Attendees' Index
UK Attendees' Index
China Attendees' Index
Andrew Desbois 2
Andrew Truman 3
Chris Dowson 4
David Aanense 5
David Gally 6
Elizabeth M H Wellington 7
Hayley Macgregor 8
Helen Lambert 9
Ian Donald 10
Ian Gilbert 11
James Barlow 12
John Callan 13
Jonathan Read 14
Lorna Paton 15
Mark Enright 16
Mark Holmes 17
Mark Woolhouse 18
Mike Sharland 19
Minakshi Bhardwaj 20
Nicola J Williams 21
Paul Barrow 22
Paul Langford 23
Paul Williams 24
Peter Taylor 25
Pradeep K Malakar 26
Sharon Peacock 27
Shona Hilton 28
Stefan Elbe 29
Steve Hinchliffe 30
Thamarai Schneiders 31
Timothy Walsh 32
Xiaodong Zhang 33
ADong Shen 35
Baoli Zhu 36
Cai-Guang Yang 37
Debin Wang 38
En-Min Zhou 39
Fuping Hu 40
George Fu Gao 41
Haihui Huang 42
Hanchun Yang 43
Hui Wang 44
Huiqing Yuan 45
Jianping Xie 46
Juan Li 47
Ling Lu 48
Minggui Wang 49
Qunhong Wu 50
Shijun Ding 51
Xiaofang Wang 52
Xinglin Feng 53
Yang Wang 54
Yaoxing Chen 55
Yaoyu Feng 56
Ying Wu 57
Yonghong Yang 58
Yunsong Yu 59
Yuxing Ni 60
Zhiyong Zong 61
Zongfu Mao 62
I
UK-China AMR Workshop
UK Researchers’ Biographies
23 – 27th November 2015
1
Dr Andrew Desbois
Institute of Aquaculture, University of Stirling
Job Title:
Lecturer of Marine Biotechnology
Contact: ad54@stir.ac.uk
Areas of scientific expertise which are relevant to this call:
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Host-pathogen interactions in aquaculture settings, including characterising microbial virulence mechanisms and
innate immune defences.
Discovery and development of novel and alternative antimicrobial compounds and treatment strategies, including
those for application in aquaculture.
Optimisation strategies for antibiotic regimens in aquaculture through modelling and experimental approaches in the
environment and in vivo.
Mechanisms of antibacterial resistance, including that conferred by changes in cellular membrane composition.
Member of the UK Veterinary Medicines Directorate Fish Forum on Antimicrobial Resistance in Aquaculture.
Interests and potential opportunities to explore:
Greater than 90% of global aquaculture takes place in Asia and this form of food production has been associated with
high usage of antibiotics. Thus, aquaculture settings need to be considered when aiming to describe, characterise and
understand issues around AMR, especially given the opportunity for exposure of people to antibiotics, their residues or
resistant bacteria during production or consumption. I am flexible with respect to the research questions that I would be
prepared to address because the issues around AMR in aquaculture in Asia are not well described and few reliable data
are available. Thus, I am interested to understand aspects around controls on supply, use and disposal practices for
antibiotics, including which antibiotics are being used and the criteria in place to select these, and how the antibiotics are
obtained and used at the farm. Moreover, I would be interested to better understand resistance mechanisms at a cellular
level, including the presence and prevalence of AMR mechanisms in the field. Hence, this is a rich area for exploration
and I would be willing to play a role in any projects looking to include an aquaculture perspective.
2
Dr Andrew Truman
John Innes Centre
Job Title:
Project Leader
Contact: andrew.truman@jic.ac.uk
Areas of scientific expertise which are relevant to this call:
My research concerns the biosynthesis of antibacterial natural products made by bacteria. Over half of all clinically used
antibiotics are made by Actinobacteria, so they represents a rich source of antibiotic-like molecules. Our work is
particularly focussed on three aspects of natural product biosynthesis that are all relevant to the discovery and
development of alternative antibiotics: (a) engineering existing pathways to make novel compounds; (b) genome mining
for natural products with novel structures; and (c) modifying pathway regulation to both activate the expression of
otherwise silent gene cluster and to increase the quantity of molecules produced in low yields. To carry out this research
we regularly genetically modify Streptomyces bacteria, characterise the activity of biosynthetic proteins and employ
various high-resolution mass spectrometry-based techniques to analysis our sample sets.
Interests and potential opportunities to explore:
I am interested in identifying potential collaborators that can add value to my research on bacterial natural products. For
example, the assessment of biological activity/mode of action of antibiotics generated in my research group, or the semisynthetic modification of these compounds. Additionally, I am interested in identifying any opportunities where my
research expertise could add value to research projects from other groups, such as the genetic analysis/modification of a
bacterial natural product that has potent antibacterial activity.
Additionally, my group forms part of a wider collection of research groups at the John Innes Centre that all study
bacterial natural product biosynthesis, and I am interested in identifying any opportunities for collaborations that could
involve these microbiology groups.
3
Prof Chris Dowson
University of Warwick
Job Title:
Professor of Microbiology
Contact:
c.g.dowson@warwick.ac.uk
Areas of scientific expertise which are relevant to this call:
Molecular microbiology, biochemistry and structural biology of bacterial cell wall biosynthesis and protein biosynthesis,
developing novel reagents and assays with academia and industry to underpin HTS and antibiotic discovery. Delivery of
novel doctoral training programmes to underpin new antibiotic discovery
Interests and potential opportunities to explore:
Explore partnerships for research and training in fundamental science and antibiotic discovery.
4
Dr David Aanense
Imperial College London / Wellcome Trust Sanger Institute – The Centre for
Genomic Pathogen Surveillance
Job Title:
Director - Centre for Genomic Pathogen Surveillance, Wellcome Trust Sanger
Institute, UK
Senior Lecturer - Imperial College London, UK
Contact: d.aanensen@imperial.ac.uk
Areas of scientific expertise which are relevant to this call:
Genomic epidemiology and bioinformatics of bacterial pathogens. Molecular epidemiology, particulary with respect to
public health and global health focussed on microbial population biology.
The Centre for Genomic pathogen Surveillance at the Sanger institute is focussed on the provision of data and tools for
the global monitoring of antimicrobial resistance using whole genome sequencing (WGS). Large scale structured
pathogen surveys, along with whole genome sequencing and the open provision of such data through intuitive
interpretation software (via the web) provides methods to enable identification, risk assessment (eg AMR,
transmissibility) and ultimately monitoring and control of high risk pathogenic clones.
Tools developed include www.wgsa.net for shared analysis of genome sequences, www.microreact.org for intuitive
visualisation and exploration of datasets and www.epicollect.net for generic mobile data gathering.
At Imperial College, we are interested in the mathematical modelling of infectious diseases and the use of such
information for informing policy and control measures.
Interests and potential opportunities to explore:
I would be very keen to explore the utility of whole genome sequencing, in conjunction with existing or emerging
national networks of laboratories to understand the spread of antimicrobial resistance. Linking data within a region,
between regions and globally would allow us to monitor emergence and spread of high risk clones in a bacterial
population - Key to this would be focussing on antimicrobial resistance and using this information to produce rapidresponse clone-specific diagnostics for the ultimate prevention of spread. I would like to meet participants to discuss and
to establish collaborations that would lead to knowledge exchange and targeted plans to address the usefulness of WGS
within networks of laboratories.
5
Prof David Gally
University of Edinburgh
Job Title:
Professor of Microbial Genetics
Convenor of a Roslin Institute research programme on ‘Innate Immunity and Endemic Disease of Livestock’
Contact: dgally@ed.ac.uk
Areas of scientific expertise which are relevant to this call:
My main research interests are in the first two areas of the call:
1. I am engaged in research on species-specific carriage of AMR genes and the genetic context of AMR genes, especially
on plasmids and their potential to transfer to human pathogenic strains. E. coli is my main research organism working
with strains from livestock and companion animal species.
2. I have research on-going related to sequence-based prediction of bacteriophage resistance and susceptibility. Through
phage selection and improved delivery systems we aim to revisit the value of phage therapy and its use to treat MDR
infections. I also have collaborations selecting for small molecules that target the expression or function of important
bacterial virulence factors as a form of anti-virulence or pacification treatment.
3. I work on food safety vaccines, in particular in cattle, with the argument that adoption of more immune-based
approaches could reduce the use of antimicrobial agents. An extrapolation of this could be genetically engineered
production species with increased resistance to particular infectious agents.
Interests and potential opportunities to explore:
1. The agricultural use of antibiotics and assessing the impact of their use for emergence and maintenance of resistance in
human medicine.
2. Approaches to reduce disease burden and productivity in animals that may reduce the threat of MDR strains in the
human population.
6
Prof Elizabeth M H Wellington
University of Warwick
Job Title:
Professor, Director WESIC, Leader Environment Theme School of Life
Sciences
Contact: e.m.h.wellington@warwick.ac.uk
Areas of scientific expertise which are relevant to this call:
Research interest in the co-evolution of antibiotic resistance and biosynthesis in the soil and other environmental systems
with a focus on how the introduction of highly resistant bacteria to the environmental impacts on microbial communities.
I have conducted research into the ecology of antibiotic production for many years and discovered microbial ‘cheaters’
closely related strains which have retained resistance but have no biosynthetic capability. A strong current focus is the
fate and survival of antibiotic resistance genes (ARGs) in natural environments. Several routes of dissemination of ARGs
have been identified during research done over the past fifteen years and have included the addition of sewage sludge to
land, manure spreading and use as fertiliser, fish farming and the effluent from waste water treatment plants (WWTPs).
Interests and potential opportunities to explore:
I am interested in renewing research collaborations with Chinese scientists I have met at a number of international
meetings to gather support for research initiative into studying the impact of ARGs on the ecology of antagonism and coevolution of antibiotic biosynthesis and resistance in soil and other environments. This requires scientists who are both
interested in antibiotic discovery and antimicrobial resistance and have concerns about the environment as a reservoir for
the evolution of resistance and dissemination of ARGs to animals and humans. The key opportunities would be to
promote the above area of research and focus of environmental impacts of ARG spread in addition to how microbial
antagonism is affected. The latter is critically important in the rhizosphere where plants benefit from inhibition of fungal
pathogens via bioactive metabolites produced by their microbiome colonising roots. I am part of a BBSRC partnership
Warwick-CAS (Greg Challis PI) on exploiting microbial genomics and synthetic biology for discovery of novel
antibiotics.
The meeting will also help to improve my current knowledge of research expertise in China regarding these areas of
focus and establish who the key scientific innovators are currently. I wish to explore the range of ways in which I can
interact with these individuals and gain support for meetings, research exchanges and joint projects.
