Report 05070 GE LightSpeed RT CT scanner technical evaluation November 2005 www.pasa.nhs.uk/cep Health and social care working together About evaluation reports The Centre for Evidence-based Purchasing provides independent and objective evaluations of medical devices available on the UK market. Specialist centres, mainly in NHS Trusts, do the evaluations under contract to the NHS Purchasing and Supply Agency (NHS PASA). Results are available on our website (www.pasa.nhs.uk/cep). Our evaluations are usually of products supplied by the manufacturer. We expect these products to be representative of those on the market but cannot guarantee this. Prospective purchasers should satisfy themselves about any modifications that might have been made after our evaluation. The Centre for Evidence-based Purchasing (formerly the Device Evaluation Service) transferred from the Medicines and Healthcare products Regulatory Agency to NHS PASA on 1 September 2005. 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GE LightSpeed RT CT scanner technical evaluation Assessed at Weston Park Hospital, Sheffield, UK, November 2004 David Platten Nicholas Keat, Maria Lewis, Sue Edyvean ImPACT Bence Jones Offices St George’s Hospital London SW17 0QT Tel: 020 8725 3366 Fax: 020 8725 3969 Report 05070: GE LightSpeed RT CT scanner technical evaluation e-mail: impact@impactscan.org For more information on ImPACT visit www.impactscan.org © Crown Copyright 2005 Apart from any fair dealing for the purposes of research or private study, or criticism, or review, as permitted under the Copyright, Designs & Patents Act, 1998, this publication may only be reproduced, stored, or transmitted in any form or by any means with the prior permission, in writing, of the Controller of Her Majesty’s Stationery Office (HMSO). Information on reproduction outside these terms can be found on the HMSO website (www.hmso.gov.uk) or e-mail: hmsolicensing@cabinet-office.x.gsi.gov.uk. Contents Contents .....................................................................................................4 Summary.....................................................................................................5 GE LightSpeed RT.........................................................................................5 Clinical scans .............................................................................................6 Dose and image quality.............................................................................7 Scanner Q2 values.........................................................................................8 Image noise ................................................................................................9 Variation of image noise with scan parameters.............................................9 Variation of image noise with reconstruction filter .......................................10 Inter-slice noise variation.............................................................................11 CT number accuracy and uniformity .....................................................12 CT number accuracy and uniformity............................................................12 CT number and electron density linearity....................................................14 Spatial resolution.....................................................................................15 Variation of spatial resolution with scan parameters ...................................15 Spatial resolution and image noise..............................................................16 Limiting resolution and comparison with GE data .......................................17 Slice width characteristics......................................................................18 Imaged slice thickness: axial .......................................................................18 Imaged slice thickness: helical ....................................................................19 Report 05070: GE LightSpeed RT CT scanner technical evaluation Extended field of view .............................................................................20 Extended field of view..................................................................................20 Patient couch movement ........................................................................22 Z-axis couch movement accuracy under scanner control ...........................22 Couch deflection under load........................................................................22 Radiation dose .........................................................................................23 CTDI100 in air................................................................................................23 CTDI100 and CTDIw in acrylic phantoms .....................................................24 X-ray beam width.........................................................................................25 Z-axis geometric efficiency ..........................................................................25 Low contrast detectability.......................................................................26 Appendix 1. Scanner specifications ......................................................27 Appendix 2. Manufacturer’s comments.................................................39 Appendix 3. Image quality assessment and Q......................................40 Appendix 4. ImPACT................................................................................41 ImPACT .......................................................................................................41 Support to purchasers and users ................................................................41 