Synchro for pdf 27/05/03 17:27 Page i European Commission Community research Synchrotron Light and Free-Electron Lasers Project repor t RESEARCH INFRASTRUCTURES IMPROVING THE HUMAN RESEARCH POTENTIAL AND THE SOCIO-ECONOMIC KNOWLEDGE BASE Synchro for pdf 27/05/03 17:27 Page ii Interested in European research? RTD info is our quarterly magazine keeping you in touch with main developments (results, programmes, events, etc.). It is available in English, French and German. A free sample copy or a free subscription can be obtained from: Directorate-General for Research Communication Unit European Commission Rue de la Loi/Wetstraat 200 B-1049 Brussels Fax (32-2) 29-58220 E-mail: rtd-info@cec.eu.int Internet: http://europa.eu.int/comm/research/rtd-info.html EUROPEAN COMMISSION Directorate-General for Research Programme: ‘Improving the human research potential and the socio-economic knowledge base’ Contact: C. Warden European Commission Rue de la Loi/Wetstraat 200 (SDME 3/46) B-1049 Brussels Fax (32-2) 29-63270 E-mail: campbell.warden@cec.eu.int Website: http://www.cordis.lu/improving Synchro for pdf 27/05/03 17:27 Page 1 European Commission Research infrastructures Synchrotron Light and Free-Electron Lasers Ten years of transnational research in Europe The European Round-Table on Synchrotron Radiation and Free-Electron Lasers by Professor G. Margaritondo, Round-Table Coordinator Editor: Campbell Warden (European Commission) Improving the human research potential and the socio-economic knowledge base Directorate-General for Research Synchro for pdf 27/05/03 17:27 Page 2 LEGAL NOTICE Neither the European Commission nor any person acting on behalf of the Commission is responsible for the use which might be made of the following information. A great deal of additional information on the European Union is available on the Internet. It can be accessed through the Europa server (http://europa.eu.int). Cataloguing data can be found at the end of this publication. Luxembourg: Office for Official Publications of the European Communities, 2000 ISBN 92-828-8506-2 © European Communities, 2000 Reproduction is authorised provided the source is acknowledged. Printed in Belgium PRINTED ON WHITE CHLORINE-FREE PAPER Synchro for pdf 27/05/03 17:27 Page 3 Table of Contents Page 5 FOREWORD 7 EXECUTIVE SUMMARY 9 9 9 THE PRODUCTION OF X-RAY BEAMS 1. Introduction 2. How X-ray beams are produced 13 13 14 15 17 17 THE USES OF X-RAY BEAMS 1. Radiology 2. Crystallography 3. Chemical and Biochemical applications 4. Manufacturing 5. Fundamental Research 19 19 21 THE FUTURE 1. More Intense Sources 2. Increasing Variety of Usage 23 23 25 25 26 28 30 EUROPEAN COORDINATION 1. Transnational Usage 2. The “Round-Table” – History – Activities – Results – Looking to the future 31 31 ANNEX 1 Round-Table Membership 3 Synchro for pdf 27/05/03 17:27 Page 4 The Synchrotron and Free-Electron Laser (FEL) facilities participating in the RoundTable are located in seven different countries and offer an advanced network of experimental resources to all European scientists. 11 10 6 5 4 2 8 3 9 12 13 1 7 Centres participating in the European Round-Table in Synchrotrons and Free-Electron Lasers 1. Elettra (Italy) 2. Bessy (Germany), 3. LURE (France), 4. SRS-Daresbury (United Kingdom), 5. HASYLAB (Germany), 6. EMBL-Hamburg (Germany), 7. EMBL-Grenoble (France), 8. FELIX (The Netherlands), 9. CLIO (France), 10. MAX-Laboratory (Sweden), 11. ISA (Denmark), 12. ANKA (Germany), 13. SLS (Switzerland). 4 Synchro for pdf 27/05/03 17:27 Page 5 FOREWORD Many fields of European research are underpinned by access to world-class research infrastructure. However, the majority of such facilities are owned by National Government agencies and they are open only to their national user community. In view of this, successive European Commission (EC) Research and Technological Development Programmes, ‘Framework Programmes’, have created “Win-Win” situations by supporting transnational access to a select group of outstanding research infrastructures. A clear example of such mutual benefit is provided by the EC support of research infrastructures by funding the activities of a series of Round-Tables, which have brought together the operators and representatives of the user community of a particular class of facilities around a common research theme. This has enriched the scope and impact of each group beyond its own narrow national boundaries. These Round-Tables have been much more effective than ‘usual’ interactions between scientists because they have guaranteed the participation of the full range of institutional facilities and the representatives of the users, avoiding obvious problems of narrow or partisan actions. Their mission has focused on finding and implementing the solutions to problems of common interest and seeding new transnational collaborations. The EC support for transnational access and the Round-Table has made a major contribution to the development over the last ten years of the field of Synchrotron Radiation and Free-Electron Lasers. More than 36.7 million Euro has been allocated, primarily to support transnational users at national facilities, with more than 600 scientists in the 1996-98 period alone, who performed hundreds of experiments that would have been impossible without this support. This brochure has been prepared by the Coordinator of the Round-Table for Synchrotron Radiation and Free-Electron Lasers and it provides useful information both to the researchers active in this field and to those responsible for developing new research infrastructure for it. I am very pleased to present this excellent example of how to develop multi-national research co-operation for those who are working in fields where such a highly developed culture of cross-border co-operation does not yet exist. The EC wishes to continue to encourage such development. Therefore through the activity “Enhancing Access to Research Infrastructures” of the Improving the Human Research Potential and the Socio-economic Knowledge Base Programme, it will make available during the period 2000-2003 at least 180 million Euro to support access to top-class research infrastructure. Achilleas Mitsos Director Improving the Human Research Potential and the Socio-economic Knowledge Base 5 Synchro for pdf 27/05/03 17:27 Page 6 The Austrian Academy’s small-angle X-ray scattering beam line is an excellent example of transnational use of a national facility. The beam line enables Austrian scientists to take full advantage of the Elettra Synchrotron in Italy – and enhances the international impact of Elettra. The diffraction pattern shown here was taken at the Austrian beam line and reveals mesoscopic order in rubber-like systems. 6 Synchro for pdf 27/05/03 17:27 Page 7 EXECUTIVE SUMMARY Europe operates one of the most advanced synchrotron light sources in the world, namely the ESRF (European Synchrotron Radiation Facility) in Grenoble. In addition, several countries have developed smaller-scale Synchrotrons and Free-Electron Lasers that have advanced technical characteristics. In some cases, synchrotron experiments strictly require the high-photon energies and specialised equipment of ESRF. In other cases, European scientists can be equally, or even more efficiently, served by the “national” facilities, provided that they have effective transnational access to them. Thanks to the support provided under successive European Commission (EC) ‘Framework Programmes’, and to the coordinating action of the Round-Table, the entire array of “national” Synchrotrons and Free-Electron Lasers installed at the centres participating in the “European Round-Table in Synchrotrons and Free-Electron Lasers”, were “opened up”. Without this, the typical users of these research infrastructures, who are from small groups with limited resources, would have found it difficult to finance travel and subsistence, never mind any user fees. Access was provided to qualified researchers from the EU and Associated States on the basis of merit, after peer review. Although these facilities were developed as national institutions they now constitute a superb research system that is serving the needs of both the European scientific community and European industry. The figure opposite shows one of the many examples of the results of this transnational access. On 21 May 1999, scientists from all over Europe gathered in Paris for a symposium to celebrate the tenth anniversary of the creation of the “European Round-Table for Synchrotron Radiation and Free-Electron Lasers”. The research domains discussed at