STUDY OF FIELD EFFECT TRANSISTORS ON LOADING WITH BIOLOGICAL MATERIAL IN ELECTROMAGNETIC FIELD Sarah Rizvi (1), Pallavi Purwar(2), V.R. Singh(3) National Physical Laboratory, Dr. K.S. Krishnan Marg, New Delhi-110012, India (1) rizvis@mail.nplindia.ernet.in, (2) purwar_pallavi@mail.nplindia.ernet.in, (3) vrsingh@mail.nplindia.ernet.in ABSTRACT The solid-state devices are very important in the instrumentation systems for various industrial, scientific and biomedical applications. With the ongoing miniaturisation trends, new devices of micro and nano sizes are now in use. Nanotechnology for the development of devices for new applications has progressed at a rapid speed in the recent past. In biomedical devices also, new types of microchips, biochips and sensing systems have been developed. Recently, the biological materials have been used in the devices like diodes, op amps, FETs. Some basic studies have been made on the physical, electrical and other properties for such devices. Acoustic stress effect and electromagnetic interference effect on the performance of solidstate devices have been reported. However, a systematic and detailed study is required to be made in biological environments. In the present work, study of solid-state devices with biological loading in RF field is pursued. FETs are chosen here, as these are very important in digital systems. The effect of loading the FET device with a biological material, in this case, bone material, is studied, the FETs use a gate element that when charged creates an electromagnetic field that changes the conductivity of a silicon channel and turns the transistor on or off. Investigations have been carried out by some of the researchers, on possible biological effects of exposure of devices to radio frequency and/or microwave radiation. The study on the influence of RF field on the performance of the devices has been of assistance to the scientific and industrial community, for making necessary improvement in the design of such devices. The performance characteristics of the device like current gain, power output, transconductance, pinch off voltage, saturated drain to source current, breakdown etc., have been analysed both under normal and under the influence of high frequency sources. The current-voltage parameters of the FETs are measured where the output drain current/voltage relationship is plotted at discrete gate voltage. The transfer characteristics that depict the variation in drain voltage due to variation in gate voltage, at some fixed drain voltage due in the saturation region are also measured. The study would assist in making necessary corrections in the device parameters under biological environment, particularly in precision instruments. INTRODUCTION Rapid advances in science and technology have provided a variety of semiconductor devices with highly controlled and unique properties, which enabled the fabrication of various functional devices. FETs and other devices coupled with biological materials are now useful in the development of biochips and micro-sensors. The integration of biomaterial with semiconductor devices greatly expands the impact of bioelectronics, and hence scientists have recently begun to extensively study these devices and to apply them to a variety of applications ranging from diagnosis of disease to gene therapies. A significant step has been taken in the direction of the study of these devices under biological influence. The radio frequency performance of a large variety of silicon devices has already been extensively studied for the realisation of high performance devices [1]. A variety of transistors and FETs etc. with performance adequate for practical applications at radio frequency have been reported [2,3]. The effect of RF power on biological tissues has also been widely investigated and documented [4]. However, a systematic and detailed study is required to be made to study the performance of these devices under the collective influence of a biological material and RF field. Here, the study of FETs on loading with biological material is made to ascertain the device response with and without RF field. 1 MATERIALS AND METHOD A basic n-channel depletion-mode field effect transistor with configuration, BFW 11, has been used in the present study. The in vitro animal bones are thoroughly washed and kept in saline solution for at least two days. Measurements have been made using finely ground powder and square shaped bone pieces (0.01x0.01 m2 approx.), after drying the solid samples for 10 days. In the present work, the effect of bone samples on the device performance has been studied in the frequency range 1 KHz – 15 MHz. The radio frequency has special biological significance since it can readily be transmitted through, absorbed by and reflected at biological sample boundaries in varying degrees. The FETs have been analysed using standard transistor characteristics and transfer characteristics (Fig.1) and also by connecting the device in the amplification mode (Fig.2). The investigation has been carried out by constructing a cell with parallel electrodes to apply the bone samples (moist in saline solution) as load at the gate terminal of the biasing circuit and a common source amplifier. The whole set-up is placed in field strength of 1.43x102 V/m, by constructing a condenser with aluminium conducting plates to which RF was applied. The temperature of the set-up is maintained in the range 18°-20°. 