DEPARTMENT OF DRUG DESIGN AND PHARMACOLOGY FACULTY OF HEALTH AND MEDICAL SCIENCES UNIVERSITY OF COPENHAGEN Barriers and facilitators to implement drug changes caused by drug tenders and shortages R. Rishoej1, L. L. Christrup1, M. H. Clemmesen2 1Department 2The of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen Ø, Denmark. Danish Research Unit for Hospital Pharmacy (SAFE), AMGROS I/S, Dampfærgevej 22, 2100 Copenhagen Ø, Denmark. Background: Methods: Drug changes caused by drug tenders and shortages can Six focus group interviews were conducted at three hospitals in adversely affect patient safety and the working procedures different regions of Denmark. At each hospital two focus groups of healthcare professionals (1, 2). were conducted, one including physicians and nurses and one including pharmacists and pharmacy technicians, respectively. Objectives: The focus groups consisted of three to four participants. A semi- Identification of barriers and facilitators for implementing structured interview guide was applied and the interviews were drug changes due to drug tenders and shortages in audio-recorded, Danish public hospitals. categorized through content analysis. verbatim transcribed and thematically Results: Identified barriers and facilitators to implement drug changes were divided into the following categories: Barriers related to drug features Facilitators related to drug features - Frequent change of names, packages and labels complicates correct prescription and identification of drug in medication room - Barriers related to economics and organization Facilitators related to drug economics and organization - Drug tender rely on price and does not include other aspects such product characteristics and patient safety - Identification of drug substitute in case of drug shortage is time-consuming - Inclusion of the hospital pharmacy to a higher degree in the drug tender process - Improved national coordination and sharing of information on drug identification Barriers related to communication Facilitators related to communication - Inadequate and untimed information on drug changes from pharmacy to ward - Inadequate drug information provided in cases where a nonlicensed drug has to be used - Centralized preparation of drug information - Improved quality and timing of information Barriers related to technology Facilitators related to technology - Lack of quality and quality assurance of electronic systems - Inadequate education of health care professionals in the use of electronic systems - Implementation of clinical decision support in electronic physician order entry systems - Implementation of barcode scanning systems - Education of nurses and physicians in electronic order entry systems by hospital pharmacists Introduction of generic prescription Introduction of barcode scanning of packages Separation of look-a-like/sound-a-like drugs in medication room Written alerts in the medication room regarding drug changes Conclusion: In the present study barriers and facilitators for implementing drug changes were identified. The barriers and facilitators included features related to drugs, communication, health care technology as well as to economical and organizational aspects. Future studies should focus on alleviation of barriers and development and implementation of appropriate facilitators, which may improve patient safety and the working procedures of healthcare professionals during drug changes. References: 1: Hakonsen H. et al. Adv. Ther. 2010; 27: 118-126. 2: Fox ER, Tyler LS, Am. J. Health Syst. Pharm. 2003; 60: 245-253 EAHP 2015 – PS-109