7
Hayley Macgregor
Institute of Development Studies, UK
Job title:
Research Fellow and Co-convenor, Health and Nutrition research cluster
Contact: h.macgregor@ids.ac.uk
Areas of scientific expertise which are relevant to this call:
Originally trained as a medical doctor in South Africa, I pursued further studies in Social Anthropology. Research
interests include the anthropology of development and rights, in particular the politics of aid and rights discourses in
global health; lay and informal health providers; the political economy of social protection policy; and kinship relations
and concepts of care and chronicity in responses to lifelong illness. I am also engaged in interdisciplinary research on
disease-environment interactions in the context of zoonotic disease emergence. I am the social science lead for a ZELS
programme called the Myanmar Pig Partnership with a focus on veterinary antibiotic use and the relationship to AMR.
Interests and potential opportunities to explore:
I am interested in the role informal and lay health providers in complex health systems and in critical examination of
programmes aimed at behavioural change. I wish to explore opportunities to expand research on the implications of
veterinary antibiotic use. IDS is developing work on AMR and my colleagues Gerry Bloom and Annie Wilkinson
authored a paper for the ESRC in Nov 2014. We have expertise in health systems and health markets.
8
Helen Lambert
University of Bristol
Job title:
Reader in Medical Anthropology
Contact: h.lambert@bristol.ac.uk
Areas of scientific expertise which are relevant to this call:
Medical anthropology; qualitative research methods; treatment-seeking behaviour; Asian medical traditions and health
cultures; plural health systems and treatment pathways; informal sector; public and professional perceptions of infection
and resistance; social science evidence for public health intervention design and evaluation
Interests and potential opportunities to explore:
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Developing interdisciplinary collaborations between scientists and social scientists for AMR research
Comparative AMR research in UK, China, India
Treatment pathways, formal and informal therapeutic practices relating to infection and antimicrobials
Social and cultural determinants of AMR
Methodologies to capture antimicrobial consumption patterns
9
Prof Ian Donald
University of Liverpool
Job title:
Professor of Psychology
Areas of scientific expertise which are relevant to this call:
I am a social and environmental psychologist with a broad social science background. I have worked extensively on
cross-disciplinary research with engineers, computer scientists, biologists, vets and medics. My main areas of expertise
are in identifying the factors underlying human behaviour, behaviour change, attitudes and attitude measurement. My
research has been conducted in a variety of significant substantive areas of societal importance. This has included
working with vets examining farmers’ behaviour and attitudes in relation to bovine TB. In particular this work looked at
the relationship between policy and regulation and behaviour. I have recently published a major DfT supported study of
transport mode choice, modelling the role of habit in relation to attitudes and behaviour. It is likely that understanding
habit will be of importance in examining the behavioural drivers of AMR.
I was the ESRC’s consultant in producing the research priorities for Theme 4 and authored the ESRC publication, AntiMicrobial Resistance: Behaviour within and Beyond the Healthcare Setting. I was also a member of the ESRC’s working
group on AMR, which led to the publication, Anti-Microbial Resistance: Setting the Social Science Agenda. I was a
member of the NERC assessment panel for stage one of theme 3 applications. I was also a member of Nesta’s advisory
group for the Longitude Prize 2014 on Antibiotic Resistance.
Interests and potential opportunities to explore:
My interest in this area stems from my previous involvement with the ESRC in the development Theme 4 of the joint
council initiative. Participating in these activities and drawing together a number of perspectives has given me the
opportunity to contribute to the AMR research landscape and linked me into an existing network of social scientists. As
part of my consultant role with the ESRC I identified the international priorities of the theme. I see the workshop in
China as a natural development of my involvement and feel it provides continuity and an opportunity to help shape the
international agenda in one of the most important AMR contexts globally. I feel that my general expertise,
multidisciplinary and international research background, along with the expertise and insight I have gained working with
the ESRC to date would allow me to make a significant contribution to the workshop.
I have conducted research with colleagues in China and Hong Kong and would welcome the opportunity to meet other
colleagues from China. In particular I would be excited to gain an understanding of the relevant issues within a Chinese
context. I would very much like to develop potential research projects that will provide innovative and well-informed
solutions to AMR and behaviour change.
10
Ian Gilbert
University of Dundee
Job title:
Areas of scientific expertise which are relevant to this call:
Interests and potential opportunities to explore:
11
James Barlow
Business School, Imperial College London
Job title:
Chair in Technology and Innovation Management
James Barlow has held a Chair in Technology and Innovation Management (Healthcare) at Imperial College Business
School since 2003. Since September 2013 he has also been Associate Director of Research and Evaluation for Imperial
College Health Partners. He was co-director of the Imperial College’s Innovation Studies Centre from 2003-2006. From
2006-2013 he led HaCIRIC, a major programme of research on the adoption, implementation and sustainability of
innovation in healthcare infrastructure systems.
James was educated at the London School of Economics (BA and PhD) and has previously held appointments at the
Science Policy Research Unit (SPRU, University of Sussex), the Policy Studies Institute and the University of
Westminster.
Much of James’ research and practice has been on the development and introduction of complex healthcare technologies,
as well as organizational and financial innovations such as public-private partnerships. He has published widely and has
been a member of many expert panels on healthcare innovation, both in the UK and internationally.
He is a member of the executive for the NIHR Northwest London CLAHRC and the Dept. of Health Policy Innovation
Research Unit. In September 2014 he was appointed President of the International Academic for Design and Health.
James has worked extensively with companies involved in the healthcare sector, including pharmaceuticals, medical
devices, ICT and construction. He has been a member of healthcare advisory boards for UK companies, and currently sits
on the advisory board for Guy’s and St Thomas’ Hospital Charitable Trust and. For more information see www.jamesbarlow.com and www.imperial.ac.uk/people/j.barlow.
12
Prof John Callan
Ulster University
Job title:
Norbrook Chair in Pharmaceutical Science
Areas of scientific expertise which are relevant to this call:
Our main interest is in the development of alternative approaches for the treatment of AMR infection, in particular the
use of Antimicrobial Photodynamic Therapy (APDT) and the related technique Antimicrobial Sonodynamic Therapy
(ASDT). We are also interested in the use of microbubbles in combination with low intensity ultrasound deliver to
antimicrobial agents to specific sites of infection and collaborate with Prof E Stride (Oxford University) in this area. In
addition we are also interested in the synthesis and evaluation of antimicrobial peptides.
I am also co-founder of the Northern Ireland AMR network (http://www.challengecluster.com/) that organises meetings
to promote discussion and identify collaborations between academics, industrialists, veterinarians and clinicians
throughout the province of Northern Ireland with a vested interest in combating AMR.
Interests and potential opportunities to explore:
We are keen to develop collaborations with groups in China that also have an interest in antimicrobial PDT / SDT. There
are only a few other groups in the UK working in this areas while in China there are a significant number. Therefore, it
would be very useful to meet with and identify potential collaborators with whom we could submit a joint proposal to
this call.
It is our belief that PDT/SDT has significant potential in the treatment of AMR, in particular for localised infection. As
such, we feel it should be included in the scope of this call and would therefore like to be present at the meeting to
comment on its potential.
13
Jonathan Read
Lancaster University / University of Liverpool
Job title:
Senior Lecturer in Epidemiology (Lancaster)
Areas of scientific expertise which are relevant to this call:
I am an infectious disease epidemiologist working at the interface of theory and interventions for communicable diseases.
My research interests include quantifying and modelling social contact networks, developing realistic mathematical
models of the transmission dynamics of infectious diseases, improving vaccination and intervention policies, and
understanding the epidemiology of respiratory viral pathogens. Pathogens studied include influenza, ebola, RSV,
Streptococcus pneumonia, rotavirus and norovirus. Much of my work has focussed recently on measuring and
understanding patterns of movement and interaction of people for the purposes of better parameterised models for
infectious disease forecasting. I have helped design and conduct epidemiological field work in several Asian countries,
including China.
Interests and potential opportunities to explore:
I am interested in the pattern of human interactions and mixing behaviour that contribute to the spread of AMR
organisms, particularly outside of healthcare institutions.
I see mathematical modelling as a key aspect in mitigating AMR emergence; no other framework can deal with the
diverse scales at which important factors thought to drive AMR emergence occur. As such, I would like to offer my
experience as a mathematical and statistical modeller to the workshop, with the aim of developing a coherent predictive
framework that different disciplines can contribute to synergistically.
I would also like to offer my experience in collaborating with Chinese colleagues and share the findings from our
fieldwork, particularly in our quantification of human social interactions networks, contact rates with animals and their
produce, and travel behaviours.
14
Lorna Paton
Scotland’s Rural College
Job title:
Farm Management Researcher
Areas of scientific expertise which are relevant to this call:
Expertise in animal health planning, usage of antibiotics at farm level within the ruminant sector and the government
policies and implementation at local, national and EU level. The focus of my current work is on farmer decision making
and behaviour change, I am also undertaking a part- time PhD that aims to better understand antibiotic usage on farms
and identify ways to improve efficacy leading to reduced overall usage of antibiotics.
SRUC has a long history of conducting agricultural research and disseminating results to farmers, policy makers and the
public. In the organisation over 30 of my colleagues from various research groups are interested in or currently working
within the field of antimicrobial resistance both in farmed/domestic animals and wild populations and as a result of this
work and work within our veterinary laboratories we have a vast amount of epidemiological historic samples and the
ability to collect and analyse animal and environmental samples through our network of contacts and clients.
Interests and potential opportunities to explore:
My interest in attending this workshop is to better understand global research into antimicrobial resistance and improve
the linkages between work on antibacterial resistance in human medicine and environment with the work we are doing
within the farm animal sector.
My personal contribution to the workshop will be to bring social economic aspects with particular reference to farm
management and farmer behaviour. The success of any farm focussed initiatives are reliant on farmer compliance and
uptake. This will only be achieved if the farm management aspects are integrated into projects from the initial planning
stage with farmers being true stakeholders in the initiative.
At an organisational level there is interest in increasing our work in antimicrobial resistance and to increase the linkages
with other groups working within the human and veterinary medicine field to maximise the benefits of a “one health”
approach.
15
Prof Mark Enright
Manchester Metropolitan University
Job title:
Areas of scientific expertise which are relevant to this call:
My research has focussed on the epidemiology and evolution of antibiotic resistant pathogens such as methicillinresistant Staphylococcus aureus (MRSA) and AMR Streptococcus pneumonia. I developed multilocus sequence typing
(MLST) schemes that were key in characterizing the global epidemiology of MRSA and AMR pneumococcal emergence
and spread. I was involved in several of the first major next-gen genomic sequencing projects on S. aureus and MRSA
evolution and I am currently working with bioMerieux (Lyons, France) on a large genomics / AMR project on a global
collection of AMR Pseudomonas aeruginosa, the first report of which will be published shortly. I have also worked in
industry for several years in the area of bacteriophage therapeutics for AMR pathogens and my current research includes
the development of novel phage therapeutics for staphylococcal infections and carriage. I am also involved in the
development of novel synthetic biology approaches to treat AMR resistant pathogens as a consultant and advisor to
Synthetic Genomics Vaccine Inc., La Jolla, United States. In addition I have worked on several projects examining the
efficacy of novel antimicrobial molecules, fabrics and surfaces – work which is a strength of microbiology research at
MMU.
