
Biomaterials in Aqueous Media vs. Attached State
Have Differing Effects on Cellular Processes
C. Ebert; Winston Salem State University, Winston
Salem, NC.
Chemotactic Factors Secreted From Mesenchymal
Stromal Cells Cultured On An Extracellular Matrix
V. G. Spandler, Zoe Saens, C. S. Sondergaard, M.
Robinson, X. Lin, T. Petrie; Surgery, UC Davis Medical
Center, Sacramento, CA.
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547
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549
Polymer Degradation and Mechanical Properties of
Multi-layer Electrospun Scaffolds
L. M. Ott, N. Walker, A. Farris, M. S. Detamore;
University of Kansas, Lawrence, KS.
Development Of Novel Silk Fibroin-gelatin Bioink
For 3d Cell Printing Technology
Y. Choi1, F. Pati2, S. Das3, G. Rijal2, J. Shim4, S. Kim5,
A. R. Ray6, S. Ghosh3, D. Cho2; 1Division of Integrative
Biosciences and Biotechnology, POSTECH, Pohang,
KOREA, REPUBLIC OF, 2Department of Mechanical
Engineering, POSTECH, Pohang, KOREA, REPUBLIC
OF, 3Department of Textile Technology, IIT Delhi,
New Delhi, INDIA, 4Department of Mechanical
Engineering, Korea Polytechnic University,
Siheung-si, KOREA, REPUBLIC OF, 5Department of
Otolaryngology-Head and Neck Surgery, College of
Medicine, The Catholic University of Korea, Seoul,
KOREA, REPUBLIC OF, 6Centre for Biomedical
Engineering, IIT Delhi, New Delhi, KOREA, REPUBLIC OF.
Coiled Fiber Scaffolds Embedded With Gold
Nanoparticles Improve The Performance Of
Engineered Cardiac Tissues
S. Fleischer, M. Shevach, R. Feiner, T. Dvir; Molecular
Microbiology and Biotechnology, Tel Aviv university,
Tel Aviv, ISRAEL.
In Vitro Assessment Of Resorbable Scaffold For
Skin Tissue Engineering
A. González Wusener1, I. E. Ruiz2, C. O. Arregui1, A. N.
Bolgiani3, E. B. Hermida2; 1Instituto de Investigaciones
Biotecnológicas-Instituto Tecnológico de Chascomús
(IIB-INTECH); Universidad Nacional de San Martín;
Consejo Nacional de Investigaciones Científicas
y Técnicas, San Martin, ARGENTINA, 2Escuela de
Ciencia y Tecnología, Universidad Nacional de
San Martín, San Martin, ARGENTINA, 3Centro de
Excelencia para Asistencia de Quemaduras (CEPAQ)
Fundación Benaim, Hospital Alemán, Buenos Aires,
ARGENTINA.
Modification of Peptide Self-Assembling Hydrogels
for Cell Culture Applications
L. Szkolar, A. F. Miller, A. Saiani, J. E. Gough;
The University of Manchester, Manchester,
UNITED KINGDOM.
Fabrication of Polymer Coatings with Controlled
Microtopographies Using Electrospraying
Technique
Q. Guo1, J. P. Mather2, P. T. Mather2; 1Biomedical
Engineering, Johns Hopkins University, Baltimore,
MD, 2Biomedical and Chemical Engineering, Syracuse
University, Syracuse, NY.
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Raw Material Encapsulation Influences
Differentiation Of Rat Bone Marrow Stromal Cells In
Microsphere Based Gradient Scaffolds
V. Gupta, M. Detamore; Bioengineering Graduate
Program, University of Kansas, Lawrence, KS.
Electrospinning of PLGA with Morin Fiber Scaffolds
to Cultivate with Stem Cells
S. A. Ferreira1, D. Pereira1, N. Maurmann2, P. Pranke3;
1
Hematology and Stem Cell Laboratory, Faculty of
Pharmacy, Federal University of Rio Grande do Sul,
Porto Alegre, BRAZIL, 2Hematology and Stem Cell
Laboratory, Faculty of Pharmacy; Post-graduation
Program in Physiology, Federal University of Rio
Grande do Sul, Porto Alegre, BRAZIL, 3Hematology
and Stem Cell Laboratory, Faculty of Pharmacy;
Post-graduation Program in Physiology, Federal
University of Rio Grande do Sul and Stem Cell
Research Institute, Porto Alegre, BRAZIL.
Recombinant LL37 Antimicrobial Peptide with
Collagen Tethering for Wound Healing Applications
L. D. Lozeau1, D. Kole2, R. Gasper1, C. R. Miller2, T.
Dominko2, M. W. Rolle3, T. A. Camesano1; 1Chemical
Engineering, Worcester Polytechnic Institute,
Worcester, MA, 2Biology & Biotechnology, Worcester
Polytechnic Institute, Worcester, MA, 3Biomedical
Engineering, Worcester Polytechnic Institute,
Worcester, MA.
Engineering Bone Substitutes To Modulate Bone
Homeostasis With Biomaterial Using Human
Induced Pluripotent Stem Cells
O. Jeon1, L. M. Panicker2, R. A. Feldman2, J. H.
Elisseeff1; 1Biomedical Engineering, Johns Hopkins
University, baltimore, MD, 2Microbiology and
Immunology, University of Maryland School of
Medicine, baltimore, MD.
Optimization of the Self Assembly Method of
Engineering Soft Tissues
S. Chabaud, A. Rousseau, T. Marcoux, H. Orabi,
S. Bolduc; Surgery, Laval University, Quebec, QC,
CANADA.
Bioartifical Dermal Substitutes in the Severely
Traumatized Wounded Warrior - Updates and
New Applications
M. E. Fleming, I. L. Valerio; Orthopedic Surgery,
Walter Reed National Military Medical Center,
Bethesda, MD.
Regenerative Medicine Applications In Combat
Casualty Care
M. E. Fleming, I. L. Valerio; Orthopedic Surgery,
Walter Reed National Military Medical Center,
Bethesda, MD.
TERMIS–AM • 2014
558
559
560
561
562
563
564
565
A Novel Approach to Deliver Cells in Fibrin Beads
V. Yindeeyoungyeon, B. Wu, B. Tawil; University of
California, Los Angeles, Los Angeles, CA.
Chitosan-Collagen Hydrogel Modified with
QHREDGS Peptide for Wound Healing
Y. Xiao, M. Radisic; Department of Chemical
Engineering & Applied Chemistry, University of
Toronto, Toronto, ON, CANADA.
