Modular Microscopes
Cerna Series Microscopy Systems
The Cerna Series is a modular microscopy platform for a wide range of experiments
and applications. Designed to let you configure a system to your exact experimental
requirements, it is especially useful for setups that require a large workspace beneath
the objective or wide-angle access to the objective and other optical components.
Our Cerna rigs are complete systems that fully support conventional microscopy
techniques, including epi-fluorescence, DIC, Dodt contrast, confocal laser scanning,
and intrinsic signal imaging. The modular design allows them to be easily modified to
better suit specific experimental needs.
Alternatively, users can choose to start from one of eight pre-configured optical
paths and add components of their choosing, or, for the most flexibility, pick from the
Cerna Series’ large selection of interchangeable modules and build a system from
the ground up. Interfaces for cage and lens tube systems and optional breadboards
allow custom components to be integrated with Cerna Systems.
Modular Imaging Systems
Plug and Play: Cerna Rigs
Cerna Rigs provide complete, customizable imaging solutions for
the life sciences. Every system is based on one of Thorlabs' slim
Cerna Microscope Bodies, minimizing the footprint on the optical
table and maximizing the space beneath the objective. The rigs are
completed with motorized sample stages, cameras, light sources,
50 µm
Brightfield Image of a Buttercup Root
micromanipulators, and other accessories carefully selected by our
applications engineers to address specific imaging needs:
uWidefield
Imaging
uElectrophysiology
uConfocal
uIntrinsic
Laser Scanning Microscopy
Imaging
50 µm
Combined DIC and Widefield Fluorescence Image of a Mouse
Kidney Tagged with GFP
Since the Cerna System is completely modular, these systems are
100 µm
just a sample of what the Cerna line can offer. Our applications
engineers can draw from the large selection of Cerna components
and Thorlabs' extensive optomechanics catalog to modify each rig
for the researcher's needs.
Explore several sample rig configurations in the following pages
to learn more about our systems. If you have specific imaging
requirements, our imaging sales team is available at
ImagingSales@thorlabs.com to provide more information on
what the Cerna line can offer to support your experiment.
Cerna CRE1004 Electrophysiology Rig
This Cerna Rig supports DIC imaging.
It also includes micromanipulators,
trinoculars for viewing erect images
of the sample, and translators for the
sample platform and microscope.
Objectives (not included) are
available from Thorlabs’
selection of Cerna
accessories.
Confocal Image Showing a Fly Eye
Complete Optical Paths: Cerna Microscope Bodies
CM1003
This Cerna Microscope Body
includes a single-cube epiilluminator and transmitted light
module for brightfield imaging.
For researchers who desire to add their own components such as
cameras and light sources, Thorlabs’ line of Cerna Microscope
Bodies are pre-configured optical paths. These microscope
bodies include the complete optical path, with components such
as epi-illumination paths, eye pieces, objective holders, and transmitted
illumination modules.
Cameras, light sources, filters, objectives, and more are available from
Thorlabs’ extensive catalog of Cerna accessories and optomechanical
components, providing a path to customize the microscope body for
specific applications or add capabilities as experimental needs change.
Fast-Frame-Rate
Scientific Camera
DIC Elements
Build Your Own Microscope: Cerna Components
Our rigs and microscopes are constructed from a variety of interoperable modules to
leave open a path for future upgrades as experimental needs change. The system also
supports users who wish to build their own microscopes from the ground up utilizing our
selection of Cerna modules. In addition to standard microscope modules, the Cerna line
includes interfaces designed to directly integrate Thorlabs’ extensive catalog of optical
and mechanical components for maximum flexibility and customizability.
User-Customized Cerna
Microscope Configured for
DIC and Epi-Fluorescence
LED for EpiIllumination
0.78 NA Condenser
Breadboard for
Custom Epi-Illumination
Visible Transmitted
Illumination Kit
Widefield Imaging Rigs
Cerna Widefield Imaging Rigs are designed to serve as workhorses for basic, everyday
Applications
imaging requirements, such as assessing and verifying sample preparations.
u Verify
Large, Open Working Space
and Assess Sample
Preparations
The 400 mm tall microscope body and 7.74" (195.6 mm) throat depth create a large
u Visualize
working volume beneath the objective, which provides ample space for large-range
Morphologies in
Thick and Thin Unlabeled
adjustments of the specimen position and wide-angle access to the objective and the rest
Tissue Samples
of the optical path.
u Observe
Identify Markers and Structural Features using Epi-Fluorescence, DIC,
and/or Dodt Contrast Imaging
Fast Dynamics in
Microfluidic Chips
Each Cerna widefield rig includes accessories for one or more widefield imaging modalities,
chosen to match the needs of your experiment. Each rig has an epi-illuminator paired with
a broadband light source with continuously variable intensity. The transmitted light module is optimized for brightfield, DIC
imaging, or Dodt contrast to help visualize interfaces and structural details in cell cultures and tissue slices.