Summary GE LightSpeed RT The GE LightSpeed RT is a third generation 4-slice helical CT scanner with a gantry opening that is wider than those found on standard diagnostic CT systems. A generator rating of 53.2 kW enables a maximum current of 440 mA at 120 kV. Rotation times of 1, 2, 3 and 4 seconds are available. Routine beam collimations available from the system’s 20 mm, 16 x 1.25 mm element detector bank are 4 x 1.25, 4 x 2.5, 4 x 3.75 and 4 x 5 mm. Narrow collimations of 2 x 0.625 and 1 x 1.25 mm are also available (see Figure 1). Figure 1. LightSpeed RT z-axis detector layout Report 05070: GE LightSpeed RT CT scanner technical evaluation 16 x 1.25 mm z-axis The wide gantry aperture of 80 cm allows flexibility with patient scanning position, in particular for patients being scanned as part of the radiotherapy treatment planning process. Other applications include the scanning of obese patients, trauma patients who may be attached to life support equipment, and interventional procedures where easy patient access is particularly important. In addition to having a larger gantry bore, the RT also allows images to be reconstructed with a larger field of view than a standard CT system. Traditional reconstruction methods on the RT allow images up to 50 cm to be reconstructed. In addition, extended field of view reconstruction enables images with a field of view of 65 cm to be generated. These images can be used to visualise anatomy that lies beyond the standard 50 cm field of view, again helpful for radiotherapy treatment planning. However, it should be noted that the portion of the image in the extended field of view will have a reduced image quality with respect to spatial resolution, noise and CT number accuracy, compared to that in the primary field of view. 5 Clinical scans The scan settings chosen for the six clinical scans, defined in ImPACT report MDA/98/25, were given by GE for the LightSpeed RT, and said by GE to be representative of protocols in clinical use. In addition, helical protocols for head and abdomen were used. Results in italics are mean results for the following four-slice CT scanners: GE LightSpeed RT, GE LightSpeed Plus, Philips Mx8000, Siemens Sensation 4 and Toshiba Aquilion. Note that the mean z-sensitivity figures may be a result of collimations that differ from those used for the LightSpeed RT (see Table 1). Table 1. Clinical scan tables 250 120 Helical brain 120 200 1 5 (4 x 2.5) Inner ear 140 120 1 0.63 (2 x 0.63) 270 1 Helical inner ear 140 70 1 0.63 (2 x 0.63) Axial abdomen 120 190 1 5 (4 x 5) Helical abdomen 120 Low noise spine 120 High res spine 120 250 290 200 1 1 1 5 (4 x 5) 0.75 1 1.5 SOFT 250 SOFT 120 EDGE 120 EDGE 380 STANDARD 380 2.5 (4 x 2.5) 120 1.25 (4 x 1.25) 120 6 STANDARD STANDARD BONE+ MTF10 (c/cm) 5 (4 x 5) Standard brain MTF50 (c/cm) SOFT Pitch 250 Noise (HU) 5 (4 x 5) Z-sens (mm) Slice thickness (mm) (Collimation (# x mm)) 1 Recon filter Time (s) 320 Recon FOV (mm) mA kV Report 05070: GE LightSpeed RT CT scanner technical evaluation Post fossa 120 Results CTDIvol (mGy) Scan parameters Scan 56.8 4.7 2.6 3.1 5.7 54.9 4.6 3.2 3.2 5.9 47.9 4.7 2.8 3.1 5.7 46.9 6.3 2.9 3.1 5.8 52.7 4.9 2.6 3.2 5.8 43.5 0.9 97 7.8 13.4 51.2 0.8 141 9.1 14.4 25.4 1.0 111 6.3 11.9 16.2 4.7 22 3.9 6.3 15.4 6.6 21 3.8 6.3 14.8 6.4 20 3.8 6.5 15.8 6.5 19 3.7 6.4 29.9 2.3 26 3.5 6.1 32.1 2.4 25 3.7 6.3 24.4 1.1 257 7.8 10.8 30.5 1.7 181 7.6 11.0 Dose and image quality Dose efficiency is a term used to describe the quality of a scanner’s images relative to the radiation dose to the patient. It can be expressed in a number of ways, and ImPACT use the ‘Q value’, which combines measurements of noise, high contrast resolution, slice thickness and dose to produce an imaging figure of merit (see Appendix 3 for more details). The Q2 values presented in this section (see Table 2 and Table 3) are for head and body imaging. Standard acquisition and reconstruction parameters are used where possible to minimise slight variations that occur for different kV, slice thickness, scan time and reconstruction filter. These standard settings are listed below: • • • • • Report 05070: GE LightSpeed RT CT scanner technical evaluation • • Tube voltage: 120 kV or 130 kV when this is the ‘standard’ operating kV for the scanner Collimation: 20 mm, or the closest available setting Image width: 5 mm, or the closest available setting Scan time: as recommended by the manufacturer, sub-second for body scanning and 1 s or greater for head scanning Reconstruction filter: the one that most closely matches the average ‘standard’ head and body filter (MTF50 of 3.4 c/cm, MTF10 of 6.0 c/cm) Reconstruction field of view: 250 mm (head) and 380 mm (body) Small focal spot size. The mAs setting that would result in a CTDIvol of 50 mGy for head and 15 mGy for body scanning is listed. Z-sensitivity, image noise at 50 or 15 mGy, and MTF values are also shown. Mean Q2 values are for the following four-slice CT scanners: GE LightSpeed RT, GE LightSpeed Plus, Philips Mx8000, Siemens Sensation 4 and Toshiba Aquilion. 