Chitosan-pla Films Implantation In Burned Mouse
And Its Effect In Wound Healing
A. Martínez Moctezuma, Sr., N. Vazquez, A. Espadín,
H. Lecona, J. García, A. Reyes, K. Shirai, L. Tamay,
X. Lopez, A. Medina, R. Pichardo, C. Ibarra, C.
Velasquillo; Laboratorio de Biotecnología, Instituto
Nacional de Rehabilitación, Ciudad de México,
MEXICO.
Cryopreservation of Cell Sheets of Adipose Stem
Cells: Limitations and Successes
F. P. Prata1, M. T. Cerqueira2, J. Moreira-Silva2,
R. P. Pirraco2, R. L. Reis2, A. P. Marques2; 13B’s
Research Group - Biomaterials, Biodegradables
and Biomimetics, Headquarters of the European
Institute of Excellence on Tissue Engineering and
Regenerative Medicine; ICVS/3B’s - PT Government
Associate Laboratory;Department of Biomedical
Sciences and Medicine, University of Algarve,
Guimarães-Braga, PORTUGAL, 23B’s Research Group
- Biomaterials, Biodegradables and Biomimetics,
Headquarters of the European Institute of
Excellence on Tissue Engineering and Regenerative
Medicine; ICVS/3B’s - PT Government Associate
Laboratory,University of Minho, Guimarães-Braga,
PORTUGAL.
High Throughput Scale-up of Anti-inflammatory
Nanofibrous Bandages for Wound Healing
Applications
M. Mohiti-Asli, B. Pourdeyhimi, E. G. Loboa; North
Carolina State University, Raleigh, NC.
Amnion Hydrogel Accelerates Skin Wound Healing
S. V. Murphy, A. Skardal, K. Sutton, T. Reid, H.
Rebecca, L. Song, J. Jackson, A. Atala; Wake Forest
School of Medicine, Wake Forest Institute for
Regenerative Medicine, Winston-Salem, NC.
Different Growth Factor Presentation Schemes for
Enhanced Wound Healing
C. Kim, I. P. Mitchell, M. Kim, P. K. Kreeger, K. Masters;
Biomedical Engineering, University of Wisconsin,
Madison, Madison, WI.
Use of Sterilized, Lyophilized Platelets for Seeding
Provisional Matrix
N. Ramachandran, M. Hiles; R&D, Cook Biotech, West
Lafayette, IN.
POSTER PRESENTATIONS
566
567
568
569
570
571
Using Acellular Dermal Matrix for Treatment of
Partial and Full-Thickness Burns in a Porcine Model
G. Christopherson, H. Li, H. Xu; LifeCell Corporation,
Bridgewater, NJ.
Anastomoseal - Biopolymeric Patches For The
Treatment Of Colorectal Anastomosis
M. Dornish1, I. Donati2, N. Bouvy3, M. Bosco4, M.
Foulc5, W. Fediuk6; 1FMC BioPolymer/NovaMatrix,
Sandvika, NORWAY, 2University of Trieste, Trieste,
ITALY, 3Department of Surgery, University of
Maastricht, Maastricht, NETHERLANDS, 4Sigea S.r.L.,
Trieste, ITALY, 5Rescoll, Pessac, FRANCE, 6IE Impuls,
Gdansk, POLAND.
In Situ Skin Bioprinting System for Skin Repair
J. Kim, E. Alvaro, J. Marco, J. Green, K. Williams, J.
Jackson, J. Yoo, A. Atala; Institute for Regenerative
Medicine, Wake Forest School of Medicine, Winston
Salem, NC.
Hypoxia Modulates The Differentiation Potential Of
Stem Cells Of The Apical Papilla
V. Julie1, A. Viswanath1, P. De Berdt1, A. Evrard2,
P. Cani2, C. Bouzin3, O. Feron3, A. Diogenes4, J.
Leprince1, A. des Rieux1; 1Advanced Drug Delivery
and Biomaterials, Université Catholique de Louvain,
Bruxelles, BELGIUM, 2Metabolism and Nutrition
Research Group, Université Catholique de Louvain,
Bruxelles, BELGIUM, 3Pole of pharmacology,
Université Catholique de Louvain, Bruxelles,
BELGIUM, 4University of Texas Health Science Center
at San Antonio, San Antonio, TX.
Alginate- And Hyaluronic Acid-based Hydrogel
Properties Influence Dental Stem Cell Viability
L. Lambricht1, P. De Berdt1, J. Vanacker1, J. Leprince1,
A. Diogenes2, H. Goldansaz3, C. Bouzin4, V. Préat1,
C. Dupont-Gillain3, A. des Rieux1; 1Advanced Drug
Delivery and Biomaterials, Université Catholique de
Louvain, Bruxelles, BELGIUM, 2University of Texas
Health Science Center at San Antonio, San Antonio,
TX, 3Bio- and Soft Matter Unit, Université Catholique
de Louvain, Louvain-la-Neuve, BELGIUM, 4Pole of
pharmacology, Université Catholique de Louvain,
Bruxelles, BELGIUM.
Fibrin Hydrogels As Stem Cells of the Apical Papilla
(SCAP) For Regenerative Medicine.
L. Germain1, P. De Berdt1, J. Vanacker1, J. Leprince1,
A. Diogenes2, D. Jacobs1, G. Vandermeulen1, C.
Bouzin3, V. Préat1, C. Dupont-Gillain4, A. des Rieux1;
1
Advanced Drug Delivery and Biomaterials, Université
Catholique de Louvain, Bruxelles, BELGIUM,
2
University of Texas Health Science Center at San
Antonio, San Antonio, TX, 3Pole of pharmacology,
Université Catholique de Louvain, Bruxelles,
BELGIUM, 4Université Catholique de Louvain,
Louvain-la-Neuve, BELGIUM.
572
573
574
575
576
577
580
581
The Effects of FGF, TGFb, and IGF on Mesenchymal
Stem Cells Seeded on a Collagen Matrix
D. Burns, D. Hau, A. Naderkhani, J. Plat, M. McCoy, B.
Tawil; Biomedical Engineering Program, California
State University, Channel Islands, Camarillo, CA.
Development of Tissue-Specific GM-CSF Gene
Expressing System and Combined Cell Therapy in
Spinal Cord Injury Model
Y. YOU1, J. OH1, D. YOON2, Y. HA2; 1Brain Korea 21 PLUS
Project for Medical Science, Yonsei University, Seoul,
KOREA, REPUBLIC OF, 2NEUROSURGERY, Yonsei
University, Seoul, KOREA, REPUBLIC OF.