Compatible with Industry-Standard Objectives and Fluorescence Filter Sets
Cerna rigs are designed to accept M32 x 0.75, M25 x 0.75, or RMS-threaded objectives, Ø25 mm emission filters, and
25 mm x 36 mm dichroics. Adapters for other objective sizes are also available. The epi-fluorescence modules can also
accept beamsplitters for reflected light imaging applications. Objectives and filter sets are available separately from Thorlabs’
extensive optics catalog.
CRW1003 Features
CRW1003: Cerna Widefield Rig with Epi-Fluorescence
and Dodt Contrast
Dodt Contrast Module: Visualize tissue slice structure at visible and NIR wavelengths
with this transmitted light contrast module.
Single-Cube Epi-Illuminator: Perform fluorescence or reflected light imaging.
Multiple markers can be imaged if a multiband filter set is used.
Motorized Slide Holder with 1" of X and Y Travel: Move the sample beneath the
objective to locate the region of interest.
u 1.4
Megapixel, 2/3" Format
Camera
u Trinoculars
with 10X Eyepieces
u Single-Cube
u DC
Epi-Illuminator
Stabilized Light Source
u Dual
Objective Nosepiece
u Rigid
Stand Slide Holder
– 1" of X and Y Travel
– Microscope Slide Holder
u Dodt
Contrast in the Visible
and NIR
u 0.78
NA Condenser
u Motorized
Objective and
Condenser Focus
50 µm
Brightfield Image of an Orchid Ariel Root
Widefield XY Motion and Imaging Options
Thorlabs' widefield rigs feature a modular design that is highly customizable for different experimental needs. Several key
features of three possible widefield imaging rig configurations are listed below. Features can be added or removed to
create a system optimized for your experimental needs.
Item #
XY Motion
CRW1002
CRW1003
Translating Sample
Holder
1" in Both Axes
✓
-
✓
Microscope
Translator
2" in Both Axes
-
✓
-
Single
✓
-
-
Dual
-
✓
✓
Single Filter Cube
✓
-
✓
Filter Cube Turret
-
✓
-
DIC
-
✓
-
Dodt
-
-
✓
Objective Holder
Imaging
CRW1001
Epi-Fluorescence
Transmitted
Illumination
Custom
Contact Our
Applications
Engineers to
Choose the
Features Best
Suited to your
Application
CRW1002: Cerna Widefield Rig with EpiFluorescence and DIC Imaging
CRW1002 Features
DIC Imaging Module: Use DIC to generate contrast in transparent samples
Camera
at visible and NIR wavelengths.
Six-Cube Epi-Illuminator: The filter cube turret enables multi-channel
fluorescence studies by easily switching between filter sets.
Microscope Translator with 2" of X and Y Travel: For experiments where
translation of the sample is not desired or translation of the
microscope is preferred.
u 1.4
Megapixel, 2/3" Format
u Trinoculars
with 10X
Eye Pieces
u Six-Cube
Epi-Illuminator
Turret
u Broad-Spectrum
LED
u Dual
Objective Nosepiece
u Rigid
Stand with
Microscope Slide Holder
u Microscope
Translator with
2"of X and Y Travel
u DIC
50 µm
DIC Image of a Mouse Kidney
Imaging in the Visible
and NIR
u 0.78
NA Condenser
u Motorized
Objective and
Condenser Focus
Electrophysiology Rigs
These Cerna Rigs provide a complete platform for studies
Large Open Working Space
in electrophysiology. Each rig includes options to enable
The 400 mm tall microscope body and 7.74" (196.5 mm) throat
XY motion across the field of view, to visualize and position
depth create a large working volume beneath the objective.
micropipettes, and to obtain images from thin or thick
This slim design provides ample space to comfortably position
samples. The modularity of the rigs makes it possible to mix
the specimen as well as electrophysiology, environmental
and match rig features, combining different modules from
control, and perfusion equipment.
our selection to create the best possible rig for your
experimental demands.