7 Dose and image quality Scanner Q2 values Table 2. Q2 value for head scanning Scanner Filter GE LightSpeed RT SOFT Mean mAs for z-sens Noise 50 mGy (mm) (HU) MTF50 MTF10 (c/cm) (c/cm) Q2 253 4.7 3.4 3.2 5.8 5.9 269 4.7 3.7 3.4 6.2 5.8 MTF50 MTF10 (c/cm) (c/cm) Table 3. Q2 value for body scanning Scanner Filter GE LightSpeed RT SOFT Q2 151 4.7 20 3.5 6.0 2.0 165 6.5 18 3.5 6.0 2.0 Report 05070: GE LightSpeed RT CT scanner technical evaluation Mean mAs for z-sens Noise 15 mGy (mm) (HU) 8 Image noise Variation of image noise with scan parameters Table 4 shows the effect of varying scan parameters upon image noise in uniform head and body sized water phantoms. Relative noise values are quoted, as different phantoms will result in different absolute values of noise, however the relative values should be similar. The bold figures in the relative noise columns show the standard setting to which other values have been normalised. The adjusted relative noise column shows the deviation from the expected noise value, due to the change in acquisition parameters. Standard axial scan parameters are 120 kV, 270 mA, 1 s scan time, 20 mm collimation resulting in 4 x 5 mm images. The SOFT reconstruction filter was used. Report 05070: GE LightSpeed RT CT scanner technical evaluation Table 4. Variation of image noise with scan parameters Parameter Setting Relative noise Adjusted relative noise mA 10 20 40 80 160 270 440 6.06 4.05 2.76 1.90 1.31 1.00 0.77 1.17 1.10 1.06 1.03 1.01 1.00 0.98 1 2 3 4 1.25 (1 x 1.25) 1.25 (2 x 0.625) 5 (4 x 1.25) 10 (4 x 2.5) 15 (4 x 3.75) 1.00 0.70 0.57 0.50 2.03 2.65 2.04 1.41 1.15 1.00 0.99 0.99 1.01 1.01 0.94 1.02 1.00 1.00 20 (4 x 5) 5 (2 x 2.5) 10 (2 x 5) 15 (2 x 7.5) 20 (2 x 10) 5 (1 x 5) 10 (1 x 10) 1.00 1.44 0.99 0.81 0.70 1.00 0.69 1.00 1.02 0.99 1.00 0.99 1.00 0.98 Scan time (s) Collimation (mm) (# x mm) 9 Image noise Variation of image noise with reconstruction filter Results are acquired using head and body sized uniform water phantoms (see Table 5). Scans are axial, parameters are: 120 kV, 320 mA, 1 s scan time, 20 mm collimation resulting in 4 x 5 mm images. Table 5. Variation of image noise with reconstruction filter Parameter Recon. filter (head) Report 05070: GE LightSpeed RT CT scanner technical evaluation Recon. filter (body) Setting Relative noise SOFT STANDARD LUNG DETAIL BONE EDGE BONEPLUS SOFT STANDARD LUNG DETAIL BONE EDGE BONEPLUS 1.00 1.26 5.85 1.80 5.39 10.61 7.81 1.00 1.27 5.86 1.80 5.40 10.58 7.82 10 Image noise Inter-slice noise variation Axial scans were made of ImPACT’s head phantom, and the noise from each slice in a 4 x 5 mm and 4 x 1.25 mm slice acquisition was compared (see Table 6 and Table 7). Results are for 120 kV, 270 mA, 1 s scan time and SOFT reconstruction filter. Table 6. Variation of noise in each slice in a 4 x 5 mm axial acquisition Detector group Noise (HU) Variation from mean (%) 1 2 3 4 Mean 2.96 2.85 2.52 2.74 2.77 6.8 3.1 -8.9 -1.0 - Results are for 120 kV, 200 mA, 1 s scan time and SOFT reconstruction filter. Report 05070: GE LightSpeed RT CT scanner technical evaluation Table 7. Variation of noise in each slice in a 4 x 1.25 mm axial acquisition Detector group Noise (HU) Variation from mean (%) 1 2 3 4 Mean 7.70 7.89 7.71 8.05 7.84 -1.7 0.6 -1.6 2.7 - 11 CT number accuracy and uniformity CT number accuracy and uniformity CT number accuracy and uniformity was assessed in ImPACT’s standard head (185 mm diameter) and body (340 mm diameter) phantoms. The head phantom has a bone equivalent shell to mimic a patient’s skull. Regions of interest were placed at the centre of the phantom, and also at four positions 1 cm in from the inside of the periphery of the phantoms corresponding to north, east, south and west compass points. Acquisition parameters for head scanning were 120 kV, 200 mA, 1 s scan time, 1 x 5 mm slice, SOFT filter, 250 mm scan and reconstruction field of view (see Table 8). Report 05070: GE LightSpeed RT CT scanner technical evaluation Table 8. CT number accuracy and uniformity for head scanning Position CT number Difference from centre (HU) Centre N E S W -1.24 0.96 1.10 1.09 1.10 2.20 2.34 2.33 2.34 Acquisition parameters for body scanning were 120 kV, 190 mA, 1 s scan time, 1 x 5 mm slice, SOFT filter, 500 mm scan field of view and 380 mm reconstruction field of view (see Table 9). Table 9. CT number accuracy and uniformity for body scanning Position CT number Difference from centre (HU) Centre N E S W 1.96 0.56 1.44 1.74 1.48 -1.40 -0.52 -0.22 -0.48 12 CT number accuracy and uniformity In addition to the head and body phantoms, a uniform 480 mm diameter water phantom was scanned. This phantom is larger than a standard patient, and fills the entire standard field of view to within a 10 mm radius. Acquisition parameters for the 480 mm phantom were 120 kV, 200 mA, 1 s, 1 x 5 mm slice, SOFT filter (axial scan). The acquisition parameters for head and body as given for Table 8 and Table 9. Figure 2 shows the variation of CT number across the field of view for all three phantoms. Annular (ring-shaped) ROIs are used with dimensions of 0-10 %, 1020 % …. 80-90 % of the phantom’s internal diameter. Acquisition parameters for the 480 mm phantom were 120 kV, 200 mA, 1 s, 1 x 5 mm slice, SOFT filter (axial scan). The acquisition parameters for head and body as given for Table 8 and Table 9. Figure 2. CT number in annular ROI at increasing diameter from the isocentre for head, body and 480 mm phantoms 15 CT number (HU) Report 05070: GE LightSpeed RT CT scanner technical evaluation 10 5 0 -5 Head Body Large FOV -10 -15 0 40 80 120 160 200 240 280 320 ROI Diameter (mm) 13 360 400 440 480 CT number accuracy and uniformity CT number and electron density linearity An RMI 467 electron density phantom was scanned with 200 mA, 1 s scan time, 1 x 5 mm slice, SOFT filter and a range of kV settings (see Figure 3). Figure 3. CT number against electron density at a range of kVs 2000 80 kV 100 kV 120 kV 140 kV CT number (HU) 1500 1000 500 0 Report 05070: GE LightSpeed RT CT scanner technical evaluation -500 -1000 0.0 0.2 0.4 0.6 0.8 1.0 1.2 Relative electron density 14 1.4 1.6 1.8 Spatial resolution Variation of spatial resolution with scan parameters Spatial resolution is characterised by the average of the MTF50 and MTF10 values, the frequencies corresponding to the 50 % and 10 % modulation transfer function values respectively (in cycles per cm). Acquisition parameters were 120 kV, 1 s scan time, head mode, 10 mm collimation resulting in 4 x 2.5 mm images. 