Targeted Homing of Mesenchymal Stem Cells by
Pulsed Focused Ultrasound Improves Survival and
Renal Function During Established Acute Kidney
Injury
S. Burks1, B. Nguyen1, S. Kim1, P. Tebebi1, J. Street2,
P. Yuen2, R. Star2, J. Frank1; 1NIH Clinical Center,
Bethesda, MD, 2NIDDK, Bethesda, MD.
A Standardized and Well-Characterized hMSC
Source for Translational Researchers
L. Lock1, I. Farrance1, P. Baraniak1, J. Hao2, J. Rowley1;
1
RoosterBio Inc., Frederick, MD, 2Poochon Scientific,
Frederick, MD.
Human Adipose Tissue-Derived Cells Exhibit
Donor Variability in Their Response to BMP-2 and
Dexamethasone in 3D Hydrogel Culture
J. E. Samorezov1, C. R. Everett1, E. B. Headley1, E.
Alsberg2; 1Biomedical Engineering, Case Western
Reserve University, Cleveland, OH, 2Biomedical
Engineering and Orthopedic Surgery, Case Western
Reserve University, Cleveland, OH.
Epoxomicin Affects Proliferating Neural Progenitor
Cells Of Rat
K. Youssef, M. Elhosseny, B. Sayed Ahmed; Faculty
of medicne - Toxicology department, Mansoura
university, Mansoura, EGYPT.
The Role of Autophagy in the Differentiation of
Adipose Derived Stem Cells to Functional Smooth
Muscle Cells for Urologic Tissue Engineering
S. Salemi, D. Keller, A. Mortezavi, T. Sulser, d.
eberli; Urology, University Hospital Zürich, Zürich,
SWITZERLAND.
An Injectable and Settable Cell Delivery System
Derived From In Situ Chemical Polymerization
Promote Healing In a Porcine Full-Thickness
Excisional Wound Model
R. Guo1, C. Ward2, L. Nanney1, S. Guelcher1; 1Vanderbilt
University, Nashville, TN, 2United States Army
Institute of Surgical Research, Fort Sam Houston, TX.
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Modeling Cell Viability and Vascularization in
Diffusion-Limited Grafts
D. L. Hutton, B. P. Hung, W. L. Grayson; Biomedical
Engineering, Johns Hopkins University, Baltimore, MD.
590
Novel Divalent Aptamer Assembly for Controlled
VEGF Receptor Activation
V. Ramaswamy, A. G. Monsalve, B. R. Dollinger,
J. P. Dobson, J. B. Allen; Materials Science and
Engineering, University of Florida, Gainesville, FL.
592
Production Of Glucose Stimulated Insulin Secreting
Cells From Hipscs By Scalable Three Dimensional
Suspension Bioreactor System
Y. Mihara1, K. Matsuura2, Y. Sakamoto1, T. Okano2,
N. Kokudo1, T. Shimizu2; 1Tokyo University, Tokyo,
JAPAN, 2Tokyo women’s medical university, Tokyo,
JAPAN.
594
The Influence of Suspended and Aligned Fibrous
Topographical Environment on Mesenchymal Stem
Cell Behavior
T. L. Popielarczyk1, J. G. Barrett2, A. S. Nain3; 1Marion
duPont Scott Equine Medical Center, VirginiaMaryland Regional College of Veterinary Medicine,
Leesburg, VA, 2Department of Large Animal Clinical
Sciences, Virginia-Maryland Regional College of
Veterinary Medicine, Leesburg, VA, 3Department of
Mechanical Engineering, Virginia Tech, Blacksburg, VA.
Xenotransplantation Model Of Human
Spermatogonial Stem Cells (SSCs) To Cynomolgus
Monkeys’ Testes- A Feasibility Study
H. Sadri-Ardekani1, D. Sohutskay1, J. M. Cline2, A.
Atala1; 1Wake Forest Institute for Regenerative
Medicine (WFIRM), Wake Forest School of Medicine,
Winston Salem, NC, 2Wake Forest Primate Center
(WFPC), Friedberg Campus, Wake Forest School of
Medicine, Winston Salem, NC.
Native Tissue-Specific ECMs Exhibit Distinct
Mechanical Properties Affecting the Fate of hMSCs
M. Marinkovic1, T. Block1, R. Rakian2, D. Dean1, M.
Reilly3, X. Chen1; 1Comprehensive Dentistry, University
of Texas Health Science Center at San Antonio, San
Antonio, TX, 2Physiology, University of Texas Health
Science Center at San Antonio, San Antonio, TX,
3
Biomedical Engineering, University of Texas at San
Antonio, San Antonio, TX.
Establishing Guidelines for Obtaining Optimal
Cell Sources to use in Tendon Tissue Engineering
Strategies
A. I. Gonçalves, M. T. Rodrigues, R. L. Reis, M. E.
Gomes; 3B’s Research Group, Guimarães, PORTUGAL.
TERMIS–AM • 2014
595
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597
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Magnetic Labeling of BM-MSC-Derived SMCs
Maintains their Pro-Elastogenic Trophic Effects on
Aneurysmal SMCs
G. Swaminathan1, B. Sivaraman1, I. Stoilov2, M. Shah3,
G. Zhang3, R. P. Mecham2, A. Ramamurthi1; 1BME,
Cleveland Clinic, Cleveland, OH, 2Cell Biology and
Physiology, Washington University, St. Louis, MO,
3
BME, The University of Akron, Akron, OH.
Comparison of Trypsin and Pronase Modification of
Stem Cells in Cell Homing to Injured Tissue.
S. J. Kim1, P. A. Tebebi2, S. R. Burks1, R. Williams1,
B. A. Nguyen1, J. A. Frank1; 1Radiology and
Imaging Sciences, NIH, Bethesda, MD, 2Biomedical
Engineering, The Catholic University of America,
Washington, DC.
Mesenchymal Stem Cell Homing to Kidneys is
Inhibited by Disrupting Interleukin 1 alpha, Tumor
Necrosis Factor alpha, or Cyclooxygenase-2
Signaling
S. Burks, B. Nguyen, S. Kim, J. Frank; NIH Clinical
Center, Bethesda, MD.
Role of Macrophage Migration Inhibitory Factor in
Regulation of Senescence of Human Mesenchymal
Stem Cells in Hypoxic Culture
S. Palumbo, W. Li; Orthopedics, University of
Wisconsin-Madison, Madison, WI.