2 RESULTS AND DISCUSSION The absorption in the solid bone samples, below 20 MHz, is poor due to severe reflection and low electrical conductivity [5]. No change in device output is thus observed when the bone pieces are introduced at the gate terminal, both with and without field as shown in table 1, however bone powder shows considerable conductivity for the same conditions. Hence, the FETs have been analysed after loading with bone powder for frequencies less than 20 MHz. Since the gate terminal acts as the control element, the study is conducted by applying the load at the gate. A frequency dependent behaviour of the output parameter is observed for fixed values of drain and gate voltages, the current being maximum (0.38 mA for 40.2% w/v) at 7.7MHz (see Fig.3), as opposed to the conventional response of the device under similar conditions [6]. The way in which RF energy interacts with an object depends mainly on the field distributions within the material [4]. Hence, this response is explained by the interaction of RF with the bone sample, which results in rotation of dipole molecules at the frequency of applied electric field and hence affects the device characteristics. It has also been seen that after loading with different concentrations of bone powder, an increase in the concentration of the sample corresponds to increase in the value of current (Fig.4). This behaviour is because of change in the displacement current through the medium, which occurs as a result of change in physical properties of sample. The physical properties of bone depend on factors of physical geometry and dimensions, density, rigidity, hardness, mineral content, position and orientation of the fibres and hydration [7]. In the amplification mode, initially the device response has been computed as a function of frequency, without loading the FET. The gain of the amplifier reduces to zero when frequency is increased. However, when the sample is introduced at the gate as well as at the drain terminal of the device, the gain attains a constant value for frequencies beyond a particular value, depending upon sample w/v percentage, up to 15 MHz. A distinctive behaviour is also observed on loading with bone sample (> 37.5% w/v) at the drain terminal for 1KHz – 100 KHz as shown in the Fig.5. 0.40 -------> Drain Current (mA) 0.35 0.30 Table 1. Response of output voltage to change in weight of sample in amplification mode (without field) w = 1.0048 g Vds = 0.5 V Vgs = -3.0 V 0.25 0.20 2 Applied Field (AC) = 1.01x10 V/m 0.15 0.10 0.05 0.00 5 6 7 8 9 10 -------> Frquency (MHz) Fig.3. Frequency dependent behaviour of drain current with RF field 3 Weight of sample 0 0.939 1.005 1.124 1.5398 Output voltage (Vo), mV Bone Pieces Bone Powder 69.286 65.044 69.286 71.407 69.286 70.700 69.286 85.406 69.286 69.569 120 2.0 Vds = 0.5 v 110 120 2 Applied field = 1.01x10 V/m Frequency = 8 MHz 1.8 1.6 100 90 80 100 70 60 w = 1.0048 g 80 1.2 1.0 V0 (V) ---------> Idf/Ido --------> 1.4 w = 0.9385 g 0.8 0.6 at gate 50 at drain 0 20 40 60 80 100 60 40 20 w = 1.5398 g 0.4 0 0.2 0.0 -0.0 -0.5 -1.0 -1.5 -2.0 -2.5 100 -3.0 1000 10000 Frequency (KHz) --------> Fig.5. Output voltage of JFET amplifier on loading with bone powder at gate and drain terminal Vgs (V) -------> Fig.4. Idf/Ido vs. Vgs graphs for different weights CONCLUSION The radio frequency (RF) voltage gain and the drain current efficiency of field effect transistor (FET) devices have been improved by introducing the bone powder at the gate terminal of the FET circuit. The various output parameters of the FETs are studied under the combined influence of RF field and biological material, applied as load to the gate terminal of the circuit. The device with improved performance can be utilized in biomedical instrumentation as well as in various scientific applications. The present study would assist in understanding of interaction of biological material and/or RF field with the device. REFERENCES [1] F. Schwierz and J. J. Liou, “Semiconductor devices for RF applications: evolution and current status,” Microelectronics Reliability, vol. 41, pp. 145-168, February 2001. [2] K. Bladh, D. Gunnarsson, A. Aassime, M. Taslakov, R. Schoelkopf and P. Delsing, “Noise performance of the radiofrequency single-electron transistor,” Physica E: Low-dimensional Systems and Nanostructures, vol. 18, pp. 91-92, May 2003. [3] J. Robert, “High-frequency solid-state electronic devices,” IEEE Transactions on Electron Devices, vol. 52, pp. 638649, May 2005. [4] C. T. 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