Includes Burleigh® Micromanipulators and Thorlabs'
Rigid Stands
For Cell Cultures, Slice Physiology, and Whole-Animal
Preparations
Each rig includes a pair of Burleigh® micromanipulators
Due to their modularity, these complete imaging systems offer
release clamps that allow components to be easily rotated
a high degree of experimental flexibility, making them ideally
into and out of the optical path. The micromanipulators
suited for a wide variety of needs, including electrophysiology
offer fine, backlash-free, piezo-actuated control with 60 nm
recordings of cell culture, slice, or semi-intact preparations.
resolution, electrically quiet construction to minimize noise in
mounted on Thorlabs’ rigid stands, which feature quick-
patch clamp recordings, and less than 1 µm of drift per hour
in temperature-controlled environments. The rigs are also
compatible with other micromanipulators of your choice.
CRE1001: Cerna Electrophysiology Rig with
Microscope Translator and Dodt Contrast
Dodt Contrast Module: Visualize tissue slice structure at visible and NIR wavelengths.
50 µm
Microscope Translator with 2" of X and Y Travel: Translate the field of view while
the sample and micromanipulators remain stationary on the tabletop, preventing
vibrations that could disturb already established patches.
CRE1001 Electrophysiology Rig
This Cerna rig includes a broad-spectrum
LED for epi-illumination, 1.4 MP camera,
trinoculars with 10X eyepieces, Dodt
contrast module, micromanipulators,
and dual objective
holder. Objectives,
filter cubes, and filter
sets are available
separately.
Dodt Contrast Image of a Mouse Retina
Electrophysiology XY Motion and Imaging Options
Thorlabs' Electrophysiology rigs feature a modular design that is highly customizable for different experiemental needs. The
key features of six possible electrophysiology rig configurations are listed below. Features can be added or removed to
create a system optimized for your experimental needs.
Item #
Translating Sample
Holder
Microscope
Translator
XY
Motion
Translating
Platform
Epi-Fluorescence
Imaging
Transmitted
Illumination
CRE1001
CRE1002
CRE1003
CRE1004
CRE1005
CRE1006
-
✓
-
-
-
-
-
-
✓
✓
-
-
✓
-
-
✓
✓
✓
Single Filter Cube
-
✓
-
-
-
-
Filter Cube Turret
✓
-
✓
✓
✓
-
DIC
✓
-
-
✓
✓
-
Dodt
-
✓
✓
-
-
✓
-
-
-
-
✓
✓
1" in Both Axes
2" in Both Axes
Confocal Imaging
Custom
Contact Our
Applications
Engineers to
Choose the
Features Best
Suited to your
Application
CRE1005: Cerna Electrophysiology Rig with Epi-Fluorescence, DIC
Imaging, and Confocal Imaging
Confocal Imaging System: Obtain high-resolution
fluorescence images of cells and tissue slices at up to
400 fps, with four excitation and detection channels.
DIC Imaging Module: Use DIC to generate
contrast in transparent samples at visible and NIR
wavelengths.
Translating Platform with 2" of X and Y Travel: The
platform provides a large 24" x 18" (600 mm x 450 mm)
surface for holding slides, perfusion chambers,
micromanipulators, or other equipment that
needs to translate together to prevent patch
breakage.
CRE1005 Electrophysiology Rig
This Cerna rig includes a DC-stabilized
light source with liquid light guide for epiillumination, trinoculars with 10X eyepieces,
DIC module, micromanipulators, and dual
objective holder. Objectives, filter cubes,
and filter sets are available separately.
Confocal Imaging Rigs
High-Speed Imaging at up to 400 fps
Our pre-configured confocal rigs include galvo-resonant scan heads
that support scan rates up to 400 fps. Short pixel dwell times minimize
the effects of phototoxicity and unwanted photobleaching.
Antireflection-Coated Scan Lens for 405 - 700 nm
The wide-field-of-view scan lens is color corrected and antireflection
coated to simultaneously support excitation wavelengths down to
the UV and clearly image the deepest-red emitting fluorophores.