Myogenic Differentiated Mesenchymal Stem Cells
Improve Muscle Function In a Murine Model of
X-linked Myotubular Myopathy
H. Lim1, D. Eckman2, S. Joo1, J. Jackson1, A. Atala1,
J. Yoo1; 1Wake Forest Institute for Regenerative
Medicine (WFIRM), Wake Forest University School
of Medicine, Winston Salem, NC, 2College of Health
Sciences, Midwestern University, Glendale, AZ.
Adipose Derived Stem Cell therapy for skeletal
muscle regeneration
A. Gorecka1, L. Bruegger1, D. Eberli2, D. Candinas1;
1
Department of Clinical Research, University of Bern,
Bern, SWITZERLAND, 2Department of Urology and
Zurich Center for Integrative Human Physiology
(ZIHP), University of Zurich, Zurich, SWITZERLAND.
Measurement Assurance in Stem Cell
Characterization: Quantitative Comparison of Cell
Enumeration Techniques
S. Lund2, S. Sarkar1, R. Vyzasatya3, P. Vanguri3,
M. Halter1, J. T. Elliott1, S. Lin-Gibson1, A. L. Plant1;
1
Biosystems and Biomaterials Division, National
Institute of Standards and Technology, Gaithersburg,
MD, 2Statistical Engineering Division, National
Institute of Standards and Technology, Gaithersburg,
MD, 3Cell Therapy, Lonza, Walkersville, MD.
POSTER PRESENTATIONS
599
600
601
602
603
604
606
Comparison of Bone Marrow Aspiration Site Options
in the Spanish Boer Goat - Development of a Caprine
Tibial Defect Model
C. Boehm1, V. Luangphakdy1, H. Pan1, A. Nicholson2, J.
E. Bechtold3, C. S. Carlson4, E. Pluhar5, G. F. Muschler1;
1
Biomedical Engineering, Cleveland Clinic, Cleveland,
OH, 2Department of Large Animal Surgery, University
of Minnesota, Saint Paul, MN, 3Ortopaedic Surgery
& Biomedical Engineering, University of Minnesota,
Minneapolis, MN, 4Veterinary Population Medicine,
University of Minnesota, Saint Paul, MN, 5Veterinary
Clinical Sciences, University of Minnesota, Saint Paul, MN.
Muscle Precursor Cells for the Treatment of Fecal
Incontinence
L. Bruegger1, A. Gorecka1, R. Inglin1, D. Candinas1, D.
Eberli2; 1Department of Clinical Research, University
of Bern, Bern, SWITZERLAND, 2Department of
Urology and Zurich Center for Integrative Human
Physiology (ZIHP), University of Zurich, Zurich,
SWITZERLAND.
607
608
Optimizing Glial Differentiation of Human
Mesenchymal Stem Cells under Physiologically Low
Oxygen Tension
Z. Qian, F. Zhao; Biomedical Engineering, Michigan
Technological University, Houghton, MI.
Mechanisms Of Adipose Stem Cell Differentiation: Is
The Primary Cilium A Novel Therapeutic Target?
J. Bodle1, M. S. Hamouda2, S. H. Bernacki1, E.
G. Loboa1; 1Joint Department of Biomedical
Engineering, North Carolina State University, Raleigh,
NC, 2Biomedical Engineering, North Carolina State
University, Raleigh, NC.
Combinatorial Fibronectin and Laminin Signaling
Promote Highly Efficient Cardiac Differentiation of
Human Embryonic Stem Cells
S. Sa, L. Wong, K. E. McCloskey; Bioengineering,
University of California, Merced, Merced, CA.
Effect of Polarized Macrophages on Human Stem
Cell Derived Cardiomyocytes
D. O. Freytes, E. A. Wrona, I. Pallotta; New York Stem
Cell Foundation Research Institute, New York, NY.
Extracellular Calcium Controls Differentiation in
Human and Porcine Adipose Derived Stem Cells:
A Novel Approach for Osteochondral Tissue
Engineering
L. Mellor1, J. Williams, II1, F. Guilak2, S. Koh3, J.
Piedrahita3, E. G. Loboa1; 1Joint Department of
Biomedical Engineering, North Carolina State
University, Raleigh, NC, 2Department of Orthopaedic
Surgery, Duke University, Durham, NC, 3College of
Veterinary Medicine, North Carolina State University,
Raleigh, NC.
609
Osteochondral Defect Repair Using Bilayered
Hydrogels Encapsulating Both Chondrogenically
and Osteogenically Pre-differentiated Mesenchymal
Stem Cells in a Rabbit Model
J. Lam1, S. Lu1, E. J. Lee1, J. E. Trachtenberg1, V. V.
Meretoja1, R. L. Dahlin1, J. van den Beucken2, Y.
Tabata3, M. E. Wong4, J. A. Jansen2, A. G. Mikos1, F.
K. Kasper1; 1Rice University, Houston, TX, 2Radboud
umc, Nijmegen, NETHERLANDS, 3Institute for
Frontier Medical Sciences, Kyoto University, Kyoto,
JAPAN, 4The University of Texas School of Dentistry,
Houston, TX.
Mesenchymal Stem Cell Acts As Antioxidant And
Elevates Reduced Glutathione Levels In A Murine
Model Dss-induced Colitis
F. d. Gonçalves1, M. Grings2, N. Schneider1, F. O.
Pinto3, T. N. Garcez4, G. Leipnitz5, A. H. PAZ6;
1
b.Graduate Program in Gastroenterology and
Hepatology Sciences, Porto Alegre Universidade
Federal do Rio Grande do Sul, Rio Grande do Sul,
Brazil, PORTO ALEGRE, BRAZIL, 2Biochemistry
Department, FEDERAL UNIVERSITY OF RIO
GRANDE DO SUL- PORTO ALEGRE- BRAZIL,
PORTO ALEGRE, BRAZIL, 3CLINICAL HOSPITAL
OF PORTO ALEGRE- RESEARCH CENTEREMBRIOLOGY AND CELL DIFFERENTIATION
LABORATORY- FEDERAL UNIVERSITY OF RIO
GRANDE DO SUL- PORTO ALEGRE- BRAZIL,
PORTO ALEGRE, BRAZIL, 4CLINICAL HOSPITAL OF
PORTO ALEGRE- RESEARCH CENTER- - PORTO
ALEGRE- BRAZIL, PORTO ALEGRE, BRAZIL,
5
Biochemistry Departmentio, FEDERAL UNIVERSITY
OF RIO GRANDE DO SUL- PORTO ALEGRE- BRAZIL,
PORTO ALEGRE, BRAZIL, 6MORPHOLOGICAL
SCIENCES, CLINICAL HOSPITAL OF PORTO
ALEGRE- RESEARCH CENTER- EMBRIOLOGY AND
CELL DIFFERENTIATION LABORATORY- FEDERAL
UNIVERSITY OF RIO GRANDE DO SUL- PORTO
ALEGRE- BRAZIL, PORTO ALEGRE, BRAZIL.