Interests and potential opportunities to explore:
I am interested in attending the workshop in order to forge links and develop partnerships with Chinese researchers and
companies involved in microbial genomics / epidemiology, synthetic biology and phage and other alternative
antimicrobial therapeutics – rapidly growing fields in China. Several research groups including ones based in Shanghai
are active in the field of phage therapeutics for treating AMR infections and I think that collaborations based on the
genomics of host bacteria / phage interactions and preclinical and clinical studies of candidate therapeutics could be
beneficial to all partners and provide fruitful academic and business opportunities in China and the UK. I will be
representing MMU microbiology and I will describe our work on antimicrobial surfaces, novel materials, imaging and
pathogen biofilms.
16
Dr Mark Holmes
University of Cambridge
Job title:
Reader in Microbial Genomics & Veterinary Science
Area of scientific expertise which are relevant to this call:
The work in my group uses next generation sequencing (NGS), molecular biology, epidemiology and mathematical
modelling to look at both existing and novel mechanisms of AMR. We discovered the mecC gene in MRSA of animal
and human origin and have published papers characterising the novel PBP2a gene product. We use NGS to look at the
population structure of antimicrobial resistant pathogens, their evolution, and the transmission pathways of infection
between animals and people. We are currently using a chromosome conformation sequencing technique that generates a
much greater resolution of information obtained from metagenomes which enables us to associate AMR genes with the
individual bacterial species which harbour them. We are using this technique to look at AMR in both the culturable and
the non-culturable gut microbiome to investigate the dynamics of AMR within the microbiome. The majority of our
recent work has been in Staphylococci but we have also worked with ESBL E. coli and vancomycin resistant Enterococci.
Interests and potential opportunities to explore:
My interest is mainly in focus 1 and I am currently funded by the MRC to work on the dynamics of the transfer of
antimicrobial resistance genes within the microbiota of the gut in farm animals and people.
I am particularly interested in the opportunity to look at different agricultural systems and geographically separate
populations of farm animals. We already know that there are different lineages of livestock associated MRSA (LAMRSA) that predominate in China (compared to Europe & North America) and this presents an opportunity to compare
the genomes of LA-MRSA lineages in the UK and China to look for common features that may explain the broad host
species range of these lineages.
I am also interested in the broader issues facing livestock farming and the control of endemic disease using blanket
treatment with antibiotics. Developing an evidence base to support improved antibiotic stewardship is clearly an
imperative. I believe that multidisciplinary research including clinical research, epidemiology, microbial genomics and
mathematical modelling needs to be performed to generate this evidence both to identify where the greatest risks of
developing AMR lie and to identify the changes in husbandry/disease control strategies/human behaviour that are needed
to mitigate those risks.
17
Prof Mark Woolhouse
School of Molecular, Genetic and Population Health Sciences
Job title:
Chair of Infectious Disease Epidemiology
Area of scientific expertise which are relevant to this call:
Spatial and temporal patterns in the epidemiology of infectious diseases. Transmission of infectious agents between
humans and livestock. Design of surveillance systems and intervention strategies. Global governance of AMR.
Interests and potential opportunities to explore:
Sharing of ideas, information and data to improve our understanding of and response to AMR at a global scale.
18
Prof Mike Sharland
Institute for Infection and Immunity, St George’s University London
Job title:
Professor in Paediatric Infectious Diseases
Area of scientific expertise which are relevant to this call:
My main research interests are in the optimal prescribing of antimicrobials and antimicrobial resistance in neonates and
children. I set up and chaired the DG Sanco funded Antimicrobial Resistance and Prescribing in European Children
project (www.arpecproject.eu), which has kick started the development of paediatric Antimicrobial Stewardship
programmes across Europe. I have now set up and lead the Global Antimicrobial Resistance, Prescribing and Efficacy
Project (www.garpec.org), which is the only neonatal and paediatric focussed AMR surveillance programme. I co-chair
PENTA-ID (www.penta-id.org), the EMA’s recognised level 1 clinical trials network for all paediatric antimicrobial
research. PENTA-ID runs observational and interventional clinical trials in antimicrobials. I also run an academic
research unit in the UK, the Paediatric Infectious Diseases Research Group at SGUL, which conducts a range of studies
tackling AMR through quality improvement programmes and randomised trials, including CLAHRC, HTA and other
NIHR and charity funding streams.
I also Chair the DH’s Expert Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection
(ARHAI). I am developing an academic interest in the optimal design of national policy interventions to tackle AMR. I
am working with the DH to develop an international collaboration on assessing outcomes of national action plans to
combat AMR.
Interests and potential opportunities to explore:
I would be using the workshop to further develop our study design on understanding the behavioural aspects of
prescribing antibiotics for children in China. This includes the family’s understanding of fever and illness, the role of oral
and intravenous antibiotics and the influences on doctors’ choice of drug, dose, duration and decision to prescribe.
On behalf of the collaborative team, I would like to explore some of the potential influences on prescribing behaviour in
both the clinic and ward settings, including the role of guidelines, organisational hierarchies and team structures. I would
explore the feasibility of qualitative research approaches within the Chinese Children Hospital setting and the difficulties
of implementing change and assessing outcomes.
I would also be interested in discussing at a national level the formal policy interventions that are being taken forward
with ASP and IPC, including the Quality Indicator matrices being used, the process and outcomes that have been chosen
and their rationale and reproducibility.
19
Dr Minakshi Bhardwaj
Liverpool School of Tropical Medicine
Job title:
Post-Doctoral Research Associate
Area of scientific expertise which are relevant to this call:
I have a multidisciplinary background with qualifications in biological sciences (MSc, PhD), biomedical ethics and
public health (MPH). My expertise is in exploring ethical, legal and social issues arising in the international governance
of biomedicine and global health with particular focus on Asia. I use quantitative and qualitative methods in my work to
explore socio-economic determinants, cultural practices and moral values that shape health system governance, and
address gender and equity issues. My work has included comparative studies between developed and developing
countries on governance of new biomedical technologies (genomic databases, stem cell research etc), role of community
health workers to reduce maternal mortality, promote preventative services and health promotion in fragile health
systems (for example India).
I have recently started exploring ethical, legal and social issues emerging due to the rise in Anti-Microbial Resistance, for
example in patient and out- patient prescribing practices, evaluation of anti-microbial stewardship (type/load of
prescriptions at the hospital and community level and resistance), role of informal providers, hygiene and sanitation in
PHCs, maternal health and rate of antibiotic prescriptions during intrapartum care.
Interests and potential opportunities to explore:
I am interested in conducting comparative studies between different countries. I believe this opportunity provides me a
platform to comprehensively understand issues related to AMR in China, explore similarities and differences from other
countries (India, Malawi for example). I am interested in the epidemiology and social science issues to understand the
scale of the problem, level of understanding and different kinds of behavioural and clinical interventional approaches. I
am interested to develop collaborative work exploring antimicrobial stewardship issues such as prescribing practices and
AMR (in-patient/out-patient, formal/informal prescribers); role community health workers in health promotion/adherence
to medicine, resistance and maternal mortality; and different types of interventional approaches to improve AMR in
China.
20
Prof Nicola J Williams
Institute of Infection and Global Health, University of Liverpool
Job title:
Professor of Bacterial Zoonotic Disease
Area of scientific expertise which are relevant to this call:
Professor of Bacterial Zoonotic Disease with 15 years research experience on bacterial zoonoses (including antimicrobial
resistance) in wildlife, food and companion animal species, investigating reservoirs, survival in the environment, fitness
and transmission between animals and to humans, using a combination of conventional microbiology and molecular
biology and next generation sequencing.
I currently have a large portfolio of research on foodborne pathogens in poultry and I am involved in projects across the
EU, Kenya, Ethiopia and Thailand on Campylobacter and also AMR E. coli (in multiple food animal species), and I work
closely with industry and other stakeholders. Further current research is focused on the drivers for antibacterial use and
resistance, the impact of antimicrobials on the gastrointestinal microbiome and the role of the microbiome in
gastrointestinal disease.
Interests and potential opportunities to explore:
China is one of the largest producers of poultry and pork meat, to meet increasing demand due to a growing and more
affluent population, but also for the export market. This has resulted in the rapid industrialisation of both poultry and
pork production. Intensive production practices, however also increase reliance on antibacterials to maintain animal
welfare and health, selecting for antibacterial resistance. Furthermore, production practices may also influence
populations of microorganisms associated with food animals and their environment, and the routes by which they are
transmitted.
The farm and processing environments represents an interface between livestock and workers, providing an opportunity
for zoonotic transmission of foodborne pathogens and AMR. Traditional wet markets supplying meat may also represent
a significant public health risk, due to the provision of live birds for home slaughter, or animals prepared on site where
hygienic practices may be poor, however such markets may be supplied by smaller/backyard farms were antibacterial use
may differ.
I would be interested in the exploring opportunities to examine the impact of changing farming practices on driving
antibacterial use, AMR selection and transmission, and the public health risk.
21
Prof Paul Barrow
University of Nottingham
Job title:
Professor of Veterinary Infectious Diseases, Sub-Dean for Research and Business
Area of scientific expertise which are relevant to this call:
Enteric bacterial infections, Poultry Health, Collaboration with China Agricultural University for 10 years
Interests and potential opportunities to explore:
Exploration of link between antibiotic usage and transmission of bacteria and resistance determinants form livestock to
man through food chain and other routes
22
Prof Paul Langford
Imperial College London
Job title:
Professor of Paediatric Infectious Diseases
Area of scientific expertise which are relevant to this call:
Bacterial pathogenicity, vaccines and diagnostics for respiratory pathogens of animals (Actinobacillus pleuro pneumonia
(APP) and other Pasteurellaceae) and man (Neisseria meningitidis, Haemophilus influenzae, Mycobacterium
tuberculosis). In relation to AMR - emphasis is on resistance mechanisms and their spread (APP and other
Pasteurellaceae of animals) and development of antimicrobial peptides to treat tuberculosis, respectively. Also we have
developed and used high throughput whole genome transposon mutant based screens of bacteria (especially the
Pasteurellaceae), which are applicable to identifying novel antimicrobial targets.
Interests and potential opportunities to explore:
Over the last two years my group has, via initiation through a BBSRC Long Lasting (LoLa) grant, links with the Animal
and Plant Health Agency (UK) and a group in Singapore, been increasingly focussing on AMR. I see the workshop in
China as a valuable opportunity to identify collaborators with whom to have shared work programmes. My current
collaborators in the area of pig diagnostics and vaccines in China do not have an interest in AMR.
23
Prof Paul Williams
University of Nottingham
Job title:
Professor of Molecular Microbiology
Area of scientific expertise which are relevant to this call:
Molecular microbiology, bacterial pathogenicity, gene regulation, novel antimicrobial targets, quorum sensing, biofilms,
discovery and development of anti-virulence agents, biosensors, biomarkers of infection, discovery and development of
bacteria attachment-resistant surfaces for medical device applications.