the meeting are presented in Chapter 4, “The Uses of X-ray Beams”. This brochure also contains: • An explanation of how X-ray beams are produced (Chapter 3); • a vision of the future, with some reasonable projections about “More Intense Sources” and the “Increasing Variety of Usage” (Chapter 5); • a synopsis of the role of the aforementioned Round-Table in coordinating these developments (Chapter 6). It is a pleasure for me to present this publication in the hope that its description of the past, present and probable future, of X-Rays and their scientific uses, will be of interest, not only to the scientific community, but also to funding agencies and policy makers. Giorgio Margaritondo Round-Table Coordinator 7 Synchro for pdf 8 27/05/03 17:27 Page 8 Synchro for pdf 27/05/03 17:27 Page 9 THE PRODUCTION OF X-RAY BEAMS 1. INTRODUCTION Light has always been a fundamental tool for exploring the physical world. Progress in science goes in parallel with the technical progress in producing and using “light” at different wavelengths to explore the physical world, from our ancestor’s fires to the Röntgen’s X-rays and to modern lasers. The effective production of light still encounters serious technical difficulties. This is particularly true for “light” in the low-wavelength domain of X-rays. Low-wavelengths are most effective to explore the inside of the human body in radiology, to unveil the secrets of the chemical bonds in molecules and solids and to explore the spatial arrangements of atoms in the same systems. As a consequence, X-rays are in very high demand in medicine, science and technology. Yet, until quite recently the available Xray sources were far from satisfactory. Could we produce X-rays in the same way that we produce radio waves, by forcing electric charges to oscillate along an antenna? The problem is that X-ray wavelengths are extremely short (less than one tenth of a millionth of a millimetre). Thus, the charge oscillation would have to take place at extremely high frequency, which is technically impossible. The solution to this problem is a clever use of Einstein’s theory of relativity. 2. HOW X-RAY BEAMS ARE PRODUCED Suppose that an electron circulates in a ring-shaped tube under vacuum, with its motion controlled by a well-designed system of electric and magnetic fields. Imagine the electron in a portion of the ring free of forces: elementary mechanics teaches us that the electron moves at constant speed along a straight line. Suppose now that this straight constant motion is slightly perturbed, by inserting around the electron trajectory a periodic array of magnets. The magnets force the electron to weakly “undulate” around its former straight trajectory. Seen from the front, the electron looks very much like an oscillating charge in a radio antenna. One can thus guess that the electron emits “light”: that is, it emits electromagnetic waves, whose wavelength “λ” equals the period “L” of the magnet array. A reasonable magnitude for the period length “L” is a few centimetres, so “λ” should fall in the spectral domain of radio waves. This conclusion, however, is no longer valid if the electron moves along the ring at very high speed, approaching “c”, the speed of light. Classical physics is unable to provide correct answers, and we must analyse the phenomenon using Einstein’s theory of relativity. Röntgen discovered X-rays more than 100 years ago – and almost immediately took the first radiological image. After one century, however, X-ray sources have not yet reached their best possible performances. The text illustrates the best solution to this crucial problem. The result is quite simple: from the point of view of the fast-moving electron, the length “L” appears shorter because of the relativistic “Lorentz contraction”. Thus, the emitted wavelength is also shorter. The contraction 2 is “L/γ”, where “γ” is the relativistic “gamma” factor γ = E/moc (mo = electron rest mass). In other words, “γ” is the electron energy “E” measured 2 in units of Einstein’s electron “rest energy”, moc . In a modern electron accelerator or storage ring, the gamma-factor is of the 3 4 order of 10 - 10 , shifting the emitted wavelength from the centimetre range of “L” to the millimetre range. But this shortening is not the only relativistic effect. In fact, L/γ is the emitted wavelength as it is observed from the point of view of the emitting electron. Seen from the laboratory reference frame, the electron is a fast moving source, thus its emitted wavelength is subject to the shift called Doppler effect, the well-known phenomenon which changes the pitch of a train siren as the train moves with respect to us. The Doppler effect for light is a relativistic phenomenon, and the corresponding wavelength change is an additional shortening by a factor of approximately “2γ”. 9 Synchro for pdf 27/05/03 17:28 Page 10 The two combined relativistic effects shorten the wavelength by an overall 2 2 2 6 8 approximate factor (γ)(2γ) = 2 γ , so that λ ≈ L/2 γ , with γ = 10 - 10 . Thus, relativity takes a magnet-array period “L” of the size of centimetres, -8 -10 and transforms it into a wavelength of 10 - 10 meters, typical of X-rays. The above description, although simplified, includes the essential elements of a Synchrotron X-ray source: a high-energy storage ring for circulating electrons and one or more periodic arrays of magnets (called “wigglers” or “undulators” depending on the strength of the magnets) in its straight sections. One must add suitable beamlines to collect the emitted X-rays and convey them into experimental chambers for a variety of practical uses. How good is a synchrotron source with respect to other X-ray sources? We must respond by considering the source brightness or brilliance. This notion can be understood based on our everyday experience: a powerful light source is often less useful than a very “bright” source. Compare for example a normal lamp in the home to a torchlight. The latter may be less powerful but it concentrates the light in a narrow cone, becoming very “bright” and therefore useful to see things in a dark room. A similar conclusion is valid for the headlights of a car or for a laser. A synchrotron source is extremely bright: the electrons in the ring are moving so fast that their emitted “light” – or synchrotron radiation – is projected ahead and confined to an extremely narrow cone. A similar effect is present for sound emitted by a train. Once again, however, relativity intervenes pushing the effect to the limit. The angular aperture of the emitted light cone is of the order of 1/γ and therefore not larger than -3 -4 10 - 10 radians. Therefore a synchrotron source, without operating like a laser, can nevertheless reach the angular collimation of a laser! The quality of X-ray sources must then be assessed in terms of their brightness. Unfortunately, X-ray brightness did not significantly improve after Röntgen’s original devices and until the advent of synchrotron sources in the 1960’s. During the 1970’s, 1980’s and 1990’s, spectacular advances in synchrotron technology produced a brightness increase by some fifteen orders of magnitude. By comparison, if the power of a common light bulb had been increased by the same amount, its consumption would be one hundred thousand times larger than the total power production of the entire world! The laser-like properties of synchrotron X-ray sources are extremely useful for a broad variety of applications. In addition, the capability to control fastmoving electrons is exploited to construct true laser sources. Each type of laser is based on optical phenomena occurring in an active medium; for example, the laser source inside a compact-disk player uses a semiconductor as active medium. Moving electrons interacting with a “wiggler” or an “undulator” can also act so as to become an active medium producing laser 10 light. The corresponding device is called a Free-Electron laser or FEL. Up until now, technical problems have confined the FEL technology to rather long wavelengths: FEL were primarily used as very bright sources of infrared light. But the technology is rapidly improving, and the first X-ray FEL are under development. Their characteristics and applications complement those of synchrotron sources. Relativity at work to produce X-rays First effect: Lorentz contraction, seen by the moving electron, the undulator period L decreases to L/γ. Second effect: Doppler shift, the “undulating” electron emits synchrotron light of wavelength L/γ in its frame. In the lab frame, the wavelength L/γ is Doppler-shifted 2 becoming ≈ L/2γ . Synchro for pdf 27/05/03 17:28 Page 11 A torchlight is a small-area source with small angular divergence: its brightness is high and it can illuminate small areas with high intensity. The advent of synchrotron sources marked the beginning of spectacular improvements in the performances of X-ray sources. In particular, the source brightness (in conventional units photons/mm2/s/mrad2, 0.1% bandwidth) has increased by one hundred thousand billion times in 25 years. 