Graham Young-Biography Professor, School of Aquatic and Fishery Sciences, University of Washington Executive Director, Western Regional Aquaculture Center EDUCATION 1975 BSc, University of Sheffield, England Major: Zoology 1980 PhD, University of Sheffield, England Major: Zoology PROFESSIONAL EXPERIENCE 1980-1982 Postdoctoral Fellow, National Institute for Basic Biology, Okazaki, Japan 1982-84 Graduate Research Zoologist, University of California, Berkeley, CA 1984-89 Assistant Research Zoologist, University of California, Berkeley, CA 1989-2002 Lecturer, Senior Lecturer and Associate Professor, Department of Zoology, University of Otago, New Zealand 2002-2004 Associate Professor, Department of Biological Sciences, University of Idaho 2002-2007 Adjunct Associate Professor, Department of Zoology, University of Otago, New Zealand 2002-present Faculty (2002-2004) and Adjunct Faculty (2004 to present), Center for Reproduction, Washington State University/University of Idaho 2004-present Professor, School of Aquatic and Fishery Sciences, University of Washington 2004-present Executive Director, Western Regional Aquaculture Center SYNERGISTIC ACTIVITIES 1989-2002 Member of Council (1989-2002) and Treasurer (1996-2000), Asia and Oceania Society for Comparative Endocrinology 1997-present Member of Steering Committee, Reproductive Biology in Aquaculture Program of the International Union of Biological Sciences 2001 Member of the International Advisory Board, 7th International Symposium on Reproductive Physiology of Fish 2004 Co-organizer of symposium “Advances in Fish Reproduction and Biotechnology”, Annual Meeting of the Society for the Study of Reproduction, Vancouver, Canada 2005 External Review Team member and Chair of the Graduate Program Review Committee, Department of Zoology, North Carolina State University 2005-2009 External Review Panel member, Washington-Idaho Aquaculture Initiative (USDA-funded) 2007 Regional Aquaculture Center Representative, Steering Committee for the National Aquaculture Extension Conference 2008-2010 Faculty Mentor, Ocean and Coastal Interdisciplinary Science (OACIS) GK-20 Program 2008-2010 Faculty Mentor, University of Washington NSF GK-12 Program 2008 Chair, International Organizing Committee, International Symposium on Sex Determination and Gametogenesis in Fish: Current Status and Future Challenges, Honolulu HI 2011 NSF Panel Member, Physiological and Structural Systems Cluster 2012 National Sea Grant National Marine Aquaculture Initiative Preproposal Review Panel member 2011-2013 2013 Host/Mentor, International Cooperative Research Project on the Molecular Mechanisms Regulating Reproduction in Fish, Japan Society for the Promotion of Science External review panel member, University of Idaho Aquaculture Research Institute PUBLICATIONS (selected) Young, G., Lokman, P.M., Kusakabe, M., Nakamura, I. and Goetz F.W. Gonadal steroidogenesis in teleost fish. In Molecular Aspects of Fish and Marine Biology (C. Hew series ed.), volume 2 (N. Sherwood and P. Melamed eds), pp. 155-223. World Scientific Press, Singapore (2005). Kusakabe, M., Zuccarelli, M.D., Nakamura, I, Young, G. Steroidogenic acute regulatory protein in white sturgeon (Acipenser transmontanus): cDNA cloning, sites of expression and transcript abundance in corticosteroidogenic tissue after an acute stressor. General and Comparative Endocrinology 162: 233–240 (2009) Nakamura, I, Kusakabe, M., Young, G. Differential suppressive effects of low physiological doses of estradiol-17β in vivo on levels of mRNAs encoding steroidogenic acute regulatory protein and three steroidogenic enzymes in previtellogenic ovarian follicles of rainbow trout. General and Comparative Endocrinology 163: 318-323 (2009) Lubzens, E., Young, G., Bobe, J. and Cerdà, J. Oogenesis in teleosts: how fish eggs are formed. General and Comparative Endocrinology 165:367-389 (2010) Beaudreau, A.H., Andrews, K.S. , Larsen, D.A., Young, G., Beckman, B. Variation in plasma levels of insulin-like growth factor-I (IGF-I) in lingcod: relationships among season, size, and gonadal steroids. Marine Biology 158:439-450 (2011). McQuillan, H.J., Kusakabe, M., Young, G. Effects of chronic manipulation of adrenocorticotropic hormone levels in Chinook salmon on expression of interrenal steroidogenic acute regulatory protein and steroidogenic enzymes. General and Comparative Endocrinology 174: 156-165 (2011) Miura, C., Shimizu, Y., Uehara, M., Ozaki, Y., Young, G., Miura, T. Gh is produced by the testis of Japanese eel and stimulates proliferation of spermatogonia. Reproduction 142: 869–877 (2011) Yamamoto, Y., Luckenbach, A.J., Goetz, F.W., Young, G., and Swanson, P. Disruption of the salmon reproductive endocrine axis through prolonged nutritional stress: changes in circulating hormone levels and transcripts for ovarian genes involved in steroidogenesis and apoptosis. General and Comparative Endocrinology 172: 331-343 (2011) Forsgren, K.L. and Young, G. 2012. Stage-specific effects of androgens and estradiol-17β on the development of late primary and early secondary ovarian follicles of coho salmon (Oncorhynchus kisutch) in vitro. Biology of Reproduction 87: 1-14 (2012) Shibata, Y., Iwamatsue, T., Suzuki, N., Young, G., Naruse, K., Nagahama, Y. and Yoshikuni, M. An oocyte-specific astacin family protease, alveolin, is released from cortical granules to trigger egg envelope hardening during fertilization in medaka (Oryzias latipes). Developmental Biology 372: 239-248 (2012). Baker M.R, Swanson, P. and Young, G. Injuries from non-retention in gillnet fisheries suppress reproductive maturation in escaped fish. PLOS One 8: e69615 (2013). Harding, L.A., Schultz, I.R., Goetz, G.W., Luckenbach, J.A., Young, G., Goetz, F.W., Swanson, P. High-throughput sequencing and pathway analysis reveal alteration of the pituitary transcriptome by 17a-ethynylestradiol (EE2) in female coho salmon, Oncorhychus kisutch. Aquatic Toxicology 142-143: 146-163 (2013).