Interests and potential opportunities to explore:
Development of novel antibacterial agents and smart materials for medical devices
24
Prof Peter Taylor
University College London
Job title:
Professor of Microbiology at UCL School of Pharmacy
My laboratory is dedicated to the discovery and development of new agents for the treatment of bacterial infections, the
identification of new targets for antibacterial drug discovery and the development of novel paradigms for the treatment of
bacterial infections based on the principle of pathogen disarmament by suppression of virulence and antibiotic resistance
machineries. One aspect involves enzymes with therapeutic potential that resolve severe, systemic bacterial infections by
stripping away the protective capsule; current activity in this area focuses on the capsule of Bacillus anthracis. Earlier
work on the capsule of the neuro-pathogen Escherichia coli K1 has broadened into investigation of the age dependency
of neonatal bacterial sepsis and meningitis, with emphasis on initial colonization of the gastrointestinal tract; this has
informed on novel approaches to the prevention of infection through supplementation of host factors such as the
protective GI tract mucin barrier. I also investigate novel approaches to the treatment of methicillin-resistant
staphylococcal infections based on modulation of beta-lactam resistance by catechingallates derived from green tea.
25
Pradeep K Malakar
Institute Food Research, Norwich
Job title:
Institute Food Research, Norwich
Area of scientific expertise which are relevant to this call:
Research at the Institute of Food Research (IFR) underpins the development of knowledge-led approaches, e.g.
quantitative microbial risk assessment (QMRA), for a greater understanding of the strategies that enable the survival,
transmission and virulence of bacterial foodborne pathogens in the food chain and host.
Our research focuses on the development of strong mathematical descriptions, and improved quantitative understanding,
for the hazards and risks that are associated with food consumption. The niche created for resistant foodborne pathogens
in the food chain from use and misuse of antimicrobials in agriculture is a concern.
Increasingly our research concentrates on the complex systems nature of food safety considerations, on a molecular
understanding of hazardous agents, in particular those hazards that are associated with bacterial agents, and on
stakeholder participation in food risk issues. Improved quantification of uncertainties, improved understanding of
complexities and stronger support for communication and management of food safety information are key areas of
research.
Expertize at IFR can assist risk managers or decision-makers in identifying specific scientific risk questions for
quantifying the significance of continued use of antimicrobials in Agriculture. Expertize at IFR should also bring the best
science to bear in providing answers, along with expressions of scientific uncertainty.
Interests and potential opportunities to explore:
It is estimated that approximately, 84,000 tons of antimicrobials is used in China for animal production. Comparatively,
UK use is approximately 400 tons. IFR is interested in investigating the impact of reduction of antimicrobial use in
animal production in China on the food supply chain. The Shanghai workshop will help IFR network with key academics
in China on strategies for reducing antimicrobial use, starting with the sub therapeutic use of antimicrobials in feed.
On 8th July, I was invited by the British Embassy in Beijing to attend an Agri-tech workshop organized by the embassy
(http://www.cittc.net/sites/english/forumTheme.html ). This event provided me with the opportunity to network with Dr
Anru Wang, deputy director of the State Key Laboratory of Direct-Fed Microbial Engineering. This laboratory is also
part of the Beijing Da BeiNong Science and Technology Group, a national livestock industry leader specializing in feed,
genetics, pig breeding, and livestock insurance. Dr Wang will visit IFR on 22nd September.
IFR intends to further develop a research proposal on impacts from reduction of antimicrobial use on the food supply
chain locally and internationally, collaboratively with Dr Wang and interested UK and Chinese counterparts during the
Shanghai workshop.
26
Sharon Peacock
London School of Hygiene and Tropical Medicine
Job title:
Director, Bloomsbury Research Institute
Areas of scientific expertise which are relevant to this call:
The use of microbial genomics to identify reservoirs and transmission of antimicrobial resistance
27
Shona Hilton
MRC/CSO Social and Public Health Sciences Unit, University of
Glasgow
Job title:
Deputy Director and Co-Programme Lead: Informing Healthy Public Policy
Areas of scientific expertise which are relevant to this call:
Since 2005 I have developed a programme of research which aims to understand how health issues and policies are
represented, experienced and understood by people (including the public, health professionals and policy makers); how
people experience the translation of scientific knowledge; and how research evidence is used to promote public health.
As leader of the “Understandings and Uses of Public Health Research” programme and subsequently co-leader of the
“Informing Healthy Public Policy” programme at the MRC/CSO Social and Public Health Sciences Unit, University of
Glasgow I have led a number of projects on high profile public health concerns, including MMR, HPV vaccination and
swine flu. Using content analysis to explore media representations and robust qualitative methods to explore people’s
understandings and experiences of these issues we have produced a volume of peer-reviewed papers published in high
impact journals on each of these topics. This work has also been impactful with policy-makers, we have made a number
of presentations to colleagues in the Department of Health and NHS Health Scotland to convey key insights around
public understandings to shape information and public engagement strategies.
Interests and potential opportunities to explore:
Understanding transmission and the development of antibiotics to treat resistant bacteria are crucial to reduce and control
AMR, however, as well as focusing on biomedical and epidemiological research it seems crucial that work is done to
understand the context of antimicrobial resistance and the impact of social, cultural, and political factors. Like MMR,
HPV and swine flu, antimicrobial resistance (AMR) poses a serious threat to public health and minimising this threat
depends on timely dialogue with the public and the development of communication strategies which are targeted and
sensitive to public understandings, the realities of health professionals prescribing practices, and cultural norms around
antibiotic use. Greater understanding of these issues through media (including social media) analyses and qualitative
research with both health professionals and public groups is likely to be crucial to the development of effective AMR
strategies.
28
Prof Stefan Elbe
University of Sussex
Job title:
Professor of International Relations
Director - Centre for Global Health Policy
Chair - Global Health Section of the International Studies
Association (ISA)
Co-Convener - Global Health Working Group of the British
International Studies Association (BISA)
Areas of scientific expertise which are relevant to this call:
My interests are predominantly in the social science domains of AMR, especially in the area of global health security and
the international politics of health. I am therefore particularly interested in the international diplomacy and global
governance of AMR, the links between AMR and security, and the role of public-private partnerships in developing new
medicines. The expertise includes:



How is the problem of AMR linked to (differing concepts of) security?
How coordinated international diplomatic collective action can be best achieved to tackle AMR?
How public-private partnerships in the area of global health security be used to develop new anti-microbial
medicines?
I have published widely on the international politics of health and global health security, including Security and Global
Health: Towards the Medicalization of Insecurity (Polity Press), Virus Alert: Security, Governmentality and the AIDS
Pandemic (Columbia University Press – recipient of a 2010 Choice Outstanding Academic Title Award), and Strategic
Implications of HIV/AIDS (Oxford University Press). His articles have appeared in leading international relations and
global health journals, including International Studies Quarterly, International Security, The Review of International
Studies, Security Dialogue, Social Science & Medicine, The Lancet, and Health Policy & Planning.
Interests and potential opportunities to explore:

I have a strong interest in the social science aspects of AMR and – as part of this interest – have been involved in
several high-level AMR events held at Chatham House, the ESRC, and Wilton Park.
 Over the past year the Centre for Global Health Policy has also co-convened the Sussex AMR Group, which brings
together social and natural scientists with an interest in AMR across Sussex http://www.sussexamrgroup.org.
 My interest in the workshop is to build contacts and networks in China to see how China and the United Kingdom
could work more closely together to tackle AMR internationally
 I would also be interested in contributing AMR expertise that is reflected in the Centre for Global Health Policy,
such as:
‘Strategies for Achieving Global Collective Action on Antimicrobial Resistance’ by Steven J. Hoffman, Benn
McGrady, Grazia M. Caleo, Nils Daulaire, Stefan Elbe, Danilo Lo Fo Wong, Precious Matsoso, Elias Mossialos,
Zain Rizvi and John-Arne Røttingen. Bulletin of the World Health Organization (in press).
Tackling Antibiotic Resistance for Greater Global Health Security by Gemma L. Buckland Merrett (Cahtham House:
2013)
29
Prof Steve Hinchliffe
University of Exeter
Job title:
Professor of Geography
Contact: Stephen.hinchliffe@exeter.ac.uk
Areas of scientific expertise which are relevant to this call:


Cultural and Social geography, Sociology of Scientific Knowledge
Areas 3 and 4 of the call
Interests and potential opportunities to explore:
I am a social scientist with research expertise in the social dimensions of zoonotic and food borne diseases, as well as
science and technology studies, sociology of scientific knowledge and public engagement. I have recently been funded
by DEFRA to pilot work on the social practices of antibiotic prescription and use on farms. The approach used
ethnographic interviews, Q-methodology and rapid evidence review to build a preliminary understanding of the ways in
which the food and farming sector responds to AMR.
Earlier collaborative work in the food and farming sector has traced the pressures that generate greater pathogenicity
along the food / value chain. I sit on the UK’s Food Standards Agency’s Social Science Research Committee.
More generally, I am a broad based social scientist with expertise in the social ecology of human practices, in social and
actor networks and in the politics of knowledge and public engagement.
30
Thamarai Schneiders
University of Edinburgh
Job title:
Senior Lecturer
Contact: Thamarai.Schneiders@ed.ac.uk
Areas of scientific expertise which are relevant to this call:
The expertise within the University of Edinburgh, collectively known as Edinburgh Infectious Diseases, consists of
research into the basic, clinical, veterinary and socioeconomic aspects of antimicrobial resistance. The basic and clinical
research focus of AMR research is hosted within the Division of Infection and Pathway Medicine (DIPM), which
represents a collaboration between NHS staff and academia in researching both the mechanistic details of antibiotic
resistance development but also tackles broad-ranging clinical issues around antimicrobial stewardship. Research into the
fundamental basis of resistance development is also undertaken within the School of Biological Sciences in collaboration
with the School of Physics.
The investigations into basic mechanisms support the development of targets for translation into patient care specifically
in the development of point of care diagnostic devices. The Innogen Institute works on innovation pathways for the
development of new antimicrobials, interactions between regulation and innovation, prescription patterns and other
societal issues relevant to the development of AMR and solutions to the problem.
Interests and potential opportunities to explore:
The interests in attending this workshop would be to represent the broad-ranging expertise within the University of
Edinburgh to potential collaborators. Given the collective range expertise within UoE seeks to explore potential
opportunities in the following areas:
Module 1: Basic Mechanisms of Resistance –This will include a systematic analyses of defining microbial AMR
development using both molecular and bio-physical methods. The studies into both clinical/veterinary and environmental
samples will evaluate for emerging mechanisms of resistance in novel epidemic clones. Critically, we will build on
Edinburgh’s success in sequencing to track the transmission dynamics between the human/veterinary/environmental
spheres.