1021 1018 1015 Advent of synchrotron sources 1012 109 106 1900 1940 1980 11 Synchro for pdf 12 27/05/03 17:28 Page 12 Synchro for pdf 27/05/03 17:28 Page 13 THE USES OF X-RAY BEAMS 1. RADIOLOGY Why are we so preoccupied about getting good sources of X-rays? The answer is, of course, that X-rays are extremely important and useful. To appreciate this point, we do not need to go beyond our everyday experience. X-rays are the magic light which help us to “see” inside our body, to find out what is wrong and what can be done about it. Its usefulness notwithstanding, radiology is still subject to severe technological limitations, primarily due to the X-ray sources. The human and sociological consequences of this can be quite dramatic. Consider for example breast cancer in women. With early diagnosis, very effective therapies can beat this otherwise merciless murderer. But early diagnosis would require regular X-ray screening, which raises concern because it exposes the patient to a non-negligible radiation dose. Thus, early detection is not yet systematically achieved, and breast cancer is still a major killer disease. Techniques like “phase-contrast” radiology or “diffraction-enhanced imaging” yield excellent radiographs with a sharply reduced radiation dose. Tests on anatomical specimens are very encouraging, and the first experiments on human patients are underway. Thus, some years from now, synchrotron sources could become as common as the present X-ray sources in dental or medical clinics. But they will be much more effective and safer. Furthermore, refractive-index-based radiology can be used to “look inside” not only the human body, but also technological materials. Why are radiation doses still too high to be universally acceptable? A key problem is that contrast in radiology is based on the different levels of Xray absorption by different tissues. However, as the variances between tissues are quite small, obtaining good images requires non-negligible amounts of X-rays. One could adopt a completely different approach. When a light beam travels in a semi-opaque solid, it is subject to different phenomena: it is partially absorbed, but also refracted. Refraction means that the light beam changes its direction. Such changes are particularly important at the irregular border between two differently refracting regions, and can produce sharp images of such borders. Likewise, other effects (such as Fresnel edge diffraction) can produce border enhancement, which is also related to the refractive index. Border enhancement depends on how different the refraction and the refractive index are between the two regions. Note that refraction differences between different tissues are typically larger than the absorption differences. Thus, refraction could be a very effective replacement for absorption when performing a radiological analysis. However this is quite unrealistic with conventional X-ray sources. Refractionbased imaging can be observed only if the light beam has a well-defined direction, implying strong collimation. This can be observed with a laser, but not with a light bulb whose emission is in all directions and, therefore, not collimated. Likewise, refraction-based radiology is impossible with conventional, noncollimated X-ray sources, which are comparable to light bulbs. Laser-like synchrotron sources make it possible, producing very spectacular results. Can we improve a radiological image without increasing the X-ray dose? This is not easy with a conventional X-ray source. When a synchrotron source is used, the image can be dramatically improved while the X-ray dose is sharply reduced. The possible medical applications of this technique are under consideration at several European laboratories. Figures courtesy of G. Tromba. 13 Synchro for pdf 27/05/03 17:28 Page 14 2. CRYSTALLOGRAPHY Crystallography has been described as a new window for biology and a key to novel drugs. After radiology, it is the second most popular use of X-rays. It is in fact an extremely useful technique to identify the positions of individual atoms in solids and molecules. This technique is based on the diffraction of X-rays by a system of periodically arranged atoms. Since the spatial period is of the order of a few tenths of a millionth of a millimetre, the diffracted wavelength must be in the spectral range of X-rays. Crystallography has produced many fundamental results, such as the “double helix” structure of DNA, and the highest number of Nobel awards of all research techniques. Its applications are currently in a state of explosive growth. The fastest growing sub-domain is protein crystallography, a technique which analyzes the structure of macromolecules formed by tens of thousands of atoms. The proteins are “crystallized”, which means that they are arranged in a periodic structure suitable for crystallography. Synchrotron light is essential for protein crystallography. In fact, the most powerful protein crystallography approach – known as “MAD” (Multiplewavelength Anomalous Diffraction) – requires adjustable wavelengths, which only synchrotrons can provide. The explosive growth of protein crystallography is the result of several factors. First of all, the microscopic structure is extremely important in biological systems. One striking example is the recently identified structure of ATP-synthase, which enables this macromolecule to transform the energy required for physiological functions. Synchrotron crystallography at the Daresbury laboratory led to the clarification of this fundamental mechanism in animals and humans, and to John Walker’s Nobel prize. The second growth factor is that synchrotron crystallography is becoming an essential tool for the pharmaceutical industry. Some of the most advanced drugs mimic the local structure of viruses, to attack them and/or inhibit their functions. The development of a single new product of this type starts with the analysis of the microscopic structure of thousands of potential drugs. Synchrotron sources are essential: they speed up the entire process, and their brightness is required when the available specimens are too small. Finally, crystallography is becoming a fundamental component of genomerelated research. The huge international effort to map the human genome is well known. A crystallography programme of comparable magnitude is under development, requiring synchrotron sources for three-dimensional structure determination. The above factors combined create an unprecedented demand for synchrotron light and for the related crystallography facilities, as confirmed 14 Synchrotron-based crystallography is in a state of explosive growth. Its applications range from fundamental problems to very practical questions in pharmaceutical research. Advanced crystallography techniques identify with high accuracy the positions of thousands of atoms in complex molecules. The figure shows one nice example: the overall structure of Human Topoisomerase I in complex with DNA determined by X-ray crystallography with data from SSRL, NSLS, CHESS, and ESRF. Figure courtesy of M. Redinbo. Synchro for pdf 27/05/03 17:28 Page 15 by a recent comprehensive analysis of this domain by the European Science Foundation. The growth rate exceeds all expectations, in particular for genome-related studies. Even the most conservative projections predict a sustained expansion for several years and then a steady use for at least two decades. In summary, crystallography has become the leading and fastest growing application of synchrotron light. The related demand for synchrotron sources strains the entire European network as well as facilities world-wide. This enhances the need for open access and coordination. 