200 mA was used for small focal spot, and 300 mA for large focus (see Table 10). Table 10. Variation of spatial resolution with scan parameters Parameter Report 05070: GE LightSpeed RT CT scanner technical evaluation Small focus Large focus Scan type Setting MTF50 (c/cm) MTF10 (c/cm) SOFT STANDARD LUNG DETAIL BONE EDGE BONEPLUS SOFT STANDARD LUNG DETAIL BONE EDGE BONEPLUS Axial (SOFT) Helical (SOFT) 3.2 3.6 7.3 4.0 7.0 7.8 9.3 3.1 3.4 7.1 3.8 6.3 8.1 8.8 3.2 3.2 5.8 6.5 8.3 8.0 11.0 13.4 12.0 5.7 6.4 8.3 7.8 11.3 12.8 11.6 5.8 5.8 15 Spatial resolution Spatial resolution and image noise Figure 4 and Figure 5 show image noise and spatial resolution values for each reconstruction filter, in head and body scanning respectively. Head scan conditions are 120 kV, 253 mA, 1 s scan time, 4 x 5 mm collimation resulting in a CTDIvol of 50 mGy. Body scan conditions are 120 kV, 151 mA, 1 s scan time, 4 x 5 mm collimation resulting in a CTDIvol of 15 mGy. Spatial resolution is characterised by the average of the MTF50 and MTF10 values. Figure 4. Image noise against spatial resolution for head scanning 35 30 SOFT LUNG BONE BONEPLUS Image Noise (HU) 25 STANDARD DETAIL EDGE 20 15 Report 05070: GE LightSpeed RT CT scanner technical evaluation 10 5 0 0 2 4 6 8 Mean MTF50 and MTF10 (c/cm) 16 10 12 Spatial resolution Figure 5. Image noise against spatial resolution for body scanning 140 120 STANDARD LUNG DETAIL BONE EDGE BONEPLUS 100 Image Noise (HU) SOFT 80 60 40 20 0 0 2 4 6 8 10 12 Report 05070: GE LightSpeed RT CT scanner technical evaluation Mean MTF50 and MTF10 (c/cm) Limiting resolution and comparison with GE data ImPACT used settings of 120 kV, 200 mA, 3 s scan time, 10 mm collimation, resulting in 4 x 2.5 mm images. A scan and reconstruction field of view of 120 mm was used, together with the EDGE reconstruction filter (see Table 11). Table 11. Limiting spatial resolution MTF50 MTF10 MTF0 (GE), MTF2 (ImPACT) GE (c/cm) ImPACT (c/cm) 10.5 13.9 15.4 8.6 13.2 14.4 17 Slice width characteristics Imaged slice thickness: axial Measured using 50 µm titanium ramps inclined at 30° to the scan plane, at the centre of the field of view (see Table 12 to Table 15). Table 12. Axial slice thickness, small focal spot Nominal slice (mm) (# x mm) Report 05070: GE LightSpeed RT CT scanner technical evaluation 0.625 (2 x 0.625) 1.25 (1 x 1.25) 1.25 (4 x 1.25) 2.5 (4 x 2.5) 3.75 (4 x 3.75) 5 (4 x 5) 2.5 (2 x 2.5) 5 (2 x 5) 7.5 (2 x 7.5) 10 (2 x 10) 5 (1 x 5) 10 (1 x 10) Measured slice (mm) Ratio (measured:nominal) 0.93 1.1 1.1 2.4 3.6 4.7 2.3 4.9 7.3 9.6 4.8 9.8 0.74 0.89 0.88 0.96 0.95 0.93 0.93 0.97 0.97 0.96 0.97 0.98 Table 13. Axial slice thickness, large focal spot Nominal slice (mm) (# x mm) 1.25 1.25 2.5 3.75 5 2.5 5 7.5 10 5 10 (1 x 1.25) (4 x 1.25) (4 x 2.5) (4 x 3.75) (4 x 5) (2 x 2.5) (2 x 5) (2 x 7.5) (2 x 10) (1 x 5) (1 x 10) Measured slice (mm) Ratio (measured:nominal) 1.1 1.1 2.3 3.5 4.7 2.4 4.8 7.2 9.6 4.8 9.7 0.86 0.90 0.94 0.94 0.94 0.95 0.96 0.96 0.96 0.97 0.97 18 Slice width characteristics Table 14. Variation of axial slice thickness with detector group, 4 x 5 mm, large focal spot Detector group Measured slice (mm) Variation from mean (%) 1 2 3 4 Mean 4.60 4.87 4.78 4.48 4.68 -1.9 4.0 2.2 -4.3 - Report 05070: GE LightSpeed RT CT scanner technical evaluation Table 15. Variation of axial slice thickness with detector group, 4 x 1.25 mm, large focal spot Detector group Measured slice (mm) Variation from mean (%) 1 2 3 4 Mean 1.14 1.13 1.13 1.10 1.12 1.5 0.2 0.3 -1.9 - Imaged slice thickness: helical Measured using a 6 mm diameter, 50 µm thick gold disc, 15 mm from the centre of the field of view. The full width at half maximum (FWHM) of the z-sensitivity profile is quoted to characterise the slice thickness (see Table 16). Table 16. Helical slice thickness (z-sensitivity) Collimation (mm) (# slices x slice width) Mode (pitchx) Table feed (mm/rotation) Nominal image thickness (mm) Z-sensitivity (FWHM) (mm) Ratio actual:nominal 20 (4 x 5) 20 (4 x 5) 20 (4 x 2.5) 20 (4 x 2.5) 0.75 1.5 0.75 1.5 15 30 15 30 5 5 2.5 2.5 5.1 6.4 2.5 3.2 1.0 1.3 1.0 1.3 19 Extended field of view Extended field of view In order to reconstruct a CT image, attenuation data is normally required through an object at all angles during the scanner’s rotation. The image field of view is therefore limited by the detector fan angle, and the geometry of the scanner (see Figure 6). Figure 6. LightSpeed RT standard and extended fields of view Extended field of view Standard field of view Report 05070: GE LightSpeed RT CT scanner technical evaluation Gantry bore The LightSpeed RT has a standard field of view of 500 mm. It can also reconstruct images with a 650 mm diameter using extrapolated attenuation measurements (Figure 6).Applications for this extended field of view include the scanning of radiotherapy and very large patients. A water filled cylinder of 94 mm diameter containing a 10 mm diameter Teflon rod was used to represent an arm. This was positioned in the scanner next to ImPACT’s body sized water phantom and scanned at various distances from the body phantom to simulate the presence of an arm in the extended field of view. Figure 7(a) shows the body phantom without the simulated arm present. Figure 7(b) has the arm alongside the body phantom. The outline of the arm is well defined, and the CT number of the water in the arm is close to 0 HU. Artefact is visible around the Teflon insert in Figure 7(c). Also, the CT number of the water in the arm has dropped by 200 HU. In the small portion of the arm present with in the reconstructed field of view in Figure 7(d) there is a further drop in CT number of the water, and some geometric distortion of the arm outline. 