Motorized Pinhole Wheel
Light exiting the scan head is spatially filtered through one of sixteen
round pinholes mounted in a motorized wheel controlled through the
ThorImageLS software, allowing the pinhole size to be adjusted from
Ø25 µm to Ø2 mm without the need for realignment.
4-Channel Excitation and Detection Designed to Target
Popular Fluorophores
400 µm
For these confocal imaging rigs, Thorlabs has paired the four
excitation laser wavelengths with a set of filters that match the
emission and absorption profiles of popular fluorophores. Each laser
source features an all-fiber design that minimizes maintenance
Image of a live hippocampal mouse neuron labeled with GFP taken
with Thorlabs’ Confocal Cerna Rig using a 40X, 0.8 NA objective.
Excitation Wavelength: 488 nm.
Courtesy of the 2015 Cold Spring Harbor summer course: "Imaging
structure and function in the nervous system"
and ensures the lasers never go out of alignment, delivering the
full power to the scan head at all times. Removable filter cubes in
the four-channel photomultiplier tube (PMT) module allow the filter
configuration to be easily exchanged by the user.
Transmission (%)
Thorlabs’s Confocal Imaging Systems feature a
Filter Configuration for Source with
405 nm, 488 nm, 561 nm, and 642 nm Lasers
100
modular design that is highly customizable for
different experimental needs. Our applications
engineers are
Filtersavailable to configure a system
80
CWL:
nm/Passto
Bandwidth:
60 nm (Tavg > 93%)
best447suited
your application.
CWL: 525 nm/Pass Bandwidth: 50 nm (Tavg > 93%)
CWL: 593 nm/Pass Bandwidth: 46 nm (Tavg > 94%)
660 nm Longpass (Tavg > 93% up to 1200 nm)
60
ConfocalFluorophores
Laser Sources
40
u Choose One of 10 Preconfigured Laser Sources
DAPI
EGFP
tdTomato
u Available with up to 4 Excitation Wavelengths
Cy5
20
ers
u Each
0
350
400
450
500
550
600
650
700
750
800
Wavelength (nm)
Filters
CWL: 447 nm/Pass Bandwidth: 60 nm (Tavg > 93%)
CWL: 525 nm/Pass Bandwidth: 50 nm (Tavg > 93%)
CWL: 593 nm/Pass Bandwidth: 46 nm (Tavg > 94%)
660 nm Longpass (Tavg > 93% up to 1200 nm)
Fluorophores
DAPI
EGFP
tdTomato
Cy5
750
800
Confocal Laser Source and
Detection Options
The solid lines in the plot show the passbands of the filters, and
the shaded areas show the normalized emission spectra for the
fluorophores.
Source is Paired with the Appropriate
Emission Filter Set
PMT Detection Modules
u Configure
u Easily
with 2 to 4 PMT Channels
Expandable to Allow Additional
Channels to be Added in the Future
u Select
from Standard Multialkali or High-
Sensitivity GaAsP PMTs
CRC1001: Cerna Confocal
System with Dodt Contrast
Four Excitation and Detection Channels:
Simultaneously image multiple fluorescence
markers such as DAPI, EGFP, tdTomato,
CRC1001 Confocal Imaging Rig
This Cerna rig features a complete confocal
imaging system with a fast XY scanning stage for
sample translation. Other components such as a
DC-stabilized light source with liquid light guide for
epi-illumination, 1.4 MP camera, and dual objective
holder are also included.
and Cy5.
Dodt Module for High-Contrast Imaging:
Identify and verify unlabeled structures in
tissue slices prior to confocal imaging.
Fast XY Scanning Stage: Quickly position the
sample with speeds of up to 250 mm/s to
image multiple slides or large well plates. The
stage supports 110 mm of travel in X and
75 mm of travel in Y.
CRC1002: Cerna Confocal System
with DIC Imaging
Four Excitation and Detection Channels:
Simultaneously image multiple fluorescence
markers, such as DAPI, EGFP, tdTomato,
and Cy5.
DIC Module for High-Contrast Imaging: Generate
contrast in transparent samples at visible and NIR
wavelengths.
Translating Platform with 2" of X and Y Travel:
Large, translating 24" x 18" (600 mm x 450 mm)
surface for holding slides, perfusion chambers,
or other equipment that needs to translate
together.