Module 2: Antimicrobial Stewardship-To gain a broader understanding off actors that facilitate differing prescribing
practices to develop targeted interventions and policies. We will also seek to develop an understanding of antibiotic
consumption data and AMR surveillance to garner a greater understanding of antimicrobial usage patterns.
Module 3: Mapping the supply chain for antibiotics for people and animals including factors influencing the
development of novel AM drugs and the use of existing drugs.
31
Timothy Walsh
Cardiff University
Job title:
Head of Microbiology Research
Areas of scientific expertise which are relevant to this call:
AMR mechanisms, AMR epidemiology in clinical and veterinary sectors, assessing the burden of AMR, Application of
mathematical models to better understand AMR, Evaluation of novel antibiotics.
Interests and potential opportunities to explore:
Joint UK/Chinese funding opportunities
32
Prof Xiaodong Zhang
Imperial College London
Job title:
Professor of Macromolecular Structure and Function
Director - Centre for Structural Biology (2011-2014)
Areas of scientific expertise which are relevant to this call:
I studied Physics in China (BSc) and USA (PhD) before becoming a structural biologist. My research focuses on
understanding molecular mechanisms of large macromolecular machines, with a particular interest in DNA processing
enzymes including those involved in gene transcription in bacteria using cryo-electron microscopy and X-ray
crystallography. Many transcription factors and the transcription core enzyme, the RNA polymerase, are proven
antibiotic targets and understanding their structures and mechanisms are key to new antibiotic development. More
importantly, we need to focus on developing new antibiotics or combining existing antibiotics that intrinsically prevent
bacteria from developing resistance. Such an informed design and development can only come from fundamental
understanding of the molecular mechanisms behind the drug targets as well as the mechanism of resistance. Our work on
transcription factors that control the over-expression of efflux pumps, responsible for excluding antibiotics, provided
structural basis of how these transcriptional factors recognise antibiotics as well as how they are activated (Alguel et al.,
JMB 2007, Alguel et al. JSB 2010, Lu et al. Genes and Dev, 2010). Our work on the major variant sigma factor, sigma54,
responsible for stress related genes including virulence factors, with our landmark work on the structures and
mechanisms (Rappas et al., Science 2005, Bose et al. Mol Cell, 2008, Yang et al. Science 2015) reveal how RNA
polymerase is inhibited by sigma54 and how they are activated. We discover a number of hotspots within RNA
polymerase that has yet to be targeted. Furthermore, since sigma54 does not regulate essential house keeping genes, the
pressure to develop resistant against drugs targeting sigma54 might be reduced.
Interests and potential opportunities to explore:
Given my interest in the molecular mechanisms of molecules, especially those contribute to antibiotic development and
resistance, I would be interested in attending this workshop to share knowledge with others, especially those from
different aspects and with different expertise. I would especially like to explore ways to combine a number of targets that
would then form a self-regulated system to reduce the probability and thus rate of resistance development.
33
UK-China AMR Workshop
Chinese Researchers’ Biographies
23 – 27th November 2015
34
Prof ADong Shen
Beijing Pediatric Research Institute，Beijing Children's Hospital, Capital Medical University
Job title:
Professor of Capital Medical University
Contact: shenad16@hotmail.com or 13370115087@163.com
Areas of scientific expertise which are relevant to this call:
Infection control programmes within paediatric setting.
Interests and potential opportunities to explore:
Antimicrobial Resistance within paediatric CAP or TB.
35
Prof Baoli Zhu
University of Chinese Academy of Sciences (UCAS), CAS Laboratory of Pathogenic Microbiology and
Immunology, Chinese Academy of Sciences (CAS), Institute of Microbiology
Job title:
Professor of University of Chinese Academy of Sciences (UCAS);
Principal Investigator - CAS Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology,
Chinese Academy of Sciences (CAS);
Director - Microbial Genome Research Center, Institute of Microbiology
Contact: zhubaoli@im.ac.cn
Areas of scientific expertise which are relevant to this call:
Areas of scientific expertise: comparative genomics on MDR and XDR of clinical isolates of Mycobacterium
tuberculosis; Pathogenomics on pan-drug resistance bacterial strains isolated from hospital-acquired infections
(nosocomial infection); Metagenomic analysis of antibiotic resistance genes in human gut microbiota, animal gut
microbiota and environmental metagenomes.
Interests and potential opportunities to explore:
Epigenomics on TB genomes that may be involved in pathogeneicity and drug resistance; large-scale analysis on MDR
and XDR strains to study the evolution of drug resistance in Mycobacterium tuberculosis; Drug resistance gene flow
from the food chain to the hospitals.
36
Cai-Guang Yang
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Job title:
PI of Shanghai Institute of Materia Medica
Contact: yangcg@simm.ac.cn
Areas of scientific expertise which are relevant to this call:
Development of antiinfective therapy by targeting virulence:
The extensive use of antibiotics to treat infections has led to the emergence of high-level resistances in various strains of
pathogenic bacteria. The global spread of antibiotic resistance emphasizes the need to find new antibiotics, particularly
those with novel modes of action. We sought to alternative strategies for combating bacterial infection: target-gain-offunction instead of loss-of-function and reducing bacterial virulence instead of killing bacteria.
Interests and potential opportunities to explore:
Our research program spans a broad range of chemical biology, structural biology, microbiology, and molecular
pharmacology, particularly focuses on target validation and chemical probes development for antibacterial drug
discovery. We probe the mechanism and pathway of virulence regulation of pathogenic bacteria. We also develop smallmolecule modulators to control bacterial infection.
37
Debin Wang
School of Health Services Management, Anhui Medical University
Job title:
Deputy Dean - School of Health Services Management, Anhui Medical University
Contact: dbwang@vip.sina.com
Main research experience:
1. 2015-2016: Got funded, as the principle investigator, by UK-China Prosperity Fund and initiated, in collaboration
between Anhui Medical University of China and the Public Health England, a project aimed at developing and evaluating
a low cost, effective and sustainable intervention package tackling antimicrobial resistance in rural Anhui, China.
2. 2012-2015: Got funded, as the principal investigator, by the China Natural Science Foundation, and developed and
validated a web-based practical package of cancer-related behavior intervention.
3. 2006-2008: Got funded, as a principal investigator, by the then Foreign Loan Office of China Ministry of Health, and
implemented an end-point evaluation of H9 HIV/AIDS/STD Intervention, a multi-province comprehensive intervention
project against HIV/AIDS/STDs co-funded by the Government of China and the World Bank/IDA.
4. 2005-2006: Got funded, as a co-principal investigator, by the National Institute of Mental Health of the United States
of America, and implemented, in collaboration with researchers at US UCLA and UCSF, and UK Oxford, a project
aimedat integrating HIV/STI prevention and treatment at clinical settings.
5. 2004-2006: Got funded, as the principal investigator, by the China Natural Science Foundation, and implemented a
projectaimed at developing practical packages of HIV/STI-related behavior interventions at clinical settings.
6. 2003-2005: Got funded, as a principal investigator, the World AIDS Foundation and implemented, in collaboration
with researchers from Anhui Medical University China and UCSF and UCLA of America, a project aimed at training
physicians working with HIV positives and preventing secondary transmission.
7. 2001-2003: Got funded, as a co-principal investigator, by the World AIDS Foundation and implemented a project
aimed at empowering community level health workers to combat STD/AIDS using contemporary knowledge and
creative problem solving.
Areas of scientific expertise which are relevant to this call:
Over 20 year of research experience on health behaviour intervention and health services research with particular interest
in: a) understanding residents’ knowledge/attitudes/ expectations about antimicrobials and physicians’ prescribing
behaviors; and b) using effective methods addressing overuse/misuse of antimicrobials.
Interests and potential opportunities to explore:
Understanding behaviors in order to reduce the development, emergence and spread of antimicrobial resistance within
and beyond human and animal healthcare settings including antibiotic prescribing and also broader public health
approaches such as in hygiene and infection control practices in both human and animal settings and factoring in barriers
to behavior change such as organizational and cultural norms, and financial incentives to prescribe drugs.
38
Prof En-Min Zhou
Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University
Job title:
Dean - College of Veterinary Medicine
Distinguished Professor of Northwest A&F University
Contact: zhouem@nwsuaf.edu.cn
Education:
Ph.D. (1993, Immunology), Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg,
Canada
M.D. (1982, Medicine), Baotou Medical College, Baotou, China
7/2007 – 6/2010, “Taishan Scholar” and Distinguished Professor, Associate Dean, College of Veterinary Medicine,
Shandong, Agricultural University, TaiAn, China
Professional experience:
5/2006 – 7/2007, “Longjiang Scholar” and Distinguished Professor, Department of Preventive Veterinary Medicine,
College of Animal Science and Technology, BaYi Agricultural University, Daqing, China
6/2000 – 5/2006, Head, Serology Section, Veterinary Diagnostic Laboratory, Department of Veterinary Diagnostic and
Production Animal, Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
12/2002- 12/2005, Adjunct Professor, Department of Veterinary Microbiology, College of Veterinary Medicine,
Northeast Agriculture University, Harbin, China
9/1998-6/2000, Adjunct Associate Professor, Department of Animal Science, University of Manitoba, Winnipeg,
Manitoba, Canada
4/1996-5/2000, Senior Research Scientist and Head of Immunodiagnostic Laboratory, National Centre for Foreign
Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada
7/1992- 3/1996, Research Scientist, Virology Section, Animal Diseases Research Institute, Agriculture Canada, Nepean,
Ontario, Canada
1/1995-12/1998, Adjunct Assistant Professor, Department of Microbiology and Immunology, University of Ottawa,
Ottawa, Canada
9/1985-8/1988, Visiting Scientist and Postdoctoral Fellow, Department of Virology and Immunology, Southwest
Foundation for Biomedical Research, San Antonio, Texas, USA
Areas of scientific expertise which are relevant to this call:
PRRSV and host interaction and PRRSV immune regulation;
Avian hepatitis E virus zoonosis and epitope mapping.
39
Fuping Hu
Institute of Antibiotics, Huashan Hospital, Fudan University
Job title:
Director of Clinical Microbiology
Contact: hufupin@163.com
Areas of scientific expertise which are relevant to this call:
1. Study on bacterial resistance monitoring research;
2. Mechanisms of antibacterial resistance, especially for b-lactamases and 16S rRNA methylases;
3. Epidemiology of carbapenem-resistant Enterobacteriaceae and Acinetobacter spp.
Interests and potential opportunities to explore:
Because carbapenemase-producing Enterobacteriaceae isolates are usually extensively drug resistant, infections caused
by carbapenem-resistant Enterobacteriaceae (CRE) present a serious clinical challenge for physicians in healthcare
settings. Treatment options for these infections are limited and few clinical data are available on which to base antibiotic
recommendations. Moreover, the use of inappropriate empirical antibiotic therapy or delayed appropriate antibiotic
therapy can lead to worse outcomes. Previous studies have found crude mortality rates ranging from 30% to 44% for
diverse infections caused by CRE. The prevalence of CRE clinical isolates has increased significantly in Shanghai since
2005. I would be interested to study reducing the development, emergence and spread of antibacterial resistance (within
and beyond human and animal healthcare settings).