3. CHEMICAL AND BIOCHEMICAL APPLICATIONS A synchrotron source can be used as a powerful “chemical” microscope: it reveals the chemical structure of materials on the scale of a few ten millionths of a millimetre. The figure shows a rather spectacular example: the phenomenon of “chemical waves” on a metal surface, imaged by scanning photoelectron spectromicroscopy by M. Kiskinova et al. Synchrotrons and FEL have been used for decades to perform extremely accurate chemical analysis. Techniques like photoelectron spectroscopy, Xray absorption and infrared spectroscopy deliver detailed information not only on the chemical composition but also on the chemical status of each element and on the fine properties of the corresponding chemical bonds. The recent novelty is high lateral resolution. In the past, synchrotron-based chemical analysis was blind to important properties on a scale of less than one-tenth of a millimetre. At present, the scale reaches twenty billionths of a millimetre. Important examples are photoelectron spectromicroscopy with synchrotrons and scanning near-field optical microscopy (SNOM) with FEL. Microscopic-scale chemical analysis is extremely important for many reasons. For example, it can detect fundamental microscopic mechanisms that are invisible to conventional techniques. Moreover, by reducing the probed area, chemical analysis increases its minimum detectable concentration of trace elements. There are important applications in biological and ecological research. In biology, the typical scale length is that of cells and of cell components: a fraction of a thousandth of a millimetre. Analysis on that scale investigates the chemistry of physiological, pathological and therapeutic mechanisms. For example, one can detect trace contamination of cells due to pollution, or assess the effectiveness of chemical therapies of several types of cancer. In ecology, microscopic-scale analysis detects pollution-related trace contamination of solid specimens. For example, it can detect radioactive contamination in specimens with extremely limited overall radioactivity, which are easy to handle and transport. It can also detect minute amounts of contamination in food products. 15 Synchro for pdf 27/05/03 17:28 Page 16 How can one fabricate moulds on the scale of a few thousandth of a millimetre? The accompanying text reveals the secret: the synchrotron-based technique known as “LIGA”. 0.1 mm 0.01 mm 1 cm Microfabrication with Synchrotron radiation can squeeze a turbine into less than one-half millimetre. Fabrication technologies of this type may trigger a new industrial revolution, similar to the miniaturisation of electronic devices three decades ago. 0 cm In a simple metal, a current-carrying “free” electron is actually subject to many forces due to atoms and other electrons. Amazingly, it still behaves pretty much like an electron which is really free – as proposed by the theory known as “Fermi liquid”. -e, s -e, s -e, s -e, s -e, s -e, s -e, s -e, s -e, s -e -e, s -e -e, s s -e s -e -e -e s s s -e 16 s s -e s -e -e -e In low-dimensional metal this may no longer be true. Instead of electron-like “quasiparticles” with charge and spin, one might have particles with charge and no spin (holons) and particles with spin and no charge (spinons). Sophisticated Synchrotron spectroscopy experiments are excellent tools to explore this intriguing possibility. Synchro for pdf 27/05/03 17:28 Page 17 4. MANUFACTURING 5. FUNDAMENTAL RESEARCH X-rays are a tool not only for medical, biological and materials analysis, but also for industrial fabrication. Advanced processing in microelectronics is based on photolithography. The ever-increasing miniaturisation requires light with shorter and shorter wavelengths. The present fabrication uses ultraviolet sources, and many experts believe that X-ray lithography will be next. The practical use of Synchrotrons and FEL goes hand-in-hand with many applications in fundamental science. X-ray photoelectron spectroscopy with Synchrotron light is an excellent example. Its energy resolution, limited to 50 millivolts until quite recently, now reaches 4-5 millivolts. This unlocks a new world of unexplored phenomena. Many synchrotrons host research and development programmes in X-ray lithography. This technique is already mature and ready for use by industry, when the need arises. Microelectronics lithography is a two-dimensional process, since the fabrication of complex devices is performed layer-by-layer. X-rays, however, can also penetrate in the third dimension, and can be used to fabricate ultraprecise moulds for micromechanical parts. Therefore, another type of X-ray lithography is under development for micromechanics, “LIGA”. With collimated synchrotron light, one achieves almost incredible levels of mechanical accuracy. Microparts can be as small as a few thousandths of a millimetre and their walls can be as accurate as a fraction of a thousandth of a millimetre. These futuristic microfabrication techniques are preparing the way for new industrial revolutions. For example, functions now digitally handled by microelectronic devices could be performed by analogic micromechanical devices. “Smart pills” could release drugs according to the patient’s needs, measured by built-in chemical sensors and controlled by built-in microcomputers. From a more mundane point of view, many industries will benefit from extremely high accuracy in fabricating microfilters for liquids. Condensed matter “seen” with an energy filter of 50 millivolt is pretty well understood; when the filters shrinks to 4.5 millivolts, it reveals mysterious aspects. With 50 millivolt resolution, the free-electrons in a metal behave almost like free-electrons in vacuum, still “looking like” charged particles with 1/2 spin. The theoretical framework is the Fermi liquid, which explains the properties of a metal treating its electrons as a “liquid” of nearly-free particles. The Fermi liquid is the very foundation of solid-state science. But this foundation becomes shaky when low-dimensional solids are observed with a 4-5 millivolt resolution filter. Sometimes, one no longer observes anything similar to electrons with charge and spin. Instead, particles with spin and no charge (spinons) and particles with charge and no spin (holons), can be “seen”. The “accepted” understanding of ‘free-electrons’ and ‘Fermi liquid’ breaks down in these extreme cases. This is a rather revolutionary result, made possible by advanced Synchrotron sources. Theories beyond the Fermi liquid are rare and of limited scope. Until now, they were not really needed. But this has been changed by Synchrotron light and ultra-high resolution. The impact is likely to be quite strong, for example on high-temperature superconductivity. Fifty years ago, the first steps in electronic miniaturisation prepared a complete revolution of our lifestyle. The present first step in micromechanics could lead to a comparable result, and Synchrotrons will be the leading players. 17 Synchro for pdf 18 27/05/03 17:28 Page 18 Synchro for pdf 27/05/03 17:28 Page 19 THE FUTURE 1. MORE INTENSE SOURCES Today’s Synchrotrons and FEL are so powerful that they defy imagination. However, this does not mean that progress in this area has come to a halt, as amazing new sources are foreseen, with many new opportunities. Consider, for example, the equivalent heat flux of synchrotron light beams. Current sources, such as Elettra and Bessy II, are roughly comparable to the interior of a rocket nozzle. This means that they are ten times above a nuclear reactor core, and only 7-8 below the surface of the Sun! New synchrotron sources, such as the Swiss Light Source, will be even more powerful. Synchrotron light (left) challenges the Sun (right): the thermal equivalent of a synchrotron source is not much lower than that on the Sun’s surface! FEL are approaching an even more radical revolution. For many decades, researchers have dreamed of “X-ray lasers”. This dream is now close to reality. One major obstacle in building an X-ray laser is the optical cavity. In a visible or infrared laser, the cavity, formed by two mirrors, encloses the active medium enhancing the laser action. However, no mirrors exist for X-rays so no optical cavity can be constructed. Therefore the laser action must be extremely effective, with no need for cavity enhancement. In a Free-Electron Laser, the required effectiveness can be reached with a mechanism called “Self-Amplified Spontaneous Emission” (SASE). This mechanism requires precise handling of the electron beam, by a very powerful and sophisticated linear accelerator (LINAC) and by a “wiggler”. The SASE concept is under test to see how far it can be extended to short wavelength. If X-ray wavelengths are reached, a SASE FEL will produce ultrarapid X-ray bursts with unprecedented peak brightness. The peak brightness could in fact increase by more than ten orders of magnitude with respect to the most powerful synchrotrons. These novel sources would open up many new research opportunities, however they would not replace synchrotrons. Consider the analogy with continuous (CW) lasers and pulsed lasers. The latter emit very powerful, short pulses used for many applications, but cannot be used for equally important experiments requiring CW light. The projected European scenario must then include synchrotrons, as well as pulsed FEL. European users will thus have access to the most suitable source for each specific application. Europe is at the forefront of progress in X-ray sources. Laser-like devices based on the “Self-Amplified Spontaneous Emission” (SASE) mechanism could soon boost the peak output by many orders of magnitude. This is an image of the construction work of the TESLA instrument at HASYLAB (Hamburg). TESLA is designed to test the SASE concept. 