CRC1002 Confocal Imaging Rig
This Cerna rig features a complete confocal
imaging system with an XY translating platform for
sample translation. Other components such as a
DC-stabilized light source with liquid light guide for
epi-illumination, 1.4 MP camera, and dual objective
holder are also included.
Intrinsic Imaging Rigs
Thorlabs' Intrinsic Imaging Rigs are designed to image large areas of the brain
simultaneously in order to observe changes in neural activity.
Slim Design to Maximize Space for Samples and Equipment
These Cerna rigs are based on a 500 mm tall, 95 mm rail, providing a slim
design that maximizes space around the microscope and below the objective
for samples, support apparatus, and other experimental equipment.
Tandem Lens Design Provides Large Field of View and Shallow Depth of Field
The signals produced by intrinsic imaging techniques are often 1000 times
smaller than the background noise, making efficient light collection and
Applications
u Observe
Neural Activity in a
Living Mammalian Brain in
Response to Stimuli
u Image
Vasculature to Create
a Surface Map
u Stimulate
Channelrhodopsin
u Oximetry
shallow depth of field critical for obtaining images of sufficient quality.
Thorlabs’ intrinsic imaging rigs feature a tandem lens with a large Ø41.67 mm
aperture, 1X magnification, high NA of 0.38, and shallow depth of field.
Stable Illumination for Surface Mapping and Probing Underlying
Neural Activity
Stable light sources, such as LEDs, help minimize a source of noise that could
obscure the intrinsic signals that are an indicator of neural responses to
Illumination Wavelengths
u 470
nm for Stimulating
Channelrhodopsin
u 565
nm for Imaging Vasculature to
Create Surface Maps
stimuli. Thorlabs has equipped our intrinsic imaging rigs with a 4-wavelength
u 617
nm for Performing Oximetry
LED source that uses a Ø3 mm core liquid light guide to deliver even
u 660
nm to Probe Signals of Neural
illumination to the sample.
Activity Beneath the Sample Surface
Low-Noise Camera for High-Resolution, Large-Area Images
Intrinsic Imaging requires recording signal over a large field of view, relying
on large-format cameras with small pixels to avoid having the camera limit
Noise Scientific Camera with an 18.13 mm x 13.60 mm sensor area and
5.5 µm x 5.5 µm pixels. 14-bit output provides sufficiently fine brightness
resolution to capture the tiny fluctuations in signal that indicate neural
activity, allowing this information to be extracted later during the image
processing stage.
5
Power (mW)
resolution. Thorlabs’ intrinsic imaging rigs each include an 8 Megapixel Low-
LED Spectra
6
4
470 nm
565 nm
617 nm
660 nm
3
2
1
0
400
450
500
550
600
650
Wavelength (nm)
Typical LED Output Power through a Ø3 mm Liquid
Light Guide
Intrinsic Imaging Rig Options
Thorlabs’ Intrinsic Imaging Rigs all feature modular designs that are highly customizable for different experimental needs.
Our applications engineers are available to configure a system best suited to your application.
u LED
Illumination: Thorlabs offers 4-Wavelength LED Sources with over 100 different preconfigured wavelength
combinations. Our applications engineers can explore options to determine which combination best suits
your experiment.
u XY
Translation: In addition to the translating rigid stand and translating microscope featured on the facing page,
these rigs can also be configured with Thorlabs’ Large Translating XY Platform (as seen on Thorlabs’ CRC1002
Confocal Rig) for applications that require the sample and experimental equipment to be moved together.
u Camera:
In addition to our 8 Megapixel Scientific Camera, Thorlabs also offers Fast Frame Rate, 4 Megapixel, and
1.4 Megapixel scientific cameras. If you believe that another camera might be better suited to your application,
contact our applications engineers to discuss options.
700
CRF1001: Cerna Intrinsic Imaging Rig with Translating Sample Platform
Sample Platform with 1" of Travel in X and Y:
Tandem Lens and 8 MP Low Noise Camera:
Samples can be smoothly positioned
The camera and tandem lens produce large-area,
beneath the tandem lens. The slim design
high-resolution images.
of the rigid stand maximizes space on
the optical table for other parts of the
experimental apparatus, while the
Four-Wavelength LED Source: Provides stable, even
sample illumination.
platform is large enough to hold a small
sample preparation and a stand for the
liquid light guide.