SDF-1β Over-Expressing BMSCs Relative to Empty
Vector BMSCs Enhance Healing of Critical-Size
Mouse Calvarial Defects in a BMP-2 Co-Therapy
model
S. A. Herberg1, A. Aguilar-Perez2, S. PeriyasamyThandavan1, R. N. Howie1, M. Elsalanty3, X. Shi4, M. M.
Hamrick1, C. M. Isales4, J. Cray5, W. D. Hill, II1; 1Cellular
Biology & Anatomy, Georgia Regents University,
Augusta, GA, 2Cellular and Molecular Biology,
Universidad Central del Caribe, Bayamon, PR, 3Oral
Biology, Georgia Regents University, Augusta, GA,
4
Orthopaedic Surgery, Georgia Regents University,
Augusta, GA, 5Department of Oral Health Sciences,
Medical University of South Carolina, Charleston, SC.
www.termis.org/am2014
47
610
611
612
613
614
615
616
48
Linear Regression Analysis of Combinatorial
Parameters for Endothelial Cell Fate Optimization
D. E. Glaser1, W. S. Turner1, A. B. Burns2, K. E.
McCloskey1; 1School of Engineering, University of
California, Merced, Merced, CA, 2School of Natural
Sciences, University of California, Merced, Merced, CA.
617
619
Regenerative Capacity of Cardiac Progenitor Cells
is Dependent on Mechanical Strain and Matrix
Composition
K. M. French1, M. J. Fierro1, S. K. Ghosh-Choudhary1,
T. D. Johnson2, K. L. Christman2, M. E. Davis1;
1
Biomedical Engineering, Emory University, Atlanta,
GA, 2Bioengineering, University of California, San
Diego, La Jolla, CA.
Approaching Cartilage Tissue Engineering through
Human Umbilical Cord-Derived Mesenchymal
Stromal Cellular Aggregates
B. Sridharan1, A. T. Hwu2, S. Lin2, M. S. Detamore1;
1
Bioengineering, University of Kansas, Lawrence,
KS, 2Chemical Engineering, University of Kansas,
Lawrence, KS.
Comparison of Two Scaffolds for Human Adipose
Mesenchymal Stem Cells Culture.
R. Sánchez, Sr.1, A. Brena-Molina1, M. Valentin2, Y.
Melgarejo-Ramírez1, L. Tamay de Dios1, R. GómezGarcía2, M. Reyes-Frias3, M. Maria3, R. Lourdes1, D.
Garciadiego1, C. Ibarra1, C. Velasquillo Martinez1;
1
Biotechnology, National Institute of Rehabilitation,
Mexico City, MEXICO, 2Tissue Engineering, National
Institute of Rehabilitation, Mexico City, MEXICO,
3
Biotechnology, Instituto Nacional de Investigaciones
Nucleares, Mexico City, MEXICO.
Hydrogel Microspheres For Spatiotemporally
Controlled Delivery Of Sirna to stem cells
A. McMillan, M. K. Nguyen, C. Z. Mosher, E. Alsberg;
Case Western Reserve University, Cleveland, OH.
Comparison of Two Sources of Stem Cells For
Cartilage Tissue Engineering.
R. Gomez, Sr.1, E. Camacho2, C. Velasquillo1, M. Maria3,
C. Ibarra1; 1Tissue Engineering, National Institute of
Rehabilitation, Mexico City, MEXICO, 2Veterinary
Medicine, UNAM, Mexico City, MEXICO, 3Equine
Medicine, Universidad Nacional Autónoma de
México, Mexico City, MEXICO.
Building 3D Tissue Niches for Differentiating Human
Pluripotent Stem Cells into Pancreatic Endoderm
K. Ye, W. Wang, S. Jin; Biomedical, State University
of New York at Binghamton, Binghamton, NY.
TERMIS–AM • 2014
621
622
624
625
Modulation Of Pulmonary Differentiation Of Murine
Embryonic Stem Cells Using Physical Cues
S. Karamil, P. Lelkes; Bioengineering, Temple
University, Philadelphia, PA.
Cells Sheets of Adipose Tissue Stromal Vascular
Fraction as Vascularization Units for Tissue
Engineering and Regenerative Medicine
M. Costa, M. T. Cerqueira, D. B. Rodrigues, T. C.
Santos, A. P. Marques, R. P. Pirraco, R. L. Reis; 3B’s
Research Group - Biomaterials, Biodegradables and
Biomimetics, University of Minho, Headquarters
of the European Institute of Excellence on Tissue
Engineering and Regenerative Medicine; ICVS/3B’s
- PT Government Associate Laboratory, Guimarães,
PORTUGAL.
Hydrogel Microencapsulation of Mouse Embryonic
Stem Cells for Enhanced Proliferation and
Differentiation of Definitive Endoderm in Modeled
Microgravity
E. S. Guimaraes1, C. T. Stabler2, L. C. Júnior2, S. Lecht2,
R. M. Garcia1, P. I. Lelkes2; 1Department of Biology,
Federal University of Juiz de Fora, Juiz de Fora,
BRAZIL, 2Department of Bioengineering, Temple
University, Philadelphia, PA.
PDGF-BB Enhances Osteogenesis in Adiposederived but not Marrow-derived Mesenchymal Stem
Cells
B. P. Hung1, D. L. Hutton1, K. L. Kozielski1, C. J.
Bishop1, B. Naved2, J. J. Green1, A. H. Dorafshar2, W.
L. Grayson1; 1Translational Tissue Engineering Center,
Johns Hopkins University, Baltimore, MD, 2Johns
Hopkins Hospital, Baltimore, MD.
Amniotic Fluid Stem Cells And Chronic Kidney
Disease
S. Sedrakyan1, S. Da Sacco1, A. Petrosyan1, K.
Lemley2, R. De Filippo1, L. Perin1; 1Urology, Children’s
Hospital Los Angeles, Los Angeles, CA, 2Nephrology,
Children’s Hospital Los Angeles, Los Angeles, CA.
Enhanced Oxygen Supply to Immunoisolated Islets
In vivo Enables their Viability and Function at
Tissue Like Densities
K. K. Papas1, L. Steyn1, M. Davies1, T. Loudovaris2,
S. Limesand1, L. Tempelman3, E. S. Avgoustiniatos1;
1
Surgery, University of Arizona, Tucson, Tucson, AZ,
2
St Vincent’s Institute, Victoria, AUSTRALIA, 3Giner
Inc, Newton, MA.