19 Synchro for pdf 27/05/03 17:28 Page 20 Several areas of synchrotron-based research are rapidly expanding, and the demand for synchrotron beamtime is increasing. The expansion is demonstrated, for example, by the exponential growth in the number (vertical axis) of macromolecular structures deposited each year (horizontal axis) at the Brookhaven Protein Data Bank. Most of the structures are now solved using synchrotrons at least in the final stage. Europe’s response to the increasing demand for synchrotron beamtime: building new facilities – like the new high-brightness Bessy II Synchrotron in Berlin shown here – and opening them to transnational users with the help of the EC’s Access Programme. 20 Synchro for pdf 27/05/03 17:28 Page 21 2. INCREASED VARIETY OF USAGE When synchrotron light research started in the 1960’s, no one predicted its future impact. The USA, a pioneering country in this domain, could not guarantee that it would be used by more than four different research groups and projections in Europe were similarly conservative. These proved to be complete underestimates: American and European Synchrotrons are used every year by tens of thousands of groups. The reasons behind this growth are now quite clear. Electromagnetic waves are a truly basic tool for exploring the physical world. This tool is not confined to one discipline, but is universally used in all branches of science and technology. Synchrotrons and FEL produce the best possible electromagnetic waves in two key spectral domains: X-rays and infrared light. As a result, experimental researchers in many different disciplines use them. Multidisciplinarity is resulting in a strong increase in the number of potential and actual users of Synchrotrons and FEL. In the early stages of synchrotron light research, most users were atomic, molecular and solidstate physicists. The situation is entirely different now. Physics is a minority area, balanced by other prominent disciplines, with chemistry and biology at the forefront. Also, new areas like medical research, industrial fabrication and environmental studies are growing rapidly. The second growth factor mentioned earlier was the explosive increase of synchrotron-based macromolecular crystallography. This requires the use of synchrotron light for the long-term, systematic, study of tens of thousands of systems. Synchrotron-based research reaches new domains and new users: these X-ray micrographs, produced by the Bessy facility, may help the efforts to find a new vaccine for malaria. The exponential increase in demand has stimulated new construction projects such as the Swiss Light Source, Anka in Germany, Siberia II in Russia and Diamond in the UK. However the demand will continue to outstrip the available beamtime so regrettably synchrotron laboratories must reject many excellent proposals. New sources and new research facilities are needed. Furthermore, we must guarantee optimum use of all European facilities, beyond national barriers. This is a key objective for the EC “Enhancing Access to Research Infrastructures” programme and for the Round-Table’s coordinating activity. 21 Synchro for pdf 22 27/05/03 17:28 Page 22 Synchro for pdf 27/05/03 17:28 Page 23 EUROPEAN COORDINATION 1. TRANSNATIONAL USAGE The demand for synchrotron beamtime is so high that most individual European countries cannot meet the needs of their national users. Effective solutions have been implemented in two directions. First, the construction of the pan-European ESRF laboratory in Grenoble. Second, the EC transnational access programmes. Using sources beyond national boundaries is an old tradition of Synchrotron and FEL research. Users systematically travel to facilities in other countries and other continents, as required by their research needs. This is due in part to the world-wide scarcity of beamtime: researchers go wherever beamtime is available. But there is a second important factor: each Synchrotron and FEL source is a rather unique facility. The source characteristics and the available instrumentation change from facility to facility. In many cases, a specific application requires a specific laboratory. Users must travel to the best source for their research, no matter where it is geographically located. This tradition of transnational access has very positive aspects. Forced to leave the narrow boundaries of their home laboratories, the users are exposed to a wealth of new results and new ideas. Synchrotrons and FEL laboratories are exceedingly fertile breeding grounds for new science and technology. However such transnational access cannot be taken for granted. Outsiders may see many users from other countries at their own national facility, and wonder who is paying the related costs. This may lead to a simplistic but very negative measure: user fees. But, what is negative about user fees? The answer is well known to all scientists: every time research funds change hands there is an administration cost (“overhead”) which decreases the money really spent for research. This clashes with practical problems. Many interested users do not have the resources to travel to facilities in other countries and support their activities there. National facilities do not have the resources to serve the particular needs of transnational users. In European Union, the solution is provided by the EC access programmes. By means of the 2nd, 3rd, 4th and 5th Framework Programmes, the European Commission has taken very effective action based on the specific programmes “Large Installation Plan” (1989-91), “Human Capital and Mobility” (1992-94), “Training and Mobility of Researchers” (1994-98) and the present “Improving Human Research Potential” (1998-2002). For Synchrotrons and FEL, individual contracts were established with an increasing number of national facilities. The corresponding funds covered the travel and lodging expenses of transnational users and the facility expenses arising from transnational use. In addition, special contracts enabled facility consortia to jointly develop instruments of common interest, which increase or substantially improve the transnational access. The impact of all of the aforementioned EC programmes has been strong, broad and very positive. They have transformed the idealistic, theoretical, notion of “open doors” into a solid reality and at the same time they also stimulated many novel forms of European cooperation. Above all, by means of the SR and FEL Round-Table they have transformed a loose group of national facilities into a superb pan-European integrated system for science and technology. Overhead rates may be rather low in some institutions, but range up to the typical 35-50% university level in the USA and to the realistic 120-150% level charged by some private companies. Whatever the overhead, every money transfer causes an unnecessary waste. Yet, the menace of user fees always seems to be around the corner. The best way to avoid it would be the traditional and wise policy of reciprocal open doors. In the case of EC countries, member states open up, to a certain extent their national facilities to transnational users without any fee. The compensation for each “donor” state is the open use by its own scientists of other facilities in other countries. The management is simple and the waste is eliminated. The advantages of “open doors” are quite obvious, but this policy remains vulnerable. It is often the target of unjustified political attacks. Its survival depends on the continuing consensus of participating countries. Above all, the “open doors” policy must be a reality not just an ideal. Reciprocal open access to national facilities is an excellent way to make good use of research money – and to enable transnational users to obtain advanced results like this photoelectron diffraction pattern produced by Elettra. 