40
Prof George Fu Gao
Institute of Microbiology, Chinese Academy of Sciences
Job title:
Professor of CAS Key Laboratory of Pathogenic Microbiology and Immunology
Director - CAS Key Laboratory of Pathogenic Microbiology and Immunology
Vice-President - Beijing Institutes of Life Science, Chinese Academy of Sciences
Deputy Director - General of Chinese Centre for Disease Control and Prevention (CCDC)
Contact: gaof@im.ac.cn
He obtained his Ph.D (DPhil) degree in 1995 from Oxford University, UK. He was selected in the Chinese Academy of
Sciences "Hundred Talents" program in 2004, and got National Natural Science Foundation of China (NSFC)
Distinguished Young Scholar title in 2005. He is the chief scientist of two consecutive 973 project “mechanism of
interspecies transmission of viral pathogens” (2005, 2011), and a leading principal investigator of the NSFC Innovative
Research Group. He is also a steering committee member of International Consortium of Anti-Virals (ICAV), and
visiting professor in Oxford University, UK. He has been awarded TWAS prizes in Medical Sciences in 2012 and been
awarded Nikkei Asia Prize in 2014.
Education and Appointment:
1979-1983, Shanxi Agricultural University, China B.Sc, DVM;
1983-1986, Beijing Agricultural University, China M.Sc;
1991-1994, Oxford University, United Kingdom, DPhil;
1987-1991, Teaching Assistant and Lecturer (Virology), College of Vet. Med., Beijing Agricultural University (BAU),
P.R. China;
1995-1998, Wellcome Trust/MRC Postdoctoral Research Assistant (RS1A), Nuffield Dept. of Clinical Medicine,
Institute of Molecular Medicine, Oxford University, Drs John Bell, Andrew McMichael and Bent Jakobsen lab. (Three
months of Academic visit as a postdoc fellow at Dept. of Clinical Neurosciences, Dr Robert Bell lab, The University of
Calgary, Canada, in the end of 1994, before taking up the Oxford postdoc position);
1998-1999, Research Associate (Band 3), MRC Human Immunology Unit, Institute of Molecular Medicine, University
of Oxford;
1999-2001, Wellcome Trust (UK) International Research Fellow, Howard Hughes Medical Institute, Children's Hospital;
Dept. of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; and Dept. of Molecular and
Cellular Biology, Harvard University (Drs Don C Wiley and Stephen C Harrison lab);
2001-2006, Research Lecturer, Nuffield Dept. of Clinical Medicine, Oxford University;
2004-2008, Professor, Director-General, Institute of Microbiology, Chinese Academy of Sciences (IMCAS).
Areas of scientific expertise which are relevant to this call:
His research is focusing on mechanisms of interspecies transmission (“host jump”) of pathogens, especially interaction
between the enveloped viruses and host, and molecular immune recognition, and public health policy and health policy
research around the world. He has published more than 330 refereed papers.
41
Haihui Huang
Institute of Antibiotics, Huashan Hospital, Fudan University
Job title:
Deputy Director - Institute of Antibiotics
Contact: huanghaihui@fudan.edu.cn
Areas of scientific expertise which are relevant to this call:
Molecular epidemiology of Clostridium difficile infection; resistance and resistance mechanisms of Clostridium difficile,
Bacaeroides fragilis and Propionibacterium acnes; Clinical trials on new antibiotics on anaerobes.
Interests and potential opportunities to explore:
Resistance mechanisms of Clostridium difficile and Bacaeroides fragilis: novel molecular mechanisms underlying
antibiotics resistance.
42
Prof Hanchun Yang
College of Veterinary Medicine, China Agricultural University
Job title:
Professor of China Agricultural University
Associate Dean - Scientific research and international affairs at College of Veterinary Medicine, China Agricultural
University
General Secretary - Chinese Association of Animal Science and Veterinary Medicine (CAAV)
Director - Key Laboratory of Animal Epidemiology and Zoonosis of the Chinese Ministry of Agriculture (MOA)
Contact: yanghanchun1@cau.edu.cn
Areas of scientific expertise which are relevant to this call:
He focuses on the area of swine viral diseases, especially on porcine reproductive and respiratory syndrome (PRRS),
porcine circovirus type 2 (PCV2) infection, encephalomyocarditis virus (EMCV) and porcine epidemic diarrhea virus
(PEDV) etc.
Interests and potential opportunities to explore:
His major interests include molecular epidemiology, virus-host interaction, infection and pathogenesis, and immunology
and novel vaccines of these viruses.
43
Prof Hui Wang
Department of Clinical Laboratory, Peking University People’s Hospital
Job title:
Professor of Department of Clinical Laboratory
Director - Department of Clinical Laboratory
Contact: wanghui@pkuph.edu.cn or whuibj@163.com
Hui Wang, Professor and Director of Department of Clinical Laboratory, Peking University People’s Hospital. Professor
Wang graduated from Peking Union Medical College (PUMC) with Master degree in 1999 and acquired M.D degree in
2006. She worked in Department of Clinical Laboratory, Peking Union Medical College Hospital (PUMCH) from 1994
to 2010; then moved to Peking University People’s Hospital and took the position of director of department of clinical
laboratory till now.
Her research interests focus primarily on antimicrobial resistance and resistance mechanism. Professor Wang has been
invited by international academic conferences as invited speaker for more than 10 times in the recent 5 years, gaining
high reputation in this field. In addition, she published an invited review in the highly prestigious journal of Lancet
Infectious Diseases. Sponsored by grants from National Natural Science Foundation and Program for New Century
Excellent Talents in University, she has published 61 papers in peer-review SCI cited journals (36 papers as the
corresponding author), with a total impact factor of 236, other citation times 1093. Meantime, she has published 211
papers in Chinese journals, with other citation times 6923. She also had three papers cited by F1000 Prime. Another 2
articles were selected as “Top 100 academic papers in China”. She had the honor of National Scientific and
Technological Progress Second Prize.
Due to her exceptional academic achievements, Professor Wang Hui was appointed advisor of the Antimicrobial
Susceptibility Testing Subcommittee of Clinical and Laboratory Standards Institute (CLSI). She is also the Executive
Committee member of Asian Network for Surveillance of Resistance Pathogens (ANSORP) and APEC Health Working
Group. In addition, she is the head of branch of clinical microbiology, Chinese Society of microbiology and immunology,
Chinese Medical Association, and Standing Council member of Global Chinese Association of Clinical Microbiology
and Infectious Diseases.
Education:
2003-2006: Studied at Peking Union Medical College, MD Degree;
1999-2000: Studied at Tufts University as visiting scholar;
1996-1999: Studied at Peking Union Medical College, Master Degree;
1989-1994: Studied at West China Medical Center Sichuan University, Bachelor Degree.
Areas of scientific expertise which are relevant to this call:
Antimicrobial resistance and resistance mechanism
Interests and potential opportunities to explore:
1.
2.
Antimicrobial resistance and resistance mechanism;
Studies on carriage of resistant bacteria in the general population.
44
Prof Huiqing Yuan
Department of Biochemistry and Molecular Biology, Shandong University School of Medicine
Job title:
Professor of Department of Biochemistry and Molecular Biology
Director - Department of Biochemistry and Molecular Biology
Contact: lyuanhq@sdu.edu.cn
Interests and potential opportunities to explore:
1. Screening for identification of novel antitumor agents with anti-microbiological activity from naturally occurring
chemicals;
2. Analysis of gene functions in cancer associated with multidrug resistance via genetic and epigenetic modification
mechanisms;
3. Oncogenic protein expression determines a differential response to antitumor drugs: potential applications in
personalized chemotherapy.
45
Jianping Xie
Institute of Modern Biopharmaceuticals, School of Life Sciences, Southwest University
Job title:
Deputy Director - Institute of Modern Biopharmaceuticals
Contact: georgex@swu.edu.cn
Areas of scientific expertise which are relevant to this call:
Mycobacterium tuberculosis antibiotics resistance. Microbial genetics, functional genomics of drug resistant microbes,
host immunity against drug resistant pathogens, novel phage based platforms for improved antimicrobial agents,
integrated control measures against drug resistant pathogens from food chain to clinic, the flow of drug resistant genes
among microbiome, microbial ecology of drug resistant pathogens.
Interests and potential opportunities to explore:
1. Novel molecular mechanisms underlying antibiotics resistance and countermeasures thereof, such as toxin-antitoxin,
persisters, metabolism regulator; 2. Phages inspired novel measures against antibiotics resistant pathogens; 3. Biofilm
related antibiotics resistance and countermeasure; 4. Role of post-translational modifications in the antibiotics resistance.
46
Prof Juan Li
Department of Antibiotics Resistance, National Institute for Communicable Disease
Control and Prevention, China CDC
Job title:
Associated professor of Department of Antibiotics Resistance
Deputy Director - Department of Antibiotics Resistance
Contact: lijuan@icdc.cn
Juan Li was born in Shandong Province, People’ Republic of China. After getting her bachelor’s degree of medical
science from WeiFang medical University in 2001, she entered to Academy of Military Medical Sciences, where she
received her Master’s degree in Mycobacterium tuberculosis research. In 2004, she transferred to Institute of
Microbiology Chinese Academy of Sciences, worked on research of medical fungi, during three years study, she
identified a novel candida species isolated from a cancer patient, utilized a new method for rapid strain typing of Candida
albicans and discovered biased genotype distribution of Candida albicans strains associated with vulvovaginal
candidosis and candidal balanoposthitis in China. Since receiving her doctor’s degree in 2007, she has been working in
National institute for Communicable Disease Control and Prevention, China CDC, focusing on genetics, biochemistry
and epidemiology of antibiotic resistance determinants, especially metallo-ß-lactamases and other carbapenem resistance
determinants. From 2012 to 2015, she is directing the research project “Genetic and biochemical characterization of
ISCR1 complex integron antibiotic resistance gene cassettes”. Recently, she is involving in the national major project
“epidemiology, prevention and control of super-resistance bacteria”. So far she has co-authored in more than 30 articles
in academic journals.
47
Prof Ling Lu
Nanjing Normal University
Job title:
Professor of Nanjing Normal University
Contact: linglu@njnu.edu.cn or linglu6465@hotmail.com
Areas of scientific expertise which are relevant to this call:
1. Molecular and biochemistry techniques for pathogenic filamentous fungi;
2. Screening and identification for clinic azole-resistance isolates of Aspergillus fumigatus;
3. Validation of novel mutated genes conferring azole resistance in A. fumigatus;
4. Establishment for the immunocompromised mice model of invasive pulmonary aspergillosis.
Interests and potential opportunities to explore:
Based on molecular and biochemistry techniques including live-cell imaging, library screening, and
immunocompromised mice model of invasive pulmonary aspergillosis, mammalian cell line model etc., our research
group have systematically verified that the molecular mechanism of the azole drug response by using filamentous fungus
Aspergillus nidulans and Aspergillus fumigatus as the research materials. Our findings want to gain an insight in the new
solution for fighting for drug resistance and for the treatment of aspergillosis.