20 The CT number of the water in the body phantom is constant in each image, and unaffected by the presence of the arm. Figure 7. Images with simulated arm in extended field of view, all at image fields of view of 650 mm (b) arm on border of 500 mm field of view (c) arm on border of 650 mm field of view (d) arm almost outside 650 mm field of view Report 05070: GE LightSpeed RT CT scanner technical evaluation (a) no ‘arm’ 21 Patient couch movement Z-axis couch movement accuracy under scanner control The couch was loaded with approximately 70 kg, and a rod of known dimensions containing calibrated incremental markers was scanned helically. 1.25 mm images were reconstructed at 0.63 mm intervals at each end of the rod. The z-axis positions of the images showing the first and last calibrated markers on the rod were 133.98 and 33.98, giving a measured distance of 100 mm between markers which were known to be 100 mm apart. Couch deflection under load Report 05070: GE LightSpeed RT CT scanner technical evaluation The couch top was scanned with the loaded couch at zero z-position. The couch was then moved 112.9 cm into the gantry, as indicated by the scanner. The scan was repeated in this extended position. Using the images, the vertical position of the couch top was measured for the two couch positions. The loaded couch was shown to deflect vertically by 1.9 mm at the scan plane in the course of moving 112.9 cm. 22 Radiation dose CTDI100 in air Table 17 shows CTDI100 measured at the scan isocentre using 200 mA, 1 s scan time and 1 x 10 mm collimation. Table 17. CTDI100 in air kV CTDI100 (head) (mGy/100mAs) CTDI100 (body) (mGy/100mAs) 80 100 120 140 13.2 21.1 30.2 42.1 9.2 15.9 23.9 34.6 Table 18 shows relative CTDI100 values per 100 mAs, measured at 120 kV and 200 mA. Table 18. Variation of CTDI100 with scan parameters Parameter Report 05070: GE LightSpeed RT CT scanner technical evaluation Focal spot Collimation (mm) (# slices x slice width) Scan time (s) Setting Relative CTDI100 Small Large 1.25 (1 x 1.25) 1.25 (2 x 0.63) 5 (1 x 5) 10 (1 x 10) 15 (2 x 7.5) 20 (4 x 5) 1 2 3 4 1.00 1.04 2.44 1.28 1.24 1.00 0.93 0.86 1.00 1.00 1.00 1.00 23 Radiation dose CTDI100 and CTDIw in acrylic phantoms Measured in 160 mm and 320 mm diameter CTDI phantoms for head and body fields of view (FOV) respectively. Scan parameters are 120 kV, 200 mA, 1 s scan time and 1 x 10 mm collimation (see Table 19 to Table 21). Table 19. CTDI100 and CTDIw in acrylic phantoms, head FOV kV CTDICentre (mGy/100mAs) CTDIPeriphery (mGy/100mAs) CTDIW (mGy/100mAs) 80 100 120 140 6.9 12.6 19.3 28.0 7.9 13.5 20.1 28.7 7.6 13.2 19.8 28.5 Report 05070: GE LightSpeed RT CT scanner technical evaluation Table 20. CTDI100 and CTDIw in acrylic phantoms, body FOV kV CTDICentre (mGy/100mAs) CTDIPeriphery (mGy/100mAs) CTDIW (mGy/100mAs) 80 100 120 140 1.6 3.3 5.6 8.7 4.3 7.8 12.1 17.7 3.4 6.3 9.9 14.7 Table 21. ImPACT and manufacturer dose comparison at 120 kV ImPACT figures are for 4x5 mm collimation, large focus Phantom, position ImPACT CTDI100 (mGy/100mAs) GE CTDI100 (mGy/100mAs) Head, centre 17.3 Head, periphery 18.0 Head, weighted 17.8 Body, centre 5.0 Body, periphery 10.8 Body, weighted 8.9 * GE's CTDI specification is currently under review 24 * * * * * * Ratio ImPACT:GE * * * * * * Radiation dose X-ray beam width X-ray beam profiles measured with radiotherapy verification film at the centre of the field of view. Films were read with a scanning densitometer (see Table 22). Table 22. Irradiated length, large focal spot Collimation (mm) Irradiated FWHM (mm) (# slices x slice width) 1.25 1.25 5 10 15 20 (2x0.63) (1x1.25) (4x1.25) (4x2.5) (4x3.75) (4x5) Ratio (irradiated:nominal) 2.1 3.6 7.1 11.5 16.3 20.0 1.65 2.89 1.42 1.15 1.09 1.00 Z-axis geometric efficiency Geometric efficiency is expressed as the percentage of the x-ray beam exposure falling within the nominal collimated slice width (see Table 23). Report 05070: GE LightSpeed RT CT scanner technical evaluation Table 23. Geometric efficiency, large focal spot Collimation (mm) (# slices x slice width) 1.25 1.25 5 10 15 20 (2x0.63) (1x1.25) (4x1.25) (4x2.5) (4x3.75) (4x5) Geometric efficiency (%) 55 34 70 85 91 97 25 Low contrast detectability The low contrast section of a Catphan™ 500 was scanned, as shown in Figure 8. The 0.3% (3 HU) contrast details scored for the smallest visible detail in 20 images by 4 observers. The detail size quoted in Table 24 is the smallest detail that was seen in at least 50% of the images viewed by the observers. Scanning conditions were 120 kV, 200 mA, 1 s scan time, 2 x 10 mm collimation, 10 mm image, SOFT reconstruction filter. This results in a CTDI at the surface of the Catphan™ of 25 mGy. The GE figures use 120 kV, 135 mAs, 10 mm image and STANDARD reconstruction filter. They are obtained from a statistical not visual analysis. Table 24. Low contrast detectability Smallest visible Nominal contrast detail (mm) (HU) ImPACT GE (statistical) 5 5 3 3 Surface dose (mGy) 25 13.3 Report 05070: GE LightSpeed RT CT scanner technical evaluation Figure 8. Catphan™ low contrast section on LightSpeed RT, displayed with window level 50 HU, window width 30 HU 26 Appendix 1. Scanner specifications Table 25. Couch GE LightSpeed RT Couch top material Carbon fibre Couch top length and width (cm) 239 x 42 Horizontal movement range (cm) 170 Horizontal movement speeds (mm/sec) up to 100 Accuracy/reproducibility of table positioning (mm) ± 0.25 Scannable horizontal range without table top extension (cm) 170 (Axial), 160 (Helical & Scout) Scannable