POSTER PRESENTATIONS
626
627
628
629
630
631
Re-endothelialization of Acellular Liver Scaffolds
for Whole Organ Engineering
I. Ko, C. J. Smith, P. Li, A. Peloso, A. Dhal, C. Clouse,
W. Zhao, T. Shupe, A. Atala, S. Soker, J. J. Yoo; Wake
Forest Institute for Regenerative Medcine, Winston
Salem, NC.
Re-engineering the 3D Pancreatic Niche - Coculturing Differentiating Human Embryonic Stem
Cells with Endothelial Cells in Decellularized
Pancreatic Scaffold
S. Goh1, S. Bertera2, I. Banerjee1; 1Bioengineering,
University of Pittsburgh, Pittsburgh, PA, 2Division
of Immunogenetics, University of Pittsburgh,
Pittsburgh, PA.
Co-cultivation of Mesenchymal Stem Cells and Skin
Keratinocytes on Electrospun Scaffolds
D. Steffens1, B. T. Santi2, D. P. Luco3, M. B. Mathor3,
P. Pranke4; 1Hematology and Stem Cell Laboratory,
Faculty of Pharmacy (UFRGS); Post-graduation
Program in Physiology (UFRGS), Porto Alegre,
BRAZIL, 2Hematology and Stem Cell Laboratory,
Faculty of Pharmacy, UFRGS, Porto Alegre, BRAZIL,
3
Institute of Nuclear Energy Research, São Paulo,
BRAZIL, 4Hematology and Stem Cell Laboratory,
Faculty of Pharmacy (UFRGS); Post-graduation
Program in Physiology (UFRGS); Stem Cell Research
Institute; Brazil, Porto Alegre, BRAZIL.
Repopulation of Primary Renal Cells for Whole
Organ Engineering: Functional Evaluations
M. Abolbashari, M. Lee, S. Agcaoili, J. Huling, C. J.
Smith, T. Aboushwareb, I. Ko, A. Atala, J. J. Yoo; Wake
Forest Institute for Regenerative Medcine, Winston
Salem, NC.
D Context Regulates Hypoxic Response and
Angiogenesis in Engineered Models of the Tumor
Microenvironment
P. DelNero1, S. Verbridge2, M. Lane3, P. Rabbany3, B.
Kwee1, Y. Zheng4, A. Stroock1, C. Fischbach1; 1Cornell
University, Ithaca, NY, 2Virginia Tech-Wake Forest
University, Blacksburg, VA, 3Weill Cornell Medical
School, New York, NY, 4University of Washington,
Seattle, WA.
3
632
633
634
635
637
638
639
Engineering the Bone Metastatic Prostate Cancer
Microenvironment Using a Three-Dimensional
Hyaluronan-Based Hydrogel System
E. L. Fong1, D. A. Harrington2, A. G. Mikos1, M. C.
Farach-Carson2; 1Bioengineering, Rice University,
Houston, TX, 2Biochemistry and Cell Biology, Rice
University, Houston, TX.
Modeling The Colon-tumor Microenvironment Using
Multicellular Hydrogel Strata
M. Devarasetty, A. Skardal, S. Soker; Biomedical
Engineering, Wake Forest Institute for Regenerative
Medicine, Winston-Salem, NC.
Synergetic Effect of Cold Atmospheric Plasma and
Nanospheres Drug Delivery on Inhibiting Breast
Cancer Cell Growth
W. Zhu, S. Lee, M. Keidar, L. Zhang; The George
Washington University, Washington, DC.
Mechanisms of Glioma Cell Migration within 3D
Biomimetic Microenvironment
C. R. Kothapalli, A. Powell; Chemical & Biomedical
Engineering, Cleveland State University, Cleveland, OH.
Three Dimensional Microphysiologic Liver Model for
Toxicity Testing
L. Miller, L. Marshall, J. Berry; University of Alabama
at Birmingham, Birmingham, AL.
Novel Site-Specific Immunosuppression Strategies
for Vascularized Composite Allotransplantation
F. Feturi, M. Weinstock, Y. Li, J. Schnider, J. Plock, V.
Gorantla, W. Zhang, M. Solari, R. Venkataramanan;
University of Pittsburgh, Pittsburgh, PA.
Magnesium Scaffold Coated β-tricalcium Phosphate
Induced the Osteogenic Differentiation of Bone
Marrow Mesenchymal Stem Cells
X. Mao1, Z. Chen2, L. Tan3, Y. Xiao2; 1Department of
Operative Dentistry and Endodontics, Sun Yat-sen
University, Guangzhou, CHINA, 2Institute of Health
and Biomedical Innovation, Queensland University of
Technology, Brisbane, AUSTRALIA, 3Institute of Metal
Research, Chinese Academy of Sciences, Shenyang,
CHINA.
D Printed Biomimetic Bone Model with Micro
Network and Nano Hydroxyapatite for Breast
Cancer Metastasis Study
B. B. Holmes, L. G. Zhang; MAE, The George
Washington University, Washington, DC.
3
www.termis.org/am2014
49
640
641
642
643
644
645
50
Proteomic Study Points Towards Rho-GDI
2
-connected Signalling During Skin Graft
Revascularization
A. Hegglin1, S. Mikkat2, M. Russ2, M. Kreutzer2, B.
Vollmar3, P. Giovanoli1, M. O. Glocker2, N. Lindenblatt1;
1
Surgery Research, University Zürich- University
Hospital, Zürich, SWITZERLAND, 2Proteome
Center Rostock, Rostock, GERMANY, 3Institute
for Experimental Surgery, University of Rostock,
Rostock, GERMANY.
646
647
Segmentation of Large Numbers of 3D Cells on
Different Scaffolds
M. Simon, D. Juba, P. Baker, C. G. Simon, Jr, M. Brady,
P. Bajcsy; ITL, NIST, Gaithersburg, MD.
Integration of Semisynthetic Biomaterials and
Nanofabrication to Optimize 3D Liver Culture
K. Renggli1, M. S. Raredon1, P. T. Hammond2,
B. Imperiali3, L. G. Griffith1; 1Department of
Biological Engineering, Massachusetts Institute
of Technology, Cambridge, MA, 2Department of
Chemical Engineering, Massachusetts Institute of
Technology, Cambridge, MA, 3Department of Biology,
Massachusetts Institute of Technology, Cambridge, MA.