23 Synchro for pdf 27/05/03 17:28 Page 24 Circular polarization is the subject of a successful EC-supported collaboration involving several European Synchrotrons. The image shows an electromagnetic elliptical wiggler source of circularly polarised light. The Round-Table coordinates synchrotron sources as well as Free-Electron Lasers, such as this advanced source at the FELIX instrument of the FOM laboratory in the Netherlands. 24 Synchro for pdf 27/05/03 17:29 Page 25 2. THE “ROUND-TABLE” History Convincing everyone of the validity of the “open door” policy for the European system of Synchrotrons and FEL is not a trivial task. The EC support is extremely effective in promoting new experiments and new collaborations. Nevertheless, some outsiders may superficially believe that it is just more money for “big science”. This is very far from reality, but even an unjustified negative image can cause a lot of damage. However this can be countered in two ways. Bradshaw (then director of Bessy) and the late John Fuggle (of the University of Nijmegen) took the initiative to organise three seminal ECsupported symposia in Berlin, Athens and Madrid, to debate the hot topic “VUV/XUV Synchrotron Radiation – Future Developments in Europe”. Shortly afterwards, the Synchrotron Round-Table was born. In subsequent years, the Synchrotron Round-Table activities became well established, in particular thanks to the illuminated action of the first Round-Table Coordinator Ian Munro, who was also the director of the Daresbury Synchrotron. The basic idea was quite simple: all facilities receiving EC money for transnational use agreed to participate in a coordinating body, the Round-Table, together with representatives of the user community and of other Synchrotron and FEL centers. The immediate objectives were: (1) to improve the facility service to users; (2) to reciprocally illustrate the use and impact of EC access support; (3) to facilitate exchanges; (4) to identify and eliminate, or prevent, waste and duplication; (5) to identify and promote novel ways for transnational cooperation. The facts prove that such a bottom-up approach is extremely successful. So successful that, as was already mentioned, it now constitutes a useful model of EC coordination. First of all, scientists and the general public must be made aware of the real nature of these programmes. They should realise that the research supported, although using big centralised instruments, is not “big science”. Most Synchrotron and FEL user groups are small University teams and have limited resources. Part of their research is performed in their home laboratories. Travelling to a centralised facility for special experiments does not change the “small-science” nature of their activities, but it gives them access to extraordinary additional opportunities. In addition, these visits provide the groups with an opportunity to break out of the boundaries of their home institutions, find new ideas and initiate new collaborations. The best definition of Synchrotron light and FEL research is, “small science at large shared facilities”. Secondly, the optimisation of the use of the EC’s support for open-door access must guarantee that there is neither waste nor duplication. This is not an easy task, because each facility needs to preserve its independence. The Round-Table was developed as a simple and effective solution to this problem. The solution was developed by the scientists directly concerned rather than imposed from above. In 1989, while the European Research Council was close to the adoption of the “Large Installation Plan”, Alex 25 Synchro for pdf 27/05/03 17:29 Page 26 Activities How does the Round-Table achieve its ambitious objectives? To understand this point, we must see a bit more in detail how the Round-Table operates. Its activities fall into three different domains: 1. Providing a Forum for a European-level discussion among Synchrotron and FEL users, the facilities’ management and other European facilities in the same field; 2. Providing up-to-date documentation on Synchrotron and FEL activities, for experienced and potential users and for anyone interested in these topics; 3. Supporting specialised workshops and other initiatives to help users and facilities to develop new transnational cooperation activities. The “forum” role is the oldest mission of the Round-Table. Once a year – or more often if required – representatives of both the users and the operators of European Synchrotrons and FEL convene at one of the facilities. They present data on the EC-supported use of national laboratories, including new initiatives for instrumentation and beamlines. By comparing data, facilities can improve their use of EC funds. Where there is duplication this can be openly debated and eliminated. The discussion is both informal and to the point, therefore it is very effective. Round-Table meetings are quite unique with respect to other opportunities for interaction such as professional conferences. First of all, they are “full immersion” events entirely dedicated to the exchange of ideas, which constitutes their primary objective. Second, they involve the entire body of facilities in Europe and official representatives of their users, rather than an arbitrary subset. Third, they are regular rather than sporadic events, so that new initiatives are not merely stimulated but also monitored and if necessary corrected. In a sense, the difference between Round-Table meetings and other interaction opportunities is like that between the official meetings of a company shareholders and the interactions between individual shareholders at social events: both are important, but the first is truly essential. The documentation task – which is the second activity area of the RoundTable – is interactively managed through the Daresbury and Elettra WWW homepages. The foundation is a comprehensive databank including all of the Synchrotrons and FEL, both in Europe and in the rest of the world, with detailed data on instrumentation and activities. Although the databank is interactively updated by the facilities themselves, “external users” can extract data concerning the present and foreseeable use of Synchrotron light and FEL. This is an extremely important point because strategic research decisions at the European level cannot be based on arbitrary opinions or guesses. The Round-Table can provide expert advice based on 26 Round-Table documentation is provided on the net by the Daresbury laboratory: entry point. The documentation concerns synchrotrons, FEL and macromolecular crystallography facilities in Europe and in the world. Synchro for pdf 27/05/03 17:29 Page 27 facts, guiding such debates towards reality. Such advice has been provided in several cases as an input to the assessment of the impact of new Synchrotron and FEL projects. The need for documentation is particularly important at the present time. The spectrum and quantity of FEL and synchrotron activities is changing dramatically. New trends like the explosive growth of synchrotron-based crystallography could not be predicted. But the Round-Table did warn all concerned parties at an early stage, and this was made possible by its continuous monitoring of the situation. The Round-Table documentation is also important for constructive interactions with other organizations, which are responsible for monitoring and planning research. Constructive interactions of this kind have included, for example, the Megascience Forum of the Organisation for Economic Cooperation and Development and the European Science Foundation. The third, and possibly most important aspect of Round-Table activity, is identifying directions in which new transnational cooperation would be desirable and this is in line with the philosophy of EC Concerted Actions. The necessity for action is quite clear in the case of Synchrotron and FEL laboratories, since several facilities, and/or user groups, often share the same technical problems. The “open door” policy would be to a large extent meaningless without the optimisation of resources through transnational cooperation. The Round-Table must therefore provide effective ways to identify, trigger and monitor cooperative activities. Some of the Workshops supported recently by the Round-Table • “Characterisation of the Photon Beam Emitted by the VUV SASE-FEL” at DESY (HASYLAB 1998) • “Current Development of FEL” (Max-Lab 1998) • “Modern