horizontal range with table top extension(s) (cm) 170 (Axial), 160 (Helical & Scout) Vertical movement range out of gantry (cm) 51 - 99 Vertical movement range in gantry (cm) 72.8 - 99.1 Minimum couch top height outside gantry (cm) 51 Maximum weight allowed on couch (kg) 205 Report 05070: GE LightSpeed RT CT scanner technical evaluation Maximum weight on couch which still achieves stated performance specifications (kg) 180 (±0.25mm) 205 (±1mm) Table 26. Scanner gantry GE LightSpeed RT Generation 3rd Slipring Low voltage Aperture (cm) 80 Scan fields of view (cm) 25 and 50 Tilt range (degrees) ± 30 Type of positioning lights Laser Accuracy of positioning lights (mm) ± 1 at any laser to patient distance 27 Appendix 1. Scanner specifications Table 27. X-ray generator GE LightSpeed RT Type High frequency Location Rotation assembly Power rating (kW) 53.2 kV settings available 80, 100, 120, 140 10 - 440 (5mA steps) mA range and step size 80kV: 400 mA 100kV: 420 mA 120kV: 440 mA 140kV: 380 mA Max. mA allowed for each kV Table 28. X-ray tube GE LightSpeed RT Type and make GE Performix Pro Focal spot size(s) (mm), quoted to IEC 336/93 standard 0.6 x 0.7 0.9 x 0.9 Report 05070: GE LightSpeed RT CT scanner technical evaluation Settings at which focal spot changes. kW = kV x mA / 1000 24 kW Total filtration (inherent + beam shaping filter) at central axis (mm Al equivalent) 6.8 (70kV, head) 9.5 (70kV, body) Anode heat capacity (MHU) 6.3 Maximum anode cooling rate (kHU/min) 840 Method of cooling Glycol to air Guaranteed tube life 1 year unlimited guarantee Table 29. Detection system GE LightSpeed RT Solid state (HiLight / Lumex) Detector type Number of detectors per row 888 (plus 18 reference detectors) Number of elements along z-axis 16 Effective length of each element at isocentre (mm) 16 x 1.25 Total effective length of detector array at isocentre (mm) 20 Option for more slices / rotation 8-slice option available in future 28 Appendix 1. Scanner specifications Table 30. System start-up and calibration GE LightSpeed RT Power-on to warm-up time from fully off (mins) 2 Tube warm-up time from 'cold' to operating temperature (mins) 0.5 Time to perform detector calibrations at warmup (mins) Included in tube warm-up Recommended frequency for any additional calibration by the radiographer Once every 24 hours Time to perform these additional calibrations (mins) 13 (inc warm-up) Total time from fully off to scanning in an emergency (mins) <3 Table 31. Scan parameters GE LightSpeed RT kV settings available 80, 100, 120, 140 10 - 440 (5mA steps) Report 05070: GE LightSpeed RT CT scanner technical evaluation mA Range and Step size 80kV: 400 mA 100kV: 420 mA 120kV: 440 mA 140kV: 380 mA Max. mA allowed for each kV Maximum continuous scan time (s) 120 29 Appendix 1. Scanner specifications Table 32. Helical and axial scanning GE LightSpeed RT Rotation times for axial scaning (s) * = Partial scans 1, 2, 3, 4 Rotation times for helical scanning (s) 1 2 x 0.625, 1 x 1.25, 4 x 1.25, 1 x 2.5, 4 x 3.75, 4 x 5 Axial slice widths (number x width, mm) Helical acquisition widths (number of channels x width, mm) Info. not available Pitches available for routine scanning (range and increment) 2 slice : 1 4-slice : 0.75 & 1.5 Recommended pitches for optimal image quality 2 slice : 1 4-slice : 0.75 & 1.5 Helical interpolation algorithms available SmartHelical & MDMP, including CrossBeamTM & HyperplaneTM 70sec (350-440 mA) 90sec (280-415 mA) 110sec (240-345 mA) Report 05070: GE LightSpeed RT CT scanner technical evaluation Maximum number of rotations in one helical run at standard abdomen parameters Starting with a cold tube, the maximum helical scan distance using a 1 mm imaged slice thickness and a pitch of 1.5 (mm) 1600 Gantry tilt range for helical scanning (degrees) ± 30 Table 33. Scanned projection radiography (SPR) GE LightSpeed RT Maximum SPR length (mm) 1600 SPR field dimensions (mm x mm) 500 x 1600 Angular positions of X-ray tube available for SPR 0 - 359° (1° steps) Real time image No Accuracy of slice prescription from the scanogram (mm) ± 0.25 Accuracy of distance measurements from SPR's taken at isocentre (lateral and axial directions) (mm) < 2 x image pixel size 30 Appendix 1. Scanner specifications Table 34. Image reconstruction on main console Report 05070: GE LightSpeed RT CT scanner technical evaluation GE LightSpeed RT Reconstruction fields of view (cm) 9.6 - 50 Extended scan field of view (cm) 65 Reconstruction matrix 512 Minimum reconstruction interval in helical scanning (mm) 0.1 Reconstruction time from the start of data acquisition to the appearance of the 30th image of a series for a standard axial brain scan (s) 30 (with IBO) Reconstruction time from the start of data acquisition to the appearance of the 30th image of a series for an axial spine scan (s) <7 Sec Reconstruction time from the start of data acquisition to the appearance of the 30th image of a series for a helical abdomen scan (s) <7 Sec Simultaneous scanning and reconstruction Yes Any delay in either scanning or reconstruction when performed concurrently No Simultaneous scanning and routine analysis Yes Simultaneous scanning and archiving and/or hard copying Yes Simultaneous scanning and transfer to second console/workstation Yes 31 Appendix 1. Scanner specifications Table 35. Factors affecting image quality and dose GE LightSpeed RT Post-patient collimation for narrow slices No Automatic mA control (AEC / mA modulation) software 3D Dose Modulation - mA adjustment for patient size Yes - mA adjustment along the z-axis Yes - mA modulation during rotation Yes Number of helical gantry rotations required at each end of total imaged volume. Info. not available Adaptive filtration for noise