48
Prof Minggui Wang
Institute of Antibiotics, Huashan Hospital, Fudan University
Job title:
Professor of Fudan University
Chief-in-Physician of Huashan Hospital
Director - Institute of Antibiotics, Huashan Hospital
Vice Director - Division of Infectious Diseases, Huashan Hospital
President - Committee of Society on Infectious Diseases and Chemotherapy, Shanghai
Medical Association
Section Editor - International Journal of Antimicrobial Agents and Journal of Global
Antimicrobial Resistance
Contact: mgwang@fudan.edu.cn
Areas of scientific expertise which are relevant to this call:
His research interests are bacterial resistance and mechanisms of bacterial resistance; clinical studies of new
antimicrobials. He focuses on plasmid-mediated resistance in gram-negative bacilli including resistance to quinolones,
beta-lactams (cephalosporins and carbapenems), tigecycline, aminoglycosides, and fosfomycin. His research group has
reported two new bacterial resistance genes, quinolone-resistance gene qnrC (AAC 2009) and vancomycin-resistance
gene vanM (AAC 2010), and several new resistance gene subtypes such as fosfomycin-resistance gene fosA5 (LAM
2015).
Interests and potential opportunities to explore:
1.
Novel resistance mechanisms of tigecycline in Klebsiella pneumonia;
2.
Novel molecular mechanism of drug resistance in carbapenem-resistant Enterobacteriaceae;
3.
Novel resistance and regulation mechanisms in quinolone-resistant Enterobacteriaceae;
4.
Whole genome sequencing (WGS) and comparative genomics based mining for drug resistance determinants and
virulent factors in clinical Enterobacteriaceae isolates.
49
Prof Qunhong Wu
Harbin Medical University
Job title:
Professor of Harbin Medical University
Adjunct professor of La Trobe University, Melbourne, Australia
Leading professor of Key Discipline of Heilongjiang in health service management
Chief Scientist of the First class research Team in Health Management of Heilongjiang Province
Executive Dean - Health Management College
Director- Health Policy and Management Research Center
Contact: wuqunhong@163.com
Research activities involved:
1. 2013-2018 PI, Study on Theory of Universal Coverage of Medical Insurance, evaluation on its effectiveness and
optimized approaches for future reform and system Integrating, 2.25 million RMB, granted by National Scientific Fund
of China;
2. 2014-2015, PI, Study on conflicts between Doctor-Patient, influencing factors and coping strategies. 200,000 RMB,
granted by Ministry of Health;
3. 2013-2015, PI, Study on the impact of health reform on the development of rural health Workforce, 200,000 RMB,
granted by Ministry of Health;
4. 2010-2013, PI, Study on key strategies and techniques for strengthening public health emergency response capacity
and design on online training and capacity building program for China, 18.6 million RMB, jointly granted by Ministry of
Health and Ministry of Science and Technology in China;
5. 2010-2013 PI, Study on causes and mechanism of hospital regulation failure &countermeasures for addressing it,
RMB 290,000, granted by National Scientific Fund of China;
6. 2009.1-2014.1, PI, Evaluative study on pilot public hospital reform $300,000 (USD), granted by CMB;
4. 2009.1-2012.12 PI, Comparative study of healthy people plans of different countries & establishing evaluating
indicators of health 2020 in China, $150,000 USD, granted by CMB;
5. 2010.5-2011.5, PI, Situational study on the quality and quality performance management in rural hospital of China,
RMB 100,000, granted by World Bank XI health project;
6. 2009.5-2010.5 PI, Evaluation Study on effectiveness of essential drug reform in pilot counties in Heilongjiang
province, RMB, 100,000, World bank XI health project;
7.2008.1-2009.12 PI, Study on methodology of evaluating the cost-effectiveness of HBV drug treatment, granted by
National Research Institute of Strategy of Science and Technology Development 100,000 RMB;
8.2006.12-2008.12 PI, Research on the Evaluation of Emergency Response Capacity of Health System and its
Management information System, RMB1.94 million, granted by the National 863 Project from the Ministry of Science
and Technology;
9.2006.12-2009.12 Co-PI, Study on Exploring Evaluating Indicator sets of measuring performance of CDC, RMB240,
000 Granted by the National Scientific Fund of China;
10.2005.12-2008.12 PI, Research on Setting up Evaluation Indicator System for Measuring Emergency Response
Capacity of Health System of China, 300, 000RMB, Granted by The National Scientific Fund of China.
50
Prof Shijun Ding
Agricultural economics and rural development, Zhongnan University of Economics and Law
Job title:
Professor in agricultural economics and rural development
Contact: dingshijun2006@aliyun.com
Areas of scientific expertise which are relevant to this call:
Areas: Livestock production and animal disease.
I have been involving in several relevant research projects:
1) Protecting animal and human health in rural China: a scoping study in Hubei and Yunnan Provinces: The aim of this
study is to increase understanding on the links between animal health and human health in rural China by pulling
together the available data, to map out the roles of the different agencies responsible for both animal and human health,
and to document the different perceptions of stakeholders on the risks of animal and human disease and their strategies in
response.
2) Responding to zoonotic and related diseases in intensifying livestock systems: diverse framings and pathways: The
project gathers information on zoonotic diseases and other sources of ill-health from people involved in different forms
of pig production. It seeks to catalyze reflection among the different actors, who shape pig production systems in China,
on the implications of the diverse health burdens for the choice and shape of policies and practices.
3) Rethinking of technology regulations: the case of transgenic cotton seeds and antibiotic medicines: The project
compares the regulation of two technologies - transgenic cotton seeds and antibiotics - with the way those technologies
are experienced amongst poorer communities in rural China. It explores the implementation challenges facing regulators;
and understands the kinds of inclusive regulatory designs that can incorporate issues relevant to poorer communities.
Interests and potential opportunities to explore:
Topic: Antimicrobial use, resistance and the socioeconomic factors in pig production in China
Objectives:
1) Investigate patterns of antimicrobial use in pig production; 2) Explore knowledge/perceptions of different stakeholders
on use of antimicrobial and its resistance; 3) Understand behaviours/strategies of stakeholders for ensuring access to
antimicrobial; 4) Provide micro-level scientific evidence for policymakers in regulating use of antimicrobial.
Abuse of antimicrobial in livestock production in China is serious. A recent investigation shows that 52% antimicrobial
residue in China’s major rivers come from livestock production. Media also reported that children have been found
holding resistant bacteria from livestock production. But few research pay attention to animal producer’s and other
stakeholders’ knowledge and perception/behavior on antimicrobial. On the other hand, livestock such as pig production
is going through intensification, backyard producers are exiting and intensified producers are become major pork market
suppliers. This kind of change makes antimicrobial use much more complex in that producers may use much more
antimicrobial in animal disease treatment and growth promoting. Given these background, investigate different
actors/stakeholders’ (i.e. producers, vets, doctors, medicine and feed dealers, meat consumers, slaughter houses and so on)
antimicrobial using knowledge, behaviour, antimicrobial resistance perception and the socioeconomic factors is
important.
51
Prof Xiaofang Wang
Department of Management Science and Engineering, School of Business, Renmin University of China
Job title:
Associate Professor of Department of Management Science and Engineering, School of Business
Contact: wangxiaofang@rbs.org.cn
Areas of scientific expertise which are relevant to this call:
Relevant research grants:
1. “Design and Optimization of Healthcare Triage Systems,” supported by Outstanding Youth Foundation, National
Natural Science Foundation of China;
2. “Service Operations Management with Healthcare Applications,” supported by the Program for New Century
Excellent Talents in University, Ministry of Education in China.
Interests and potential opportunities to explore:
1. Physicians’ prescribing behavior in antibiotics;
2. Relevant policies in containing costs and maintaining quality of care;
3. Role of community hospitals in reducing unnecessary care and alleviating congestion at major public hospitals in
China;
4. The impact of reimbursement policies and service pricing.
52
Prof Xinglin Feng
School of Public Health, Peking University Health Science Centre
Job title:
Associate professor in health policy
Contact: fxl@bjmu.edu.cn
Areas of scientific expertise which are relevant to this call:
Frankly, I have no experiences relevant to the research on antimicrobial resistance. My specific study areas are: 1) Health
policy and system research; 2) Health economics evaluation 3) Primary health care and 4) Health service research
(analysing surveys).
Interests and potential opportunities to explore:
I have been involved in the following research projects.
(1) January, 2015- , Principal investigator: Health system strengthening and universal health coverage. Supported by
China National Natural Science Foundation for Outstanding Youth Fund (71422009); (2) January, 2014- ; Principal
investigator: Research on the finance of birth defects control in China. Supported by National Natural Science
Foundation of China (71303010) (3) January, 2013- , Principal investigator: Vertical integration and the performance of
community health care in China. Supported by the Program for New Century Excellent Talents in University, NCET-120009; (4) January, 2013- , Principal investigator: Demand side subsidies and medical impoverishment for delivery carerole of provider payment arrangement. Supported by China Medical Board; (5) September, 2013- , Principal investigator:
Analysis on the 5th National Health Service Survey in Jilin Province, China. Supported by the Information and Statistics
Centre of Jilin Province, China; (6) 2014.3 - , Co-investigator: China-UK Global Health Support Programme-Research
on Health Systems Strengthening in Global Health in China, supported by the department for international development
(DFID).Responsibility: China’s rural health service delivery system- experience and lessons for African countries; (7)
2014.1- , Co-investigator: Economic evaluation of the prenatal screening and prenatal diagnosis system in Beijing and
investigation on the strategies to optimize resource allocation. Supported by Beijing Science and Technology Committee
CBKT20134282. Responsibility: health economics evaluation and human resource planning; (8) May, 2011-May, 2012,
Principal investigator: Reclassify the socio-economic county level regions in China using Bayesian statistical methods; (9)
May, 2010-May, 2011, Principal investigator: Policy analysis and recommendation for public hospital reform in China.
Supported by the Chinese Pharmaceutical Association; (10) January, 2010- January, 2012, Principal investigator: Social
determinants on the inequality of child health in China. Ministry of Education social science grants 09YJCZH004; (11)
November, 2008- November, 2009, Principal investigator: Social determinants on the horizontal inequality of maternal
health care utilization in China supported by China Medical Board; (12) July, 2009- July,2011, Co-investigator: Research
on Social Determinates of Health for Safe Motherhood in China supported by China Medical Board. Responsibility:
proposal drafting, grant applying, data collecting, analysing and report drafting; (13) October, 2009-October, 2010, Coinvestigator: Research on Social Determinants of maternal and infant mortality in China supported by UNICEF.