CRF1001 Intrinsic Imaging Rig
This Cerna rig features a sample
platform with 1" of motorized translation
in X and Y. A camera and tandem lens
with motorized focus control and fourwavelength LED source with controller
are also included.
CRF1002: Cerna Intrinsic Imaging Rig with Translating Microscope
Microscope with 2" of Travel in X and Y:
Tandem Lens and 8 MP Low Noise Camera:
Change the field of view without disturbing the
The camera and tandem lens produce large-
sample. This rig includes a stationary rigid
area, high-resolution images.
stand that maximizes space on the optical
Four-Wavelength LED Source: Provides stable,
table for other parts of the experimental
apparatus, while the platform is large enough
even sample illumination.
to hold a small sample preparation and a stand
for the liquid light guide. Alternatively, the stand
can be removed to accommodate
larger samples.
CRF1002 Intrinsic Imaging Rig
This Cerna rig features 2" of
motorized microscope translation
in X and Y. A camera and tandem
lens with motorized focus control
and four-wavelength LED source
with controller are also included.
Complete Optical Paths: Cerna Microscope Bodies
For the researcher who desires a more hands-on approach to setting up their microscopy system, Thorlabs offers a line of
microscope bodies that feature complete optical paths. Light sources, detectors, filter cubes, filter sets, objectives, and
sample holders are available separately, allowing the microscope body to be easily customized and modified by exchanging
modules as your experimental needs grow.
Slim Profile Maximizes Table Space
All Cerna microscopes feature a slim design that eliminates the massive base
and housing of typical microscopes, maximizing table space. The simplest
Cerna microscopes have a path for epi-illumination only, making them ideal
for experiments involving large, intact samples that are too thick for imaging
techniques that use transmitted illumination.
Image Multiple Fluorescence Channels
The microscope to the left features a six-cube epi-illuminator, useful for creating
images of multiple fluorescence channels. Microscopes are also available with
a single-cube epi-illuminator for reflected light imaging or viewing multiple
fluorophores through the use of a multi-band filter set.
Motorized Focus Control
The objective holder accepts industry-standard objectives from major
manufacturers such as Olympus and Nikon. Like all of our Cerna microscopes, the
objective height can be adjusted by 1" using the motorized focus control.
CM1002
Cerna Microscope Body without
transmitted illumination for
imaging large, intact preparations
(optical table not included).
Transmitted Illumination: Brightfield, Dodt Contrast, and DIC Imaging
For thinner samples, Cerna microscopes are available in configurations to
support brightfield, Dodt contrast, or DIC imaging.
High-Contrast Imaging of Unlabeled Samples
Both Dodt and DIC imaging techniques create high-contrast images of unlabeled
samples. DIC imaging produces the best contrast in thinner samples, while Dodt
contrast imaging can produce comparable results in thicker samples that are
difficult to image with DIC.
Translating Microscopes and Platforms
Thorlabs offers Cerna microscopes configured with a translating platform that can
accommodate large samples and experimental apparatus. We can also
install microscope translators, allowing the sample to remain stationary
on the table while the field of view is adjusted.
Customization is Simple
Due to their modular design, the microscopes can be
easily modified, allowing our applications engineers to
optimize the microscope for the needs of each researcher.
CM3003
Cerna Microscope Body
with DIC and a translating
platform (optical table not
included).
Accessories
To prepare your Cerna microscope for imaging, select from a wide array of compatible accessories offered by Thorlabs and
other microscope companies. Thorlabs-manufactured Cerna accessories are designed and tested entirely in house, letting us
tailor the features of each component and ensure that the desired performance is achieved.
Illumination
Filter Cubes and Filter Sets
Thorlabs offers a variety of high-power sources for epi- and
Fluorescence excitation and emission filter sets are
transmitted illumination, including LEDs and a DC-Stabilized
available for a popular fluorophores, including DAPI,
Light Source.
tdTomato, and GFP.
Rigid Stands
Rigid stands are rotatable, lockable, low-profile platforms that hold recording
chambers, slides, multiwell plates, and other experimental equipment.
Insert Holder
with Z-Axis
Piezo Stage
Scientific Cameras
Slide Holder
Recording
Chamber
Holder
Objectives
Scientific cameras are especially useful for DIC imaging,
Cerna microscopes accept objectives with M32 x 0.75,
Dodt contrast, and patch visualization.