reduction Low signal correction Quarter detector shift Yes Moving (dynamic/flying) focal spot, xy plane No Number of imaging detectors per row 888 Sampling frequency (Hz) Artefact reduction algorithms Iterative Bone Option (IBO), Recon of thick slices from thinner ones GE Proprietary algorithms (SmartHelical & MDMP, including CrossBeamTM & HyperplaneTM) Report 05070: GE LightSpeed RT CT scanner technical evaluation Cone beam correction 984 @ 1s scan (hardware capable to 1760) 32 Appendix 1. Scanner specifications Table 36. Manufacturer's performance data GE LightSpeed RT In plane spatial resolution (lp/cm) for sharpest clinical algorithm. Acquisition parameters in brackets. Contrast resolution: smallest rod size (mm) discernable at given parameters in 20 cm CATPHAN MTF0: 15.4 MTF10: 13.9 (10cm DFOV, Edge alg, Small Focus) 5mm @ 0.3% @ 13.3 mGy with 95%CL: 120kVp, 135mAs, 10mm, Std alg CT number accuracy (HU) Water : ± 3 CTDI100 settings for std head 120 kVp, 20 mm CTDI100 (mGy/100mAs), centre of head phantom Under review CTDI100 (mGy/100mAs), periphery of head phantom Under review Report 05070: GE LightSpeed RT CT scanner technical evaluation CTDI100 settings for std body 120 kVp, 20 mm CTDI100 (mGy/100mAs), centre of body phantom Under review CTDI100 (mGy/100mAs), periphery of body phantom Under review Dose profile FWHM (mm) (focal spot size in brackets) 20: 20.6(l) 15: 16.5 (s) 10: 11.5 (s) 5: 6.7 (s) 1.25: 3.5 (s) 2 x 0.63:1.9(s) Table 37. Operator's console GE LightSpeed RT Diagonal dimension of image screen (inches) 19 Number of monitors at console (functions of each if > 1) 2 (acquisition / review and processing) Image area matrix dimensions 512 x 512, 768 x 768, 1024 x 1024 Usual range of CT Number displayed (HU) -31743 to +31743 Accuracy of distance measurements in x-y plane (mm) < 2 times image pixel size Weighted CTDI (CTDIw or CTDIvol) displayed on console Yes Dose Length Product (DLP) displayed on console Yes Geometric Efficiency displayed on console when <70% Yes Control methods Mouse, trackball, keyboard 33 Appendix 1. Scanner specifications Table 38. Main computer GE LightSpeed RT Make and model HP XW8200 Operating system Linux SMP Kernel 2.6 Type and speed of CPU 2 x 3.2 GHz Amount of computer RAM supplied as standard (Gbytes) 2 Maximum amount of computer RAM (Gbytes) 12 Table 39. Image storage GE LightSpeed RT Total standard hard disk capacity (Gbytes) 291 Maximum hard disk capacity (Gbytes) 291 Hard disk capacity for image storage (Gbytes and no. of uncompressed 512x512 images) 146 (250,000 images) Hard disk capacity for storage of raw data files (Gbytes and no. of data files) 36(2881) 4-slice axial raw data files) Report 05070: GE LightSpeed RT CT scanner technical evaluation Archive options Capacity of a single archive disk (Gbytes and no. of images) MOD [images] & DVD [scan data, protocols] (standard) 4.6 (9400 losslessly compressed 512x512 images or 700 raw data files) Time to mount an archive disk or tape (s) 5-6 in background operation Archive data transfer rate (images / s) 1 (read) 0.7 (write) 34 Appendix 1. Scanner specifications Table 40. Independent workstation GE LightSpeed RT Is a workstation provided? Yes Computer make and model HP XW8200 Operating system Fedora Linux (Kernel 2.6) Type and speed (GHz) of CPU 2 x 3.4 Amount of computer RAM supplied as standard (Gbytes) 2 Maximum amount of computer RAM (Gbytes) 4 Total hard disk storage capacity supplied as standard (Gbytes) 182 Maximum total hard disk storage capacity (Gbytes) 182 CD-R standard MOD optional Archive options Capacity of a single archive disk (Gbytes) 4.6 Report 05070: GE LightSpeed RT CT scanner technical evaluation Environmental requirements (max/min temperature, humidity) for workstation 10-40 ºC, 20-80 % relative humidity Table 41. 3D reconstruction display on main console (MC) and workstation (WS) GE LightSpeed RT MIPs and MinIPs (maximum and minimum intensity projections) MC-standard WS-standard SSD (3D Shaded Surface Display) MC-option WS-standard 3D Volume rendering software MC-option WS-standard 3D Virtual endoscopy MC-option WS-standard MPR (Multi-planar reconstruction) MC-standard WS-standard Planes available in MPR Axial, para-axial, sagittal, coronal, oblique, curvilinear 35 Appendix 1. Scanner specifications Table 42. Optional facilities (MC = main console, WS = workstation) GE LightSpeed RT Contrast injector Option Contrast media bolus tracking Standard (SmartPrep) CT fluoroscopy software and hardware Option (SmartStep) Hard-copy imaging device Option Option (RT flat pad and Exact couch top) Radiotherapy planning table top Carbon fibre breast board Option Means for attaching patient immobilisation devices and a stereotactic frame to the end of the couch Option (Exact couch) MC-Not available WS-option (BMD) Bone Mineral Densitometry MC-standard WS-standard AVA (Vessel Assessment) option on WS CT Angiography MC-option WS-option (Dentascan) Dental MC-Not available WS-option (CT sim) Report 05070: GE LightSpeed RT CT scanner technical evaluation Radiotherapy CT simulation software Prospective ECG-triggered cardiac software MC-option WS-option (SmartScore) Retrospective ECG-gated cardiac software MC-Not available MC & WS-option (Cardiac Imaging) MC-option WS-option (CT Perfusion) CT Perfusion software 36 Appendix 1. Scanner specifications Table 43. Installation requirements GE LightSpeed RT Environmental requirements (max/min temperature, humidity) in scanner room 15-26 ºC, 30-60% relative humidity Environmental requirements (max/min temperature, humidity) in scanner control room 15-26 ºC, 30-60% relative humidity Peak heat output from system during scanning (kW) 15.3 System cooling method Output to air Air conditioning