Pluripotent Stem Cell Culture On Biomaterials
Having Nanosegments With Optimal Elasticity
A. Higuchi1, S. Kumar2, M. A. Munusamy3, A. A.
Alarfaj3, A. Higuchi4; 1Department of Chemical &
Materials Engineering,, National Central University,
Jhong-Li, TAIWAN, 2Department of Medical
Microbiology and Parasitology, Universities Putra
Malaysia, Selangor, MALAYSIA, 3Department of
Botany and Microbiology, King Saud University,
Riyadh, SAUDI ARABIA, 4Riken, Wako, JAPAN.
Three-dimensional Assembly of Endometrial Tissue
In Vitro
G. Kuramoto1, S. Takagi2, K. Ishitani3, T. Shimizu2, T.
Okano2, H. Matsui3; 1Institute of Advanced Biomedical
Engineering and Science and Department of
Obstetrics and Gynecology, Tokyo Women’s Medical
University, Tokyo, JAPAN, 2Institute of Advanced
Biomedical Engineering and Science, Tokyo Women’s
Medical University, Tokyo, JAPAN, 3Department of
Obstetrics and Gynecology, Tokyo Women’s Medical
University, Tokyo, JAPAN.
DiameterJ: An Open Source Nanofiber Diameter
Measurement Tool
N. A. Hotaling1, K. Bharti2, H. Kriel3, C. G. Simon, Jr.1;
1
Biosystems and Biomaterials, National Institute of
Standards and Technology, Gaithersburg, MD, 2Ocular
and Stem Cell Translational Research, National
Institute of Health, Bethesda, MD, 3The Stellenbosch
Nanofiber Company (Pty) Ltd, Cape Town, SOUTH
AFRICA.
TERMIS–AM • 2014
648
649
650
651
652
Morphological Characteristics of a ThreeDimensional Multi-Phasic Tissue Engineered
Temporomandibular Joint Construct
J. D. Lee1, J. I. Becker1, S. D. Kapila2, L. M. Larkin1;
1
Molecular & Integrative Physiology, University of
Michigan, Ann Arbor, MI, 2Orthodontics and Pediatric
Dentistry, University of Michigan, Ann Arbor, MI.
Culture Surface Design to Direct Commitment
of Human Mesenchymal Stem Cells to Myogenic
Lineage
F. D. Ayuningtyas1, Y. Ogawa2, M. Kim2, A. Barlian1,
M. Kino-oka2; 1Biotechnology Master Program,
School of Life Sciences and Technology, Institute
of Technology Bandung, Bandung, INDONESIA,
2
Biotechnology, Osaka University, Osaka, JAPAN.
Optimal Amount Of Basic Fibroblast Growth
Factor (b-fgf) In Gelatin Sponges Incorporating
β-tricalcium Phosphate (tcp) With Chondrocytes
M. Komura1, H. Komura2, Y. Otani2, Y. Tabata3; 1Saitama
Medical University, Saitama prefecture, JAPAN,
2
Tokyo University, Tokyo, JAPAN, 34.Department of
Biomaterials, Kyoto University, Kyoto, JAPAN.
Three-dimensional Micro-Bioscaffolds Enhance
Protein Expression in Induced PluripotentStem CellDerived Hepatocytes
B. Wang1, A. Jakus1, P. Baptista2, S. Soker2, A. SotoGutierrez3, M. Abecassis1, R. Shah1, J. Wertheim1;
1
Northwestern University, chicago, IL, 2Wake Forest
University School of Medicine, Winston-Salem, NC,
3
University of Pittsburgh, Pittsburgh, PA.
Biomimetic Hyaluronic Acid Delivery And
Lubrication On Tissue And Biomaterial Surfaces
A. Singh, M. Corvelli, J. Elisseeff; Biomedical
Engineering, Johns Hopkins University, Baltimore,
MD.
Isolation and Characterization of Ovine Cd90+ Cells
Derived from Mobilized Peripheral Blood
C. Landa-Solís, C. Ortega-Sánchez., J. GranadosMontiel, A. Olivos-Meza., C. Pineda-Villaseñor, E.
Hazan-Lasri, M. Velasquillo-Martínez, J. IbarraPonce de León; NATIONAL INSTITUTE OF
REHABILITATION, MEXICO, MEXICO.
Development Of A Cell Sheet Co-cultured With
Endothelial Cells And Smooth Muscle Cells Using
Thermosensitive Hydrogels For Therapeutic
Angiogenesis
H. Shin, S. Bak, Y. Lee, T. Ahmad, J. Lee;
Bioengineering, Hanyang University, Seoul, KOREA,
REPUBLIC OF.
POSTER PRESENTATIONS
653
654
655
656
657
658
659
Fluorescent Detection and Quantification of
Protein Released During Electrospun Nanofiber
Degradation
K. L. Lee1, G. Moore2, J. A. Cooper1; 1Biomedical
Engineering, Rensselaer Polytechnic Institute, Troy,
NY, 2Mechanical Engineering, University of South
Alabama, Mobile, AL.
Comparison of the Homology and Functionality of
the Pluripotent Stem Cells derived from the Human
and Sheep Peripheral Mobilized Blood.
C. Landa-Solis1, A. Olivos-Meza2, C. Ortega-Sánchez2,
J. Granados-Montiel2, C. Velasquillo-Martinez2,
C. Ibarra2, C. Pineda2; 1Tissue Engineering and
Regenerative Medicine Laboratory, National Institute
of Rehabilitation, Mexico city, MEXICO, 2Orthopedic
Sports Medicine and Arthroscopy, National Institute
of Rehabilitation, Mexico city, MEXICO.
Evaluation of the Viability And Chondrogenic
Capability of Cadaveric Chondrocytes For Clinical
Application In Cartilage Repair.
A. Olivos-Meza, C. Ortega-Sánchez, V. MartinezLopez, E. Alvarez-Lara, R. Pichardo-Bahena, C.
Landa-Solis, J. Granados-Montiel, C. VelasquilloMartinez, C. Ibarra, C. Pineda; Orthopedic Sports
Medicine and Arthroscopy, National Institute of
Rehabilitation, Mexico city, MEXICO.
Impact of Collagen-Incorporated Electrospun
Conduits on Graft Mechanics and Recruited
Peritoneal Cell Phenotype
K. Birthare1, C. Gross-Jones2, J. R. Brenner3, C. A.
Bashur1; 1Biomedical Engineering, Florida Institute of
Technology, Melbourne, FL, 2Mechanical Engineering,
Florida Institute of Technology, Melbourne,
FL, 3Chemical Engineering, Florida Institute of
Technology, Melbourne, FL.