Developments in the Field of VUV Low-Energy X-ray Optics for Synchrotron Radiation” (BESSY 9198). • “Focused Monochromators” (SLS-Daresbury 1999). • “Updating the Scientific Case for the SASE-FEL Under Construction at DESY” (HASYLAB 1999). • “X-ray Structure Solution on line: Implications for Structural Genomics” (EMBL Hamburg 1999). • “Synchrotron Radiation in Archaeometry” (SLS- Daresbury 1999). • “Optics for Third Generation Sources” (BESSY 1999). Some of the Schools supported recently by the Round-Table • European Synchrotron Radiation Society School (1999) • Santa Margherita di Pula Synchrotron Radiation School (1999) The main practical tools are specialised workshops for which partial RoundTable support is provided. These workshops are specifically dedicated to initiatives where transnational cooperation appears to be both possible and desirable. The decisions about sponsoring specific workshops are made collectively by all of the users’ and facilities’ representatives, based on the documentation presented by the workshop organisers. In particular, the documentation must show that the proposed topic can indeed lead to desirable cooperation between EC countries. • Hercules School on Synchrotron Radiation and Neutrons (Grenoble 1999 and 2000). Quite recently, the Round-Table also decided to support postdoctoral schools that prepare the new generations of European Synchrotrons and FEL users. This decision has already been implemented, for example, by providing partial support to the 1999 “Hercules School” in Grenoble. 27 Synchro for pdf 27/05/03 17:29 Page 28 Results The Round-Table is basically a service instrument to facilitate and monitor transnational cooperation and access in Europe for Synchrotron and FEL activities. Therefore, any assessment of transnational cooperation and access activities is also, indirectly, an assessment of the Round-Table. Such an assessment must rely on facts. An excellent data source for transnational cooperation and access is the “1998 EC Survey of the Users of Large-scale Facilities”. The survey revealed the dramatic evolution of the Synchrotron and FEL activities in Europe (as in the rest of the world). A few years ago, they were dominated by physics with a minority role of chemistry. Physics is now a minority area (46% of European users), with a strong role of chemistry (28%) and biology (18%), plus smaller percentages for engineering and other areas. The present trends accentuate this evolution, projecting biology as the leading area in the future (see figure). other biology physics chemistry Distribution by discipline of EC-supported access to Synchrotron Sources and FEL (1998 survey). These trends are in harmony with the strongly multidisciplinary character of the Round-Table and with its increasing attention to biology. The RoundTable members include the European Molecular Biology Laboratory (EMBL, Hamburg and Grenoble outstations). As a general philosophy, we strongly believe that multidisciplinarity is extremely good for Synchrotrons and FEL. The survey clearly demonstrated that EC support for transnational access paves the way to very many experiments and results which would have been otherwise impossible. An overwhelming majority (84%) of Synchrotron and FEL users stated in fact that the EC access support was essential for their experiments. Furthermore, the large majority of the supported users (78%) are satisfied of the overall service provided by the host facilities. The essential EC access support yielded a large number of scientific results and publications (on the average, 5.5 per users). As to the issue of women scientist promotion, there is ground for optimism. True, the access of women scientists is still below acceptable levels. But the percentage of women among Synchrotron and FEL users in Europe (28%) is much higher than for other types of facilities, and steadily improving. The EC access support is particularly important for young users. Approximately 2/3 of the benefiting scientists is below 39 years of age, and more than 1/3 is postdoctoral fellows and doctoral candidates. 28 The EMBL participation in the Round-Table (with its Grenoble and Hamburg outstations) reflects the growing importance of biology in synchrotron research. Synchro for pdf 27/05/03 17:29 Page 29 The survey also clarifies the user motivation for transnational access. In many cases, users travel to a foreign facility simply because there is no similar facility in their own country. But this is not always true: many ECsupported scientists are from countries with an excellent synchrotron infrastructure, like Germany and the UK. The motivation is to find the best possible instruments for their research. No single facility or country can develop all types of beamlines and instrumentation, therefore transnational access is a necessity for many experiments. We should note that such statistical data, however positive, cannot possibly convey the entire message about the importance of the EC access support, nor that of the Round-Table coordination. Each one of the experiments that are made possible by this support is a fascinating story, rich of scientific as well human aspects. During the 10-year celebration meeting in Paris, many such stories were presented. The success of the EC access programmes and, indirectly, that of the Round-Table can also be illustrated by the corresponding list of talks (see list below). In addition to transnational access, the EC also supports cooperative projects for new instrumentation of common interest, in particular instrumentation for transnational users. The resulting construction of instruments by several facilities in different EC countries is one of the most tangible results of transnational cooperation. And one of the areas in which the “seeding” and monitoring role of the Round-Table is most important and most visible. Several recent examples can be mentioned: projects on detectors and beamline optics, those concerning circular polarization and its standardized measurements, the programme for the development of new storage-ring based FEL sources for the ultraviolet light, the collaboration for networkbased management of user offices, and others. In each one of these cases, the essential impact of the preliminary and follow-up actions of the RoundTable is quite evident. For example, much such transnational collaboration are prepared and facilitated by Round-Table-supported workshops and by collegial discussions within the Round-Table framework. These actions make it possible to identify the most promising instrumentation topics for which transnational cooperation is needed. They bring together the interested parties for a rapid decision on the actual cooperation, assure the overall consensus of the European users and facilities, and avoid duplications, Last but not least, the Round-Table forum allows all interested parties – and not just a subset of users and managers – to monitor the progress of each collaboration project, to be informed of its results, and able to participate to their exploitation. The project thus really becomes a trans-European resource. Meeting to celebrate 10 years of European Synchrotron Radiation Research LIST OF TALKS Gerard Bricogne: Progress on the Phase Problem for the Determination of Structures Miquel Coll: MAD Phasing of the PhoB Protein and the DNA Decamer d(CCGGACCGG) Enric Chantler: Ultra Structural Changes in Capacitating Human Sperm Visualized in X-rays Peter Cloetens: Hard X-ray Coherent Imaging Paul Loubeyre: The Structure of Ice Under Very High Pressure Paolo Scardi: Structure of Thin Film Sensors by Glancing X-ray Diffraction Peter Laggner: Supramolecular Reactions and Phase Transformations: Real-time SWAX Ronald Imbihl: Spectromicroscopy of Chemical Waves on Catalytic Surfaces Maria-Carmen Asensio: Heterogeneous Catalysis and Adsorbate Structure Determination Using Photoelectron Diffraction Robert Feidenhans: Structure of Metals on Semiconductor Surfaces Enrique Garcia Michel: Origin of the Surface Phase Transition in SnGe(111) and Pb/Ge(111) Wolfgang Felsch: Magnetic Dichroism at LURE DCI and SUPER-ACO: Probing Cerium in Highly Correlated Multilayer Structures Giorgio Rossi: Time Resolved Surface Magnetometry in the Nanosecond Scale Using Synchrotron Radiation Patrick Mc Nally: Synchrotron X-ray Topography Applied to the Monitoring of 0.25 Micron CMOS Integrated Circuit Fabrication Franz Schaefers: Circular Polarization: Instrumentation Developments Francisco J. Balta Calleja: Time Resolved X-ray Studies of Structure Development in Polymers Francesco Sette: Inelastic X-ray Scattering to Study the Atom Collective Dynamics at High Frequency Benedikt Jean: Medical Studies with IR-FELs C.R. Pidgeon: Lifetime and Lifetime Design of Low-dimensional Semiconductors with Infrared picosecond FELs André Peremans: Development of Surface SFG Spectroscopy with FELs and Ancillary Lasers Maria Novella Piancastelli: Electron Decay Processes in Core-excited Molecules Studied Under a Resonant Auger Raman Condition 29 Synchro for pdf 27/05/03 17:29 Page 30 As the field grows rapidly, the need for European-level access to Synchrotrons and FEL increases, together with the importance of the RoundTable coordination. Protein crystallography is the most prominent factor of this increase, but other important elements should be taken into account. Coordination and access beyond the EC boundaries also constitute a challenge. The problems of open access are in fact common to all fellow scientists in the entire world. Many European users travel to the USA and to the Far East for their experiments. Conversely, European facilities welcome users from all over the planet. The entire field of Synchrotron light and FEL may in fact be heading towards a revolution, and the European strategy must be tuned accordingly. Besides crystallography, the most probable and most interesting and revolutionary elements are: This suggests that the models of EC access support and Round-Table coordination could be exported beyond the EU boundaries. The first objective could be the integration of European facilities outside the EU: Switzerland, Central Europe, Russia, and then also the USA and Japan. • The use of coherence, in particular for radiology. As we have seen, new radiological techniques are made possible by the superior quality of the new synchrotrons. If synchrotron radiology become a routine diagnostic tool, both the development of new sources, and their use, will radically change, and dramatically increase. • Industrial fabrication in the areas of microelectronics and micromechanics. The first area is a “standby” technology, waiting and ready for its window of use. International microelectronics leaders like IBM and Sematech dominate this field, but Europe also needs it for its own microelectronics production. Micromechanics is a wide open field with Europe at the forefront. A significant level of use for industrial microfabrication would once again revolutionise the strategic scenario for synchrotron activities. The Round-Table, a good idea conceived ten years ago by scientists and for scientists, could thus become a model solution for crucial problems affecting science all over the Earth. It certainly worked in Europe for more than ten years, enhancing the use of human and material resources, and facilitating many results in science and technology. Therefore, we should make an effort to explain its simple and effective common-sense philosophy to our colleagues in other countries and in other disciplines, with no boundaries whatsoever. Looking to the future 30 • Environmental research. Synchrotron and FEL-based microscopy, spectroscopy and spectromicroscopy are very powerful techniques for the early detection of trace contamination. Tests in ecological research have already produced excellent results. Thus, the future use of Synchrotrons and FEL in environmental research and testing is likely to significantly increase. • New sources. The quest for better sources is not over. Exciting new ideas are under consideration and development. The Round-Table is alert about these opportunities, and about the corresponding needs for transnational access and cooperation. We can propose two examples. First, the future commissioning of the Swiss Light Source (SLS), which will surpass the coherence and brightness performances of all present medium-energy synchrotrons. Second, the use of SASE-based FEL for the emission of ultraviolet and X-ray pulses with unprecedented peak brightness. We specifically note the SASE tests at HASYLAB within the TESLA project. A classic example of European transnational cooperation in the domain of synchrotron instrumentation: the collaboration of Max-Lab, Bessy and Elettra on measurements of circular polarization. The figure shows a beamline under construction at Elettra. The new synchrotrons emit light with laser-like coherence in a portion of their spectrum. The applications of coherent X-rays are rapidly expanding. The image shows a nice example: the sharp diffraction fringes produced by X-rays illuminating a microscopic object. Figure courtesy of E. Bauer. Synchro for pdf 27/05/03 17:29 Page 31 ANNEX 1 ROUND-TABLE MEMBERSHIP User Representatives: Keith Wilson (EMBL.Hamburg and University of York) Johann Turkenbourg (University of York) José Martin-Gago (Instituto Ciencia de Materiales CSIC, Madrid) Peter Laggner (Austrian Academy of Sciences) Petra Rudolf (LISE, Namur) Seppo Aksela (University of Oulu) Member Facilities: Sincrotrone Trieste SCpA (Elettra) S. S. 14, km 163,5, Basovizza I-34012 Trieste, Italy Homepage: www.elettra.trieste.it Foundation for Fundamental Research on Matter (FOM) FELIX Free-Electron Laser Institute for Plasma Physics “Rijnuizen” Edisonbaan 14 NL-3430 BE Nieuwegein, The Netherlands Homepage: http://www.rijnh.nl/departments/laser/felix/user/user.html CLIO LURE B. P. 34 Centre Universitare Paris Sud – Bâtiment 209 D F-91898 Cedex Orsay, France Homepage: http://www.lure.u-psud.fr/clio/clio_eng.htm Berliner Elektronenspeicherring-Gesellschaft für Synchrotronstrahlung m.b.H. (BESSY) Geb. 14.51, Albert-Einstein-Straße 15 D-12489 Berlin, Germany Homepage: http://www.bessy.de/ MAX-Laboratory Lund University P. O. Box 118 Ole Römersvag 1 S-221 00 Lund, Sweden Homepage: http://www.maxlab.lu.se/ Laboratoire pour l’utilisation du rayonnement électromagnétique (LURE) – CNRS B. P. 34 Centre Universitare Paris Sud – Bâtiment 209 D F-91898 Cedex Orsay, France Homepage: http://www.lure.u-psud.fr/ Institute for Storage Ring Facilities Aarhus (ISA) University of Aarhus Ny Munkengade, Bygn, 520 DK-8000 Aarhus C, Denmark Homepage: http://www.isa.au.dk/ Synchrotron Radiation Department, CLRC (SRS-Daresbury) Keckwicjk Lane, Daresbury WA4 4AD Warrington, UK Homepage: http://srs.dl.ac.uk/index.htm ANKA – Forschungzentrum Karlsruhe GmbH Projectgruppe Forschung und Entwicklung mit Synchrotronstrahlung (FES) P.O. Box 3640 D-76021 Karlsruhe, Germany Homepage: http://www.fzk.de/anka/ Hamburger Synchrotronstrahlungslabor (HASYLAB) DESY Notkestrasse. 85 D-22603 Hamburg, Germany Homepage: http://srs.dl.ac.uk/index.htm Swiss Light Source (SLS) Paul Scherrer Institute CH-5232 Villigen PSI, Switzerland Homepage: http://www1.psi.ch/www_sls_hn/ European Molecular Biology Laboratory (EMBL) Hamburg Outstation Building 25A Notkestrasse 85 D-22607 Hamburg, Germany Homepage: http://www.embl-hamburg.de/ SRS Daresbury MAX-lab Hasylab SLS European Molecular Biology Laboratory (EMBL) Grenoble Outstation EMBL Grenoble Outstation c/o ILL, BP 156 F-38042 Grenoble Cedex 9, France Homepage: http://www.embl-grenoble.fr/ ANKA EMBL Grenoble European Round-Table for Synchrotron Radiation and Free-Electron Lasers Elettra BESSY ISA CLIO EMBL Hamburg FELIX LURE 31 Synchro for pdf 27/05/03 17:29 Page 32 European Commission Research infrastructures Synchrotron Light and Free-Electron Lasers – Ten years of transnational research in Europe by Professor G. Margaritondo Luxembourg: Office for Official Publications of the European Communities 2000 — 31 pp. — 21 x 29.7 cm ISBN 92-828-8506-2 Synchro for pdf 27/05/03 17:29 Page 33 15 Over the last 10 years, the European Community research infrastructure programmes have made a major contribution to the fields of synchrotron radiation and free-electron lasers. Community support has been primarily allocated to scientists so that they could carry out experiments at research infrastructures in a different European country. OFFICE FOR OFFICIAL PUBLICATIONS OF THE EUROPEAN COMMUNITIES L-2985 Luxembourg ,!7IJ2I2-iifagc! CG-25-99-352-EN-C One in the series of brochures to highlight the contribution made by the Community research infrastructure programmes, this publication is the outcome of a meeting held in May 1999 to celebrate the 10th anniversary of the creation of the European Round-Table on Synchrotron Radiation and Free-Electron Lasers. It contains a description, based on the presentations given at the meeting, of the past, present and probable future of X-rays and their scientific uses. This publication will be of interest to both those in the field and those who are interested in becoming involved in transnational research.