M25 x 0.75, or RMS threads. Adapters for other objective
sizes are also available.
Build Your Own Microscope
Large Selection of Microscopy
Components
Dovetail System for Easy Construction
For the ultimate flexibility, Thorlabs offers all of the modules
with a dovetail that allows many of the Cerna modules to be
used in our Cerna Rigs and Microscopes as stand-alone
positioned flexibly along the length of the microscope body.
components. In addition to opening a path for future
Cerna components that do not connect directly to the
upgrades for users, the modules allow the integration of
95 mm rail use round dovetail connectors for ease of
microscopy components with Thorlabs’ wide selection of
assembly. All compatible modules are designed to have a
optomechanics and optics.
7.74" (196.5 mm) throat depth to provide excellent clearance
The Cerna system is based on a rigid optical construction rail
between the optical path and the microscope body.
1X Camera
Tube
400 mm
350 mm
Broadband
Light Source
Double
Camera Port
Trinoculars
The Cerna system’s 95 mm support rail provides a stable mounting platform
that allows flexible positioning of each part of the microscope, while
minimizing the footprint on the optical table.
6-Cube
Epi-illuminator
Dual
Objective
Nosepiece
0.78 NA
Condenser
Transmitted Light
Module with DIC
Accessories
Controller for
XY Motion
Rigid Stand
Slide Holder
Cerna microscope shown
with a double camera
port and DIC imaging
accessories.
Controller for
Objective and
Condenser Focus
Options at a Glance
Widefield Viewing
Motion Control
uXY
Magnification
uLarge
uTrinoculars
uMicroscope
uDouble
uMotion
uCamera
Tubes with 1X, 0.75X, and 0.5X
with Upright or Inverted Images
Camera Ports with Fixed or Variable
Magnification
Stage for Rigid Stands
Platform with 2" of X and Y Travel
Movers with 2" of X and Y Travel
Control Accessories Use the Same Type of 3-Axis
Controller as the Objective and Condenser Focusing
Transmitted Illumination
and Ø25 mm Filters
uBrightfield,
Dodt Contrast, and DIC Imaging
Modules
uCondenser
uAir
Stage with 1" of Motorized Travel
and Oil Immersion Condenser
uEasy-to-Reach
Filter Cubes Accept 25 mm x 36 mm Dichroics
Accessories for System Developers
uFixed
Arms with SM1, SM2, 30 mm Cage System, and
60 mm Cage System Compatibility
Sample Holders
Our developers’ accessories let you incorporate your own optical
uRigid
Stands that Accept Recording
uBreadboard
Top for Custom Illumination
Chambers, Microscope Slides, a Z-Axis Piezo
system designs directly into the microscope body. We manufacture
Stage, and More
fixed arms that connect Thorlabs’ Ø1” lens tubes, Ø2” lens tubes, 30 mm
cage systems, and 60 mm cage systems to the dovetail. Thorlabs’ 95
uFast
XY Scanning Stage with Z-Axis Piezo
mm construction rail accessories
Stage Insert
uFixed
Arms to Attach Sample Holders Directly
to the Microscope Body
Epi-llumination
uSingle-Cube
uSix-Cube
to the dovetail, providing
another avenue for building
custom modules that can be
Epi-Illuminator for Reflected Light
or Single Fluorescence Channel Imaging
can be connected directly
Epi-Illuminator with Filter Turret for
Co-Registered Images of Multiple
Fluorescence Channels
easily installed and removed. A
breadboard accessory designed
to sit on top of the support rail
(shown below) is also available
for building custom optical
pathways.
Sales Contact
Our dedicated Thorlabs sales team is ready to help you
achieve your goals. Whether you are seeking more
information or are ready to make a purchase, please
contact us for immediate assistance.
(703) 651-1700
u
ImagingSales@thorlabs.com
Cerna microscope
shown with homebuilt epi-illuminator
and Thorlabs’ lens
tubes and cage
systems.
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www.thorlabs.com
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Phone: 1-973-300-3000
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Email: sales.uk@thorlabs.com
56 Sparta Avenue • Newton, New Jersey 07860
Sales: 973.300.3000 • Fax: 973.300.3600 • www.thorlabs.com
Phone: +46 31 733 30 00
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