660
661
662
663
664
665
Tissue Hypoxia And Murray’s Law Govern Optimal
Control Of Neovascular Growth And Remodeling
J. Boerckel; Aerospace and Mechanical Engineering,
University of Notre Dame, Notre Dame, IN.
In Vivo Comparison Of Structural Polymer And
Non-structural Hydrogel Scaffolds For Bone Tissue
Engineering
J. Boerckel1, A. M. McDermott1, A. S. Lin2, R. E.
Guldberg3; 1Aerospace and Mechanical Engineering,
University of Notre Dame, Notre Dame, IN,
2
Mechanical Engineering, Georgia Institute of
Technology, Atlanta, GA, 3Mechanical Engineering,
Georgia Institute of Technology, Georgia Institute of
Technology, GA.
666
667
Hypoxic Conditioned Medium Of Mesenchymal
Stem Cells Enhanced Bone Regeneration In Rat
Calvarial Bone Defects Through Regulation Of Pdgf
Targeted-microran-206
S. Park; Incheon St. Mary’s Hospital, Incheon, KOREA,
REPUBLIC OF.
Using Surface Enhanced Raman Spectroscopy to
Assess the Calcification Potential of Engineered
Vascular Grafts
K. R. Kerney, N. Roki, M. B. Fenn, C. A. Bashur;
Biomedical Engineering, Florida Institute of
Technology, Melbourne, FL.
Enhanced Fibrin Gel for Cellular Therapy
l. brewster1, S. Robinson2, A. Douglas3, I. Copland4,
T. Barker3; 1Surgery, Emory, decatur, GA, 2Surgery,
Michigan, ann arbor, MI, 3Biomedical engineering,
Georgia Institute of Technology, atlanta, GA,
4
Hematology and Medical Oncology, Emory, atlanta, GA.
Analysis and Sorting of Large Stem Cell Aggregates
Based on Intrinsic Biomarkers
B. Ogle1, D. Buschke2; 1Biomedical Engineering,
University of Minnesota-Twin Cities, Minneapolis,
MN, 2Biomedical Engineering, SONY Biotechnology
(Formerly University of Wisconsin-Madison),
Madison, WI.
Synthetic Cell Penetrating Peptides for Drug
Delivery and Stem Cell Applications
G. Jin, F. Ghasemi Tahrir, W. Ma, W. H. Suh;
Bioengineering, Temple University, Philadelphia, PA.
Evaluating Brushing Device to Deposit Human Bone
Marrow Derived Stromal Cells (hBMSCs) for Tissue
Engineering Applications
C. Maczka1, D. Estridge2, G. Kaufman3, W. Tutak3;
1
University of Maryland, Baltimore, MD, 2Montgomery
Community College, Germantown, MD, 3American
Dental Association Foundation. Dr. Volpe Research
Center, Gaithersburg, MD.
Neuronal Differentiation of Human Neural Stem Cell
Achieved by Electrostimulation
F. Ghasemi Tahrir, G. Jin, W. Ma, W. H. Suh;
Bioengineering, Temple University, Philadelphia, PA.
Poly(glycerol sebacate) as an Elastomeric Coating
for Biomedical Textiles
J. J. Harris, C. M. Smoot; Research, Secant Medical,
Inc., Perkasie, PA.
Bioprinting de novo Cartilage from Particulated
Cartilage ECM-Based Bioinks
M. Kesti, M. Zenobi-Wong; Health Sciences and
Technology, ETH Zurich, Zurich, SWITZERLAND.
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668
669
670
52
Material Properties Vary among Raw Material
Bladder Sources for ECM-based Products
J. Miller1, H. Charapp2, L. Frazier1, D. Price1, B.
Young1, N. Gheewala1, T. W. Gilbert1; 1R&D, ACell,
Inc, Columbia, MD, 2Department of Biomedical
Engineering, Penn State University, University Park,
PA.
Airbrushed Poly-DL-lactic Acid Nanofibers Coated
with Collagen Type I and Fibrinogen Proteins
Enhance Human Bone Marrow Stromal and
Umbilical Vein Endothelial Cell Attachment
C. Maczka1, S. Bodhak2, J. J. Kim3, W. Tutak3;
1
University of Maryland, Baltimore, MD, 2Biomaterials,
National Institute of Standards and Technology,
Gaithersburg, MD, 3Tissue Engineering, American
Dental Association Foundation, Gaithersburg, MD.
Combinatorial Cassette For High-throughput
Screening Of Osteogenesis
S. Bodhak1, L. F. Diaz2, S. A. Kuznetsov2, T. Kilts2, M.
F. Young2, S. Lin-Gibson1, P. G. Robey2, C. G. Simon,
Jr.1; 1Biomaterials Group, Biosystems & Biomaterials
Division, National Institute of Standards and
Technology, Gaithersburg, MD, 2National Institute of
Dental & Craniofacial Research, National Institutes of
Health, Bethesda, MD.
TERMIS–AM • 2014
671
672
Phosphorylation contributes to flexibility and
secondary structure of Dentin Phosphoprotein
Peptides.
E. Villarreal1, A. Gericke2, A. Boskey1; 1Mineralized
Tissue Laboratory, Hospital for Special Surgery,
NY, NY, 2Department Of Chemistry & Biochemistry,
Worcester Polytechnic Institute, Worcester, MA.
Bilayered Micro-nanofibrous Scaffold for Skin
Tissue Engineering
P. PAL, P. K. Srivas, P. Dadheech, B. Das, S. Dhara;
School of Medical Science and Technology, Indian
Institute of Technology, Kharagpur, Kharagpur, INDIA.
FINAL PROGRAM
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53
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TERMIS–AM • 2014
Now accepting
submissions
EDITOR-IN-CHIEF
David L. Kaplan
Tufts University
Research at the
intersection of
chemistry, biology,
materials science,
and engineering>>>
ACS Publications is pleased to introduce
ACS Biomaterials Science & Engineering,
a new journal formed to address the
rapid growth, fueled by the biomedical
and biotechnology industries.
Manuscripts will cover a broad spectrum
of topics including:
> Modeling and informatics tools
for biomaterials
> New biomaterials, bioinspired and
biomimetic approaches to biomaterials
> Biomaterial interfaces, health risk studies
studies of biomaterial
> Bioelectronics, bioMEMS, biomaterials
based devices and prosthetics
> Regenerative medicine, biomaterial
technology for tissues, genetic designs
and bioengineering
pubs.acs.org/biomaterials
www.termis.org/am2014