requirements for scanner room of minimum floor area Recommended Minimum floor area required for the system (m²) 28 Gantry dimensions (H x W x D (mm)) and weight (kg) Couch dimensions (H x W x L (mm)) and weight (kg) 1992x2439x1007 1701kg 1121x610x2387 330kg Power unit: 1067x711x559 350kg Supplementary unit dimensions (H x W x D (mm)) and weight (kg) 3 phase 380-480V, 150kVA Report 05070: GE LightSpeed RT CT scanner technical evaluation Power supply requirements 37 Appendix 1. Scanner specifications Table 44. Image transfer and connectivity GE LightSpeed RT Speed of scanner / workstation connections to local area networks (Mbits/s) 100 Remote PC access to images on workstation Option DICOM services on Main Console Storage SCU, SCP Print SCU Query / retrieve SCU, SCP Modality worklist Option Performed procedure step Option Storage commitment Not available DICOM services on Workstation Storage SCU, SCP Print SCU Query / retrieve SCU, SCP Not available Performed procedure step Not available Storage commitment Not available Report 05070: GE LightSpeed RT CT scanner technical evaluation Modality worklist management 38 Appendix 2. Manufacturer’s comments GE Healthcare are generally in agreement with the data in this report. They have made the following comments: Image Noise (page9) Our current LS RT product includes a lower noise Data Acquisition Subsystem (DAS) that was not available on the unit tested in November 2004. This DAS should improve the noise data under low signal conditions. Extended Field of View (pages 20 – 21) The primary requirement of the Wide View feature is to permit visualization of patient anatomy outside of the standard 50 cm DFOV to assist with radiation treatment planning. There is no expectation or requirement by GE to reproduce image quality to the same level and degree as within the 50 cm FOV. Report 05070: GE LightSpeed RT CT scanner technical evaluation GE recommends that the 100 mm water cylinder should remain adjacent to the larger phantom as they both move from isocentre to wider fields of view. We believe this phantom positioning is more representative of true clinical scenarios (arm or breast) used in radiation treatment planning. 39 Appendix 3. Image quality assessment and Q Image noise, scan plane spatial resolution and imaged slice width are fundamental parameters describing the amount of object information retrievable from an image, or its image quality. Radiation dose can be regarded as a 'cost' of this information. In general, it is meaningless to quote any one of these measurements without reference to the others. It is possible to incorporate dose, noise, spatial resolution and slice width into one number, using formulae derived from the relationships between image quality and dose. Figures of merit such as this can take a number of forms depending on how the various parameters are measured and quoted. ImPACT use the Q2 value, whose formula and methods of measurement are given below. High Q2 values result from CT scanners that produce images with lower noise at a set spatial resolution, when dose and image width are taken into account. The parameters used in Q are standard imaging performance parameters. However it should be noted that the quantification of perceived image quality is a complicated process and as such will not be fully described by the single descriptors used for each of the parameters. Report 05070: GE LightSpeed RT CT scanner technical evaluation Comparisons between scanners are more reliable when comparing scans reconstructed with similar convolution filters. The uncertainty in quoted values of Q2 is up to about ± 15 %, with a conservative estimate of ± 10 %. Q2 is calculated as follows: 3 fav Q2 = 2 σ z1CTDIvol σ = image noise, expressed as a percentage (for water, standard deviation in HU divided by 10), for a 5 cm2 region of interest at the centre of the field of view in the standard ImPACT water phantoms. fav = spatial resolution, given as (MTF50 + MTF10)/2, where MTF50 and MTF10 are the spatial frequencies corresponding to the 50 % and 10 % modulation transfer function values respectively (in line pairs per cm). Reconstruction algorithms with standard spatial resolution values are chosen to minimise the dependency of Q2 upon reconstruction algorithms. The reconstruction algorithm with MTF50 and MTF10 values as close as possible to 3.4 c/cm and 6.0 c/cm is used (c/mm used in the calculation for consistency of units with z-sensitivity). z1 = the full width at half maximum (FWHM) of the imaged slice profile (zsensitivity). This is measured using the inclined plates method (mm). CTDIvol = volume weighted CT dose index (mGy). 40 Appendix 4. ImPACT ImPACT ImPACT (Imaging Performance Assessment of Computed Tomography) is the Department of Health’s CT evaluation facility. It is based at St George's Hospital, London, part of St George's Healthcare NHS Trust. ImPACT has developed test objects and measurement procedures suitable for inter-comparing CT scanner performance. For each CT evaluation hundreds of images are obtained from the system under test and subsequently analysed using custom written software. Dose measurements are made using ion chambers, and x-ray film is used to obtain additional x-ray dose information. Support to purchasers and users The ImPACT team is available to answer any queries with regard to the details of this report, and also to offer general technical and user advice on CT purchasing, acceptance testing and quality assurance. Report 05070: GE LightSpeed RT CT scanner technical evaluation ImPACT Bence Jones Offices St George’s Hospital London SW17 0QT T: +44 (0) 20 8725 3366 F: +44 (0) 20 8725 3969 E: impact@impactscan.org W: www.impactscan.org 41