Responsibility: proposal drafting, grant applying, data collecting, analysing and report drafting; (14) January, 2008January, 2009, Co-investigator: Research on strategy for the fulfilment of MDGs 4 and 5 in China supported by MOH,
China. Responsibility: data analysing; (15) May, 2007-May, 2009, Co-investigator: Research on Social Determinates of
Maternal Mortality in China supported by WHO. Responsibility: proposal drafting, grant applying, data collecting,
analysing and report drafting. (16) November, 2006-July, 2009, Co-investigator: An Impact Evaluation of the Safe
Motherhood Program in China supported by Global Development Network. Responsibility: proposal drafting, grant
applying, data collecting, analysing and report drafting; (17) May,2005-January, 2006, Co-investigator: Joint Review of
the Maternal and Child Survival Strategy in China Collaborated with MOH China, UNICEF, WHO and UNFPA.
Responsibility: data analysis, report drafting (technical report) and launching; (18)
February-December, 2004, Coinvestigator: China Medical Board International Medical School Faculty Development Needs Assessment Survey
cooperated with Global REACH, University of Michigan Medical School, Responsibility: translating the survey
instrument, colleting, inputting and analysing data.
53
Prof Yang Wang
China Agricultural University
Job title:
Associate Professor of China Agricultural University
Vice Head - Lab for the development, transmission and control of antimicrobial resistance
Contact: wangyang@cau.edu.cn or vetwangyang@163.com
Areas of scientific expertise which are relevant to this call:
1. Antimicrobial resistance in Gram-positive/ Gram-negative bacteria;
2. Structure and regulation of antibiotic resistance genes;
3. Molecular epidemiology of plasmids, transposons, gene cassettes and integrons;
4. Monitoring of antimicrobial susceptibility;
5. Molecular typing of bacteria.
Interests and potential opportunities to explore:
The joint Chinese/UK funding opportunities on important antimicrobial resistance gene in bacteria of animal,
environment and human origin.
54
Prof Yaoyu Feng
School of Resource and Environmental Engineering, East China University of Science and Technology
Job title:
Professor of School of Resource and Environmental Engineering
Contact: yyfeng@ecust.edu.cn
Areas of scientific expertise which are relevant to this call:
I have been working on food and water microbial safety since 2000, focusing on molecular epidemiology and
environmental ecology of foodborne and waterborne parasites. I am also working on the algal bloom, especially to the
relationship among algal bloom outbreak, lake ecosystems, and water quality. Specific research areas include:
1. Genomics, molecular epidemiology and diagnosis, and environmental biology of foodborne and waterborne pathogens
(such as Cryptosporidium, Giardia, microsporidia, and other protozoan parasites of humans and animals);
2. Pathogenesis of waterborne pathogens
3. Structure, function and interaction of microbial community in lake ecosystems in association with algal bloom
formation
4. Rapid detection of environmental pollutants and development of related biosensors and function materials
Interests and potential opportunities to explore:
Antimicrobial resistance of waterborne, foodborne and nosocomial pathogens, the dispersal of antibiotic-resistance genes
in wastewater treatment plants, environmental ecology of antimicrobial resistance, and effect of concentrated animal
feeding operations on antibiotic resistance.
56
Prof Ying Wu
School of Nursing, Clinical Nursing College, Capital Medical University
Job title:
Professor of Capital Medical University
Dean - School of Nursing, Clinical Nursing College, Capital Medical University
Vice President Elect - International Medical Informatics Association
Contact: helenywu@vip.163.com or helenywu@ccmu.edu.cn
Areas of scientific expertise which are relevant to this call:
• Health related behaviors and their underlining mechanism of patient and healthcare professionals;
• Guideline Adherence by health care workers;
• Medication and risk factor modification adherence, interventions to increase adherence using mobile health technology;
Current relevant research grants:
• SMART Integrated Elderly Care Model Based on Human Nervous Response Principle: Underlining Coordinative
Mechanism, Development, and Implementation. National Natural Science Foundation;
• The Development and Evaluation of Health Behavior Change Model and Mobile Health Management Model for
Patients with Coronary Heart Disease. National Natural Science Foundation.
Interests and potential opportunities to explore:
• Routes of MDROs dissemination;
• Mechanism of MDROs dissemination;
• Practice or behavior Model of health-care professional regarding adherence to recommended practice guidelines against
MDROs dissemination;
• Increase health-care professional’s adherence by using advanced hospital information technologies and mobile devices.
57
Prof Yonghong Yang
The Beijing Children’s Hospital, Capital Medical University, Beijing Pediatric Institute
Job title:
Professor of Capital Medical University and Beijing Pediatric Institute
Contact: yyh628628@sina.com
Since 1982, Dr. Yonghong Yang has worked as an attending pediatrician, an associate professor and Professor in the
Beijing Children’s Hospital affiliated to Capital Medical University and Beijing Pediatric Institute. From 1994 to 2005,
he served as deputy director of the hospital and the Institute.
Dr. Yang was trained at the National Institutes of Health (NIH) in the U.S. from 1985 to 1988. Twenty years ago, he
established a Laboratory of Microbiology and Immunology and led a World Health Organization (WHO) project on
etiologic and epidemiologic studies of bacterial meningitis in China. In 1999, he became the Chief of the Beijing
Research Center for Childhood Bacterial Diseases, an affiliate of the former CDC of China.
Dr. Yang has coordinated international collaborations with scientists in the U.S., Sweden, Finland, France, Russia and
Korea in the field of bacterial infections in childhood, especially Hib, Pneumococcus, Group A/B/G streptococcus,
MRSA, Pertussis, and Chlamydophila Pneumonia.
Dr. Yang continues to serve on numerous national and international committees on pediatric infectious diseases and
pediatric pulmonology. He served as president of the Chinese Subsociety of Pediatric Pulmolonogy for 15 years. He is
currently a member of EPI Committee of MOH of China, the Consultant of the Chinese Subsociety of Pediatric
Pulmolonogy. He is the Standing Committee member of Asian Society of Pediatric Infectious Diseases, ASPID) for 14
years. Since Oct 2014 he became President of ASPID. He was Board Member of WSPID from 2004-08.
Dr. Yang has been the recipient of several national and international awards, including the Aventis Pasteur Award from
the International Society of Infectious Diseases in 2000. In 2005, he was elected as a foreign member of the Russian
Academy of Medical Sciences. Dr. Yang has published more than 400 papers, reviews and book chapters, 110 of which
were published in peer-reviewed English journals.
58
Yunsong Yu
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University
Job title:
Vice President - Sir Run Run Shaw Hospital
Contact: yvys119@163.com
Areas of scientific expertise which are relevant to this call:
(1) Diagnosis and treatment of the infectious diseases (including caused by MDR、XDR、PDR pathogens);
(2) Bacterial resistance mechanism research (including carbapenem-resistant Enterobacteriaceae, carbapenem-resistant
Acinetobacter baumannii, extensive-drug resistant Pseudomonas aeruginosa, methicillin resistant Staphylococcus aureus,
vancomycin resistant Enterococcus, and so on);
(3) Surveillance and molecular epidemiology of nosocomial infections; (We have collected more than 20,000 clinical
Gram-negative bacilli strains, including A. baumannii, P. aeruginosa, E. coli and K. pneumoniae, from more than 60
hospitals in different regions of China, and built a MLST database for epidemiology study.)
(4)Research on the treatment options of the MDR、XDR、PDR infections.
Interests and potential opportunities to explore:
(1) Epidemiology and novel therapy method in blaKPC-producing K. pneumoniae and carbapenem-resistant A.
baumannii;
(2)Novel molecular mechanism of drug resistance in carbapenem-resistant Enterobacteriaceae or carbapenem-resistant A.
baumannii;
(3) Epidemiology and pathogenesis of disease caused by community-acquired methicillin resistant S. aureus;
(4) Pathogenesis of disease caused by hypervirulent K. pneumoniae.
59
Prof Yuxing Ni
The departments of clinical microbiology and Nosocomial infection control of Ruijin Hospital, Ruijin Hospital,
School of medicine, Shanghai Jiaotong University
Job title:
Professor of School of medicine, Shanghai Jiaotong University
Director- The departments of clinical microbiology and Nosocomial infection control of Ruijin Hospital
Contact: yuxing_ni@126.com
Areas of scientific expertise which are relevant to this call:
Clinical microbiology
Interests and potential opportunities to explore:
Bacteria resistance mechanism and the application of antibiotics
60
Prof Zhiyong Zong
West China Hospital, Sichuan University
Job title:
Professor of Center of Infectious Diseases, West China Hospital, Sichuan University
Director - Department of Infection Control, West China Hospital, Sichuan University
Contact: zhiyongz@scu.edu.cn
Areas of scientific expertise which are relevant to this call:
Infectious diseases, antimicrobial resistance, infection control
Interests and potential opportunities to explore:
1. Diagnosis and management of infectious diseases;
2. Mechanisms and dissemination of antimicrobial resistance (particularly, carbapenem-resistant Enterobacteriaceae,
multidrug-resistant Acinetobacter baumannii, Clostridium difficile);
3. Discovery of pathogen in infectious diseases using metagenomics;
4. Genomics for investigating outbreaks and tracking antimicrobial resistance;
5. Infection control.
61
Zongfu Mao
Wuhan University global health institute, School of Public Health, Wuhan University
Job title:
Dean of the school of Public Health, Wuhan University
Director- Wuhan University global health institute
Contact: zfmao@whu.edu.cn or zfmao@126.com
Professional Experience:
Jun., 2011- present: Director, Wuhan University global health institute;
May, 2007- present: Dean, School of Public Health Wuhan University;
Jun., 2001 - Apr., 2007: Deputy Dean, School of Public Health Wuhan University;
Oct., 1998 - present: School of Public Health Wuhan University Professor;
Mar., 2009 - Aug., 2011: Vice Mayor, Xianning City County Hubei Province, P.R.China (In Charge of Science and
Technology Bureau and Health Bureau of Xianning City);
Feb., 2003 - Dec., 2003: Associate Magistrate, Hongan County Hubei Province, P.R.China (In Charge of Education
Bureau and Health Bureau of Hongan County);
Jul., 1987 - Aug., 2000: Basic Medical College of Hubei Medical University, Assistant, Lecturer, Associate Professor
(Hubei Medical University Merged Wuhan University in 2000).
Memberships:
1. Member of the National People’s Congress, China;
2. Standing Council Member of Hubei Provincial of Chinese People’s Polictial Consultative Conference;
3. Vice President, China Medical Statistics Education Society;
4. Committeman and Secretary-general, China Pharmacoepidemiology Society;
5. Member of Editor Committee, Medical Journal of Chinese People Health;
6. Member of Editor Committee, Chinese Journal of Health Quality Management;
7. Associate Editor, Chinese Journal of Pharmaco-Epidemiology;
8. Member of Editor Committee, Chinese Journal of Epidemiology.
62